Lysophosphatidylcholine as a predictor of postoperative complications after colorectal cancer surgery.

Abstract:

PURPOSE:Lysophosphatidylcholine (LPC), which is generated from phosphatidylcholine (PC) and metabolized by autotaxin (ATX), modulates immune responses via its anti-inflammatory property. We investigated the association between LPC and postoperative complications (POCs) after colorectal cancer surgery (CRC). METHODS:The subjects of this study were 43 patients who underwent surgery for CRC. Peripheral blood samples were collected preoperatively and immediately after surgery, and on postoperative days (PODs) 1, 3, 5, and 7. Patients were divided into a No-POC group (n = 33) and a POC group (n = 10). Blood LPC, IL-6, PC, and ATX levels were measured by specific enzymatic assays or ELISA. RESULTS:The postoperative to preoperative LPC ratios were lowest on POD 1 in both groups. The POC group had significantly lower LPC ratios throughout the perioperative period than the No-POC group. The LPC ratios were inversely correlated with IL-6. The predictive impact of LPC ratios on POCs was demonstrated by ROC analysis (cut-off 51.2%, AUC 0.798) and multivariate analysis (OR 15.1, P = 0.01). The postoperative PC ratios decreased more after surgery in the POC group. ATX levels did not change significantly in either group. CONCLUSIONS:Decreased postoperative LPC is associated with increased postoperative inflammatory response and POCs. The decreased PC supply to the circulation is a mechanism of the postoperative LPC decrease.

journal_name

Surg Today

journal_title

Surgery today

authors

Matsuda A,Yamada M,Matsumoto S,Sakurazawa N,Yamada T,Matsutani T,Miyashita M,Uchida E

doi

10.1007/s00595-018-1675-2

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

936-943

issue

10

eissn

0941-1291

issn

1436-2813

pii

10.1007/s00595-018-1675-2

journal_volume

48

pub_type

杂志文章
  • Modified double-stapling technique in low anterior resection for lower rectal carcinoma.

    abstract:PURPOSE:The original double-stapling technique (DST) using a standard linear stapler horizontally can be difficult in patients with a narrow pelvis or an ultralow anastomosis. We review our experience of performing a modified DST (IO-DST) with vertical division of the rectum achieved using an endostapler. METHODS:We r...

    journal_title:Surgery today

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00595-005-3088-2

    authors: Sato H,Maeda K,Hanai T,Matsumoto M,Aoyama H,Matsuoka H

    更新日期:2006-01-01 00:00:00

  • Primary gastric T-cell lymphoma without human T-lymphotropic virus type 1: report of a case.

    abstract::Although primary gastric malignant lymphoma accounts for slightly more than 10% of all lymphomas at extranodular sites, it is relatively rare clinically, representing only 1% of all malignant diseases of the stomach. In addition, most such diseases tend to be B-cell lymphoma, while T-cell lymphoma is extremely rare. W...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s005950200091

    authors: Watanabe M,Moriyama Y

    更新日期:2002-01-01 00:00:00

  • Simultaneous rupture of the liver and spleen in a patient on warfarin therapy: report of a case.

    abstract::Although there are many reports describing spontaneous rupture of either the spleen or the liver, the simultaneous rupture of both organs is a rare event, especially during anticoagulant therapy. We report a case of spontaneous rupture of the spleen and liver in a patient on warfarin therapy for deep venous thrombosis...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-004-2898-y

    authors: Kapan M,Kapan S,Karabicak I,Bavunoglu I

    更新日期:2005-01-01 00:00:00

  • Life-threatening complications after pulmonary resection for lung cancer in patients on chronic hemodialysis.

    abstract:PURPOSE:The morbidity and mortality associated with lung cancer surgery in patients on chronic hemodialysis (CHD) is high; however, the relationship between the severity of postoperative complications and clinicopathological features is unclear. METHODS:Among 1214 consecutive patients who underwent pulmonary resection...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-019-1773-9

    authors: Tomizawa K,Sato K,Ohara S,Fujino T,Koga T,Nishino M,Kobayashi Y,Chiba M,Shimoji M,Suda K,Takemoto T,Mitsudomi T

