Abstract:
OBJECTIVE:The present study aimed to assess the effectiveness of oral citalopram, compared with fluoxetine and a placebo, in patients with post-stroke motor disabilities. DESIGN:A randomized double-blind placebo-controlled clinical trial was conducted between January 2015 and January 2016. SETTING:The neurology department of a university-affiliated urban hospital in Tehran, Iran. SUBJECTS:Ninety adult patients with acute ischemic stroke, hemiplegia, or hemiparesis and a Fugl-Meyer Motor Scale score of below 55 were included. INTERVENTIONS:Participants were randomly allocated to one of three groups: Group A received 20 mg PO of fluoxetine daily, Group B received 20 mg PO of citalopram daily, and Group C received a placebo PO The duration of the therapy was 90 days. In addition to the medications, all of the participants received physiotherapy. MAIN MEASURES:Functional status at 90 days, which was measured by the Fugl-Meyer Motor Scale score. RESULTS:The initial mean (SD) Fugl-Meyer Motor Scale scores for the placebo, fluoxetine, and citalopram groups were 18.2 (11.42), 20.08 (14.53), and 17.07 (14.92), respectively. After 90 days, the scores were 27.96 (18.71) for the placebo group, 52.42 (26.24) for the fluoxetine group, and 50.89 (27.17) for the citalopram group. Compared with the placebo group, the mean Fugl-Meyer Motor Scale scores showed significant increases in the fluoxetine and citalopram groups ( P = 0.001). CONCLUSION:There was no significant difference between citalopram and fluoxetine in facilitating post-stroke motor recovery in ischemic stroke patients. However, compared with a placebo, both drugs improved post-stroke motor function.
journal_name
Clin Rehabiljournal_title
Clinical rehabilitationauthors
Asadollahi M,Ramezani M,Khanmoradi Z,Karimialavijeh Edoi
10.1177/0269215518777791subject
Has Abstractpub_date
2018-08-01 00:00:00pages
1069-1075issue
8eissn
0269-2155issn
1477-0873journal_volume
32pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:To compare the outcome of day hospital to day centre rehabilitation. DESIGN:Single blind randomized controlled trial with home assessments at baseline (twice), six weeks and three months. SETTING:Mainly rural health district. Day hospital and social services day centres in market towns. SUBJECTS:One hundre...
journal_title:Clinical rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1191/026921599671803291
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVE:To investigate the service users' (stroke survivors and care-givers) experiences and views of the rehabilitation assessment process. DESIGN:Qualitative data analysis from three focus groups using a content analysis to identify the major themes. SETTING:Participants were recruited from stroke support groups ...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1177/0269215514523300
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:To assess whether the addition of an education programme for primary caregivers to rehabilitation improves daily functioning in children with cerebral palsy. DESIGN:A randomized, single-blind, controlled study. SETTING:This study was conducted in a rehabilitation centre in Salvador, Brazil. PARTICIPANTS:A ...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1177/0269215518757051
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:The objective was to investigate the effect of increased intensity of rehabilitation therapy provided to brain-injured subjects on the rate at which independence was regained and the duration of hospital admission. DESIGN:A two-centre, prospective, controlled study with random allocation to groups. SETTING:...
