Abstract:
OBJECTIVE:To put forth new findings of urologic oncology with impact on clinical practice presented during 2017 in the main annual meetings. METHODS:This document reviews abstracts on prostate, kidney and bladder cancer presented at the congresses of 2016 (EAU, AUA, ASCO, ESMO and ASTRO) and publications with the highest impact in this period valued with the highest scores by the OncoForum committee. RESULTS:Among patients at high risk of recurrent renal cell carcinoma after nephrectomy, adjuvant sunitinib compared to placebo showed a benefit in patients at higher risk of recurrence. In cisplatin-ineligible advanced urothelial cancer, pembrolizumab elicits clinically meaningful, durable responses. Among patients with localized prostate cancer, treatment for disease progression was less frequent (absolute difference, 26.2 percentage pontis) and adverse events was more frequent with surgery than with observation. Among patients with locally advanced or merastatic prostate cancer, androgen-deprivation therapy plus abiraterone and prednisolone resulted in fewer deaths and fewer treatment-failure events (P<.001). Among patients with metastatic castration-resistant prostate cancer previously treated with abiraterone acetate, enzalutamide median radiographic progression free survival was 8,1 months and enzalutamide median overall survival was not reached. CONCLUSIONS:Among patients at high risk of recurrent renal cell carcinoma after nephrectomy, adjuvant sunitinib showed a benefit across subgroups including patients at higher risk of recurrence. Among patients with localized prostate cancer, surgery was not associated with significantly lower all-cause or porstate-cancer mortality than observation. Among patients with locally advanced or merastatic prostate cancer, androgen-deprivation therapy plus abiraterone and prednisolone was associated with significantly higher rates of overall and failure-free survival than androgen-deprivation therapy alone. In patients with metastatic castration-resistant prostate cancer previously treated with abiraterone enzalutamide remained active.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Gómez-Veiga F,Alcaraz-Asensio A,Burgos-Revilla J,Cózar-Olmo Jdoi
10.1016/j.acuro.2018.06.001subject
Has Abstractpub_date
2018-10-01 00:00:00pages
488-498issue
8eissn
0210-4806issn
1699-7980pii
S0210-4806(18)30110-4journal_volume
42pub_type
杂志文章,评审abstract::Patient suffering from vesical carcinoma, which is identified as small cells (oat cells) carcinoma. We carried out a histochemical study with H.C.G. and C.E.A. and analyse the results obtained. ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::Presentation of one case of soft lithiasis in a child which was treated by pyelolithectomy with good results and which has not relapsed after a 20-year follow-up. A commented revision is made of related literature. ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1994-05-01 00:00:00
abstract::Laparoscopic surgery is a surgical technique the urologist should add to his surgical armamentarium. Its performance tries to mimic the surgical phases of open surgery, and also its indications. Laparoscopic partial nephrectomy is a sophisticated technique that requires wide experience in the performance of endoscopic...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(06)73486-6
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:To analyse the value of a second transurethral resection, repeated within 3 to 6 weeks after the initial resection, in the treatment and the classification of patients with bladder tumour. MATERIAL AND METHODS:We analyse the results of 72 repeated transurethral resection in 23 (32%) patients with T1 G1-2 bla...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(01)72596-x
更新日期:2001-03-01 00:00:00
abstract:INTRODUCTION:The prognosis of patients diagnosed with metastatic prostate cancer seems to be modulated by factors such as the number and site of metastases. Our objective is to evaluate survival outcomes according to the number and site of metastases in our series of metastatic patients over the last 15 years. MATERIA...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2016.09.004
更新日期:2017-05-01 00:00:00
abstract::Anatomical and physiological changes in the urinary tract develop during pregnancy. These changes may affect the urinary outflow. Urinary symptoms may develop during pregnancy in previously asymptomatic patients. Most of these symptoms will vanish after delivery. Some of them remain and others will become worse in con...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(99)72367-3
更新日期:1999-10-01 00:00:00
abstract::Case of an 83 year-old male with metastatic penis cancer located at the glans, secondary to moderately differentiated prostatic adenocarcinoma. There was early metastasis clinically expressed as several painful and ulcerous nodes at the glans corona and paraphimosis. The clinical rareness of metastasis in a porous bod...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1991-05-01 00:00:00
abstract:INTRODUCTION:There is a need for a precise and reliable imaging to improve the management of prostate cancer. In recent years the PET/CT with choline has changed the handling of prostate cancer in Europe, and it is commonly used for initial stratification or for the diagnosis of a biochemical recurrence, although it do...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/j.acuro.2016.09.015
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to know if the use of oral Tegafur associated to intravesical mitomycin is effective in the prevention of the relapses of Ta bladder tumors. METHOD:This is a prospective study in which we compare the recurrence rate and the disease-free interval of 2 groups of 40 patients each one, t...
