Abstract:
OBJECTIVES:Gas exchange measurements obtained during submaximal exercise have been shown to provide prognostic and diagnostic information in patients with heart failure (HF) and to differentiate heart versus lung limitations in patients with unexplained dyspnea. The aim of our study was to assess the clinical utility of submaximal cardiopulmonary exercise testing using the Shape-HF equipment in identifying the cause of unexplained dyspnea. METHODS:A total of 65 patients underwent Shape-HF tests from September 2010 to June 2011 for unexplained dyspnea at our center. RESULTS:Of 65 patients, 39 were men and 26 were women. In this study, 23 patients had preexisting asthma or chronic obstructive pulmonary disease (COPD); 19 patients had a pacemaker (8), an implantable cardioverter defibrillator (2), or a cardiac resynchronization therapy defibrillator (CRT-D) (9). The study revealed that submaximal cardiopulmonary exercise testing provided supportive clinical data for deconditioning, pulmonary limitations (eg, COPD, interstitial lung disease, sleep apnea), pulmonary hypertension, and chronotropic incompetence in 21.5%, 23.1%, 13.8%, and 6.2% of patients, respectively. Pulmonary hypertension was confirmed in 55% of patients by echocardiography and lung problems were confirmed in 40% of patients by pulmonary function test and sleep study. Of nine patients with an implanted CRT-D, optimization of atrioventricular and interventricular programming was performed in seven (78%) using gas exchange monitoring while performing a steady state, low-level treadmill walk. CONCLUSIONS:Submaximal cardiopulmonary exercise testing has strongly suggested the diagnosis of COPD, interstitial lung disease, pulmonary hypertension, and deconditioning and has led to appropriate testing. Based on prior studies, we also used Shape-HF for its approved purpose of optimizing CRT-D programming in patients with HF, leading to clinical improvement.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Bhatt DV,Kocheril AGdoi
10.1097/SMJ.0000000000000066subject
Has Abstractpub_date
2014-03-01 00:00:00pages
144-9issue
3eissn
0038-4348issn
1541-8243pii
SMJ13137journal_volume
107pub_type
杂志文章abstract:OBJECTIVES:This study evaluated the role of ankle-brachial index (ABI) as an effective screening test of coronary artery disease (CAD) in the Hispanic population. METHODS:This was an observational cross-sectional study, based on a retrospective review of the medical management of the study patients using already avail...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e318189aabc
更新日期:2008-11-01 00:00:00
abstract::Clinicians should be on the alert for the possibility of underlying thyrotoxicosis in patients having an affective disturbance. An initial detailed medical history and complete physical examination is essential even in severely agitated, threatening patients. The danger of inappropriate diagnosis and treatment of thes...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198811000-00032
更新日期:1988-11-01 00:00:00
abstract::Using a phylogenic classification of the spine, one can identify precisely the numerical location of any vertebra or disc, including vertebrae with junctional anomalies at transitional zones. Such precision permitted comparisons of myelographic reports of sites of disc disease with the actual levels of extradural defo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197909000-00017
更新日期:1979-09-01 00:00:00
abstract::There is controversy in the medical literature regarding the significance of "sickle cell cardiomyopathy." In an attempt to clarify this, we studied 14 patients with sickle cell anemia (age range 16 to 36 years) using simultaneous echocardiography and phonocardiography. The values of systolic time intervals and echoca...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198003000-00020
更新日期:1980-03-01 00:00:00
abstract::We performed a retrospective study to determine the sensitivity of mammography in detecting breast cancer arising in women with augmented breasts. Of eight women with breast implants in whom breast cancer developed, six had mammograms before biopsy. Only two of the six cancers were identified mammographically (sensiti...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199101000-00013
更新日期:1991-01-01 00:00:00
abstract::Transchondral talar dome fractures are a rare but not unknown cause of continued disability following a "sprained ankle." The diagnosis is made with standard ankle roentgenograms and an awareness of the lesion. Surgical treatment is recommended in acute and chronic cases, based on the amount of displacement of the fra...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198405000-00007
更新日期:1984-05-01 00:00:00
abstract::We report a case of recurrent Merkel cell carcinoma (MCC) of the upper extremity, treated aggressively with wide local excision, regional lymphadenectomy, and immediate reconstruction. Five years after surgery, there is no clinical or diagnostic evidence of locoregional recurrence or distant disease. The patient's upp...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::Primary malignant melanoma of the oral cavity is uncommon. Four cases are presented. The average age is in the sixth decade. Early diagnosis is difficult and prognosis is generally poor. Efforts toward earlier detection and treatment are recommended. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198002000-00045
更新日期:1980-02-01 00:00:00
abstract::Maffucci's syndrome in a 17-year-old girl is reported. Since the entity was first described in 1881 by Maffucci, 105 additional cases have been recorded. Several series have reported a small but significant percentage of cases (up to 18%) with malignant change. Our case, although not particularly unique in comparison ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197804000-00033
更新日期:1978-04-01 00:00:00
abstract::Interaction of allergen with T-cells is associated with patterns of cytokine release by immunocompetent cells characterized as T-helper Th1 or Th2 T-immune responses. The Th2 pattern of inflammation induced by this cytokine release is associated with allergic diseases. The molecular mechanisms underlying allergic infl...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.SMJ.0000097887.04639.39
更新日期:2003-11-01 00:00:00
abstract::Most patients with intestinal obstruction have had previous surgery. Rarely, the development of adhesions and resulting small bowel obstruction is attributed to previous intra-abdominal trauma. We present the case of a young man, without a history of surgery, who had been a restrained driver in a motor vehicle crash. ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2001-05-01 00:00:00
abstract::This study investigated the efficacy of perioperative antibiotics in preventing bacteremic infection of vascular suture lines, Dacron grafts, and bovine heterografts. One hundred forty-nine dogs had either segmental excision of the abdominal aorta with primary repair, Dacron prosthesis, or bovine heterograft placement...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197710001-00019
更新日期:1977-10-01 00:00:00
