Correction to: Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice.

abstract：:The administration of the anorexigenic drug d,l-fenfluramine (Ponderax) to laboratory animals results in a dose-dependent reduction in presynaptically located serotonergic reuptake transporter protein. This long-term effect may represent an altered mechanism of synthesis of the transporter (downregulation). Alternativ...

journal_title：Molecular neurobiology

authors： Westphalen RI,Dodd PR

更新日期：1995-08-01 00:00:00

abstract：:The identification of causative mutations in the (pro)granulin gene (GRN) has been a major breakthrough in the research on frontotemporal dementia (FTD). So far, all FTD-associated GRN mutations are leading to neurodegeneration through a "loss-of-function" mechanism, encouraging researchers to develop a growing number...

journal_title：Molecular neurobiology

authors： Kleinberger G,Capell A,Haass C,Van Broeckhoven C

更新日期：2013-02-01 00:00:00

abstract：:α-Synuclein, an abundant and conserved presynaptic brain protein, is implicated as a critical factor in Parkinson's disease (PD). The aggregation of α-synuclein is believed to be a critical event in the disease process. α-Synuclein is characterized by a remarkable conformational plasticity, adopting different conforma...

journal_title：Molecular neurobiology

authors： Berrocal R,Vasquez V,Rao Krs S,Gadad BS,Rao KS

更新日期：2015-01-01 00:00:00

abstract：:The use of statins for the prevention or treatment of different neurodegenerative diseases has generated considerable interest albeit with some controversy. Mechanisms of statin-induced neuroprotection are not well understood. Recently, we reported that simvastatin stimulated neuronal gene expression and protein level...

journal_title：Molecular neurobiology

authors： Butterick TA,Igbavboa U,Eckert GP,Sun GY,Weisman GA,Müller WE,Wood WG

更新日期：2010-06-01 00:00:00

abstract：:The transition from occasional to escalated psychostimulant use is accelerated by prior drug exposure. These behavioral observations may be related to long-lasting transcriptional and/or epigenetic changes induced by the drug pre-exposure. Herein, we investigated if a single methamphetamine (METH) injection would enha...

journal_title：Molecular neurobiology

authors： Jayanthi S,Torres OV,Ladenheim B,Cadet JL

更新日期：2020-03-01 00:00:00

abstract：:Up to now, survivin has been recommended as a prognostic and diagnostic indicator in glioma patients. However, there are still many controversies. Here, a meta-analysis was conducted to draw a more definitive conclusion on the correlation of survivin with overall survival (OS), age, gender, and WHO grade. Eligible stu...

journal_title：Molecular neurobiology

authors： Lv S,Dai C,Liu Y,Shi R,Tang Z,Han M,Bian R,Sun B,Wang R

更新日期：2015-01-01 00:00:00

abstract：:There is accumulating evidence on the use of N-acetylcysteine (NAC) in the treatment of patients with neuropsychiatric disorders. As a multi-target drug and a glutathione precursor, NAC is a promising molecule in the management of stress-related disorders, for which there is an expanding field of research investigatin...

journal_title：Molecular neurobiology

authors： Mocelin R,Marcon M,D'ambros S,Mattos J,Sachett A,Siebel AM,Herrmann AP,Piato A

更新日期：2019-02-01 00:00:00

abstract：:OMI/HTRA2 (high-temperature requirement serine protease A2) is a mitochondrial serine protease involved in several cellular processes, including autophagy, chaperone activity, and apoptosis. Few studies on the role of OMI/HTRA2 in Alzheimer's disease (AD) are available, but none on its relationship with the cholinergi...

journal_title：Molecular neurobiology

authors： Darreh-Shori T,Rezaeianyazdi S,Lana E,Mitra S,Gellerbring A,Karami A,Bogdanovic N,Lithner CU,Winblad B,Behbahani H

更新日期：2019-07-01 00:00:00

abstract：:Activated autophagy/mitophagy has been intensively observed in ischemic brain, but its roles remain controversial. Peroxynitrite (ONOO-), as a representative of reactive nitrogen species, is considered as a critical neurotoxic factor in mediating cerebral ischemia-reperfusion (I/R) injury, but its roles in autophagy/m...

journal_title：Molecular neurobiology

authors： Feng J,Chen X,Guan B,Li C,Qiu J,Shen J

更新日期：2018-08-01 00:00:00

abstract：:The discovery of α-synuclein has had profound implications concerning our understanding of Parkinson's disease (PD) and other neurodegenerative disorders characterized by α-synuclein accumulation. In fact, as compared with pre-α-synuclein times, a "new" PD can now be described as a whole-body disease in which a progre...

