Characterization of tumors produced by signal peptide-basic fibroblast growth factor-transformed cells.

abstract：:Stimulation of gonadotropin-releasing hormone (GnRH) receptors with the GnRH analogue buserelin enhances expression of the zinc finger transcription factor Egr-1 in a pituitary gonadotroph cell line. The signaling cascade is blocked by overexpression of MAP kinase phosphatase-1 that dephosphorylates extracellular sign...

journal_title：Journal of cellular biochemistry

authors： Mayer SI,Willars GB,Nishida E,Thiel G

更新日期：2008-12-01 00:00:00

abstract：:Glioblastoma is one of the most malignant cancers, with a distinguishing dismal prognosis: surgery followed by chemo- and radiotherapy represents the current standard of care, and chemo- and radioresistance underlie disease recurrence and short overall survival of patients suffering from this malignancy. ATM is a kina...

journal_title：Journal of cellular biochemistry

authors： Romano FJ,Guadagno E,Solari D,Borrelli G,Pignatiello S,Cappabianca P,Del Basso De Caro M

更新日期：2018-06-01 00:00:00

abstract：:Lipopolysaccharide (LPS) released from gram-negative bacteria stimulates immune responses in infected cells. Epigenetic modifications such as DNA methylation and protein methylation modulate LPS-induced innate immune gene expressions. Expression of the Klotho protein decreased with LPS treatment in rats. In a cellular...

journal_title：Journal of cellular biochemistry

authors： Tsai KD,Lee WX,Chen W,Chen BY,Chen KL,Hsiao TC,Wang SH,Lee YJ,Liang SY,Shieh JC,Lin TH

更新日期：2018-04-01 00:00:00

abstract：:Our previous study demonstrated that, stanniocalcin-1 (STC1) was a target of histone deacetylase (HDAC) inhibitors and was involved in trichostatin A (TSA) induced apoptosis in the human colon cancer cells, HT29. In this study, we reported that the transcriptional factor, specificity protein 1 (Sp1) in association wit...

journal_title：Journal of cellular biochemistry

authors： Law AY,Yeung BH,Ching LY,Wong CK

更新日期：2011-08-01 00:00:00

abstract：:The sex steroid hormones, androgens and estrogens, via their respective nuclear receptors, regulate bone mineral density in humans and mice. Very little is known about the direct targets of the androgen and estrogen receptors in bone cells. First, models of hormone and receptor deficiency in mouse and human bone are d...

journal_title：Journal of cellular biochemistry

authors： Krum SA

更新日期：2011-02-01 00:00:00

abstract：:Cervical cancer is among the most common type of cancers in women and is associated with human papillomavirus (HPV) infection. Genital warts are also reported to be linked with HPV infection types 11 and 6. In turn, clinical characteristics and morphological features of warts may be useful in the prediction of prognos...

journal_title：Journal of cellular biochemistry

authors： Hasanzadeh M,Rejali M,Mehramiz M,Akbari M,Mousavi Seresht L,Yazdandoost Y,Farokhi S,Mahdian Z,Maleki F,Emamdadi-Aliabad Z,Jalilvand N,Khorrami S,Fadaei Z,Movahedi M,Hosseini Z,Razmi F,Takamoli T,Ferns GA,Avan A

更新日期：2019-08-01 00:00:00

abstract：:Androgen-regulated genes (ARG) are implicated in normal and neoplastic growth of the prostate. Recently, we reported genomic amplification and/or overexpression of a previously known neurotrophic factor, prosaposin, in androgen-independent (AI) or metastatic prostate cancer (PCa) cells and tissues. Prosaposin and/or i...

journal_title：Journal of cellular biochemistry

authors： Koochekpour S,Lee TJ,Wang R,Sun Y,Delorme N,Hiraiwa M,Grabowski GA,Culig Z,Minokadeh A

更新日期：2007-06-01 00:00:00

abstract：:The human undifferentiated histiocytic cell-line U937 can be induced to differentiate by incubation with 12-0-tetradecanoylphorbol-13-acetate (TPA) into macrophage-like cells. Dexamethasone reduced the prostaglandin production in TPA-differentiated U937 cells dose dependently, whereas undifferentiated U937 cells were ...

journal_title：Journal of cellular biochemistry

authors： Koehler L,Hass R,Goppelt-Struebe M,Kaever V,Resch K

更新日期：1989-07-01 00:00:00

abstract：:A panel of monoclonal antibodies and conventional antisera directed against desmosomal proteins from bovine muzzle epidermis was used to identify immunologically related proteins from two other bovine stratified squamous epithelia, cornea and esophagus. Desmosome-enriched tissue fractions were prepared from epidermis,...

journal_title：Journal of cellular biochemistry

authors： Giudice GJ,Cohen SM,Patel NH,Steinberg MS

更新日期：1984-01-01 00:00:00

abstract：:Inflammation in vascular (mostly arterial) walls and heart valves triggered by the trans-endothelial influx of LDL particles and the action of subsequently modified (e.g., by oxidation) LDL particles can trigger true bone formation by valvar fibroblasts, by a subpopulation of re-differentiation-competent VSMCs (vascul...