journal_title:Actas urologicas espanolas
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0210-4806(03)72950-7
更新日期:2003-06-01 00:00:00
abstract::During the first ten years (1981-1990) of our organ transplantation program a total of 395 Renal Transplants (RTx) have been carried out in our Unit, 90 of which in 88 patients had to be subsequently transplantectomized. In 32 of them the reason was acute rejection (35%) including 7 renal rhexis, and in 30 chronic rej...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Urethral duplication is a rare congenital anomaly affecting mainly males and being usually diagnosed during paedriatric age. We report a 20 year old male complaining of double urethral meatus with double urinary stream. Physical examination confirmed and additional hypospadic meatus below a normally placed urethral me...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(05)73204-6
更新日期:2005-01-01 00:00:00
abstract:RATIONALE:Analysis of complications resulting from the renal percutaneous approach. METHODS:Between 1990 and 1996, 175 percutaneous surgical procedures were performed by our group. In 69.2% cases, the reason was a lithiasic condition. We also carried out: 35 endopyelotomies, 12 renal cyst resections, 4 stenosis of ure...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1998-02-01 00:00:00
abstract::Fifty-one patients with non-seminoma testicular cancer who underwent retroperitoneal ganglion dissection and 3 support cycles of chemotherapy with Cys-Platin, Vinblastine and Bleomycin. Four patients presented relapses (7.8%). Actuarial survival by 8 years was 87%, with a median of 38 months. The median survival was 4...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:INTRODUCTION:Cognitive training is an important training modality which allows the user to rehearse a procedure without physically carrying it out. This has led to recent interests to incorporate cognitive training within surgical education but research is currently limited. The use of cognitive training in surgery is ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.acuro.2017.06.008
更新日期:2018-04-01 00:00:00
abstract::The influence of renal and hepatic functioning on serum levels of prostate specific antigen has been studied by examining its behaviour in a control group (CG) of 178 healthy male, a group of 48 patients with end-stage renal failure (ESRF) 22 of which had pre- and post-dialysis PSA measurements and a group of 48 patie...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract:OBJECTIVE:Non-heartbeating donors (NHBD) are an alternative to heartbeating donors (HBD). Our objective was to compare functional results and kidney survival from NHBDs and HBDs. MATERIAL AND METHODS:A retrospective study comparing the results of 236 normothermically preserved kidneys from type i and ii type NHBDs wit...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2015.01.005
更新日期:2015-09-01 00:00:00
abstract::Primary vesical adenocarcinoma is an extremely uncommon tumour, representing 0.5 to 2% of all the urothelial vesical neoplasias. Its behaviour is aggressive and its prognosis poor, especially in the seal ring cell variety. We present our experience in seven cases of vesical adenocarcinoma: one of urachal origin, two o...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract:CONTEXT:The objective of evidence-based medicine is to employ the best scientific information available to apply to clinical practice. Understanding and interpreting the scientific evidence involves understanding the available levels of evidence, where systematic reviews and meta-analyses of clinical trials are at the ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2018.01.010
更新日期:2018-10-01 00:00:00
abstract:CONTEXT:Cervical cancer is the second most common tumor in women worldwide and due to diagnostic and therapeutic advances, the overall survival rates at 5 years is approaching 70%. Disorders in micturition, defecation, sexuality and quality of life have been described, frequently caused by different treatments. Address...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/j.acuro.2012.03.008
更新日期:2013-01-01 00:00:00
