Abstract:
:Mesenchymal stem cells (MSCs) are defined as pluripotent cells found in numerous human tissues, including bone marrow and adipose tissue. Such MSCs, isolated from bone marrow and adipose tissue, have been shown to differentiate into bone and cartilage, along with other types of tissues. Therefore, MSCs represent a promising new therapy in regenerative medicine. The initial treatment of meniscus tear of the knee is managed conservatively with nonsteroidal anti-inflammatory drugs and physical therapy. When such conservative treatment fails, an arthroscopic resection of the meniscus is necessary. However, the major drawback of the meniscectomy is an early onset of osteoarthritis. Therefore, an effective and noninvasive treatment for patients with continuous knee pain due to damaged meniscus has been sought. Here, we present a review, highlighting the possible regenerative mechanisms of damaged meniscus with MSCs (especially adipose tissue-derived stem cells (ASCs)), along with a case of successful repair of torn meniscus with significant reduction of knee pain by percutaneous injection of autologous ASCs into an adult human knee.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Pak J,Lee JH,Lee SHdoi
10.1155/2014/436029subject
Has Abstractpub_date
2014-01-01 00:00:00pages
436029eissn
2314-6133issn
2314-6141journal_volume
2014pub_type
杂志文章,评审abstract:Objectives:The purpose of the study was to evaluate the correlation between dynamic test results obtained on a stabilometric platform and the results achieved on the Y-balance test (Y-BT). Method:The study group consisted of 52 adolescent athletes, aged 14 to 17 years. Each participant was evaluated in the scope of th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6968473
更新日期:2020-11-12 00:00:00
abstract::Cognitive dysfunction is an important complicated disease in obesity. Exercise ameliorates obesity and the related cognitive dysfunction. However, the underlying mechanism is still unclear. In this study, we investigated whether aerobic interval training (AIT) could attenuate high-fat-diet- (HFD-) associated cognitive...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/2708491
更新日期:2018-03-22 00:00:00
abstract::Effects of ketamine and lidocaine on electroencephalographic (EEG) changes were evaluated in minimally anaesthetized dogs, subjected to electric stimulus. Six dogs were subjected to six treatments in a crossover design with a washout period of one week. Dogs were subjected to intravenous boluses of lidocaine 2 mg/kg, ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/305367
更新日期:2015-01-01 00:00:00
abstract::The receptor activator of NF-κB (RANK) pathway is involved in bone health as well as breast cancer (BC) pathogenesis and progression. Whereas the therapeutic implication of this pathway is established for the treatment of osteoporosis and bone metastases, the application in adjuvant BC is currently investigated. As ge...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1155/2014/842452
更新日期:2014-01-01 00:00:00
abstract::Ablative therapies have been utilized with increasing frequency for the treatment of Barrett's esophagus with and without dysplasia. Multiple modalities are available for topical ablation of the esophagus, but radiofrequency ablation (RFA) remains the most commonly used. There have been significant advances in techniq...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/642063
更新日期:2014-01-01 00:00:00
abstract::Hypertension and atherosclerosis are among the most common causes of mortality in both developed and developing countries. Experimental animal models of hypertension and atherosclerosis have become a valuable tool for providing information on etiology, pathophysiology, and complications of the disease and on the effic...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/528757
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:Identification of the factors that influence sedentary behaviour in older adults is important for the design of appropriate intervention strategies. In this study, we determined the prevalence of sedentary behaviour and its association with physical, cognitive, and psychosocial status among older adults resid...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/9160504
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:Abnormal expression of ABCA1 and ABCG1 in the placenta can elicit lipid metabolism disorder and adverse pregnancy outcomes. However, whether it is associated with preterm delivery remains unclear. Our present study aimed to evaluate the relationship between abnormal expression of ABCA1 or ABCG1 and preterm de...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2017/8248094
更新日期:2017-01-01 00:00:00
abstract::The effects of obstruction on renal function are the consequence of many factors that profoundly alter all components of glomerular function. Besides the acute effects on glomerular filtration rate and tubule function, a chronic obstruction induces tubular and interstitial injury that results from the activation of di...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/303298
更新日期:2014-01-01 00:00:00
abstract::RRM2B gene encodes ribonucleoside-diphosphate reductase subunit M2 B, the p53-inducible small subunit (p53R2) of ribonucleotide reductase (RNR), an enzyme catalyzing dNTP synthesis for mitochondrial DNA. Defects in this gene may cause severe mitochondrial disease affecting mainly the nervous system. This study is aime...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/7614634
更新日期:2020-07-25 00:00:00
abstract::The goal of this study was to analyse perceptually and acoustically the voices of patients with Unilateral Vocal Fold Paralysis (UVFP) and compare them to the voices of normal subjects. These voices were analysed perceptually with the GRBAS scale and acoustically using the following parameters: mean fundamental freque...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/704121
更新日期:2015-01-01 00:00:00
abstract:Background:The present study aims to investigate the incidence and risk factors associated with postoperative delirium in patients undergoing spine surgery. Methods:PubMed, EMBASE, Cochrane Library, and Science Citation Index were searched up to August 2019 for studies examining postoperative delirium following spine ...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2019/2139834
更新日期:2019-11-26 00:00:00
abstract:Aims:To evaluate the effectiveness and safety of peritoneal dialysis (PD) in treating refractory congestive heart failure (RCHF) with cardiorenal syndrome (CRS). Methods:A total of 36 patients with RCHF were divided into type 2 CRS group (group A) and non-type 2 CRS group (group B) according to the patients' clinical ...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2018/6529283
更新日期:2018-05-17 00:00:00
