Fortification of human milk in very low birth weight infants (VLBW

abstract：:The lifespan risk of seizures is highest in the neonatal period. Current therapies have limited efficacy. Although the treatment of neonatal seizures has not changed significantly in the last several decades, there has been substantial progress in understanding developmental mechanisms that influence seizure generatio...

journal_title：Clinics in perinatology

authors： Jensen FE

更新日期：2009-12-01 00:00:00

abstract：:To understand medical disorders such as obstructive apnea, or pulmonary aspiration, one must understand the many functions performed by the upper airway. These functions include respiration, airway protection at the face, feeding, and regulation of thoracoabdominal pressure. The neuromuscular mechanisms that perform t...

journal_title：Clinics in perinatology

authors： Thach BT

更新日期：1992-12-01 00:00:00

abstract：:New knowledge has accumulated in recent years making it prudent to ask questions regarding current oxygenation policies and guidelines. Because new-born resuscitation affects so many individuals, and because resuscitation procedures may have dramatic consequences on infant and child health, intensified discussion and ...

journal_title：Clinics in perinatology

authors： Saugstad OD

更新日期：2004-09-01 00:00:00

abstract：:This article discusses the management of short bowel syndrome during the neonatal period. It includes information regarding etiology and pathophysiology and parenteral and enteral nutrition therapy. Finally, a discussion of the role of intestinal transplantation in the treatment of short bowel syndrome is included. ...

journal_title：Clinics in perinatology

authors： Vanderhoof JA

更新日期：1996-06-01 00:00:00

abstract：:Although continuous positive airway pressure (CPAP) is an effective strategy to prevent invasive ventilation, failure rates are high and many babies require endotracheal intubation. Prolonged exposure to mechanical ventilation is linked with bronchopulmonary dysplasia and other morbidities. Different techniques of nas...

journal_title：Clinics in perinatology

authors： Waitz M,Mense L,Kirpalani H,Lemyre B

更新日期：2016-12-01 00:00:00

abstract：:When tissue oxygenation is impaired, compensatory mechanisms occur, including a redistribution of blood flow in order to maintain oxygen delivery to vital organs, resulting in a fall in peripheral blood flow. Monitoring peripheral oxygenation therefore has potential benefits as it may provide an early warning of chang...

journal_title：Clinics in perinatology

authors： Wardle SP,Weindling AM

更新日期：1999-12-01 00:00:00

abstract：:Prevention of harm from medication errors has become a national priority. Medication errors in the neonatal intensive care unit are common, and most can be avoided. This article reviews the prevalence and types of medication errors affecting the care of the neonate and summarizes approaches that have been used to redu...

journal_title：Clinics in perinatology

authors： Stavroudis TA,Miller MR,Lehmann CU

更新日期：2008-03-01 00:00:00

abstract：:A number of ethical considerations arise with regard to screening for, detecting, and managing fetal anomalies. Some of these considerations involve the need to give attention to emotional distress the pregnant woman might be experiencing. The ethical principle of beneficence gives rise to a duty of the obstetrician t...

journal_title：Clinics in perinatology

authors： Strong C

更新日期：2003-03-01 00:00:00

abstract：:Congenital hemiplegia is the most common form of cerebral palsy in children born at term, and stroke is the number one cause. Neonatal ischemic stroke includes perinatal arterial ischemic stroke, presumed pre- or perinatal stroke, and cerebral sinovenous thrombosis, all of which have emerged as important contributors ...

journal_title：Clinics in perinatology

authors： Kirton A,deVeber G

更新日期：2006-06-01 00:00:00

abstract：:Nonstress testing appears to be an effective means of identifying fetal condition. Its most definitive benefit is the identification of the "normal" fetus, which often permits a path of nonintervention. A significant benefit of the nonstress test approach is its simplicity and portability which, in a practical sense, ...

