Abstract:
:Gelatin nanoparticles can be stabilized by entrapping them in Eudragit E100 nanospheres. The size of the nanospheres was dependent on the homogenization speed, producing nanospheres of 433 nm (8000 rpm) and 176 nm (15000 rpm). The nanoparticle morphology was critically dependent on Eudragit E100 concentration; with 2% Eudragit E 100 nanospheres showed spherical depressions (pores) of around 90 nm on the surface. The number of porous particles decreased from 68% to 5% when Eudragit1 E 100 concentration was increased to 6%, which in turn improved gelatin entrapment from 55% to 93% respectively. Additionally, the initial burst release of gelatin was decreased from 30% to 10% respectively.
journal_name
Macromol Bioscijournal_title
Macromolecular bioscienceauthors
Khan SA,Schneider Mdoi
10.1002/mabi.201400214subject
Has Abstractpub_date
2014-11-01 00:00:00pages
1627-38issue
11eissn
1616-5187issn
1616-5195journal_volume
14pub_type
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