Carvone Contact Allergy in Southern Sweden: A 21-year Retrospective Study.

Abstract:

:Carvone (l-carvone), a mint flavour in spearmint oil, is considered a mild skin sensitizer. Carvone-sensitization may be linked to oral/perioral signs and oral lichen planus, but studies are sparse. The prevalence of patch test reactions to carvone and relevant findings from the positive group were investigated. Records for patch-tested patients at the Malmö clinic, for the period 1996 to 2016, were studied. Carvone-positive and carvone-negative patients were compared regarding patch test data from baseline series and dental series. Dental series-tested carvone-positive patients were also compared with a matched group. A total of 147 out of 4,221 referred patients had a positive patch test to carvone. Sensitized patients had higher mean age and were primarily women; 73% had oral signs and 57% had oral lichen. Concomitant patch test reactions to gold, nickel and mercury were common. In the matched group-comparison carvone-positive patients had a higher frequency of oral lichen, but no difference was found in sensitization to gold and mercury.

journal_name

Acta Derm Venereol

authors

Kroona L,Isaksson M,Ahlgren C,Dahlin J,Bruze M,Warfvinge G

doi

10.2340/00015555-3009

subject

Has Abstract

pub_date

2018-11-05 00:00:00

pages

938-942

issue

10

eissn

0001-5555

issn

1651-2057

journal_volume

98

pub_type

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