Abstract:
PURPOSE:Spinal anesthesia (SA) is being increasingly used in infants to avoid the potential negative neurocognitive effects of general anesthesia (GA). However, SA has been reported to provide a relatively short duration of surgical anesthesia. METHODS:We retrospectively reviewed SA cases for surgical procedures lasting more than 60 min in children up to 3 years old. All patients received bupivacaine 0.5% (1 mg/kg up to 7 mg) with clonidine 1 µg/kg ± epinephrine. The primary outcome was success of SA without subsequent conversion to GA. RESULTS:Thirty-five patients met inclusion criteria (all males, age 7 ± 5 months, weight 8 ± 2 kg). Procedures included male genital, groin and multiple site surgeries. Average surgical duration was 71 ± 12 min (range 60-111 min). SA was successful in 31 of 35 patients (89%; 95% confidence interval 78, 99%). The cause of failure was rarely due to the duration of surgery (1 of 4 patients). Six patients with successful SA required sedation with dexmedetomidine ± fentanyl. Differences in procedure duration and patient characteristics were not statistically significant between successful and failed SA. CONCLUSIONS:SA is a highly successful technique and may offer an alternative to GA in children undergoing appropriate surgery expected to last as long as 60-100 min.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Trifa M,Tumin D,Whitaker EE,Bhalla T,Jayanthi VR,Tobias JDdoi
10.1007/s00540-018-2517-5subject
Has Abstractpub_date
2018-08-01 00:00:00pages
637-640issue
4eissn
0913-8668issn
1438-8359pii
10.1007/s00540-018-2517-5journal_volume
32pub_type
杂志文章abstract:PURPOSE:Painful neuropathic conditions of cancer pain often show little response to nonopioid and opioid analgesics but may be eased by antidepressants and anticonvulsants. Although gabapentin is effective in the treatment of neuropathic pain in patients with cancer, some patients experience intolerable side effects su...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-010-0913-6
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:Unilateral spinal anesthesia is beneficial in patients undergoing unilateral leg surgery. The direction and the shape of the spinal needle are thought to influence the unilateral distribution of the local anesthetic in the intrathecal space. Therefore, to study the effects of different spinal needles we compare...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1496-1
更新日期:2013-04-01 00:00:00
abstract::To evaluate the effects of subanesthetic enflurane and sevoflurane on the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS), the blood level of norepinephrine (NE) and fluctuations in the R-R intervals were measured on electrocardiogram in humans given either 0.5 MAC enflurane or sevofluran...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02482745
更新日期:1994-03-01 00:00:00
abstract::A 75-year-old female patient underwent right vitrectomy under total intravenous anesthesia with propofol, ketamine and fentanyl. During the surgery sudden severe bradycardia (heart rate, 33 beats per min), without hypotension, occurred, which was relatively atropine-insensitive. This event was accompanied by a marked ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0632-4
更新日期:2008-01-01 00:00:00
abstract::Opioid-related postoperative nausea and vomiting should not occur following remifentanil administration because of its relatively short time to elimination. However, studies have indicated that the incidence of postoperative nausea and vomiting associated with remifentanil is similar to that with other opioids. Hence,...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-018-2550-4
更新日期:2018-10-01 00:00:00
abstract::Muscle relaxation induced by neuromuscular blocking agents (NMBAs) is necessary for tracheal intubation and immobilization during surgery. Although acetylcholinesterase inhibitors have been successfully used as antagonists for NMBAs, they have their limitations; their effects are transient and ineffective against prof...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02836-1
更新日期:2020-10-01 00:00:00
abstract::Treacher Collins syndrome (TCS) is a congenital malformation of craniofacial development; in these patients conventional direct laryngoscopy is very difficult and often unsuccessful because of the upper airway malformation. A 20-year-old man with TCS was scheduled for elective tympanoplasty. The patient showed the cha...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-007-0598-7
更新日期:2008-01-01 00:00:00
abstract::Tracheomalacia after thyroidectomy is a life-threatening situation. However, it is difficult to predict postoperative tracheal obstruction with certainty. A case of a 74-year-old woman with a long-standing adenomatous goiter (98 g) is reported. She had undergone partial right lobe thyroidectomy 54 years earlier. After...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1181-9