abstract::The coincidence of an urachal adenocarcinoma with another similar tumour in other location makes necessary to separate a true primary from a metastatic adenocarcinoma. We report the case of a 66-years-old-man with an urachal mucinous adenocarcinoma and two colonic adenocarcinoma excised in the same surgical act, showi...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVE:To analyze the expression of metalloprotein 11 (MMP11) in cultured fibroblasts obtained from human prostate tumors with different clinical and pathological characteristics. MATERIAL AND METHODS:For this study we analyzed samples of transrectal prostate biopsies from tumors with different characteristics, tre...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2016.12.001
更新日期:2017-01-01 00:00:00
abstract::Primary prostate transitional cell carcinoma is a very uncommon tumor, that represents about 1% of all prostate tumours. In our institution, only six patients have been diagnosed with pure transitional cell prostate carcinoma until 2002. Bladder origin of the neplasic was ruled out in all cases. We report a study abou...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(04)73092-2
更新日期:2004-05-01 00:00:00
abstract::Report on the presence in 43 patients of various foreign materials left in the urinary tract following a surgical procedure. The clinical symptoms exhibited by these patients correspond to a urinary syndrome with irritation or lumbar pain when the foreign body blocked the upper urinary tract. In most cases, diagnosis ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1991-09-01 00:00:00
abstract::Inguinoscrotal bladder hernias are uncommon clinical facts more predominant in males aged between 50 and 70. This entity has no specific clinical character and diagnosis usually happens in the course of surgical repair of inguinal hernia. In about 3%-10% cases, it appears associated to inguinal hernia. Discussion of t...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract:INTRODUCTION:Umbilical laparoendoscopic single-site (LESS) surgery represents an excellent alternative to laparoscopic or robotic multiport surgery. LESS surgery offers faster recovery, less postoperative pain and optimal cosmetic results. LESS is possible in virtually any urologic surgery. PATIENT AND METHOD:We prese...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2014.07.004
更新日期:2015-05-01 00:00:00
abstract:UNLABELLED:Caliceal diverticula may be congenital or acquired malformations of the collecting system, normally asymptomatic and discovered during an IVP. Indications for treatment included chronic vague flank pain, acute renal colic, urinary tract infection and hematuria. We present the results of 29 patients with symp...
journal_title:Actas urologicas espanolas
pub_type: 临床试验,杂志文章,评审
doi:
更新日期:1998-10-01 00:00:00
abstract::Orbital metastasis is an unusual localization within tumoral dissemination of prostatic cancer. Similarly, it is rare that orbital metastasis might be responsible for the clinic manifestations that determine the initial diagnosis of neoplasia. We illustrate the case of a patient suffering from prostatic adernocarcinom...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(03)72974-x
更新日期:2003-07-01 00:00:00
abstract::We present two cases in which during retropubic prostatectomy for benign prostatic disease a prostatorectal fistula ocurred. We describe its reparation using a pedicled flap of gracilis muscle. We also present cystographic and opaque enema images which shows the before and after of this surgery. Patients had good outc...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(04)73113-7
更新日期:2004-06-01 00:00:00
abstract::Fournier's gangrene (FG) is a rare and potentially fatal infectious disease characterised by necrotic fasciitis of the perineum and abdominal wall in addition to the scrotum and penis in men and the vulva in women. Skin loss can be very damaging and difficult to repair. This condition must be treated aggressively. Sev...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(09)72884-0
更新日期:2009-09-01 00:00:00
abstract::The germinal bilateral tumor represents from 1 to 4% of the testicle tumors, and it usually turns to be one of the most difficult ones when talking about diagnosis and treatment. We are attaching a 30 years old patient case, with a diagnosis consisting in a seminoma with yolk sac tumor area from the left testicle, tha...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:2003-02-01 00:00:00