Original Design of Fluorescent Ligands by Fusing BODIPY and Melatonin Neurohormone.

Abstract:

:An original design and synthesis of fluorescent ligands for melatonin receptor studies is presented and consists in the fusion of the endogenous ligand with the fluorescent BODIPY core. Probes I-IV show high affinities for MT1 and MT2 melatonin receptors and exhibit fluorescence properties compatible with cell observation.

journal_name

ACS Med Chem Lett

authors

Thireau J,Marteaux J,Delagrange P,Lefoulon F,Dufourny L,Guillaumet G,Suzenet F

doi

10.1021/ml4004155

subject

Has Abstract

pub_date

2013-11-20 00:00:00

pages

158-61

issue

2

issn

1948-5875

journal_volume

5

pub_type

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