NMR-based metabolomic analysis of spatial variation in soft corals.

Abstract:

:Soft corals are common marine organisms that inhabit tropical and subtropical oceans. They are shown to be rich source of secondary metabolites with biological activities. In this work, soft corals from two geographical locations were investigated using ¹H-NMR spectroscopy coupled with multivariate statistical analysis at the metabolic level. A partial least-squares discriminant analysis showed clear separation among extracts of soft corals grown in Sanya Bay and Weizhou Island. The specific markers that contributed to discrimination between soft corals in two origins belonged to terpenes, sterols and N-containing compounds. The satisfied precision of classification obtained indicates this approach using combined ¹H-NMR and chemometrics is effective to discriminate soft corals collected in different geographical locations. The results revealed that metabolites of soft corals evidently depended on living environmental condition, which would provide valuable information for further relevant coastal marine environment evaluation.

journal_name

Mar Drugs

journal_title

Marine drugs

authors

He Q,Sun R,Liu H,Geng Z,Chen D,Li Y,Han J,Lin W,Du S,Deng Z

doi

10.3390/md12041876

subject

Has Abstract

pub_date

2014-03-28 00:00:00

pages

1876-90

issue

4

issn

1660-3397

pii

md12041876

journal_volume

12

pub_type

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