Abstract:
BACKGROUND:Proteinuria is among the major and nonspecific sign of the renal disease. It is well known that late-onset proteinuria after renal transplantation has been associated with poor allograft outcomes and with mortality. Knowledge about the impact of early proteinuria on the various outcomes is limited. We have evaluated the utility of measuring early proteinuria in the management of pediatric renal transplant recipients. METHODS:We analyzed the effect of proteinuria at 3 months of posttransplantation on allograft rejection, graft loss, and estimated glomerular filtration rate (GFR) at 3 years. Proteinuria was assessed using 24-hour urine protein excretion. Renal biopsy was performed when elevated creatinine levels were elevated during routine follow-up and an acute rejection episode was proven with biopsy. RESULTS:Sixty-seven pediatric renal transplant recipients were included to the study. Mean follow-up time after transplantation was 48.8 ± 12.1 months. Thirty-nine recipients (58%) have proteinuria >500 mg/d. The relationship could not be shown between proteinuria at posttransplant month 3 and other outcomes parameters, such as graft loss and lower estimated GFR. A significant positive correlation between acute rejection and the proteinuria at posttransplant month 3 was shown. CONCLUSION:We demonstrated that early proteinuria is a common finding in children after transplantation. Posttransplant early proteinuria cannot be used as a long-term prognostic marker of poor renal outcome. However, early proteinuria is associated with an high risk of acute rejection episodes. This would permit an opportunity for early intervention.
journal_name
Transplant Procjournal_title
Transplantation proceedingsauthors
Gulleroglu K,Baskin E,Bayrakci U,Akdur A,Moray G,Haberal Mdoi
10.1016/j.transproceed.2013.06.022subject
Has Abstractpub_date
2014-01-01 00:00:00pages
141-4issue
1eissn
0041-1345issn
1873-2623pii
S0041-1345(13)01143-3journal_volume
46pub_type
杂志文章abstract::Pancreas and kidney transplantation is the treatment of choice for patients with type 1 diabetes mellitus and terminal renal insufficiency. Herein we have presented a series of 35 patients transplanted between 2002 and 2009 including periods before and after 2007 divided based on introduction of some technical aspects...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2009.12.001
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:There have been many efforts to find methods to increase insulin production by islets or modified cells. Commercially available established cell lines can be a good source of artificial islets. We manufactured sphere-shaped cell clusters composed of insulin-secreting cells from the commercially available RIN...
journal_title:Transplantation proceedings
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journal_title:Transplantation proceedings
pub_type: 杂志文章,评审
doi:10.1016/j.transproceed.2011.02.036
更新日期:2011-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2016.04.008
更新日期:2016-07-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2009.04.015
更新日期:2009-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2014.06.011
更新日期:2014-07-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2007.01.034
更新日期:2007-03-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章,评审
doi:10.1016/s0041-1345(98)00670-8
更新日期:1998-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2004.12.167
更新日期:2005-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2005.03.144
更新日期:2005-05-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2018.04.010
更新日期:2018-10-01 00:00:00
abstract:INTRODUCTION:Our aim in this study was to investigate the prevalence and correlation with coronary artery calcium scores (CACS) and erectile dysfunction (ED) among hemodialysis patients. PATIENTS AND METHODS:Thirty-five male patients with chronic renal failure were selected to participate in this study. All patients u...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2007.11.046
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Kidney transplant patients with D+/R+ serology can be treated with either prophylaxis or preemptive valganciclovir. The older transplant population suffers severe immunosenescence, especially patients with latent cytomegalovirus (CMV) infection (R+). They are more likely to develop indirect CMV effects. Like...
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2016.06.062
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Patients undergoing urgent heart transplantation (HT) have a poorer prognosis and more long-term complications. The objective of this study was to compare the preoperative course in patients undergoing urgent HT according to the need for preoperative intra-aortic balloon counterpulsation (IABP). MATERIALS A...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2008.08.114
更新日期:2008-11-01 00:00:00
abstract::Cardiovascular disease is a major cause of morbidity and mortality in children and young adults with end-stage renal disease. In our study, we retrospectively analyzed the records of 11 patients who had undergone electron beam computerized tomography in our dialysis unit. Our patients, aged 11 to 24 years (median, 19....
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2006.10.198
更新日期:2007-01-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2019.02.046
更新日期:2019-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2006.05.051
更新日期:2006-07-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2012.07.107
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Living donor transplantation (LDT) using kidneys with multiple arteries (MA) has previously been reported to be associated with increased complications and poorer outcomes in recipients. The objective of this study was to investigate outcomes of LDT with MA at the National University Hospital of Singapore, a...
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2015.12.104
更新日期:2016-04-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2019-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-12-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2005-06-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2006.10.215
更新日期:2007-01-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2005.09.013
更新日期:2005-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2004.12.241
更新日期:2005-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2005.09.076
更新日期:2005-10-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2010.05.110
更新日期:2010-07-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2008.03.120
更新日期:2008-05-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 临床试验,杂志文章
doi:10.1016/j.transproceed.2007.07.012
更新日期:2007-09-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2009.03.057
更新日期:2009-06-01 00:00:00