    更新日期:2019-06-01 00:00:00

  • Psoas abscess complicating Crohn's disease: report of two cases.

    abstract::We report herein the cases of two patients with Crohn's disease complicated by a psoas abscess. The first patient was a 29-year-old man who underwent definitive surgery after acute inflammation had been controlled by nutritional therapy. In the second patient, a 37-year-old man, the abscess required drainage under loc...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00311604

    authors: Funayama Y,Sasaki I,Naito H,Tsuchiya T,Takahashi M,Koyama K,Masuko T,Takahashi K,Hiwatashi N,Matsuno S

    更新日期:1996-01-01 00:00:00

  • Traction-type heart stabilizer for off-pump coronary bypass grafting.

    abstract::We designed a stabilizer to assist us in performing coronary artery bypass grafting on the beating heart. The stabilizer consists of a U-shaped holed platform, an articulating arm, and a clamp for attachment to an ordinary sternal retractor. The target coronary artery is dissected, then two elastic sutures, 15-20mm ap...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950170210

    authors: Morishita K,Komatsu K,Kuwaki K,Koshino T,Abe T

    更新日期:2001-01-01 00:00:00

  • Alpha-Fetoprotein-producing esophageal adenocarcinoma: report of a case.

    abstract::Alpha-fetoprotein (AFP)-producing esophageal tumors are extremely rare. We report herein the case of a 51-year-old man found to have an AFP-producing adenocarcinoma arising from esophageal proper mucosa. The patient presented for investigation of dysphagia, and esophagogram and endoscopy revealed a lesion about 2 cm i...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950170035

    authors: Kobayashi N,Ohbu M,Kuroyama S,Kikuchi S,Shimao H,Mitomi H,Kakita A

    更新日期:2001-01-01 00:00:00

  • Long-term clinical results of highly selective vagotomy performed between 1980 and 1990.

    abstract::A retrospective analysis was conducted of 778 patients who underwent highly selective vagotomy between 1980 and 1990. Surgery was performed for duodenal ulcers without any complications in 485 (62.3%) patients; for duodenal ulcers with complications such as stenosis, bleeding, or perforation in 270 (34.7%); for combin...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00311565

    authors: Ihász M,Bátorfi J,Bálint A,Fazekas T,Máté M,Pòsfai G,Sándor J

    更新日期:1996-01-01 00:00:00

  • Portal vein thrombosis after splenectomy successfully treated by an enormous dosage of fibrinolytic agent in a short period: report of two cases.

    abstract::Portal vein thrombosis (PVT) after splenectomy in a patient with portal hypertension occurs with unusually high frequency. Recently, two patients with PVT following splenectomy were treated by fibrinolytic therapy with an enormous dosage of urokinase (UK) in a short period. PVT was quickly dissolved without side effec...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00308800

    authors: Suzuki S,Nakamura S,Baba S,Sakaguchi S,Ohnuki Y,Yokoi Y,Nishiyama R

    更新日期:1992-01-01 00:00:00

  • Esophagectomy for thoracic esophageal cancer with a double aortic arch: report of a case.

    abstract::We report the case of a 50-year-old man with a double aortic arch who underwent esophagectomy for cancer in the middle thoracic esophagus at clinical Stage IIA (T3N0M0), based on the TNM classification (UICC 2002). The patient underwent esophagectomy with three-field lymphadenectomy following neoadjuvant chemotherapy....

