Immune response to Fc tagged GP5 glycoproteins of porcine reproductive and respiratory syndrome virus.

abstract：:In the developing countries, Hepatitis E virus (HEV) is a predominant cause of sporadic acute hepatitis in adults and waterborne epidemics leading to high mortality in pregnant women. Vaccine development mainly focuses on the structural capsid protein open-reading-frame-2 (ORF-2) of the virus. We successfully evaluate...

journal_title：Viral immunology

authors： Joshi SS,Arankalle VA

更新日期：2016-07-01 00:00:00

abstract：:Chemokine receptors CXCR4 and CCR5 play a key role in Human Immunodeficiency Virus (HIV) entry into CD4+ monocytic cells. Alteration in the expression levels of these receptors by immunoregulatory cytokines may influence viral entry and hence susceptibility to HIV infection, viral tropism, and disease progression. Hel...

journal_title：Viral immunology

authors： Creery D,Weiss W,Graziani-Bowering G,Kumar R,Aziz Z,Angel JB,Kumar A

更新日期：2006-07-01 00:00:00

abstract：:Enterovirus infections may be involved in the etiology of type 1 diabetes (T1D), which is strongly associated with certain human leukocyte antigen (HLA) class II haplotypes. Our aim was to assess whether HLA genotypes conferring varying degrees of risk for T1D were associated with enterovirus gut infections. From the ...

journal_title：Viral immunology

authors： Witsø E,Cinek O,Tapia G,Rasmussen T,Stene LC,Rønningen KS

更新日期：2012-06-01 00:00:00

abstract：:Severe acute respiratory syndrome (SARS) is a deadly and highly infectious disease caused by SARS Coronavirus (SARS-CoV). Inactivated SARS-CoV has been explored as a vaccine against SARS-CoV; however, current knowledge of inactivated SARS-CoV vaccine is quite limited. We attempted to investigate the effects of differe...

journal_title：Viral immunology

authors： Gai W,Zou W,Lei L,Luo J,Tu H,Zhang Y,Wang K,Tien P,Yan H

更新日期：2008-03-01 00:00:00

abstract：:Altered cytokine transcription might play an important role in the pathogenesis of human immunodeficiency virus (HIV) infection in humans. The infection of rhesus macaques with simian immunodeficiency virus (SIV) provides a relevant animal model for HIV infection. Therefore, we evaluated the cyokine transcription of p...

journal_title：Viral immunology

authors： Spring M,Bodemer W,Stahl-Hennig C,Nisslein T,Hunsmann G,Dittmer U

更新日期：1997-01-01 00:00:00

abstract：:Infusion of interleukin-12 (IL-12) enhances recovery from lethal experimental vesicular stomatitis virus (VSV) infection of the central nervous system (CNS). Interleukin-12 treatment resulted in: 1) increased survival frequency; 2) faster recovery from weight loss; 3) substantially decreased VSV titers in brain homoge...

journal_title：Viral immunology

authors： Komatsu T,Barna M,Reiss CS

更新日期：1997-01-01 00:00:00

abstract：:Subjects > or = 55 years of age were immunized with attenuated varicella zoster virus (VZV) vaccine (live) or with the same vaccine, which had been heated to 56 degrees C for 7 days (killed). The ability of subjects' blood lymphocytes to lyse target cells infected with VZV was determined before and 3 months after immu...

journal_title：Viral immunology

authors： Hayward AR,Buda K,Jones M,White CJ,Levin MJ

更新日期：1996-01-01 00:00:00

abstract：:Previously, we have shown that bovine herpesvirus 1 (BHV-1) down-regulates the expression of major histocompatibility complex class I molecules by interfering with transport of peptides by the transporter associated with antigen processing (TAP). Further studies revealed that BHV-1 down-regulates the expression of mRN...

journal_title：Viral immunology

authors： Gopinath RS,Ambagala AP,Hinkley S,Srikumaran S

更新日期：2002-01-01 00:00:00

abstract：:Interferon (IFN) can activate Signal Transducer and Activator of Transcription (STAT) proteins to establish a cellular antiviral response and inhibit virus replication. Many viruses have evolved strategies to inhibit this antiviral mechanism, but paramyxoviruses are unique in their abilities to directly target the IFN...

journal_title：Viral immunology

authors： Rodriguez JJ,Horvath CM

更新日期：2004-01-01 00:00:00

abstract：:Essen regimen, the Thai Red Cross two-site ID regimen, Zagreb schedule, and the eight-site ID regimen are the standard rabies vaccines recommended by the World Health Organization (WHO). In this study, a liposomal rabies vaccine (LipoRV) was developed, which was found to facilitate the production of rabies virus neutr...

