Alternative oxidase inhibitors as antiparasitic agents against scuticociliatosis.

abstract：:Sequence comparisons have recently shown that the Schistosoma mansoni protein Sm32 is similar to asparaginyl endoproteinases, a novel family of cysteine proteinases, of which the legumains from legumes are the best characterized. By synthesizing and employing fluorogenic peptide substrates for the specific detection o...

journal_title：Parasitology

authors： Dalton JP,Hola-Jamriska L,Brindley PJ

更新日期：1995-12-01 00:00:00

abstract：:Epidemiological rate parameters of host generalist parasites are difficult to estimate, especially in cases where variation in parasite performance can be attributed to host species. Such cases are likely common for generalist parasites of sympatric grazing mammals. In this study, we combined data from experimental ex...

journal_title：Parasitology

authors： Beck MA,Goater CP,Colwell DD

更新日期：2015-09-01 00:00:00

abstract：:Theileria-free waterbuck (Kobus defassa) born in captivity were successfully infected with Theileria parva sporozoites derived from ticks infected by feeding on African buffalo (Syncerus caffer). All waterbuck underwent mild infections with the development of sporadic schizont and piroplasm parasitosis when inoculated...

journal_title：Parasitology

authors： Stagg DA,Bishop RP,Morzaria SP,Shaw MK,Wesonga D,Orinda GO,Grootenhuis JG,Molyneux DH,Young AS

更新日期：1994-06-01 00:00:00

abstract：:SSU ribosomal sequences of trypanosomes from Brazilian cattle and water buffalo were used to infer phylogenetic relationships between non-pathogenic T. theileri and allied species parasitic in artiodactyls. T. theileri trypanosomes from distinct geographical regions in Brazil and from other countries were tightly clus...

journal_title：Parasitology

authors： Rodrigues AC,Paiva F,Campaner M,Stevens JR,Noyes HA,Teixeira MM

更新日期：2006-02-01 00:00:00

abstract：:Vertically transmitted parasites (VTPs) such as Wolbachia are expected not only to minimize the damage they inflict on their hosts, but also to protect their hosts against the damaging effects of coinfecting parasites. By modifying the fitness costs of the infection, VTPs can therefore play an important role in the ev...

journal_title：Parasitology

authors： Zélé F,Denoyelle J,Duron O,Rivero A

更新日期：2018-05-01 00:00:00

abstract：:Levamisole (Lms) is an anthelminthic drug with immunomodulatory activity. Chagas disease (CD) is caused by Trypanosoma cruzi and there is very low access to the drugs available, benznidazole (Bz) and nifurtimox, both far from ideal. In a drug-repurposing strategy to test potential activity as antiparasitic and immunom...

journal_title：Parasitology

authors： Rocha Simões-Silva M,Brandão Peres R,Britto C,Machado Cascabulho C,de Melo Oliveira G,Nefertiti da Gama A,França da Silva C,Lima da Costa K,Finamore Araújo P,Diego de Souza Campos J,Meuser Batista M,Cristina Demarque K,da Cruz Mo

更新日期：2019-07-01 00:00:00

abstract：:The molecular phylogeny and morphology of the oxyuroid nematode genus Aspiculuris from voles and house mice has been examined. Worms collected from Myodes glareolus in Poland, Eire and the UK are identified as Aspiculuris tianjinensis, previously known only from China, while worms from Mus musculus from a range of loc...

journal_title：Parasitology

authors： Behnke JM,Stewart A,Bajer A,Grzybek M,Harris PD,Lowe A,Ribas A,Smales L,Vandegrift KJ

更新日期：2015-10-01 00:00:00

abstract：:A one-year study of gastro-intestinal parasitism in a free-ranging population of maras at Whipsnade Wild Animal Park, UK, revealed a strong relationship between membership of social units and both intensity and prevalence of infection. The mara, a hystricomorph rodent from southern Argentina, has a social organization...

journal_title：Parasitology

authors： Porteous IS,Pankhurst SJ

更新日期：1998-03-01 00:00:00

abstract：:Ticks have numerous natural enemies, but only a few species have been evaluated as tick biocontrol agents (BCAs). Some laboratory results suggest that several bacteria are pathogenic to ticks, but their mode of action and their potential value as biocontrol agents remain to be determined. The most promising entomopath...

journal_title：Parasitology

authors： Samish M,Ginsberg H,Glazer I

更新日期：2004-01-01 00:00:00

abstract：:The community structure of monogeneans on the gills of a catfish Pimelodus albicans, in the Río de la Plata, was studied and compared with previous findings on P. maulatus. Six Monogenea species belonging to 3 genera were found: Demidospermus majusculus Kritsky & Gutiérrez, 1998; Demidospermus armostus Kritsky & Gutié...

