Reduced acetylcholine-induced channel activity in dystrophic mouse myotubes.

abstract：:Propriospinal myoclonus (PSM) is a rare movement disorder characterized by involuntary axial jerks originating from muscles innervated by multiple spinal segments. Most cases of PSM are idiopathic. Gluten sensitivity is a multisystemic autoimmune condition which may be associated with various neurological disorders, m...

journal_title：Journal of the neurological sciences

authors： Zhang Y,Menkes DL,Silvers DS

更新日期：2012-04-15 00:00:00

abstract：:Amyotrophic Lateral Sclerosis (ALS) occurs more commonly in men than in women, and women get the disease later in life compared to men. This epidemiologic aspect of the disease raises the question as to whether estrogen may be neuroprotective in delaying or preventing ALS. Postmenopausal women with ALS were separated ...

journal_title：Journal of the neurological sciences

authors： Rudnicki SA

更新日期：1999-10-31 00:00:00

abstract：:Thalamic damage is associated with a variety of neuropsychological dysfunctions, as well as strategic infarct dementia. However, only a limited number of reports in the medical literature have discussed the correlation between the clinical findings and the specific functional changes observed on images. We investigate...

journal_title：Journal of the neurological sciences

authors： Shim YS,Kim JS,Shon YM,Chung YA,Ahn KJ,Yang DW

更新日期：2008-03-15 00:00:00

abstract：:Clinico-anatomical correlations in multiple sclerosis patients presenting with central positional vertigo are lacking. We report on a patient with acute onset positional vertigo mimicking benign paroxysmal positional vertigo with a single enhancing lesion in the inner part of the superior cerebellar peduncle, disclose...

journal_title：Journal of the neurological sciences

authors： Anagnostou E,Varaki K,Anastasopoulos D

更新日期：2008-03-15 00:00:00

abstract：:The retrovirus that causes the acquired immunodeficiency syndrome (AIDS) has two targets: the immune system and the nervous system. Central nervous system (CNS) manifestations of AIDS are protean. This review describes the opportunistic infections and malignancies that affect the nervous system in AIDS, and discusses ...

journal_title：Journal of the neurological sciences

authors： Tucker T

更新日期：1989-02-01 00:00:00

abstract：:To elucidate the T helper 1 (Th1)/T helper 2 (Th2) balance in various inflammatory neuropathies, we measured the ratio of intracellular interferon-gamma (IFN-gamma)-positive to IL-4-positive cells (intracellular IFN-gamma/IL-4 ratio) by flow cytometry in peripheral blood CD4(+) T cells of 14 patients with mononeuritis...

journal_title：Journal of the neurological sciences

authors： Horiuchi I,Ochi H,Murai H,Osoegawa M,Minohara M,Furuya H,Kira J

更新日期：2001-12-15 00:00:00

abstract：:Bacillus Calmette-Guérin (BCG) and Mycobacterium avium subspecies paratuberculosis (MAP) have been associated with multiple sclerosis (MS). Clinical data indicates that BCG vaccination exerts anti-inflammatory effects in MS; conversely, MAP is thought to be one of the possible infectious factors responsible of MS thro...

journal_title：Journal of the neurological sciences

authors： Cossu D,Mameli G,Masala S,Cocco E,Frau J,Marrosu MG,Sechi LA

更新日期：2014-12-15 00:00:00

abstract：:We report a 17-year-old man showing myoclonic involuntary movement (IVM) associated with chronic manganese (Mn) poisoning. The patient, a welder, showed myoclonic IVM mainly in the right upper and lower extremities, elevated levels of Mn in the blood and hair and high-intensity signals in the globus pallidus on T1-wei...

journal_title：Journal of the neurological sciences

authors： Ono K,Komai K,Yamada M

更新日期：2002-07-15 00:00:00

abstract：:Glucose-6-phosphate dehydrogenase (G6PDH), 6-phosphogluconate dehydrogenase (6PGDH) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) activities were assayed in superficial pectoral muscles of hereditary dystrophic chickens, 1 week, 2 weeks, 4 weeks and 4 months after hatching. In control chickens, activities of G6...

journal_title：Journal of the neurological sciences

authors： Mizuno Y

更新日期：1985-04-01 00:00:00

abstract：:Fingerprint inclusions were identified in the skeletal muscle of a child with severe hypotonia. The mean Z-line and M-line widths from each of 19 muscle fibers containing the fingerprint inclusions were calculated. The mean Z-line widths were 85-99 nm, and the mean M-line widths were 75-101 nm. According to out presen...

journal_title：Journal of the neurological sciences

authors： Payne CM,Curless RG

更新日期：1977-04-01 00:00:00

abstract：:Multiple sclerosis patients, control patients with other neurological diseases, and normal volunteers were assayed in a short-term 51chromium release assay for cell-mediated cytotoxicity against lymphocyte targets coated with myelin basic protein. Multiple sclerosis patients, compared to the other two groups, were hyp...