journal_title:Clinical rehabilitation
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1191/026921501680425225
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the short-term effectiveness of an intensive multidisciplinary rehabilitation programme for people with Parkinson's disease and their carers. DESIGN:Observational, with assessments before and after intervention. SETTING:An elderly care day unit in a district general hospital in south-east Englan...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1191/0269215502cr545oa
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of behavioural activation interventions for people with neurological conditions with comorbid depression, and explore content and adaptations. DATA SOURCES:PsycINFO, MEDLINE, CINAHL, AMED, and EMBASE databases were searched on the 19 November 2019. Reference lists of selected fu...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1177/0269215519896404
更新日期:2020-03-01 00:00:00
abstract:PRIMARY OBJECTIVE:To appraise recent studies regarding the needs and experiences of caregivers of individuals with multiple sclerosis (MS). DESIGN:The following computerized databases were searched: CINAHL, BIDS IBSS, ASSIA, MEDLINE, PSYCHINFO, British Nursing Index, ISI Web of Science, Zetoc, AMED (1990-April 2002). ...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,评审
doi:10.1191/0269215503cr618oa
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To examine the effect of constraint-induced movement therapy and modified constraint-induced movement therapy on activity and participation of patients with stroke (i.e. the effect of different treatment durations and frequency) by reviewing the results of randomized controlled trials. DATA SOURCES:A systema...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,meta分析,评审
doi:10.1177/0269215511420306
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:To explore the inter-observer reliability of bedside observations of stroke patients' posture using two versions of a pictorial tool. DESIGN:Three projects were conducted. The initial version of the tool was used in project 1. The modified version was used in projects 2 and 3. In each project a pair of obser...
journal_title:Clinical rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1177/026921559901300307
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVES:To establish the measurement properties of TURN180, a test of dynamic postural stability. DESIGN:One physiotherapist conducted three trials of TURN 180, one of which was also observed by a second therapist. SETTING:A day unit for elderly people accepting both inpatients and outpatients. SUBJECTS:Sixty-six...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1191/0269215505cr783oa
更新日期:2005-06-01 00:00:00
abstract:PURPOSE:The aim was to describe experiences of disability in everyday life and managing the recovery process two years after falling ill with Guillain-Barré syndrome. DESIGN:Qualitative interview study. METHODS:Interviews were conducted with 35 persons (22 male, mean age 50 years) two years after the onset of Guillai...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1177/0269215514549564
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:Does early treatment of spasticity with botulinum-toxin (BoNTA), in (hyper)acute stroke patients without arm-function, reduce contractures and improve function. DESIGN:Randomised placebo-controlled-trial. SETTING:Specialised stroke-unit. PARTICIPANTS & INTERVENTION:Patients with an Action Research Arm Test...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1177/0269215520963855
更新日期:2020-10-11 00:00:00
abstract:OBJECTIVE:To explore, following a literature review, whether there is a consistent definition and a unified assessment framework for the term 'spasticity'. The congruence between the definitions of spasticity and the corresponding methods of measurement were also explored. DATA SOURCES:The search was performed on the ...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,评审
doi:10.1177/0269215508101747
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:To compare the feasibility, convergent and clinical validity of three commonly used burden scales: Caregiver Strain Index (CSI), Caregiver Reaction Assessment (CRA) and Sense of Competence Questionnaire (SCQ), with a self-developed single question on self-rated burden (SRB). SUBJECTS:Stroke patients receivin...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1191/0269215504cr723oa
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:To compare spinal manipulation, back school and individual physiotherapy in the treatment of chronic low back pain. DESIGN:Randomized trial, 12-month follow-up. SETTING:Outpatient rehabilitation department. PARTICIPANTS:210 patients with chronic, non-specific low back pain, 140/210 women, age 59 +/- 14 yea...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1177/0269215509342328
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To investigate whether Kinesio taping technique, applied to ankles of healthy people as a preventive intervention and people with ankle injuries, is superior to sham or alternative interventions on ankle function. DATA SOURCES:Medline, Embase, Amed, CINAHL, SPORTDiscus, Cochrane Library and Web of Science, f...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1177/0269215520963846
更新日期:2020-10-20 00:00:00
abstract:OBJECTIVE:To determine the effects of pre- and postoperative inspiratory muscle training on length of postoperative hospital stay and pulmonary function in patients undergoing cardiac surgery. DESIGN AND METHODS:We conducted a systematic search using databases (MEDLINE, CINAHL, EMBASE, PEDro and the Cochrane) to find ...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,meta分析,评审
doi:10.1177/0269215516648754
更新日期:2017-04-01 00:00:00
abstract::The total extent of sickness in the population has increased while disease has decreased. Being sick is a role that offers the patient many advantages both directly, in terms of being absolved from undertaking many daily activities if necessary, and indirectly, through additional financial and other resources that may...
