Abstract:
:The mono-site mutations of the absolutely conserved residues, (464)LGR(466), in the α-helix 5 (h5) of HPV16 L1 completely disrupted the pentamer formation. The implication of this finding is the potential usage of a h5-like peptide as the reagent to interfere with the pentamer formation and stability as an anti-HPV reagent.
journal_name
Mol Biosystjournal_title
Molecular bioSystemsauthors
Jin S,Pan D,Zha X,Yu X,Wu Y,Liu Y,Yin F,Chen XSdoi
10.1039/c3mb70550asubject
Has Abstractpub_date
2014-04-01 00:00:00pages
724-7issue
4eissn
1742-206Xissn
1742-2051journal_volume
10pub_type
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