abstract::Variations in human genome (e.g., single nucleotide polymorphisms, SNPs) may be associated with hereditary diseases, their complications, comorbidities, and drug responses. Using Web service SNP_TATA_Comparator presented in our previous paper, here we analyzed immediate surroundings of known SNP markers of diseases an...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/8642703
更新日期:2016-01-01 00:00:00
abstract::A bioenergetical analysis of swimming at intensities near competitive distances is inexistent. It was aimed to compare the transient VO2 kinetics responses and metabolic contributions whilst swimming at different velocities around VO2max. 12 trained male swimmers performed (i) an incremental protocol to determine the ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/675363
更新日期:2014-01-01 00:00:00
abstract:Objective:The exact shape of the dose-response relationship between maternal body mass index (BMI) and the risk of congenital heart defects (CHDs) in infants has not been clearly defined yet. This study aims to further clarify the relationship between maternal obesity and the risk of CHDs in infants by an overall and d...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2019/1315796
更新日期:2019-07-07 00:00:00
abstract::There is an emerging body of evidence that chemoresistance and minimal residual disease result from selective resistance of a cell subpopulation from the original tumor that is molecularly and phenotypically distinct. These cells are called "cancer stem cells" (CSCs). In this review, we analyze the potential targeting...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/859871
更新日期:2014-01-01 00:00:00
abstract::Novel and more effective treatment strategies against multiple myeloma (MM) have significantly prolonged patients' survival and raised interest in the depth of response and its association with clinical outcome. Minimal residual disease (MRD) has emerged as one of the most relevant prognostic factors in MM and should ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/832049
更新日期:2015-01-01 00:00:00
abstract:Background:Health workers are one of the most important building blocks of the health system. High turnover rate contribute to the shortfalls and unbalanced distribution of health personnel in the health workforce. Turnover intention is the strongest predictor of actual turnover. Objective:To assess the magnitude of t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3165379
更新日期:2018-12-23 00:00:00
abstract::Recent progress in microscopy technologies, biological markers, and automated processing methods is making possible the development of gene expression atlases at cellular-level resolution over whole embryos. Raw data on gene expression is usually very noisy. This noise comes from both experimental (technical/methodolo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/986436
更新日期:2015-01-01 00:00:00
abstract:Background:Musculoskeletal disorders (MSDs) are considered one of the most common health issues in working population and have a high social and economic impact. This study is aimed at determining the MSD patterns and associated risk factors among higher education academicians in Saudi Arabia. Methods:A cross-sectiona...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8930968
更新日期:2020-08-15 00:00:00
abstract::Sun Island Bund Wetland (SIBW) is a river floodplain wetland located at the south part of Heilongjiang Province in Northeast China. An investigation of the influence of habitat type on macroinvertebrates assemblages structure was conducted in July 2016. Nine (9) sampling sites were selected based on sediment type, wat...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/2650678
更新日期:2019-02-13 00:00:00
abstract::L-amino acid oxidases are enzymes found in several organisms, including venoms of snakes, where they contribute to the toxicity of ophidian envenomation. Their toxicity is primarily due to enzymatic activity, but other mechanisms have been proposed recently which require further investigation. L-amino acid oxidases ex...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/196754
更新日期:2014-01-01 00:00:00
abstract::Toll-like receptors (TLRs) play a key role in the innate immune response to numerous pathogens, including Acanthamoeba spp. The aim of this study was to determine the expression of TLR2 and TLR4 in the eyes of mice following intranasal infection with Acanthamoeba spp. in relation to the host's immunological status. Am...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/1401894
更新日期:2019-06-12 00:00:00
abstract:PURPOSE:The aim of this study is to describe the robotic assisted transfer device (RATD) and an initial focus group evaluation by end users. The purpose of the device is to aid in the transfers of people with disabilities to and from their electric powered wheelchair (EPW) onto other surfaces. The device can be used fo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/198476
更新日期:2015-01-01 00:00:00
abstract:Background:In addition to the widely known effect of vitamin D3 (vitD3) on the skeleton, its role in the regulation of the immune response was also confirmed. Aim:The assessment of biochemical and densitometric markers of calcium-phosphate metabolism in the groups of patients with relapsing-remitting multiple sclerosi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/9329123
更新日期:2018-08-23 00:00:00
abstract::The prospect of biomaterial hypersensitivity developing in response to joint implant materials was first presented more than 30 years ago. Many studies have established probable causation between first-generation metal-on-metal hip implants and hypersensitivity reactions. In a limited patient population, implant failu...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2015/137287
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of two foot placements (normal or posterior placement) and three arm positions (hands on the thighs, arms crossed over chest, and augmented arm position with elbow extended) on the five times sit-to-stand (FTSTS) test times of individuals with chronic stroke. DESIGN:Cross-sectional...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2014/636530
更新日期:2014-01-01 00:00:00
abstract::X-ray radiation resistance associated 1 (XRRA1) has been found to regulate the response of human tumor and normal cells to X-radiation (XR). Although XRRA1 overexpression is known to be involved in cancer cell response to XR, there are no reports about whether the expression of XRRA1 in tumors can adjust radioresistan...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/5718968
更新日期:2017-01-01 00:00:00
abstract::Pediatric myelodysplastic syndrome (MDS) is an uncommon disease and little is known about the molecular alterations of its development and evolution to acute myeloid leukemia (AML). The Enhancer of Zeste Homolog 2 (EZH2) is the catalytic subunit of Polycomb repressive complex 2 (PCR2). It is a histone methyltransferas...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1155/2019/3176565
更新日期:2019-12-10 00:00:00