journal_title:Clinical rehabilitation
pub_type: 社论
doi:10.1177/0269215507077799
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the feasibility, internal consistency and reproducibility of the French version of the Nottingham Health Profile (NHP) completed by adults with hereditary neuromuscular disease. DESIGN:Cross-sectional study with evaluation at 15 +/- 7 days for NHP test-retest. SETTING:Multidisciplinary rehabilit...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1191/0269215505cr858oa
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Goal achievement has been considered to be an important measure of outcome by clinicians working with patients in physical and neurological rehabilitation settings. This systematic review was undertaken to examine the reliability, validity and sensitivity of goal setting and goal attainment scaling approache...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,评审
doi:10.1177/0269215506070793
更新日期:2006-09-01 00:00:00
abstract::This series of articles for rehabilitation in practice aims to cover a knowledge element of the rehabilitation medicine curriculum. Nevertheless they are intended to be of interest to a multidisciplinary audience. The competency addressed in this article is 'The trainee consistently demonstrates a knowledge of the pat...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1177/0269215509353254
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:This study aims to evaluate the prevalence and determinants of inadequate physical activity and excessive sedentary behaviour before and after total knee replacement. DESIGN, SETTING AND SUBJECTS:Secondary analysis was performed on data from a cohort of 422 adults (45-74 years), drawn from 12 public or priva...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1177/0269215518769986
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:This systematic review aimed to examine the effects of dual-task balance and mobility training in people with stroke. METHODS:An extensive electronic databases literature search was conducted using MEDLINE, PubMed, EBSCO, The Cochrane Library, Web of Science, SCOPUS, and Wiley Online Library. Randomized cont...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1177/0269215518758482
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:To assess whether intraarticular corticosteroids improve the outcome of a comprehensive home exercise programme in patients with adhesive capsulitis. SETTING:The study was undertaken in the Physical Therapy and Rehabilitation Department of a Ministry of Health hospital in Turkey. SUBJECTS:Eighty patients wi...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1177/0269215508086179
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of kinesiology taping and different types of application techniques of kinesiology taping in addition to therapeutic exercises in the treatment of congenital muscular torticollis. DESIGN:Prospective, single blind, randomized controlled trial. SETTING:An outpatient rehabilitation c...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1177/0269215516673885
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy of three-dimensional (3D) Schroth exercises in patients with adolescent idiopathic scoliosis. DESIGN:A randomised-controlled study. SETTING:An outpatient exercise-unit and in a home setting. SUBJECTS:Fifty-one patients with adolescent idiopathic scoliosis. INTERVENTIONS:Forty-five ...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1177/0269215515575745
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:To compare self-report measures of daily activities with objective activity data to determine whether patients with chronic lower back pain report their activity levels as accurately as controls do. DESIGN:A cross-sectional study was performed in patients and controls. SETTING:The study was carried out in t...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1177/0269215510380828
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To compare the well-being of stroke patients' relatives with that of a reference group, and to identify variables related to the well-being of the relatives. DESIGN:Cross-sectional study. SETTING:Outpatient hospital department and patients' and relatives' own homes. SUBJECTS:Fifty-four patients one year af...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1191/0269215503cr627oa
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:To examine the criterion validity of lower extremity Motricity Index scores. DESIGN:Retrospective cross-sectional comparison of lower extremity Motricity Index scores and hand-held dynamometer measurements obtained from 15 patients with stroke. RESULTS:For individual actions (ankle dorsiflexion, knee extens...
journal_title:Clinical rehabilitation
pub_type: 杂志文章
doi:10.1191/026921500675786655
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of body awareness therapy on balance, mobility, balance confidence, and subjective health status in persons with stroke. DESIGN:A pilot randomized controlled study with follow-up at one and 4-6 weeks after the intervention period. SETTING:Four primary healthcare centres in Örebro ...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/0269215514527994
更新日期:2014-12-01 00:00:00