Morphine-mimetic anti-paratypic antibodies: cross-reactive properties.

abstract：:Although brain natriuretic peptide (BNP) is a novel natriuretic peptide originally identified in porcine brain, recent investigation has verified the presence of BNP in porcine heart. In order to identify BNP as a circulating hormone, we analyzed the regional distribution and molecular form of immunoreactive (ir-) BNP...

journal_title：Biochemical and biophysical research communications

authors： Aburaya M,Minamino N,Kangawa K,Tanaka K,Matsuo H

更新日期：1989-12-15 00:00:00

abstract：:Nephrin is an important constituent of the glomerular filtration barrier and alteration of its expression is associated with severe proteinuria. In this study we show that injection of an anti-Thy1.1 antibody in rats not only induces a mesangioproliferative glomerulonephritis associated with increased proteinuria, but...

journal_title：Biochemical and biophysical research communications

authors： Schaefer L,Ren S,Schaefer RM,Mihalik D,Babelova A,Huwiler A,Pfeilschifter J

更新日期：2004-11-05 00:00:00

abstract：:Action potentials of myotubes in culture prepared from 18-19 day -old mouse embryos have a contractile activity and action potentials that are followed by a long lasting after hyperpolarization (ahp) which is blocked by apamin. Myotubes prepared from embryos of mice with muscular dysgenesis (mdg/mdg) did not contract ...

journal_title：Biochemical and biophysical research communications

authors： Romey G,Rieger F,Renaud JF,Pinçon-Raymond M,Lazdunski M

更新日期：1986-05-14 00:00:00

abstract：:Genes are organized as chromatin domains and positioned in the nucleus through regions of nuclear matrix association, termed MARs. Although well-studied, the mechanisms regulating expression of the beta-globin locus remain an enigma. Here, we show that certain MAR sequences of the beta-globin locus are conserved and r...

journal_title：Biochemical and biophysical research communications

authors： Walter WR,Singh GB,Krawetz SA

更新日期：1998-01-14 00:00:00

abstract：:The primary structure of the major hemoglobin component, HbA (alpha(A)- and beta-chain), from Tufted duck (Aythya fuligula) is presented. The separation of the globin subunits was achieved by ion exchange chromatography on CM-cellulose in 8 M urea. The amino acid sequence was determined by automatic Edman degradation ...

journal_title：Biochemical and biophysical research communications

authors： Abbasi A,Lutfullah G

更新日期：2002-02-15 00:00:00

abstract：:Heparin binding neurite-promoting factor (HBNF) is a highly basic 136 amino acid protein containing 10 cysteine residues. We have determined the redox status and the disulfide arrangement of the cysteine residues in HBNF from bovine brain and refolded human recombinant protein produced in E. coli. Our data indicate th...

journal_title：Biochemical and biophysical research communications

authors： Hulmes JD,Seddon AP,Decker MM,Böhlen P

更新日期：1993-04-30 00:00:00

abstract：:Lafora disease, a progressive myoclonus epilepsy, is an autosomal recessive disease caused in approximately 80% of cases by mutation of the EPM2A gene, which encodes a dual specificity protein phosphatase called laforin. In addition to its phosphatase domain, laforin contains an N-terminal carbohydrate-binding domain ...

journal_title：Biochemical and biophysical research communications

authors： Wang W,Roach PJ

更新日期：2004-12-17 00:00:00

abstract：:Experimental studies have demonstrated the beneficial effects of tetramethylpyrazine (TMP) against ischemic stroke and highlighted its crucial role in anti-inflammatory activity. This study provides evidence of an alternative target for TMP and sheds light on the mechanism of its anti-inflammatory action against ische...

journal_title：Biochemical and biophysical research communications

authors： Chang CY,Kao TK,Chen WY,Ou YC,Li JR,Liao SL,Raung SL,Chen CJ

更新日期：2015-07-31 00:00:00

abstract：:Enterolactone, a lignan that has been identified in biological samples from man and several mammals, shares with ascorbic acid and cardiac glycosides a gamma-butyrolactone. It displaces 3H-ouabain from its binding sites on cardiac digitalis receptor and inhibits, dose dependently, the Na+, K+-ATPase activity of human ...

journal_title：Biochemical and biophysical research communications

authors： Fagoo M,Braquet P,Robin JP,Esanu A,Godfraind T

更新日期：1986-02-13 00:00:00

abstract：:We examined the effects of angiotensin II (Ang II) on the proliferation of osteoblast-rich populations of cells obtained from calvariae of newborn rat. Addition of Ang II to the culture medium caused dose-dependent increases in the rate of DNA synthesis. Such increases were completely inhibited by the addition of DuP7...

journal_title：Biochemical and biophysical research communications

authors： Hiruma Y,Inoue A,Hirose S,Hagiwara H

更新日期：1997-01-03 00:00:00

abstract：:Previously, we have investigated the potential for a pro-oxidant interaction of iron and ascorbate in vivo in iron and ascorbate cosupplementation or ascorbate supplementation studies. In this study, for the first time, the effects of iron supplementation on oxidative damage to DNA in healthy individuals with plasma a...