journal_title：Viral immunology

authors： Miao L,Yang Y,Yan M,Li Y,Zhao J,Guo J,Zheng D

更新日期：2017-12-01 00:00:00

abstract：:TransFix(TM) and Cyto-Chex((R)) BCT (blood collection tube) reagents have been shown to maintain whole blood integrity for delayed immunophenotyping by flow cytometry. We evaluated the ability of these blood-stabilizing reagents to preserve HIV-seropositive blood for delayed CD4(+) T-cell quantification utilizing the ...

journal_title：Viral immunology

authors： Plate MM,Louzao R,Steele PM,Greengrass V,Morris LM,Lewis J,Barnett D,Warrino D,Hearps AC,Denny T,Crowe SM

更新日期：2009-10-01 00:00:00

abstract：:Abstract Influenza virus nucleoprotein (NP) binds to the viral genome RNA and forms the internal ribonucleoprotein complex of the virus particle. Avian and human influenza virus NP have characteristic differences at several amino acid positions. It is not known whether any of these differences can be recognized by ant...

journal_title：Viral immunology

authors： Varich NL,Sadykova GK,Prilipov AG,Kochergin-Nikitsky KS,Kushch AA,Masalova OV,Klimova RR,Gitelman AK,Kaverin NV

更新日期：2011-04-01 00:00:00

abstract：:Hepatitis C virus (HCV) signifies an important health issue as it is a globally prevalent pathogen and poses a great threat to human health. Direct antiviral therapy became a landmark in treatment against chronic HCV infection as they have proven to increase sustained virological response (SVR) rate, provide shortened...

journal_title：Viral immunology

authors： Aziz H,Aziz M,Gill ML

更新日期：2018-04-01 00:00:00

abstract：:Sera from 1003 in- and out-patients were investigated for hepatitis B surface antigen (HBsAg) mutation at Siriraj Hospital, Bangkok, Thailand. Individual samples were screened using two commercial HBsAg kits on automatic machine-based assays set up in parallel. The first kit was a sandwich ELISA kit that used monoclon...

journal_title：Viral immunology

authors： Louisirirotchanakul S,Kanoksinsombat C,Theamboonlert A,Puthavatana P,Wasi C,Poovorawan Y

更新日期：2004-01-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) continues to be an economically important infectious disease of swine. Mechanisms governing activation of the innate immune response to PRRSV remain to be elucidated. Virulence differences observed between PRRSV isolates have been attributed to replication ab...

journal_title：Viral immunology

authors： Loving CL,Brockmeier SL,Vincent AL,Lager KM,Sacco RE

更新日期：2008-09-01 00:00:00

abstract：:Infection of porcine alveolar macrophages by the porcine reproductive and respiratory syndrome virus (PRRSV) was significantly enhanced in vitro by antibody raised against the PRRSV isolate ISU-P (p < 0.01). Increased yields and infection rates were highly correlated (r = 0.95) and the ratio of yield to infection rate...

journal_title：Viral immunology

authors： Yoon KJ,Wu LL,Zimmerman JJ,Hill HT,Platt KB

更新日期：1996-01-01 00:00:00

abstract：:Fowl aviadenoviruses (FAdVs) are distributed worldwide in poultry farms. Some FAdVs are the causative agents of inclusion body hepatitis and hydropericardium syndrome that cause significant economic losses to the poultry industry. In contrast with human adenovirus, the study of the molecular biology of FAdV is still f...

journal_title：Viral immunology

authors： Deng L,Griffin BD,Pei Y,Leishman D,McBey BA,Sharif S,Nagy É

更新日期：2017-11-01 00:00:00

abstract：:HIV infection is characterized by a high degree of immune activation. It has an impact on CD4 cell count and populations' distribution and function. T regulatory cells (Tregs) were found to play a controversial role in the course of infection because of their beneficial effect on the degree of immune activation and un...

journal_title：Viral immunology

authors： Terzieva VI,Popova DN,Elenkov II

更新日期：2017-04-01 00:00:00

abstract：:CD3+CD8+CD11+ cells were present in the peripheral blood of patients infected with asymptomatic human immunodeficiency virus (HIV) in higher percentage (10-20%) than in normal individuals (3-5%) in this study. These cells, through the release of soluble factors, significantly suppressed the effector phase of anti-HIV ...

journal_title：Viral immunology

authors： Kundu SK,Merigan TC

更新日期：1992-04-01 00:00:00

abstract：:This study is an improvement on the antibody binding test, known as ABT method, to develop a simple and fast method in comparison with NIH for determination of rabies vaccine potency. In the current study, several commercial human and veterinary vaccines were tested using both modified ABT and NIH methods. The ED50 wa...

journal_title：Viral immunology

authors： Asgary V,Mojtabavi N,Janani A,Mousavi T,Hadjati J,Khosravy MS,Ahangari Cohan R

