Abstract:
:Methamphetamine and HIV impair thyroid function, but few studies have investigated their combined effects on thyroid dysregulation. This study examined the associations of methamphetamine use alone and in combination with HIV on thyroid function among men in South Florida. Measures of thyroid function in methamphetamine-using, HIV-infected (METH+HIV+; n = 127) and HIV-negative (METH+HIV-; n = 46) men who have sex with men (MSM) were compared to non-methamphetamine-using, HIV-negative men (METH-HIV-; n = 136). Thyroid function was dysregulated in methamphetamine-using MSM, irrespective of HIV status. Both meth-using groups had greater odds of abnormal thyroid stimulating hormone levels and significantly higher mean free triiodothyronine (T3) levels. Elevated free T3 was associated with greater depressive symptoms. Overall, outcomes have important implications for assessment of thyroid function in methamphetamine users, particularly among those presenting with depression.
journal_name
J Behav Medjournal_title
Journal of behavioral medicineauthors
Jones DL,Carrico AW,Babayigit S,Rodriguez VJ,Aguila C,Kumar Mdoi
10.1007/s10865-018-9935-6subject
Has Abstractpub_date
2018-12-01 00:00:00pages
792-797issue
6eissn
0160-7715issn
1573-3521pii
10.1007/s10865-018-9935-6journal_volume
41pub_type
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