journal_title：Molecular neurobiology

authors： Ulusoy A,Di Monte DA

更新日期：2013-04-01 00:00:00

abstract：:Neuronal plasticity can be defined as adaptive changes in structure and function of the nervous system, an obvious example of which is the capacity to remember and learn. Long-term potentiation and long-term depression are the experimental models of memory in the central nervous system (CNS), and have been frequently ...

journal_title：Molecular neurobiology

authors： Tokuda M,Hatase O

更新日期：1998-01-01 00:00:00

abstract：:HIV infection and drugs of abuse induce oxidative stress and redox imbalance, which cause neurodegeneration. The mechanisms by which HIV infection and cocaine consumption affect astrocyte energy metabolism, and how this leads to neurodegenerative dysfunction, remain poorly understood. Presently, we investigated how ox...

journal_title：Molecular neurobiology

authors： Sivalingam K,Cirino TJ,McLaughlin JP,Samikkannu T

更新日期：2021-02-01 00:00:00

abstract：:Cell fate reprogramming makes possible the generation of new cell types from healthy adult cells to replace those lost or damaged in disease. Additionally, reprogramming patient cells into specific cell types allows for drug screening and the development of new therapeutic tools. Generation of new neurons is of partic...

journal_title：Molecular neurobiology

authors： Abdullah AI,Pollock A,Sun T

更新日期：2012-06-01 00:00:00

abstract：:Neurological dysfunction as a result of neuroinflammation has been reported in sepsis and cause high mortality. High levels of cytokines stimulate the formation of neurotoxic metabolites by kynurenine (KYN) pathway. Vitamin B6 (vit B6) has anti-inflammatory and antioxidant properties and also acts as a cofactor for en...

journal_title：Molecular neurobiology

authors： Danielski LG,Giustina AD,Goldim MP,Florentino D,Mathias K,Garbossa L,de Bona Schraiber R,Laurentino AOM,Goulart M,Michels M,de Queiroz KB,Kohlhof M,Rezin GT,Fortunato JJ,Quevedo J,Barichello T,Dal-Pizzol F,Coimbra RS,

更新日期：2018-06-01 00:00:00

abstract：:Maternal deprivation (MD) induces behavioral changes and impacts brain circuits that could be associated with the pathophysiology of depression. This study investigated the markers of microglia and astrocyte activation as well as indoleamine 2,3-dioxygenase (IDO) expression in developmental programming after early lif...

journal_title：Molecular neurobiology

authors： Réus GZ,Silva RH,de Moura AB,Presa JF,Abelaira HM,Abatti M,Vieira A,Pescador B,Michels M,Ignácio ZM,Dal-Pizzol F,Quevedo J

更新日期：2019-02-01 00:00:00

abstract：:Phospholipase C beta 1 (PLCβ1) expresses in gliomas and cultured glial cells, but its expression is barely detectable in normal glial cells. We analyzed data from Gene Expression Omnibus (GEO-GDSxxx), The Cancer Genome Atlas (TCGA), and the Repository for Molecular Brain Neoplasia Data (REMBRANDT) to explore the poten...

journal_title：Molecular neurobiology

authors： Lu G,Chang JT,Liu Z,Chen Y,Li M,Zhu JJ

更新日期：2016-11-01 00:00:00

abstract：:Neonatal hypoxia-ischemia (HI) is among the main causes of mortality and morbidity in newborns. Experimental studies show that the immature rat brain is less susceptible to HI injury, suggesting that changes that occur during the first days of life drastically alter its susceptibility. Among the main developmental cha...

journal_title：Molecular neurobiology

authors： Odorcyk FK,Ribeiro RT,Roginski AC,Duran-Carabali LE,Couto-Pereira NS,Dalmaz C,Wajner M,Netto CA

更新日期：2021-01-08 00:00:00

abstract：:Rett syndrome is a complex neurodevelopmental disorder that is mainly caused by mutations in MECP2. However, mutations in FOXG1 cause a less frequent form of atypical Rett syndrome, called FOXG1 syndrome. FOXG1 is a key transcription factor crucial for forebrain development, where it maintains the balance between prog...

journal_title：Molecular neurobiology

authors： Weise SC,Arumugam G,Villarreal A,Videm P,Heidrich S,Nebel N,Dumit VI,Sananbenesi F,Reimann V,Craske M,Schilling O,Hess WR,Fischer A,Backofen R,Vogel T

更新日期：2019-07-01 00:00:00

abstract：:Mammalian brain contains high densities of angiotensin II (Ang II) type 1 (AT1) receptors, localized mainly to specific nuclei within the hypothalamus and brainstem regions. Neuronal AT1 receptors within these areas mediate the stimulatory actions of central Ang II on blood pressure, water and sodium intake, and vasop...

journal_title：Molecular neurobiology

authors： Richards EM,Raizada MK,Gelband CH,Sumners C

更新日期：1999-02-01 00:00:00

abstract：:Since the discovery of leptin and the central melanocortin circuit, electrophysiological studies have played a major role in elucidating mechanisms underlying energy homeostasis. This review highlights the contribution of findings made by electrophysiological measurements to the current understanding of hypothalamic n...