journal_title：Journal of the neurological sciences

authors： Eggers AE,Tarmin L,Plank CR,Gamboa ET

更新日期：1981-11-01 00:00:00

abstract：PURPOSE:This study aimed to evaluate the risk factors, etiology, and outcomes of ischemic stroke (IS) in Japanese young adults. METHODS:This was a prospective multicenter study. We enrolled patients aged 16 to 55 years with IS within seven days of the onset of symptoms. We assessed the demographic data, risk factors, ...

journal_title：Journal of the neurological sciences

authors： Kono Y,Terasawa Y,Sakai K,Iguchi Y,Nishiyama Y,Nito C,Suda S,Kimura K,Kanzawa T,Imafuku I,Nakayama T,Ueda M,Iwanaga T,Kono T,Yamashiro K,Tanaka R,Okubo S,Nakajima M,Nakajima N,Mishina M,Yaguchi H,Oka H,Suzuki

更新日期：2020-10-15 00:00:00

abstract：UNLABELLED:The King-Devick (KD) oculomotor test has recently been advocated for sideline diagnosis of concussion. Although visual processing and performance are often impaired in concussion patients, the utility of KD as a concussion diagnostic tool is not validated. PURPOSE:To examine the diagnostic value of KD, by c...

journal_title：Journal of the neurological sciences

authors： Tjarks BJ,Dorman JC,Valentine VD,Munce TA,Thompson PA,Kindt SL,Bergeron MF

更新日期：2013-11-15 00:00:00

abstract：INTRODUCTION:Whether motor neuron diseases (MNDs) can be considered in some cases of paraneoplastic syndromes is controversial. We report a case of rapidly progressive motor neuronopathy following a diagnosis of breast carcinoma, with a presence of anti-Ri antibodies, and a novel SOD1 gene mutation. OBSERVATION:An 80-...

journal_title：Journal of the neurological sciences

authors： Diard-Detoeuf C,Dangoumau A,Limousin N,Biberon J,Vourc'h P,Andres CR,de Toffol B,Praline J

更新日期：2014-02-15 00:00:00

abstract：:The product of the permeability x vascular surface rate area (PA) of the blood-brain barrier to [14C]sucrose has been measured in rats raised on synthetic diets in which the saturated/unsaturated fat constitution was controlled at high or low levels. Gas-liquid chromatography demonstrated marked differences in brain f...

journal_title：Journal of the neurological sciences

authors： Phillips SC,Cragg BG,Sinclair AJ

更新日期：1982-05-01 00:00:00

abstract：:To compare muscle fiber loss in young and old mdx mice, we have blocked regeneration in one leg with a high dose (18 Gy) of X-rays administered at two ages; 16 days, just prior to the onset of the myopathy, and 15 weeks, when the myopathy is considered to be quiescent. Mice were examined 4 days after irradiation to lo...

journal_title：Journal of the neurological sciences

authors： Pagel CN,Partridge TA

更新日期：1999-04-01 00:00:00

abstract：:We report a novel heteroplasmic mutation p.Y440C in the mitochondrial DNA-encoded subunit I of the cytochrome c oxidase (COX) gene in a patient with late onset progressive painless weakness. Her muscle biopsy showed scattered COX-negative fibers and several small collections of inflammatory cells. The mutation was det...

journal_title：Journal of the neurological sciences

authors： Massie R,Wang J,Chen LC,Zhang VW,Collins MP,Wong LJ,Milone M

更新日期：2012-08-15 00:00:00

abstract：:Patients with Mild Cognitive Impairment (MCI) have a greater risk of developing dementia than general population. Lots of evidence suggests that cardiovascular risk factors appear more often in the MCI than in general population The aim of this study was to evaluate association between cardiovascular risk factors and ...

journal_title：Journal of the neurological sciences

authors： Siuda J,Gorzkowska A,Opala G,Ochudło S

更新日期：2007-06-15 00:00:00

abstract：:HS1-associated protein X-1 (HAX-1) and presenilin-associated rhomboid-like protein (PALR) were reported to play an important role in the activation of HtrA2/Omi, which is also designated PARK13, in the mitochondria. To elucidate the role of HAX-1 and PARL in patients with Parkinson's disease (PD) and dementia with Lew...

journal_title：Journal of the neurological sciences

authors： Kawamoto Y,Ayaki T,Urushitani M,Ito H,Takahashi R

更新日期：2020-08-15 00:00:00

abstract：OBJECTIVE:It has been suggested that autoantibodies may induce axonal damage in multiple sclerosis (MS). Optical coherence tomography (OCT) showed that thinning of peripapillary retinal nerve fiber layer (RNFL) and ganglion cell layer/inner plexiform (GCIPL) measurements reflect axonal loss in the disease. We investiga...

journal_title：Journal of the neurological sciences

authors： Álvarez-Cermeño JC,Muñoz-Negrete FJ,Costa-Frossard L,Sainz de la Maza S,Villar LM,Rebolleda G