abstract:OBJECTIVES:The objectives of the study were to determine the percentage of osteopathic emergency medicine (EM) residencies that require an original research project to meet the American Osteopathic Association requirement, describe the resources available to the residents and faculty members to complete their projects,...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000967
更新日期:2019-05-01 00:00:00
abstract::We have presented a case of pregnancy complicated by diabetes insipidus. Treatment with desmopressin acetate (DDAVP) appropriately managed the DI, and was not associated with a worsening of the condition as pregnancy progressed. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198706000-00026
更新日期:1987-06-01 00:00:00
abstract::While in most states information physicians obtain from the about patients is confidential and cannot be disclosed without the patient's permission, a recent California Supreme Court decision affirms that when the doctor reasonably believes his patient can cause violent harm to third persons, he had an overriding duty...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197903000-00030
更新日期:1979-03-01 00:00:00
abstract::A woman with diabetes mellitus and coronary artery disease developed pneumonia and bacteremia from Branhamella catarrhalis. This is only the fifth reported case of pneumonia with bacteremia due to this organism, which was previously considered normal upper airway flora. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198910000-00035
更新日期:1989-10-01 00:00:00
abstract::A patient with pancytopenia, severe sensory neuropathy, and a six-year history of excessive vitamin intake showed portal hypertension on evaluation. A liver biopsy revealed hypervitaminosis A. His sensory findings were characteristic of a recently described syndrome of sensory neuropathy secondary to megadoses of vita...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198402000-00018
更新日期:1984-02-01 00:00:00
abstract::We describe a patient with pseudotumor cerebri for which a lumboperitoneal (LP) shunt was placed. After a pseudomeningocele was noted at the lumbar incision site, an LP shunt revision was done, at which time migration of the catheter into the thecal sac was noted. Three months later, radiologic studies revealed crania...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199606000-00019
更新日期:1996-06-01 00:00:00
abstract:OBJECTIVES:Clostridium difficile infection (CDI) is the most common healthcare-associated infection in the United States. Clinical practice guidelines for the treatment of CDI were updated in 2010 by the Society for Healthcare Epidemiology of America and the Infectious Diseases Society of America. An institutional guid...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000428
更新日期:2016-03-01 00:00:00
abstract::The experience of the Southern Regional Trophoblastic Disease Center includes 222 patients who were referred from January 1972 to October 1977. The initial tissue diagnosis was hydatidiform mole in 212 patients and choriocarcinoma in ten. There was spontaneous remission of 142 (69%) of the moles and one of the chorioc...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197811000-00006
更新日期:1978-11-01 00:00:00
abstract::The number of breast cancer survivors has increased and this increase is expected to continue, likely as a result of population and age growth, the implementation of earlier detection strategies, and the development of more effective therapies. Breast cancer treatment requires a multidisciplinary approach with surgery...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000000701
更新日期:2017-10-01 00:00:00
abstract::Disorders of the foregut are an increasingly common cause of symptoms in Western populations. This review summarizes recent advances in the understanding and treatment of gastroesophageal reflux disease, dyspepsia and celiac disease. ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000242808.91797.3d
更新日期:2007-03-01 00:00:00
abstract::Computed tomography is widely used to diagnose acute pancreatitis. Iodinated contrast medium lengthens the duration of pancreatitis and may increase the incidence of local or systemic complications. Total parenteral nutrition including IV lipid emulsion plays an important role in the management of patients with pancre...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000047667.00302.CD
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Tobacco use causes significant morbidity and mortality. Resident physicians at the George Washington University Medical Center are trained to counsel patients to stop smoking. METHODS:I retrospectively reviewed charts of 300 patients treated by resident physicians in the Department of Medicine (200) and the...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199910000-00007
更新日期:1999-10-01 00:00:00
abstract::Cardiac ascites is a rare condition. Diagnosis is aided by liver histology, which characteristically shows diffuse hepatic congestion affecting the centrilobular region. In our case of refractory ascites due to constrictive pericarditis, diagnosis was delayed because centribular hepatic congestion was absent histologi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199211000-00023
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVE:How outside factors affect physician decision making remains an open question of vital importance. We sought to investigate the importance of various influences on physician decision making when clinical guidelines differ from patient preference. METHODS:An online survey asking 469 primary care providers (PC...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000901
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine the prevalence of impairments relevant to upper extremity following breast cancer surgery and its impact on disability and health-related quality of life. METHODS:Sixty-seven female patients being treated with modified radical mastectomy or breast conserving surgery we...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181c38c41
更新日期:2010-01-01 00:00:00
abstract::Symptoms of hyperphosphatemia usually relate to the associated hypocalcemia. In a 33-year-old patient accidental infusion of a bolus of potassium phosphate (5 ml intravenously) was immediately followed by cardiac arrest. During CPR, clinically important hypocalcemia or hyperkalemia was not detected, but serum phosphor...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract::We report the case of an 18-year old man with hemolytic-uremic syndrome (HUS) having a classic clinical presentation and diagnostic renal pathology without evidence of microangiopathic hemolytic anemia (MAHA) by peripheral blood smear. Indirect evidence of hemolysis was suggested by mild anemia, elevation of serum lac...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199603000-00018
更新日期:1996-03-01 00:00:00
abstract::A patient had a tracheoesophageal fistula resulting from malignant histiocytoma. Surgical treatment included esophagectomy and repair of the left main-stem bronchus. Gastrointestinal continuity was restored by a right colon interposition after chemotherapy. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198409000-00044
更新日期:1984-09-01 00:00:00