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-010-4408-8

    authors: Matono S,Fujita H,Tanaka T,Tanaka Y,Nagano T,Nishimura K,Murata K,Sueyoshi S,Shirouzu K

    更新日期:2011-08-01 00:00:00

  • A patient with early gallbladder cancer derived from a Rokitanski-Aschoff sinus.

    abstract::We present herein a case of a 40-year-old male with early gallbladder cancer derived from a Rokitanski-Aschoff sinus (RAS). The patient originally presented at our hospital with epigastric discomfort, following which a diagnosis of adenomyomatosis (ADM) of the gallbladder was made, and a cholecystectomy performed. His...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00309054

    authors: Funabiki T,Matsumoto S,Tsukada N,Kimura T,Yoshizaki S,Horibe Y

    更新日期:1993-01-01 00:00:00

  • Indications for laparoscopic surgery for older rectal cancer patients with comorbidities.

    abstract:PURPOSE:Given the lack of safety studies concerning laparoscopic surgery for rectal cancer in patients ≥ 80 years old with comorbidities, we sought to investigate this in the current study. METHODS:Between 2012 and 2019, 24 patients ≥ 80 years old underwent laparoscopic surgery for rectal cancer without preoperative t...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-020-02140-1

    authors: Hisamatsu Y,Kuriyama N,Fujimoto Y,Jogo T,Hu Q,Hokonohara K,Nakanishi R,Ando K,Kimura Y,Oki E,Mori M

    更新日期:2020-09-17 00:00:00

  • Clinical and pathological features of intracystic papillary carcinoma of the breast.

    abstract:PURPOSE:To evaluate the clinicopathological features of intracystic papillary carcinoma (ICPC), which have not been established given its rarity and lack of standard diagnostic criteria. METHODS:We reviewed the clinicopathological findings and treatment outcomes of 14 patients with ICPC diagnosed between 2002 and 2006...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-3792-9

    authors: Akagi T,Kinoshita T,Shien T,Hojo T,Akashi-Tanaka S,Murata Y

    更新日期:2009-01-01 00:00:00

  • Hemodynamic and humoral effects of atrial natriuretic peptide on pulmonary circulation after cardiac surgery.

    abstract:PURPOSE:Human atrial natriuretic peptide (h-ANP) elicits biological effects such as natriuresis, diuresis, and vasodilation, and plays a role in regulating pulmonary circulation. We conducted this clinical study to define its role and elucidate its mechanisms. METHODS:Twelve consecutive adult patients scheduled to und...

    journal_title:Surgery today

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00595-007-3649-7

    authors: Morimoto K,Taniguchi I,Miyasaka S,Ishiguro S,Ohgi S

    更新日期:2008-01-01 00:00:00

  • Successful surgical treatment for spontaneous retroperitoneal hematoma in polycythemia vera: report of a case.

    abstract::Bleeding is a common complication of such myeloproliferative disorders as polycythemia vera, and it usually occurs in either the skin or mucosa. We experienced a case of a massive retroperitoneal hematoma with no history of trauma in association with polycythemia vera. A 68-year-old man was referred to our hospital as...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950050044

    authors: Ishihara S,Yasuhara H,Ogawa S,Muto T

    更新日期:2000-01-01 00:00:00

  • Inflammatory pseudotumor of the liver masquerading as hepatocellular carcinoma after a hepatitis B virus infection: Report of a case.

    abstract::We report a rare case of hepatic inflammatory pseudotumor (IPT) after a hepatitis B virus (HBV) infection. Early contrast enhancement on computed tomography (CT) with a washout phenomenon at the delayed phase, and depleted Kupffer cell function on superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance imaging...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3306-6

    authors: Akatsu T,Wakabayashi G,Tanimoto A,Kameyama K,Kitajima M

    更新日期:2006-01-01 00:00:00

  • Intracystic carcinoma of the male breast: report of a case.

    abstract::We experienced a very rare case of male intracystic breast carcinoma. A 66-year-old man presented at our hospital because of a palpable mass in his right breast. The imaging diagnosis was an intracystic carcinoma with hemorrhagic fluid and two mural nodules. Modified radical mastectomy was performed under general anes...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950170052

    authors: Tochika N,Takano A,Yoshimoto T,Tanaka J,Sugimoto T,Kobayashi M,Matsuura K,Araki K,Ogawa Y,Moriki T