更新日期：2016-01-15 00:00:00

abstract：:The findings of various studies reporting temporal changes in CSF total nitrite/nitrate (NOx) levels after subarachnoid hemorrhage (SAH) vary considerably. The study group comprised 10 patients with SAH and 10 control subjects. Total nitrite/nitrate concentration was measured by a vanadium-based assay with the colorim...

journal_title：Journal of the neurological sciences

authors： Rejdak K,Petzold A,Sharpe MA,Kay AD,Kerr M,Keir G,Thompson EJ,Giovannoni G

更新日期：2004-04-15 00:00:00

abstract：:Controversy exists regarding the apolipoprotein E (ApoE) epsilon 4 allele association with vascular dementia (VaD). The results range from increased epsilon 4 frequency, similar to that found for Alzheimer's disease (AD), to no association at all. Our objective was to clarify the relationship between ApoE epsilon 4 al...

journal_title：Journal of the neurological sciences

authors： Traykov L,Rigaud AS,Baudic S,Smagghe A,Boller F,Forette F

更新日期：2002-11-15 00:00:00

abstract：:Water-suppressed proton magnetic resonance spectroscopy which has recently shown diagnostic potential in human stroke victims was performed in two patients who had suffered a hemispheric transient ischemic attack. Localized spectra were targeted from routine MR images. In one patient lactate could be observed 8 weeks ...

journal_title：Journal of the neurological sciences

authors： Felber S,Luef G,Aichner F

更新日期：1992-03-01 00:00:00

abstract：:Ultrastructural alterations were observed in the sciatic nerve of dystrophic mice. Myelin sheaths were abnormal in shape, abruptly ceased beyond a node of Ranvier, leaving the axon naked. These changes were seen in both afferent and efferent nerve fibres. Apparent embryonal Schwann cells and Schwann cells which were a...

journal_title：Journal of the neurological sciences

authors： Okada E,Mizuhira V,Nakamura H

更新日期：1976-08-01 00:00:00

abstract：:We describe a patient with progressive aphemia with agrammatism that was later overlaid with buccofacial apraxia and pseudobulbar palsy. Pathological findings were consistent with those of classic Pick's disease with argyrophilic inclusions and neuronal achromasia, except for restricted cortical atrophy in the frontal...

journal_title：Journal of the neurological sciences

authors： Sakurai Y,Murayama S,Fukusako Y,Bando M,Iwata M,Inoue K

更新日期：1998-08-14 00:00:00

abstract：:Psychiatric disorders seem to be more frequent in patients with epilepsy (PWE) than the general population. Although researchers have documented a strong association between epilepsy and psychiatric comorbidities, the nature of this relationship is poorly understood. According to this, psychiatric diseases are often u...

journal_title：Journal of the neurological sciences

authors： Verrotti A,Carrozzino D,Milioni M,Minna M,Fulcheri M

更新日期：2014-08-15 00:00:00

abstract：:An improved method for identification of CSF and serum proteins is described, using analytical isoelectric focusing followed by direct immunofixation in polyacrylamide gel. This method offers high sensitivity together with retained resolution after isoelectric focusing and is technically easy to perform. The gamma-tra...

journal_title：Journal of the neurological sciences

authors： Stibler H

更新日期：1979-07-01 00:00:00

abstract：:Neocortical lesions (NLs) are an important component of multiple sclerosis (MS) pathology and may account for part of the physical and cognitive disability. Visualizing NLs of patients with MS using magnetic resonance imaging (MRI) poses several significant challenges. We optimized the inversion time (TI) of T(1)-base...

journal_title：Journal of the neurological sciences

authors： Bagnato F,Yao B,Cantor F,Merkle H,Condon E,Montequin M,Moore S,Quezado M,Tkaczyk D,McFarland H

更新日期：2009-07-15 00:00:00

abstract：OBJECTIVE:To describe the clinical characteristics, delay to diagnosis and post-intervention outcomes of patients with low-flow spinal arteriovenous fistulas (SAVFs). METHODS:In this retrospective observational study, we reviewed all patients with low-flow SAVFs angiographically diagnosed at our institution between 20...

journal_title：Journal of the neurological sciences

authors： Murphy OC,Hedjoudje A,Salazar-Camelo A,Pardo CA,Gailloud P

更新日期：2020-06-15 00:00:00

abstract：:Wernicke's encephalopathy is often undiagnosed, particularly in non-alcoholics. There are very few reports of non-alcoholic patients diagnosed with Korsakoff syndrome in the absence of a prior diagnosis of Wernicke's encephalopathy and no studies of diffusion tensor imaging in non-alcoholic Korsakoff syndrome. We repo...

journal_title：Journal of the neurological sciences

authors： Nikolakaros G,Ilonen T,Kurki T,Paju J,Papageorgiou SG,Vataja R

更新日期：2016-11-15 00:00:00