journal_title：Journal of cellular biochemistry

authors： Whitfield JF

更新日期：2005-06-01 00:00:00

abstract：:Our study was aimed to investigate the mechanism of rs4759314 located in HOTAIR involved in congenital heart disease. Luciferase assay was performed to evaluate whether rs4759314 affected the transcription efficiency of HOTAIR promoter, and confirm miR-545 target gene. Real-time PCR, Western-blot and IHC were carried ...

journal_title：Journal of cellular biochemistry

authors： Li Y,Zhao W,Shi R,Jia J,Li X,Cheng J

更新日期：2018-11-01 00:00:00

abstract：:We provided evidence that calcium-calmodulin plays a major role in bradykinin-induced arachidonic acid release by bovine aortic endothelial cells. In cells labeled for 16 hr with 3H-arachidonic acid, ionomycin and Ca2(+)-mobilizing hormones such as bradykinin, thrombin and platelet activating factor induced arachidoni...

journal_title：Journal of cellular biochemistry

authors： Briand SI,Bernier SG,Guillemette G

更新日期：1996-12-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-alpha) mediated attenuation of insulin signaling pathway is an important cause in several disorders like obesity, obesity linked diabetes mellitus. TNF-alpha actions vary depending upon concentration and time of exposure in various cells. In the present study, the effects of long-term ...

journal_title：Journal of cellular biochemistry

authors： Gupta D,Varma S,Khandelwal RL

更新日期：2007-02-15 00:00:00

abstract：:We characterized a human cDNA clone encoding a 36-kDa carboxyl terminal LIM domain protein with a PDZ domain at the amino terminal. This full-length cDNA clone has a predicted open reading frame (ORF) of 329 amino-acid residues. The ORF of this cDNA encodes the human homolog of rat CLP36, and the putative protein is n...

journal_title：Journal of cellular biochemistry

authors： Kotaka M,Ngai SM,Garcia-Barcelo M,Tsui SK,Fung KP,Lee CY,Waye MM

更新日期：1999-02-01 00:00:00

abstract：:In a previous work, taking advantage of the gene-array screening technology, we analysed the effects of histone deacetylase (HDAC) inhibitor sodium butyrate (NaBt), on gene transcription in HT29 human adenocarcinoma cell line. In this study, we focused our attention on p55CDC/Cdc20 gene, whose expression was dramatica...

journal_title：Journal of cellular biochemistry

authors： Iacomino G,Medici MC,Napoli D,Russo GL

更新日期：2006-11-01 00:00:00

abstract：:The role of TatD DNases as DNA repair enzymes or cell death (apoptotic) nucleases is well established in prokaryotes as well as eukaryotes. The current study aims to characterize the TatD nuclease from Bacillus anthracis (Ba TatD) and to explore its key histidine catalytic residues. Ba TatD was found to be a metal-dep...

journal_title：Journal of cellular biochemistry

authors： Singh D,Rahi A,Kumari R,Gupta V,Gautam G,Aggarwal S,Rehan M,Bhatnagar R

更新日期：2019-02-05 00:00:00

abstract：:3-Acetyl-11-keto-β-boswellic acid (AKBA), a pentacyclic triterpenic acid present in gum resin of Boswellia serrata, has been found to possess antioxidant and neuroprotective properties. In this study, we aimed to examine protective properties of AKBA against glutamate-induced neuronal injury. To investigate the effect...

journal_title：Journal of cellular biochemistry

authors： Rajabian A,Sadeghnia HR,Hosseini A,Mousavi SH,Boroushaki MT

更新日期：2020-02-01 00:00:00

abstract：:Membrane vesicles were prepared by incubation of human erythrocytes with dimyristoylphosphatidylcholine [3] and isolated by isopycnic centrifugation on Dextran density gradients. Protein analyses were carried out with crossed immunoelectrophoresis and dodecylsulfate polyacrylamide gel electrophoresis. The right-side-o...

journal_title：Journal of cellular biochemistry

authors： Weitz M,Bjerrum OJ,Ott P,Brodbeck U

更新日期：1982-01-01 00:00:00

abstract：:Avian influenza viruses (AIV) are very active in several parts of the globe and are the cause of huge economic loss for the poultry industry and also human fatalities. Three dimensional modeling was carried out for neuraminidase (NA) and hemagglutinin (HA) proteins of AIV. The C-score, estimated TM-Score, and estimate...

journal_title：Journal of cellular biochemistry

authors： Ramamurthy M,Sankar S,Abraham AM,Nandagopal B,Sridharan G

更新日期：2019-10-01 00:00:00

abstract：:Ischemia/reperfusion injury is a tissue injury occurring post-reperfusion of tissues with pre-existing ischemia. A good blood supply to tissues aids in the survival of ischemic tissue, however, due to prolonged ischemia the levels of ATP decrease and pH declines leading to acidosis. Reduced ATP leads to an increase in...

journal_title：Journal of cellular biochemistry

authors： Ghaderi S,Alidadiani N,SoleimaniRad J,Heidari HR,Dilaver N,Heim C,Ramsperger-Gleixner M,Baradaran B,Weyand M