    更新日期:2001-01-01 00:00:00

  • Systematic review of the implementation of simulation training in surgical residency curriculum.

    abstract:PURPOSE:We reviewed the literature regarding the specific methods and strategies for implementing simulation-based training into the modern surgical residency curriculum. Residency programs are still struggling with how best to implement it into their curricula from a practical viewpoint. METHODS:A systematic review w...

    journal_title:Surgery today

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00595-016-1455-9

    authors: Kurashima Y,Hirano S

    更新日期:2017-07-01 00:00:00

  • Short-term outcomes of laparoscopic surgery for Crohn's disease patients treated with anti-tumor necrosis factor alpha agents.

    abstract:PURPOSE:The impact of anti-tumor necrosis factor alpha (TNFα) treatment for Crohn's disease (CD) on surgical outcomes is still controversial. The aim of this study was to assess the feasibility of laparoscopic surgery for CD patients treated preoperatively with anti-TNFα agents. METHODS:We investigated, retrospectivel...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-016-1375-8

    authors: Hata T,Mizushima T,Osawa H,Takahashi H,Haraguchi N,Nishimura J,Hata T,Takemasa I,Ikenaga M,Nakajima K,Yamamoto H,Murata K,Doki Y,Mori M

    更新日期:2017-03-01 00:00:00

  • A new method of anterior mediastinal tracheostomy following resection of cervical esophagus and the larynx: report of a case.

    abstract::We report herein the case of a 52-year-old man for whom a split pectoralis major myocutaneous flap was applied at the time of extended radical surgery for esophageal carcinoma with tracheal involvement, to avoid the postoperative complications of anterior tracheostomy such as tracheal necrosis and rupture of the major...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF01884577

    authors: Kimura A,Nimura Y,Hayakawa N,Yasui A,Torii S

    更新日期:1994-01-01 00:00:00

  • Right hemi-reconstruction of the left atrium using two equine pericardial patches for recurrent malignant fibrous histiocytoma: report of a case.

    abstract::We report a case of recurrent malignant fibrous histiocytoma (MFH) in the left atrium, treated by removal of the tumor and the right half of the left atrium, which was reconstructed with two equine pericardial patches. Postoperative echocardiography showed patent right pulmonary veins and a properly shaped left atrium...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-3920-6

    authors: Inoue H,Iguro Y,Matsumoto H,Ueno M,Higashi A,Sakata R

    更新日期:2009-01-01 00:00:00

  • Dedifferentiation of neoplastic cells in medullary thyroid carcinoma: report of a case.

    abstract::We report herein the unusual case of a man who was diagnosed as having sporadic medullary thyroid carcinoma (MTC) at the age of 29 years, and subsequently followed up for a period of 18 years. A total thyroidectomy with radical neck dissection was initially performed, followed by a stable interval of 16 years with reg...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02482271

    authors: Osaka M,Soga J,Tamiya Y,Suzuki T

    更新日期:1999-01-01 00:00:00

  • Clinical characteristics of ischemic colitis after surgery for colorectal cancer.

    abstract:PURPOSE:This study was performed to clarify the clinical features of ischemic colitis (IC) after colorectal cancer surgery. METHODS:This study retrospectively reviewed the medical records of 35 patients with IC. Patients were divided into two groups: those who had undergone colorectal cancer surgery (POIC group, n = 1...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-013-0661-y

    authors: Sato H,Koide Y,Shiota M,Endo T,Matsuoka S,Maeda K

    更新日期:2014-06-01 00:00:00

  • A case-matched comparison of single-incision versus multiport laparoscopic right colectomy for colon cancer.

    abstract:PURPOSE:To minimize the parietal trauma associated with multiple surgical access sites, single-incision laparoscopic surgery for colectomy has been emerging with the improvements in instrumentation and surgical techniques. The purpose of this study was to compare the clinicopathological outcomes between single-incision...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-015-1154-y

    authors: Suzuki O,Nakamura F,Kashimura N,Nakamura T,Takada M,Ambo Y

    更新日期:2016-03-01 00:00:00

  • Surgical treatment of massive splenomegaly and severe hypersplenism secondary to extrahepatic portal venous obstruction in children.

