Abstract:
:Hereditary hemoglobin disorders affecting the globin chain synthesis namely thalassemia syndromes and sickle cell disease (SCD) are the most common genetic disorders in human. Around 7% of the world population carries genes for these disorders, mainly the Mediterranean Basin, Middle and Far East, and Sub-Saharan Africa. An estimated 30 million people worldwide are living with sickle cell disease, while 60-80 million carry beta thalassemia trait. About 400,000 children are born with severe hemoglobinopathies each year. Cardiovascular complications of hemoglobinopathies include left and right ventricular (RV) dysfunction, arrhythmias, pericarditis, myocarditis, valvular heart disease, myocardial ischemia, and notably pulmonary hypertension (PH). Because of a unique pathophysiology, pulmonary hypertension associated with hemolytic disorders was moved from WHO group I to group V PH diseases. Treatment strategies are also unique and include blood transfusion, iron chelation, hydroxyurea, and oxygen therapy. The role of PH-specific agents has not been established.
journal_name
Ann Thorac Medjournal_title
Annals of thoracic medicineauthors
Saleemi Sdoi
10.4103/1817-1737.134039subject
Has Abstractpub_date
2014-07-01 00:00:00pages
S67-73issue
Suppl 1eissn
1817-1737issn
1998-3557pii
ATM-9-67journal_volume
9pub_type
杂志文章abstract:AIM:The aim of this study was to investigate the alterations of pulmonary function tests (PFTs) and their relationship with disease activity in inflammatory bowel diseases (IBDs). METHODS:Sixty-four IBD patients (31 Crohn's disease [CD] and 33 ulcerative colitis [UC]) and thirty healthy individuals (controls) were stu...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.191877
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:For patients that are expected to survive for longer, the risk of complications combined with the need for more vacuum drainage bottles have become barriers to the placement of indwelling pleural catheter (IPC), since these could increase costs. OBJETIVES:The objective of the current article is to determine...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.160837
更新日期:2015-07-01 00:00:00
abstract:AIMS:Flexible bronchoscopy is a common procedure performed in pulmonary medicine, critical care, and thoracic surgery. In this study, we aimed to assess the prevalence and predictors of anxiety in patients undergoing diagnostic bronchoscopy. METHODS:This is a prospective study conducted at King Abdulaziz University Ho...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_38_19
更新日期:2019-07-01 00:00:00
abstract::Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) pneumonia is associated with very high mortality. Though surgical evacuation of necrotic tissue is desirable in patients unresponsive to antimicrobial therapy, most patients are acutely ill precluding surgical intervention. We utilized a combinat...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.164298
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:There is limited data about the performance of QuantiFERON-TB Gold (QFT-G) test in detecting latent tuberculosis infection (LTBI) in our region. We intended to determine the performance of QFT-G compared to conventional tuberculin skin test (TST) in detecting LTBI in HIV-positive individuals in Iran. METHOD...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.58959
更新日期:2010-01-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.109818
更新日期:2013-04-01 00:00:00
abstract::Novel coronavirus disease 2019 (COVID-19) is known to cause severe pneumonia and acute respiratory distress syndrome which may lead to death. Several treatments have been tested in the race to find a treatment regimen for this deadly viral infection. Tocilizumab, a recombinant humanized anti-interleukin-6 receptor mon...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/atm.ATM_286_20
更新日期:2020-07-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.74275
更新日期:2011-01-01 00:00:00
abstract::Chronic cough is associated with repetitive injury to the upper airway and trachea, which can lead to an underdiagnosed pathology known as "cough-induced" laryngotracheitis (CILT). In this report, we describe a case of CILT that responded well to dual therapy. ...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/atm.ATM_21_18
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Pulmonary rehabilitation (PR) programs proven to be one of the most effective treatment options for respiratory diseases; yet, they are not well-established in hospitals in Saudi Arabia. AIM:To determine the main barriers for setting up PR programs in Saudi Arabia. METHODS:A cross-sectional study was condu...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.180028
更新日期:2016-04-01 00:00:00
abstract::A 12-hour-old male infant presented with prolapsed abdominal content through a defect on left side of chest wall with respiratory distress. A thorough clinical examination suggested absence of ectopia cordis, abdominal wall defect, and any bony anomaly. The child expired after 6 hours of admission because of respirato...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.41916