journal_title：Clinics in perinatology

authors： Paul RH

更新日期：1982-06-01 00:00:00

abstract：:Despite the fact that hypoglycemia is an extremely common disorder of the newborn, consensus has been difficult to reach regarding definition, diagnosis, outcome, and treatment. With improved neuroradiologic techniques, such as MRI and PET scanning becoming increasingly available, studies to determine the correlation ...

journal_title：Clinics in perinatology

authors： Yager JY

更新日期：2002-12-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a multifactorial disorder that primarily affects premature infants. Human milk compared with formula reduces the incidence of NEC. Feeding practices do not increase the incidence of NEC in preterm infants. There is no evidence supporting continuous versus intermittent tube feedings i...

journal_title：Clinics in perinatology

authors： Ramani M,Ambalavanan N

更新日期：2013-03-01 00:00:00

abstract：:The Mothers' Milk Bank (MMB) of San Jose, CA, has provided banked human milk to clinicians and researchers since its founding in 1974. This article briefly acknowledges the many and varied reasons for the use of human milk. Its primary focus however, is to review the protocol followed by the MMB for collection, bankin...

journal_title：Clinics in perinatology

authors： Asquith MT,Pedrotti PW,Stevenson DK,Sunshine P

更新日期：1987-03-01 00:00:00

abstract：:This study was undertaken to identify the pathologic processes in premature infants weighing less than 1000 gm who require surgery, and the outcome of such operations. These neonates required surgery for NEC and PDA. Congenital anomalies were not encountered in our series. No increased mortality due to surgery was obs...

journal_title：Clinics in perinatology

authors： Lemon DG,Wesselhoeft CW Jr,DeLuca FG

更新日期：1986-06-01 00:00:00

abstract：:Exogenous surfactant therapy has been a significant advance in the management of preterm infants with RDS. It has become established as a standard part of the management of such infants. Both natural and synthetic surfactants lead to clinical improvement and decreased mortality, with natural surfactants having additio...

journal_title：Clinics in perinatology

authors： Suresh GK,Soll RF

更新日期：2001-09-01 00:00:00

abstract：:Pharmacotherapy for gastroesophageal reflux (GER) in neonates, aimed at interfering with this physiologic process and potentially reducing the negative sequelae that providers often attribute to GER, consists primarily of drugs that increase the viscosity of feeds, reduce stomach acidity, or improve gut motility. Medi...

journal_title：Clinics in perinatology

authors： Malcolm WF,Cotten CM

更新日期：2012-03-01 00:00:00

abstract：:In patients with chronic renal disease, all advice and decisions must take into account the balance between pregnancy outcome and the long-term impact that pregnancy might have on the disease. To help the clinician address these concerns, the authors focus on the renal changes in normal pregnancy, the problems of chro...

journal_title：Clinics in perinatology

authors： Davison JM,Katz AI,Lindheimer MD

更新日期：1985-10-01 00:00:00

abstract：:Mitochondrial disorders present in a myriad of ways, which causes them to be included in the differential diagnosis for many patients with undiagnosed disease. A subset of mitochondrial disorders are caused by intrinsic defects in the mitochondrial replication machinery, leading to loss of cellular mitochondrial conte...

journal_title：Clinics in perinatology

authors： Basel D

更新日期：2020-03-01 00:00:00

abstract：:Correct fluid and electrolyte concentrations are essential to reduce mortality in critically ill infants. The authors list considerations in calculating the necessary maintenance volumes and emphasize the importance of continuous monitoring of data and a review and retabulation every eight hours, because requirements ...

journal_title：Clinics in perinatology

authors： Bell EF,Oh W

更新日期：1979-03-01 00:00:00

abstract：:Staphylococci are common pathogens in the neonatal period. Increased survival of premature infants leads to prolonged hospital stay with associated risk factors for developing invasive staphylococcal disease. Challenges of diagnosing coagulase-negative staphylococcal infections result in conflicting definitions and in...

journal_title：Clinics in perinatology

authors： Blanchard AC,Quach C,Autmizguine J

更新日期：2015-03-01 00:00:00

abstract：:Two different care procedures are presented to raise the difficult question of whether we should completely reevaluate our paradigms of care in the perinatal period. In this thorough review, should we continue to use the same framework of beliefs in deciding on the benefits and risks of any care procedure? ...