更新日期：2018-09-01 00:00:00

abstract：:The type 2 diabetes is one of the major global health issues that affects millions of people. This study evaluated the antidiabetic activity of aqueous extracts (AECP) and methanol extracts (MECP) from Ceiba pentandra trunk bark on an experimental model of type 2 diabetes (T2D). This model was induced in rats by the c...

journal_title：Journal of cellular biochemistry

authors： Fofie CK,Katekhaye S,Borse S,Sharma V,Nivsarkar M,Nguelefack-Mbuyo EP,Kamanyi A,Singh V,Nguelefack TB

更新日期：2019-02-14 00:00:00

abstract：:In addition to cholesterol-lowering effect, HMG-CoA reductase inhibition by statins has been shown to have protective effect in many cells type. The loss of vision in retinal degeneration disease associates with oxidative stress and apoptosis in retinal pigment epithelium (RPE) cell. This study was designed to examine...

journal_title：Journal of cellular biochemistry

authors： Qian J,Keyes KT,Long B,Chen G,Ye Y

更新日期：2011-09-01 00:00:00

abstract：:Inoculations with antigen-expressing plasmid DNAs (DNA vaccines) in the production of protective immune responses. Since the initial development of DNA vaccines more than 5 years ago, major strides have been made in the design of efficient vaccine vectors and in the process of vaccine delivery. However, many questions...

journal_title：Journal of cellular biochemistry

authors： Feltquate DM

更新日期：1998-01-01 00:00:00

abstract：:The influence of concentration of simvastatin (SIM) on free radicals in A-2058 human melanoma malignum cells was studied. The proliferation assay for melanoma A-2058 cells with SIM in concentration range from 0.1 to 20 µM was performed. SIM in the concentrations of 0.1, 0.3, and 1 μM only slightly changed the growth o...

journal_title：Journal of cellular biochemistry

authors： Zdybel M,Chodurek E,Pilawa B

更新日期：2018-09-11 00:00:00

abstract：:Compound C, a well-known inhibitor of AMP-activated protein kinase (AMPK), has been reported to exert antitumor activities in some types of cells. Whether compound C can exert antitumor effects in human cholangiocarcinoma (CCA) remains unknown. Here, we demonstrated that compound C is a potent inducer of cell death an...

journal_title：Journal of cellular biochemistry

authors： Zhao X,Luo G,Cheng Y,Yu W,Chen R,Xiao B,Xiang Y,Feng C,Fu W,Duan C,Yao F,Xia X,Tao Q,Wei M,Dai R

更新日期：2018-07-01 00:00:00

abstract：:Fourteen stable subclones derived from the murine chondrogenic cell line MC615 were established and characterised regarding their differentiation stages and responsivity to BMP2. Based on their gene expression profiles which revealed remarkable variances in Col2a1 and Col10a1 expression, subclones could be grouped int...

journal_title：Journal of cellular biochemistry

authors： Surmann-Schmitt C,Widmann N,Mallein-Gerin F,von der Mark K,Stock M

更新日期：2009-10-15 00:00:00

abstract：:The receptor for epidermal growth factor (EGF) is a glycosylated transmembrane phosphoprotein that exhibits EGF-stimulable protein tyrosine kinase activity. On EGF stimulation, the receptor undergoes a self-phosphorylation reaction at tyrosine residues located primarily in the extreme carboxyl-terminal region of the p...

journal_title：Journal of cellular biochemistry

authors： Bertics PJ,Weber W,Cochet C,Gill GN

更新日期：1985-01-01 00:00:00

abstract：:Cathepsin K (CatK) is a lysosomal cysteine protease necessary for bone resorption by osteoclasts (OCs), which originate from myeloid hematopoietic precursors. CatK-deficient (CatK(-/-) ) mice show osteopetrosis due to defective resorption by OCs, which are increased in number in these mice. We investigated whether gen...

journal_title：Journal of cellular biochemistry

authors： Jacome-Galarza C,Soung do Y,Adapala NS,Pickarski M,Sanjay A,Duong LT,Lorenzo JA,Drissi H

更新日期：2014-08-01 00:00:00

abstract：:The bcl-2 gene has a unique function among mammalian oncogenes as a negative regulator of apoptosis. Its expression pattern in embryonic and adult tissues is consistent with a role in maintaining in vivo survival of specific cell types. The biochemical function of bcl-2 is unknown, but its localization to mitochondria...

journal_title：Journal of cellular biochemistry

authors： Park JR,Hockenbery DM

更新日期：1996-01-01 00:00:00

abstract：:The objective of this study was to test the hypothesis that extracellular matrix (ECM) would alter the endoplasmic reticulum (ER) stress response of chondrocytes. Chondrocytes were isolated from calf knees and maintained in monolayer culture or suspended in collagen I to form spot cultures (SCs). Our laboratory has sh...

journal_title：Journal of cellular biochemistry

authors： Nugent AE,McBurney DL,Horton WE Jr

更新日期：2011-04-01 00:00:00