Abstract：
:This review focuses on the contribution of abnormal blood rheology in the pathophysiology of sickle cell anemia (SCA). SCA is characterized by a reduction of red blood cell (RBC) deformability but this reduction is very heterogeneous among patients. Recent works have shown that patients with the lowest RBC deformability (measured by ektacytometry) have enhanced hemolysis and would be more prone to develop several complications such as priapism, leg ulcers and glomerulopathy. In contrast, patients with the highest deformability, and not under hydroxyurea therapy, seem to develop more frequently vaso-occlusive like events. Although less studied, RBC aggregation properties are very different between SCA and healthy individuals and it was demonstrated that increased RBC aggregates strength could be involved in some complications. Finally, several studies have established that the vascular system of SCA patients could not fully compensate any increase in blood viscosity because of the loss of vascular reactivity, which may result in vaso-occlusive crises.
journal_name
Clin Hemorheol Microcircjournal_title
Clinical hemorheology and microcirculationauthors
Connes P,Renoux C,Romana M,Abkarian M,Joly P,Martin C,Hardy-Dessources MD,Ballas SKdoi
10.3233/CH-189005subject
Has Abstractpub_date
2018-01-01 00:00:00pages
165-172issue
2-3eissn
1386-0291issn
1875-8622pii
CH189005journal_volume
68pub_type
杂志文章abstract：INTRODUCTION:Laparoscopy is more beneficial than the conventional open technique, however the pneumoperitoneum created may have an ischemic side effect. OBJECTIVE:Our aim was to evaluate the protective effects of preconditioning during laparoscopic cholecystectomies (LC). METHODS:30 patients were randomized into 2 gr...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-170336
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to analyse the effects of dance movement therapy exercises (DMT) on the rheological properties of blood in elderly women. METHODS:The study encompassed group of women (mean aged: 67 years), who were subjected to three-month dance movement therapy programme (n = 20). Blood samples fr...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-180470
更新日期：2019-01-01 00:00:00
abstract：:Haemorheological parameters in nine breeds of dog were examined. Whole blood viscosity at both high and low shear rates differed significantly between the breeds with a 50% difference between the highest and lowest viscosity at high shear rate and a 140% difference at low shear rate. Athletic breeds (Greyhounds, Deerh...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：BACKGROUND:Purpura fulminans (PF) is a distinct form of rare meningococcal septicaemia mostly in childhood which is characterized by high lethality, extensive necroses and mutilations of extremities. Other ethiologies are idiopathic forms or purpura neonatorum, which is marked by deficiency of Protein-C. PF is caused b...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-190588
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Autologous blood doping (ABD) is applied to improve performance capacity. ABD includes blood donation, red blood cell (RBC) storage at -80°C and re-infusion prior to or during competition. ABD is not directly detectable with current detection techniques. OBJECTIVE:Since cryopreservation is known to affect R...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-200887
更新日期：2020-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-180453
更新日期：2020-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-2011-1417
更新日期：2011-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-168017
更新日期：2016-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-2012-1532
更新日期：2012-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Nitric oxide (NO) has a role in the pathophysiology of acute and chronic cardiovascular events. We studied the plasma concentration of NO stable end products (nitrite and nitrate--NOx) in 43 patients aged<46 years, with recent acute myocardial infarction (AMI). The evaluation was effected at the initial stage, after 3...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-179103
更新日期：2017-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-2010-1330
更新日期：2010-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-2012-1618
更新日期：2013-01-01 00:00:00
abstract：:In this study, the effect of the angiotensin-converting-enzyme inhibitor (ACE inhibitor) Ramipril (5 mg/day) and calcium antagonist Isradipin (5 mg/day) treatment of two groups of hypertensive patients (n = 22 in each of group) was evaluated. The parameters of the hemorheological profile (blood and plasma viscosity, r...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：:We studied the effect of mechanical forces (shear stress) on the kinetics of internalization of native LDL and ox-LDL in endothelial cell line ECV304. This study was performed by using Confocal microscopy and FRET with two carbocyanine dyes, 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (DiO) as t...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-2009-1230
更新日期：2009-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-168027
更新日期：2016-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-2010-1367
更新日期：2011-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-2010-1371
更新日期：2011-01-01 00:00:00
abstract：PURPOSE:Obstructive diseases of the salivary glands are often based on Sialolithiasis; however, conventional radiological imaging or ultrasound does not provide a diagnosis in 5-10% of all cases. It was the aim of our study to examine the effectiveness and viability of an intraductal applied contrast-enhanced ultrasoun...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-2010-1298
更新日期：2010-01-01 00:00:00
abstract：:The contribution of hemorheological alterations in the prothrombotic condition in patients with metabolic syndrome (MS) remains a question of debate. We aimed to determine the association between MS and hemorheological parameters by means of a case-control study in 61 MS patients and 89 controls without MS. We determi...
journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-2011-1499
更新日期：2011-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-141843
更新日期：2015-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
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doi：10.3233/CH-2012-1594
更新日期：2012-01-01 00:00:00
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journal_title：Clinical hemorheology and microcirculation
pub_type： 杂志文章
doi：10.3233/CH-141833
更新日期：2015-01-01 00:00:00