更新日期:2011-10-01 00:00:00
abstract::There has been no study comparing the advantage and disadvantage of various antihypertensive agents during surgery for pheochromocytomas because the study is difficult in clinical setting. In the present experiments using dogs, after increasing the arterial blood pressure with norepinephrine, we decreased it to the ba...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050396
更新日期:1991-10-01 00:00:00
abstract::The hemodynamic and metabolic changes in hypotensive state induced with prostaglandin E1 (PGE1) or trimetaphan (TMT) infusion were investigated in dogs. Mean arterial pressure was decreased by about 50% with 1.58 microg/kg/min of PGE1 or 45 microg/kg/min of TMT. Heart rate, pulmonary capillary wedge pressure and centr...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054090030210
更新日期:1989-09-01 00:00:00
abstract:PURPOSE:The study was planned to compare the sensitivity of a twitch neuromuscular monitoring test, the train-of-four (TOF), with a tetanic test, double-burst stimulation (DBS), during a subclinical dose of vecuronium. METHODS:Twenty consenting. ASA I patients (16 to 65 years of age) of both sexes were studied. The ul...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02480738
更新日期:1997-12-01 00:00:00
abstract::Cerebral injury following cardiac surgery continues to be a significant source of morbidity and mortality after cardiac surgery. A spectrum of injuries ranging from subtle neurocognitive dysfunction to fatal strokes are caused by a complex series of multifactorial mechanisms. Protecting the brain from these injuries h...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-007-0514-1
更新日期:2007-01-01 00:00:00
abstract::We report three cases with systolic anterior motion (SAM) after mitral valve plasty. Preoperative mitral valve morphology is a risk factor for SAM. The morphological characteristics of SAM have been revealed in several studies. We found a small distance between coaptation and the interventricular septum in all cases, ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1731-4
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:During the induction of anesthesia, patients are at risk of aspiration while awaiting full muscle relaxation. Magnesium has been shown to have synergistic effects with neuromuscular blocking drugs. We tested if magnesium, as an adjunct, increases the speed of onset of muscle relaxation, thereby decreasing th...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1439-x
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:Remifentanil has been available in Japan for 3 years. The use of this new opioid is considered a useful adjuvant to general anesthesia. Knowing the exact cost-effectiveness of remifentanil should lead to improved anesthetic outcomes with a reasonable cost. METHODS:This single-blinded, prospective, randomized s...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-010-1006-2
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:It has been suggested that the different degrees of fade induced by nondepolarizing neuromuscular blocking agents in repetitive muscular contractions may be due to the varying affinities or binding kinetics of presynaptic nicotinic receptors. We compared the degree of fade induced by mivacurium, cisatracurium, ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s005400300024
更新日期:2003-01-01 00:00:00
abstract::We report a case of drug-induced myoclonus possibly related to palonosetron, a second-generation 5-hydroxytryptamine-3 receptor antagonist which was administered as a prophylaxis for postoperative nausea and vomiting in a 28-year-old female. The recurrent episodes of myoclonus jerk involving the head, neck and shoulde...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2228-8
更新日期:2016-12-01 00:00:00
abstract::Takotsubo cardiomyopathy is an acute syndrome involving apical ballooning and consequent dysfunction of the left ventricle. Most cases of left ventricular dysfunction resolve within 1 month. We present the case of a 40-year-old woman who developed severe heart failure caused by takotsubo cardiomyopathy with severe lef...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1677-6
更新日期:2014-02-01 00:00:00
abstract::Recently, gastric ultrasonography has been used as a noninvasive portable tool for evaluating gastric content and volume in adults and children. Pediatric patients are not always cooperative, especially younger ones, and it may be difficult to keep them in the appropriate scanning position without sedation. Hence, we ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2204-3