journal_title：Clinics in perinatology

authors： Kennell JH,Klaus MH

更新日期：1988-12-01 00:00:00

abstract：:Congenital cytomegalovirus is the most common viral congenital infection, and affects up to 2% of neonates. Significant sequelae may develop after congenital cytomegalovirus, including hearing loss, cognitive defects, seizures, and death. Zika virus is an emerging virus with perinatal implications; a congenital Zika v...

journal_title：Clinics in perinatology

authors： Wood AM,Hughes BL

更新日期：2018-06-01 00:00:00

abstract：:Stem cell transplantation (SCT) is an established first-line or adjunctive therapy for a variety of neonatal and adult diseases. New evidence in preclinical models as well as a few human studies show the potential utility of SCT in neuroprotection and in the modulation of inflammatory injury in at risk-neonates. This ...

journal_title：Clinics in perinatology

authors： Yoshimoto M,Koenig JM

更新日期：2015-09-01 00:00:00

abstract：:Scientific study of prenatal drug exposure and child outcome began a period of substantial growth in the 1970s with a focus on exposure to opiates. By the mid-1980s, attention shifted to cocaine. Most of this research has involved cohort studies in which groups of children are followed up longitudinally from birth. Si...

journal_title：Clinics in perinatology

authors： Smeriglio VL,Wilcox HC

更新日期：1999-03-01 00:00:00

abstract：:Phototherapy is now the preferred method of treatment for neonatal hyperbilirubinemia by virtue of its noninvasive nature and its relative freedom from major complications. It is also convenient, easy to use, and inexpensive in terms of personnel, equipment, and disposals. Long-term experience with phototherapy has de...

journal_title：Clinics in perinatology

authors： Tan KL

更新日期：1991-09-01 00:00:00

abstract：:Current methods of intrapartum surveillance have made little impact on fetal mortality and morbidity while leading to increased caesarean section rates. Near-infrared spectroscopy is a powerful new technique that can continuously measure changes in fetal cerebral oxygenation and hemodynamics during labor. Data are pre...

journal_title：Clinics in perinatology

authors： Peebles DM

更新日期：1997-09-01 00:00:00

abstract：:This article reviews the significance of hypoxic-ischemic encephalopathy and the associated patterns of cerebral injury in the context of the most probable timing of the insult and prognosis. The evolution of the clinical features of significant hypoxic-ischemic encephalopathy, and the diagnostic value of imaging and ...

journal_title：Clinics in perinatology

authors： Hill A,Volpe JJ

更新日期：1989-06-01 00:00:00

abstract：:Despite advances in neonatal medicine, the mortality rate for congenital diaphragmatic hernia remains high. The results of work in animal models suggest that this anomaly may be amenable to in utero surgical correction. In this article, the natural history of congenital diaphragmatic hernia in humans is reviewed, and ...

journal_title：Clinics in perinatology

authors： Neerhof MG,MacGregor SN,Kilner JF

更新日期：1996-09-01 00:00:00

abstract：:The risk of mother-to-child transmission (MTCT) of HIV can be reduced through cesarean delivery prior to the onset of labor and prior to rupture of the membranes (elective cesarean delivery [ECD]). As a result of this evidence, the American College of Obstetricians and Gynecologists and the Department of Health and Hu...

journal_title：Clinics in perinatology

authors： Legardy-Williams JK,Jamieson DJ,Read JS

更新日期：2010-12-01 00:00:00

abstract：:The fetal environment is thus well suited for normal growth and development with oxygen availability exceeding oxidative needs. With impairments in blood gas exchange this excess oxygen acts as a "margin of safety," providing for the maintenance of oxidative metabolism through increases in fractional O2 extraction, al...

journal_title：Clinics in perinatology

authors： Richardson BS

更新日期：1989-09-01 00:00:00