journal_title：Biochemical and biophysical research communications

authors： Proteggente AR,England TG,Rice-Evans CA,Halliwell B

更新日期：2001-10-19 00:00:00

abstract：:We previously showed that NDP52 (also known as calcoco2) plays a role as an autophagic receptor for phosphorylated tau facilitating its clearance via autophagy. Here, we examined the expression and association of NDP52 with autophagy-regulated gene (ATG) proteins including LC3, as well as phosphorylated tau and amyloi...

journal_title：Biochemical and biophysical research communications

authors： Kim S,Lee D,Song JC,Cho SJ,Yun SM,Koh YH,Song J,Johnson GV,Jo C

更新日期：2014-11-07 00:00:00

abstract：:Metallothionein (MT) is believed to be a sensitive and effective "biomarker" for monitoring metal contamination in fish. Comparison of amino acid sequences between flounder MT and trout MT revealed that there is a conserved region at their N-terminals. Using oligonucleotides derived from this conserved region, reverse...

journal_title：Biochemical and biophysical research communications

authors： Chan KM

更新日期：1994-11-30 00:00:00

abstract：:Hypothetical lambda protein ORF314 shows significant homology with the carboxyl end of phage T4 tail-fiber protein gp37. Homology can also be demonstrated between hypothetical lambda protein ORF194 and a fragment of bacteriophage T4 protein gp38. This sequence homology is also reflected in the genomic sequences of the...

journal_title：Biochemical and biophysical research communications

authors： George DG,Yeh LS,Barker WC

更新日期：1983-09-30 00:00:00

abstract：:Since we recently reported that high density lipoprotein, which contains the bioactive lipid sphingosine-1-phosphate (S1P) [Arterioscler. Thromb. Vasc. Biol. 23 (2003) 802], induced human coronary artery endothelial cell (HCEC) tube formation mediated by a Ras/Raf/ERK (extracellular signal-activated kinase) pathway, w...

journal_title：Biochemical and biophysical research communications

authors： Miura S,Tanigawa H,Matsuo Y,Fujino M,Kawamura A,Saku K

更新日期：2003-07-11 00:00:00

abstract：:Human bone marrow cells express both a truncated and full-length form of the erythropoietin receptor (EpoR-T and EpoR-F, respectively). Transfection experiments using the murine interleukin (IL)-3-dependent cell line, Ba/F3, revealed that the cells coexpressing EpoR-F and EpoR-T (Ba/F3-FT) were more likely to undergo ...

journal_title：Biochemical and biophysical research communications

authors： Shimizu R,Komatsu N,Nakamura Y,Nakauchi H,Nakabeppu Y,Miura Y

更新日期：1996-05-06 00:00:00

abstract：:Various methods have been used to evaluate anti-fibrotic activity of drugs. However, most of them are complicated, labor-intensive and lack of efficiency. This study was intended to develop a rapid method for anti-fibrotic drugs screening based on biophysical properties. A549 cells in vitro were stimulated with transf...

journal_title：Biochemical and biophysical research communications

authors： Liu M,Zheng M,Xu H,Liu L,Li Y,Xiao W,Li J,Ma E

更新日期：2015-12-04 00:00:00

abstract：:The interest in adiponutrin stems from adiponutrin variant I148M, which is strongly associated to non-alcoholic fatty liver disease. Adiponutrin has to date been considered to be solely an intracellular protein, with a role in lipid metabolism in liver and adipose tissue. However, a physiologically relevant role for a...

journal_title：Biochemical and biophysical research communications

authors： Winberg ME,Motlagh MK,Stenkula KG,Holm C,Jones HA

更新日期：2014-04-18 00:00:00

abstract：:The post-translational modification of histones has been implicated in the regulation of cellular lifespan. Previously, we reported that cellular aging is associated with increased ubiquitylation of histone H2B and methylation of histone H3 at lysines 4 and 79 in yeast telomeric heterochromatin. Here, we show the anta...

journal_title：Biochemical and biophysical research communications

authors： Ryu HY,Rhie BH,Ahn SH

更新日期：2014-03-28 00:00:00

abstract：:ERRalpha (estrogen receptor-related receptor alpha) is a member of the nuclear receptor superfamily. To further our understanding of the detailed molecular mechanism of transcriptional regulation by ERRalpha, we searched for ERRalpha-interacting proteins using a yeast two-hybrid system by screening a human mammary gla...

journal_title：Biochemical and biophysical research communications

authors： Li Y,Chen B,Chen J,Lou G,Chen S,Zhou D

更新日期：2008-05-16 00:00:00

abstract：:It is well-known that electrical stimulation can prompt healing of bone fractures. However, the mechanism involved is less clear. In this study, we found that capacitively coupled electric field-induced proliferation of osteoblastic cells (MC3T3-E1) accompanied increased levels of transforming growth factor-beta 1 (TG...

