Abstract:
:Ascletis has developed danoprevir (Ganovo®), an orally-administered hepatitis C virus NS3 protease inhibitor, as a treatment for hepatitis C. Based on positive results in phase II and phase III trials in patients with hepatitis C, danoprevir, in combination with ritonavir, peginterferon alfa and ribavirin was recently approved for marketing in China for the treatment of treatment-naive patients with non-cirrhotic genotype 1b chronic hepatitis C. This article summarizes the milestones in the development of danoprevir leading to this first approval.
journal_name
Drugsjournal_title
Drugsauthors
Markham A,Keam SJdoi
10.1007/s40265-018-0960-0subject
Has Abstractpub_date
2018-08-01 00:00:00pages
1271-1276issue
12eissn
0012-6667issn
1179-1950pii
10.1007/s40265-018-0960-0journal_volume
78pub_type
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