journal_title：Parasitology

authors： Gutiérrez PA

更新日期：2001-04-01 00:00:00

abstract：:Of the 7 genetic assemblages of the parasite Giardia duodenalis only 2 (A and B) are known to cause infections in humans. These assemblages have been characterized in detail at the genomic level but few studies have examined differences in the proteins expressed. Employing one and two-dimensional PAGE we have identifi...

journal_title：Parasitology

authors： Steuart RF,O'Handley R,Lipscombe RJ,Lock RA,Thompson RC

更新日期：2008-12-01 00:00:00

abstract：:The impact of immunization with gentamicin-attenuated Leishmania infantum (H-line) on the immunophenotypic profile of popliteal lymph node (PLN) and peripheral blood mononuclear cells (PBMCs) of dogs was assessed by flow cytometry and immunohistochemistry. Compared with the dogs infected with L. infantum wild-type (Gr...

journal_title：Parasitology

authors： Daneshvar H,Sedghy F,Dabiri S,Kamiabi H,Molaei MM,Phillips S,Burchmore R

更新日期：2012-11-01 00:00:00

abstract：:Life-cycle stages of the microsporidia Nosema bombycis, the pathogen causing silkworm pebrine, were separated and purified by an improved method of Percoll-gradient centrifugation. Soluble protein fractions of late sporoblasts (spore precursor cells) and mature spores were analysed by two-dimensional polyacrylamide ge...

journal_title：Parasitology

authors： Cai S,Lu X,Qiu H,Li M,Feng Z

更新日期：2011-08-01 00:00:00

abstract：:The outcome of a parasite infection is the result of the interaction between the host and the parasite. In the system we studied, there are 3 critical stages for the outcome of infection of the (intermediate) host, the copepod Macrocyclops albidus, with the cestode Schistocephalus solidus. During the establishment pha...

journal_title：Parasitology

authors： van der Veen IT,Kurtz J

更新日期：2002-04-01 00:00:00

abstract：:Endotoxaemia has been described in cases of Human African trypanosomiasis (HAT), but it is unclear if this phenomenon influences inflammatory pathology either in the periphery or central nervous system (CNS). We studied endotoxin concentrations in the plasma and cerebrospinal fluid (CSF) of Trypanosoma brucei rhodesie...

journal_title：Parasitology

authors： Maclean L,Aboubaker EA,Kennedy PG,Sternberg JM

更新日期：2017-04-01 00:00:00

abstract：:In previous studies, ultrastructural observations revealed a large number of gap junctions (GJs) in the neck and immature proglottid tissues of Taenia solium tapeworms. In these helminths, cytoplasmic glycogen sacs are connected by numerous discrete GJs to other cells throughout the maturing strobilar tissue. Disconti...

journal_title：Parasitology

authors： Zurabian R,Landa A,Robert L,Willms K

更新日期：2008-08-01 00:00:00

abstract：:During the early stages of the primary Plasmodium chabaudi chabaudi AS parasitaemia in CBA/Ca mice this parasite invaded normocytes, but as the parasitaemia developed increasing numbers of parasites were seen within reticulocytes. During and just after peak parasitaemia, as further parasite replication was controlled,...

journal_title：Parasitology

authors： Jarra W,Brown KN

更新日期：1989-10-01 00:00:00

abstract：:The 'Muguga cocktail' live vaccine, delivered by an infection and treatment protocol, has been widely deployed in Eastern, Central and Southern Africa to protect cattle against East Coast fever, caused by Theileria parva. The vaccine contains 3 component stocks (Muguga, Serengeti-transformed and Kiambu 5). In a previo...

journal_title：Parasitology

authors： Oura CA,Bishop R,Asiimwe BB,Spooner P,Lubega GW,Tait A

更新日期：2007-08-01 00:00:00

abstract：:Alveolar echinococcosis (AE) is a zoonotic parasitic diseases caused by a cestode parasite known as Echinococcus multilocularis. The parasite has a wildlife cycle with definitive hosts (foxes) and small mammals as intermediate hosts (rodents) while humans are the accidental hosts. Parasite infection pressure relation ...

journal_title：Parasitology

authors： Khan A,Ahmed H,Sohail A,Alam F,Simsek S

更新日期：2020-03-01 00:00:00

abstract：:Infection of small macropodids with the larval stage of Echinococcus granulosus can cause fatalities as well as significant pulmonary impairment and other adverse sequelae. The brush-tailed rock-wallaby (Petrogale penicillata) is a small macropodid listed as vulnerable on the IUCN's Red List of Threatened Species. Thi...