journal_title：Biochemical and biophysical research communications

authors： Zhuang H,Wang W,Seldes RM,Tahernia AD,Fan H,Brighton CT

更新日期：1997-08-18 00:00:00

abstract：:We found citrulline-containing proteins in mouse peritoneal macrophages undergoing calcium ionophore-induced apoptosis. Such proteins were products of deimination of arginine residues catalyzed by endogenous peptidylarginine deiminase (EC 3.5.3.15) activated by calcium influx. Western blotting analyses of the extract ...

journal_title：Biochemical and biophysical research communications

authors： Asaga H,Yamada M,Senshu T

更新日期：1998-02-24 00:00:00

abstract：:FOXP3 is known as a master control of regulatory T cells with recently studies indicating its expression in several tumor cells. In order to study the precise role of FOXP3 in cholangiocarcinoma, FOXP3 was knocked down in cholangiocarcinoma cell lines. Down regulation of FOXP3 inhibits tumor cell invasion by reducing ...

journal_title：Biochemical and biophysical research communications

authors： Ma C,Peng C,Lu X,Ding X,Zhang S,Zou X,Zhang X

更新日期：2015-03-06 00:00:00

abstract：:We have mapped the DNase I hypersensitive sites (DH-sites) of the 5' region of the fibronectin (FNT) gene of the liver of the rat. These sites are not detectable in the cerebral hemisphere of the rat. Northern blot hybridization of the gene shows the presence of a 8 kb transcript in the liver which is induced by dexam...

journal_title：Biochemical and biophysical research communications

authors： Singh S,Kanungo MS

更新日期：1991-11-27 00:00:00

abstract：:Cytochromes P450 2E1 of human and minipig origin were examined by absorption spectroscopy under high hydrostatic pressure and by resonance Raman spectroscopy. Human enzyme tends to denature to the P420 form more easily than the minipig form; moreover, the apparent compressibility of the heme active site (as judged fro...

journal_title：Biochemical and biophysical research communications

authors： Anzenbacherova E,Hudecek J,Murgida D,Hildebrandt P,Marchal S,Lange R,Anzenbacher P

更新日期：2005-12-09 00:00:00

abstract：:The mechanism(s) by which HIV-1 infection contributes to depletion of CD4(+) T cell is not well understood. In this report, we investigated whether a recently identified isoform of growth factor receptor bound protein (Grb2), named Grb3-3, a signaling molecule that is associated with the MAP kinase pathway and with ap...

journal_title：Biochemical and biophysical research communications

authors： Li X,Multon MC,Henin Y,Schweighoffer F,Venot C,LaVecchio J,Josef J,Stuckert P,Mhashilkar A,Tocqué B,Marasco WA

更新日期：2000-09-16 00:00:00

abstract：:Saccharides used in clinical nutrients and the hyperglycemia status may facilitate tumor growth and aggravate cancer patients' outcome. As glucose, fructose and maltodextrin are widely used in clinical practice, various effects on tumor progress among them remain unknown. Six kinds of tumor cell lines were included in...

journal_title：Biochemical and biophysical research communications

authors： Yu C,Lv B,Min S,Ren L,Yu J

更新日期：2020-05-07 00:00:00

abstract：:The mouse disabled 2 interacting protein 2 (mDaIP2) had been obtained through yeast two hybrid system. It consists of 506 amino acids and its calculated molecular weight is 57.7 kDa. The protein contains N-terminal FCH domain and C-terminal SH3 domain. The SH3 domain interacts with the proline rich domain of mDab2 whi...

journal_title：Biochemical and biophysical research communications

authors： Choi YJ,Cho SY,Kim HW,Kim JA,Bae SH,Park SS

更新日期：2005-01-21 00:00:00

abstract：:In Saccharomyces cerevisiae, the bud site selection of diploid cells is regulated by at least four persistent landmarks, Bud8p, Bud9p, Rax1p, and Rax2p. Bud8p and Bud9p are essential for the establishment of bipolar budding and localize mainly to the distal and the proximal poles, respectively. Their subcellular local...

journal_title：Biochemical and biophysical research communications

authors： Kato Y,Kawasaki H,Arakawa N,Hirano H

更新日期：2010-09-03 00:00:00

abstract：:Liraglutide, a glucagon-like peptide 1 (GLP-1) analogue, could reverse NAFLD-induced liver damage by improving metabolic profiles, but the exact molecular mechanism has not been elucidated. Sestrin2 is a novel antioxidant protein, essential for regulating metabolic homeostasis. However, whether sestrin2-mediated redox...

journal_title：Biochemical and biophysical research communications

authors： Han X,Ding C,Zhang G,Pan R,Liu Y,Huang N,Hou N,Han F,Xu W,Sun X

更新日期：2020-05-14 00:00:00