更新日期：2017-04-01 00:00:00

abstract：:Mice depleted in vivo of either CD4+ or CD8+ T cells were used to define the requirement for interaction between the two T subsets for the induction and maturation of a herpes simplex virus (HSV) cytotoxic T-lymphocyte (CTL) response. Whereas C3H mice generated normal CD8+ CTL in the absence of CD4+ T cells, responses...

journal_title：Viral immunology

authors： Mercadal CM,Martin S,Rouse BT

更新日期：1991-10-01 00:00:00

abstract：:The involvement of retroviruses in the etiopathogenesis of autoimmunity is discussed. Recently antibodies against p24 of HIV-1 were described in patients from Texas with SLE. Therefore we investigated the presence of these antibodies in our SLE collective (German caucasians and blacks from Michigan) employing ELISA an...

journal_title：Viral immunology

authors： Herrmann M,Baur A,Nebel-Schickel H,Vornhagen R,Jahn G,Krapf FE,Kalden JR

更新日期：1992-10-01 00:00:00

abstract：:The VP1 represents the major capsid protein of the hamster polyomavirus (HaPV). Here we describe the mapping of epitopes along the VP1 using Escherichia coli-expressed VP1-dihydrofolate reductase (DHFR) fusion proteins and PepScan analysis. By use of DHFR fusion proteins an immunodominant region was localized in the C...

journal_title：Viral immunology

authors： Siray H,Frömmel C,Voronkova T,Hahn S,Arnold W,Schneider-Mergener J,Scherneck S,Ulrich R

更新日期：2000-01-01 00:00:00

abstract：:This study was aimed at investigating the genes that control host responses to Marek's disease virus (MDV). Spleen tissues from infected and age-matched uninfected control chickens were examined 4, 7, 14, and 21 d postinfection for gene expression differences, using both microarray and quantitative real-time polymeras...

journal_title：Viral immunology

authors： Sarson AJ,Abdul-Careem MF,Zhou H,Sharif S

更新日期：2006-01-01 00:00:00

abstract：:Anti-idiotypic antibodies (Ab2) binding to the antigen-combining site of other antibodies may functionally and even structurally mimic antigen. Ab2 to antibodies directed against the lymphocyte CD4 receptor for human immunodeficiency virus type 1 (HIV-1) may mimic the receptor and therefore inhibit viral infectivity. ...

journal_title：Viral immunology

authors： Liang SH,Rieber P,Prewett M,Riethmüller G,Pletcher C,Hoxie J,Koprowski H,Herlyn D

更新日期：1991-07-01 00:00:00

abstract：:To study IgG-specific subclasses of hepatitis B virus (HBV) surface antigen (anti-HBs), in different populations in Taiwan, a comparison was made between 104 chronic carriers (60 male and 44 female) and 439 recovered individuals (247 male and 192 female). Biochemical analyses of aspartate aminotransferase (AST) and al...

journal_title：Viral immunology

authors： Tsai TH,Huang CF,Wei JC,Ho MS,Wang L,Tsai WY,Lin CC,Xu FL,Yang CC

更新日期：2006-07-01 00:00:00

abstract：:This study was to evaluate the immunostimulatory effects of N-(2-hydroxy) propyl-3-trimethylammonium chitosan chloride (HTCC) as an adjuvant for improving a commercial live attenuated hepatitis A virus (HAV) vaccine efficacy in mice. Mice in the experimental group were intraperitoneally immunized with a solution of HT...

journal_title：Viral immunology

authors： Tao W,Fu T,He Z,Hu R,Jia L,Hong Y

更新日期：2017-03-01 00:00:00

abstract：:Abstract Natural infection with Marek's disease virus occurs through the respiratory mucosa after chickens inhale dander shed from infected chickens. The early events in the lung following exposure to the feather and squamous epithelial cell debris containing the viral particles remain unclear. In order to elucidate t...

journal_title：Viral immunology

authors： Baaten BJ,Staines KA,Smith LP,Skinner H,Davison TF,Butter C

更新日期：2009-12-01 00:00:00

abstract：:Most strategies for reducing global measles morbidity and mortality and eliminating measles are based on the ability to enhance immune responses to measles virus. Challenges to measles elimination and eradication are based in part on the need to sustain high levels of population immunity to interrupt transmission of m...

journal_title：Viral immunology

authors： Moss WJ,Polack FP

更新日期：2001-01-01 00:00:00

abstract：:Regulatory/suppressor cells have become rehabilitated and respectable. They returned as regulators of autoimmunity, but are now acknowledged to critically influence immunity to foreign antigens, such as those found on microbes. This review describes the principal types of regulatory cells that influence immunity to mi...

journal_title：Viral immunology

authors： Suvas S,Rouse BT

更新日期：2005-01-01 00:00:00