更新日期:2016-10-01 00:00:00
abstract::Since perioperative anaphylaxis occurs suddenly, and it can be life-threatening, anesthesiologists need to have sufficient knowledge of the epidemiology of perioperative anaphylaxis and appropriate coping strategies to deal with it. Recent studies conducted in Western countries reported the characteristics of perioper...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02886-5
更新日期:2021-02-01 00:00:00
abstract::We present a life-threatening case of hemothorax resulting from right brachiocephalic vein perforation during right internal jugular vein catheterization. We considered that the guidewire had punctured the right brachiocephalic vein extraluminally and the catheter inserted over the guidewire had enlarged the size of t...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0696-1
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:Hypoxia promotes the progression of lung cancer cells. Unfortunately, anesthetic technique might aggravate hypoxia of lung cancer cells. Sevoflurane is a commonly used anesthetic. Its effect on hypoxia-induced aggressiveness of lung cancer cells remains unknown. The aim of the study is to investigate the effect...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-015-2035-7
更新日期:2015-12-01 00:00:00
abstract::We tested hypertonic saline solution (HS) to determine its effectiveness in surgical procedures for prostatic hypertrophy. We randomly selected 40 patients undergoing elective transurethral resection of the prostate for either infusion of HS (3% NaCl) at 4ml·kg(-1)·min(-1) (HS group) or lactated Ringer's solution (LR)...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02471385
更新日期:1996-09-01 00:00:00
abstract::Tracheal insufflation of oxygen (TRIO) is a form of constant-flow ventilation. We studied the effect of TRIO at a flow rate of 2 L/kg/min on arterial blood gases during external cardiac compressions in dogs with ventricular fibrillation. During the combined application of TRIO and external cardiac compressions, all an...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054090030016
更新日期:1989-03-01 00:00:00
abstract:PURPOSE:Although non-steroidal anti-inflammatory drugs and acetaminophen have no proven efficacy against neuropathic pain, they are frequently prescribed for neuropathic pain patients. We examined whether the combination of opioids (tramadol and morphine) with indomethacin or acetaminophen produce favorable effects on ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1953-0
更新日期:2015-06-01 00:00:00
abstract::The direct effects of nitrous oxide on left ventricular contractility and myocardial oxygen consumption (MVO2) in the ischemic isolated rat heart were studied. The rat heart was isolated and perfused by a Langendorf technique. The aortic stump was cannulated and the heart was perfused with Kumpeis solution bubbled wit...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02514658
更新日期:1994-09-01 00:00:00
abstract:PURPOSE:To examine the relationships between effect-site concentrations and electroencephalographic parameters after the induction of general anesthesia with midazolam. METHODS:Twenty-four patients with American Society of Anesthesiologists status I or II were randomly allocated to receive either an intravenous (i.v.)...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-010-0907-4
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:Local epinephrine infiltration often causes beta1-adrenoceptor-mediated tachycardia, hypertension, and arrhythmia. Landiolol, a short acting beta1-adrenoceptor blocker, may represent the most ideal agent to attenuate these adverse effects. In this study, we examined the effects of landiolol on the hemodynamic c...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00540-004-0281-1
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:We performed a multicenter, randomized, double-blind trial to assess the efficacy and safety of a single, fixed, intravenous dose of palonosetron (0.075 mg) in the treatment of established postoperative nausea and vomiting (PONV). METHODS:Three hundred and eighty-four patients who had at least one risk factors...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00540-014-1884-9
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:Patients undergoing laparoscopic gynecological surgery are susceptible to postoperative nausea and vomiting (PONV). We hypothesized that a combination of epidural and general anesthesia to minimize intraoperative opioid administration would reduce the incidence of PONV following laparoscopic gynecological surge...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-018-2525-5
更新日期:2018-08-01 00:00:00