更新日期:2008-07-01 00:00:00
abstract::Bronchiolitis obliterans organizing pneumonia (BOOP) was first described in the early 1980s as a clinicopathologic syndrome characterized symptomatically by subacute or chronic respiratory illness and histopathologically by the presence of granulation tissue in the bronchiolar lumen, alveolar ducts and some alveoli, a...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.39641
更新日期:2008-04-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_264_19
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:The IL-4 receptor alpha subunit (IL-4Rα), when associated with the common gamma chain receptor, or the IL-13Rα1 subunit, transduces signals to STAT6 in response to IL-4 and IL-13 stimulations. This results in a number of cell-specific responses including Th2 differentiation, lymphocyte proliferation and IgE ...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.128849
更新日期:2014-04-01 00:00:00
abstract:INTRODUCTION:Fiber-optic bronchoscopy (FOB) with bronchoalveolar lavage (BAL) is a common procedure performed in immunocompromised patients with undiagnosed pulmonary pathology. Identifying patients with the highest potential diagnostic yield may help to avoid morbidity in patients unlikely to benefit from the procedur...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.114302
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the association between epidermal growth factor receptor (EGFR) mutation and thyroid cancer in female patients with nonsmall-cell lung cancer (NSCLC). METHODS:In a retrospective study, we examined 835 female patients who were diagnosed with NSCLC and underwent an EGF...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.197774
更新日期:2017-01-01 00:00:00
abstract::The Saudi Initiative for Asthma (SINA) provides up-to-date guidelines for healthcare workers managing patients with asthma. SINA was developed by a panel of Saudi experts with respectable academic backgrounds and long-standing experience in the field. SINA is founded on the latest available evidence, local literature,...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.56001
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Videothoracoscopic surgery leads to general organ hypoperfusion by reducing mean arterial pressure, systemic vascular resistance, and end-diastolic volume index. Oxidative stress occurs as a result of hypoperfusion. Evaluation of the short-term effects of videothoracoscopic sympathectomy on serum ischemia-mo...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.172298
更新日期:2016-01-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.118480
更新日期:2013-10-01 00:00:00
abstract::NASAM (National Approach to Standardize and Improve Mechanical Ventilation) is a national collaborative quality improvement project in Saudi Arabia. It aims to improve the care of mechanically ventilated patients by implementing evidence-based practices with the goal of reducing the rate of ventilator-associated event...
journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_63_19
更新日期:2019-04-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章,评审
doi:10.4103/1817-1737.160365
更新日期:2015-10-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.53346
更新日期:2009-07-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.185761
更新日期:2016-07-01 00:00:00
abstract::We report a case of bronchial Dieulafoy's disease in the pediatric age. Angio-computed tomography scan and arteriography addressed us to diagnosis. Bronchial endoscopy with biopsy was avoided due to the high risk of developing a life-threatening hemorrhage. Transcatheter embolization of the bleeding bronchial artery w...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/atm.ATM_163_20
更新日期:2020-10-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.30357
更新日期:2007-01-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.152450
更新日期:2015-04-01 00:00:00
abstract::Swyer-James-MacLeod (SJM) syndrome is a chronic, progressive lung disease as a result of infection and bronchial obstruction that ultimately leads to emphysema. It is associated with chronic cough, sputum production and recurrent chest infections and is occasionally seen in women of reproductive age. The radiological ...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.37976
更新日期:2008-01-01 00:00:00
abstract::We report a case of pulmonary strongyloidiasis in a patient with large granular lymphocytosis. He was on short-term high dose immunosuppressant therapy. A 77-year-old white male presented to the emergency room with fever and shortness of breath for 10 days. The patient had been diagnosed about 3 months prior to this p...
journal_title:Annals of thoracic medicine
pub_type:
doi:10.4103/1817-1737.78432
更新日期:2011-04-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/atm.ATM_26_19
更新日期:2019-10-01 00:00:00
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journal_title:Annals of thoracic medicine
pub_type: 杂志文章
doi:10.4103/1817-1737.82436
更新日期:2011-07-01 00:00:00