journal_title：Parasitology

authors： Barnes TS,Goldizen AW,Morton JM,Coleman GT

更新日期：2008-05-01 00:00:00

abstract：:A procedure is described for the isolation of sub-cellular fractions from bloodstream forms of Trypanosoma brucei. The method leaves intact most of the nuclei, mitochondria and microbodies. All the fractions have been chemically characterized and tested for 10 enzymatic markers. About 5% of total cell protein was isol...

journal_title：Parasitology

authors： Rovis L,Baekkeskov S

更新日期：1980-06-01 00:00:00

abstract：:Blood examination by microhaematocrit and haemoculture of 459 snakes belonging to 37 species revealed 2.4% trypanosome prevalence in species of Viperidae (Crotalus durissus and Bothrops jararaca) and Colubridae (Pseudoboa nigra). Trypanosome cultures from C. durissus and P. nigra were behaviourally and morphologically...

journal_title：Parasitology

authors： Viola LB,Campaner M,Takata CS,Ferreira RC,Rodrigues AC,Freitas RA,Duarte MR,Grego KF,Barrett TV,Camargo EP,Teixeira MM

更新日期：2008-04-01 00:00:00

abstract：:High levels of molecular diversity were identified in mitochondrial cytochrome c oxidase (cox1) gene sequences of Schistosoma turkestanicum from Hungary. These cox1 sequences were all specific to Hungary which contrasted with the low levels of diversity seen in the nuclear internal transcribed spacer region (ITS) sequ...

journal_title：Parasitology

authors： Lawton SP,Bowen LI,Emery AM,Majoros G

更新日期：2017-11-01 00:00:00

abstract：:Avian malaria is a mosquito-borne disease caused by Plasmodium spp. protozoa. Although these parasites have been extensively studied in North America and Eurasia, knowledge on the diversity of Plasmodium, its vectors and avian hosts in Africa is scarce. In this study, we report on natural malarial infections in free-r...

journal_title：Parasitology

authors： Aly MZY,Mohamed III,Sebak SI,Vanstreels RET,El Gendy AM

更新日期：2020-08-01 00:00:00

abstract：:The host recognition and invasion process of Myxobolus cerebralis actinospores (triactinomyxon, TAM) was studied on a genetic level. A small-scale in vitro assay was developed to activate a large number of TAMs simultaneously, and to monitor the host invasion in the absence of live fish. The transcriptomes of non-acti...

journal_title：Parasitology

authors： Eszterbauer E,Kallert DM,Grabner D,El-Matbouli M

更新日期：2009-04-01 00:00:00

abstract：:Infections with Haemonchus contortus are a major constraint on ruminant health world-wide. Young lambs are very sensitive to Haemonchus infection. Older lambs and sheep acquire immunity after a continuous or seasonal exposure to the parasite. The mechanisms underlying immunity are still not completely understood. Anti...

journal_title：Parasitology

authors： Schallig HD

更新日期：2000-01-01 00:00:00

abstract：:Leishmania are obligatory intracellular parasitic protozoa that cycle between sand fly mid-gut and phagolysosomes of mammalian macrophages. They have developed genetically programmed changes in gene and protein expression that enable rapid optimization of cell function according to vector and host environments. During...

journal_title：Parasitology

authors： Tsigankov P,Gherardini PF,Helmer-Citterich M,Zilberstein D

更新日期：2012-08-01 00:00:00

abstract：:Exponential decay in community similarity as a function of distance is a ubiquitous phenomenon in biogeography. Thus, for parasite communities, pairwise similarity decreases with increasing geographical distance between host populations. This biogeographical rule should also apply along other dimensions characterizing...

journal_title：Parasitology

authors： Poulin R

更新日期：2010-04-01 00:00:00

abstract：:A thymine-uracil transport system is present in the plasma membrane brush-border of the tapeworm, Hymenolepis diminuta. The relation between initial uptake and substrate concentration of either thymine or uracil was sigmoidal when 2-14C-labelled substrates were used. In contrast, absorption kinetics of methyl-14C- and...

journal_title：Parasitology

authors： Uglem GL,Dupre RK,Harley JP

更新日期：1983-10-01 00:00:00

abstract：:We assessed the distribution of Trypanosoma cruzi Discrete Typing Units (DTUs) in domestic and peridomestic Triatoma infestans and Triatoma sordida specimens collected in a well-defined rural area in Pampa del Indio, northeastern Argentina. Microscopically-positive bugs were randomly selected with a multi-level sampli...

journal_title：Parasitology

authors： Maffey L,Cardinal MV,Ordóñez-Krasnowski PC,Lanati LA,Lauricella MA,Schijman AG,Gürtler RE

更新日期：2012-10-01 00:00:00