    abstract:PURPOSE:Massive splenomegaly with severe hypersplenism can occur as a late complication of portal hypertension (PH) caused by extrahepatic portal venous obstruction (EHPVO) in children. Severe hypersplenism is often refractory to treatment with endoscopic sclerotherapy (EST) and shunt surgery. We report our experience ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3333-3

    authors: Subhasis RC,Rajiv C,Kumar SA,Kumar AV,Kumar PA

    更新日期:2007-01-01 00:00:00

  • c-Met expression in a gastric cancer cell line producing alpha-fetoprotein.

    abstract:PURPOSE:We previously reported a higher frequency of c-Met protein expression and high proliferative status in gastric cancers producing alpha-fetoprotein (AFP) than in those not producing AFP. METHODS:To investigate this further, we established an AFP-producing gastric cancer cell line, designated as AME-1, from the ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-003-2668-2

    authors: Amemiya H,Kono K,Takahashi A,Kamei S,Sugai H,Ichihara F,Fujii H,Matsumoto Y

    更新日期:2004-01-01 00:00:00

  • The superior approach with the stomach roll-up technique improves intraoperative outcomes and facilitates learning laparoscopic distal pancreatectomy: a comparative study between the superior and inferior approach.

    abstract:PURPOSE:We introduced a superior approach and a unique technique to retract the stomach, called the "stomach roll-up technique", to standardize laparoscopic distal pancreatectomy and increase educational effectiveness. The aim of this study was to evaluate the clinical outcomes of these procedures. METHODS:Forty-five ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-019-01855-0

    authors: Morikawa T,Ishida M,Takadate T,Hata T,Iseki M,Kawaguchi K,Ohtsuka H,Mizuma M,Hayashi H,Nakagawa K,Motoi F,Kamei T,Naitoh T,Unno M

    更新日期:2020-02-01 00:00:00

  • Is the cleft lift procedure for non-acute sacrococcygeal pilonidal disease a definitive treatment? Long-term outcomes in 74 patients.

    abstract:PURPOSE:No definitive surgical treatment for non-acute pilonidal disease has been established thus far. We herein report the short-term and long-term outcomes of 74 consecutive patients who underwent the cleft lift procedure for non-acute pilonidal disease. METHODS:A total of 74 consecutive patients who underwent the ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-014-0923-3

    authors: Ortega PM,Baixauli J,Arredondo J,Bellver M,Sánchez-Justicia C,Ocaña S,Hernández-Lizoain JL

    更新日期:2014-12-01 00:00:00

  • The tumor doubling time is a useful parameter for predicting the histological type of thymic epithelial tumors.

    abstract:PURPOSE:We assessed the utility of the tumor doubling time (TDT) for predicting the histological type of thymic epithelial tumors. METHODS:We retrospectively reviewed 130 patients with thymic epithelial tumors who underwent computed tomography two or more times before surgery. The patients were divided into low-risk t...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-019-01822-9

    authors: Fukumoto K,Fukui T,Kawaguchi K,Nakamura S,Hakiri S,Ozeki N,Mori S,Goto M,Hashimoto K,Tateyama H,Yokoi K

    更新日期:2019-08-01 00:00:00

  • Landiolol reduces coronary artery motion in an open-chest porcine model: implications for off-pump coronary artery bypass surgery.

    abstract::Reduction of target coronary artery motion is imperative for successful off-pump coronary artery bypass surgery. We hypothesized that landiolol, a novel ultra-short-acting selective β-1 blocker, would reduce such coronary artery motion. To test this hypothesis, the motion of the left anterior descending artery of the ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-011-0047-y

    authors: Wakamatsu H,Watanabe T,Sato Y,Takase S,Omata S,Yokoyama H

    更新日期:2012-01-01 00:00:00