journal_title：Molecular neurobiology

authors： Ghamari-Langroudi M

更新日期：2012-04-01 00:00:00

abstract：:Endozepine has recently been isolated from various steroid-forming organs. The following article explores the role of endozepine in the regulation of steroid synthesis. Steroid hormone synthesis from cholesterol begins in the inner mitochondrial membrane, where cytochrome P450 converts cholesterol to pregnenolone. Sci...

journal_title：Molecular neurobiology

authors： Hall PF

更新日期：1995-02-01 00:00:00

abstract：:Long-term potentiation (LTP) is a cellular model for learning and memory and believed to be critical for plastic changes in the brain. Depending on the central nervous system region, LTP has been proposed to contribute to many key physiological functions and pathological conditions, such as learning/memory, chronic pa...

journal_title：Molecular neurobiology

authors： Descalzi G,Kim S,Zhuo M

更新日期：2009-12-01 00:00:00

abstract：:Insulin receptors in the brain are found in high densities in the hippocampus, a region that is fundamentally involved in the acquisition, consolidation, and recollection of new information. Using the intranasal method, which effectively bypasses the blood-brain barrier to deliver and target insulin directly from the ...

journal_title：Molecular neurobiology

authors： Schiöth HB,Craft S,Brooks SJ,Frey WH 2nd,Benedict C

更新日期：2012-08-01 00:00:00

abstract：:Thyroid hormone plays an important role in central nervous system (CNS) development, including the myelination of variable axonal calibers. It is well-established that thyroid hormone is required for the terminal differentiation of oligodendrocyte precursor cells (OPCs) into myelinating oligodendrocytes by inducing ra...

journal_title：Molecular neurobiology

authors： Lee JY,Petratos S

更新日期：2016-11-01 00:00:00

abstract：:Although photobiomodulation therapy (PBM) has been applied clinically for the treatment of pain and inflammation, wound healing, sports and soft tissue injuries, as well as to repair injured spinal cords and peripheral nerves, it remains unclear which molecular substrates (receptor) are implicated in the cellular mech...

journal_title：Molecular neurobiology

authors： Neves LMS,Gonçalves ECD,Cavalli J,Vieira G,Laurindo LR,Simões RR,Coelho IS,Santos ARS,Marcolino AM,Cola M,Dutra RC

更新日期：2018-07-01 00:00:00

abstract：:The question of how the cell surface molecules may be specifically delivered to subdomains of neurons is of particular interest considering that polarized sorting to the axon could enable adhesion glycoproteins to induce fasciculation of axonal tracts, guidance to the target cell, and the establishment of synaptic con...

journal_title：Molecular neurobiology

authors： Faivre-Sarrailh C,Rougon G

更新日期：1993-04-01 00:00:00

abstract：:Recent evidence suggests that hypoxia preconditioning can alter the microRNA (miRNA) profile of extracellular vesicles (EVs) and has better neuroprotective effects when enriched miRs are delivered to recipients. However, the roles of exosomal miRNAs in regulating ischaemia-reperfusion (IR)-induced pain hypersensitivit...

journal_title：Molecular neurobiology

authors： Wang H,Chen FS,Zhang ZL,Zhou HX,Ma H,Li XQ

更新日期：2021-02-01 00:00:00

abstract：:Despite the increasing evidence of eye abnormalities, the effects of prenatal exposure to cocaine on the visual system are still poorly understood. This study was aimed at analyzing the qualitative and quantitative organization of the retinal photoreceptor cells (PR) and outer nuclear layer (ONL) after prenatal exposu...

journal_title：Molecular neurobiology

authors： Silva-Araújo A,Abreu-Dias P,Silva MC,Tavares MA

更新日期：1995-08-01 00:00:00

abstract：:Stress, unaccompanied by signs of post-traumatic stress disorder, is known to decrease grey matter volume (GMV) in the anterior cingulate cortex (ACC) and hippocampus but not the amygdala in humans. We sought to determine if this was the case in stressed mice using high-resolution magnetic resonance imaging (MRI) and ...

journal_title：Molecular neurobiology

authors： Kassem MS,Lagopoulos J,Stait-Gardner T,Price WS,Chohan TW,Arnold JC,Hatton SN,Bennett MR

更新日期：2013-04-01 00:00:00

abstract：:It has recently been reported that the phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling pathway regulates neuronal differentiation of neural stem cells (NSCs) derived from rats or mice and is essential for the self-renewal of human embryonic stem cells (hESCs). However, the roles of ...

journal_title：Molecular neurobiology

authors： Lee JE,Lim MS,Park JH,Park CH,Koh HC

更新日期：2016-08-01 00:00:00