Isoflurane-induced neuronal apoptosis in developing hippocampal neurons.

abstract：:Three male patients were diagnosed with new cortical infarctions of the right parietal lobe on the basis of head magnetic resonance imaging; high-intensity signals indicating lesions in the right parietal lobe were noted on diffusion-weighted images at admission. Two of them presented with left hand weakness, and one ...

journal_title：Neural regeneration research

authors： Li F,Jia Y

更新日期：2012-04-25 00:00:00

abstract：:As a neuroprotective drug for the treatment of ischemic stroke, 3-n-butylphthalide, a celery seed extract, has been approved by the State Food and Drug Administration of China as a clinical therapeutic drug for ischemic stroke patients. L-3-n-butylphthalide possesses significant efficacy in the treatment of acute isch...

journal_title：Neural regeneration research

authors： Huai Y,Dong Y,Xu J,Meng N,Song C,Li W,Lv P

更新日期：2013-07-05 00:00:00

abstract：:Injury to axons close to the neuronal bodies in the mammalian central nervous system causes a large proportion of parenting neurons to degenerate. It is known that optic nerve transection close to the eye in rodents leads to a loss of about half of retinal ganglion cells in 1 week and about 90% in 2 weeks. Using low l...

journal_title：Neural regeneration research

authors： So KF,Leung MC,Cui Q

更新日期：2014-11-01 00:00:00

abstract：:Neuroprotection by ischemic preconditioning has been confirmed by many studies, but the precise mechanism remains unclear. In the present study, we performed cerebral ischemic preconditioning in rats by simulating a transient ischemic attack twice (each a 20-minute occlusion of the middle cerebral artery) before induc...

journal_title：Neural regeneration research

authors： Liu Y,Zhu S,Wang Y,Hu J,Xu L,Ding L,Liu G

更新日期：2014-06-01 00:00:00

abstract：:Anti-inflammatory and anti-oxidant agents can alleviate ischemic cerebral injury. The immunomodulary drug Setarud, which is composed of herbal extracts including Rosa canina, Urtica dioica and Tanacetum vulgare, supplemented with selenium exhibits anti-inflammatory and anti-oxidant properties. Therefore, we hypothesiz...

journal_title：Neural regeneration research

authors： Vafaee F,Zangiabadi N,Pour FM,Dehghanian F,Asadi-Shekaari M,Afshar HK

更新日期：2012-09-25 00:00:00

abstract：:Intrinsically disordered proteins, such as tau or α-synuclein, have long been associated with a dysfunctional role in neurodegenerative diseases. In Alzheimer's and Parkinson's' diseases, these proteins, sharing a common chemical-physical pattern with alternating hydrophobic and hydrophilic domains rich in prolines, a...

journal_title：Neural regeneration research

authors： Caminati G,Procacci P

更新日期：2020-12-01 00:00:00

abstract：:Our previous studies have histomorphologically confirmed that nanofibrous poly(3-hydroxybutyrate-co-3-hydroxyvalerate) conduit can be used to repair 30-mm-long sciatic nerve defects. However, the repair effects on rat behaviors remain poorly understood. In this study, we used nanofibrous poly(3-hydroxybutyrate-co-3-hy...

journal_title：Neural regeneration research

authors： Biazar E,Keshel SH,Pouya M

更新日期：2013-09-25 00:00:00

abstract：:Recent studies have shown that induced expression of endogenous antioxidative enzymes thr-ough activation of the antioxidant response element/nuclear factor erythroid 2-related factor 2 (Nrf2) pathway may be a neuroprotective strategy. In this study, rat cerebral cortical neurons cultured in vitro were pretreated with...

journal_title：Neural regeneration research

authors： Wu JX,Zhang LY,Chen YL,Yu SS,Zhao Y,Zhao J

更新日期：2015-03-01 00:00:00

abstract：:Multiple sclerosis is a chronic, inflammatory and degenerative disease of the central nervous system of unknown aetiology although well-defined evidence supports an autoimmune pathogenesis. So far, the exact mechanisms leading to autoimmune diseases are still only partially understood. We know that genetic, epigenetic...

journal_title：Neural regeneration research

authors： Nociti V,Santoro M

更新日期：2021-09-01 00:00:00

abstract：:We report a patient with severe ataxia due to Dandy-Walker malformation, who showed functional recovery over 10 months corresponding to a change in a cerebellar peduncle lesion. A 20-month-old female patient who was diagnosed with Dandy-Walker syndrome and six age- and sex-matched healthy control subjects were enrolle...

journal_title：Neural regeneration research

authors： Lee AY,Jang SH,Yeo SS,Lee E,Cho YW,Son SM

更新日期：2013-02-15 00:00:00

abstract：:Active Achilles tendon kinesitherapy facilitates the functional recovery of a ruptured Achilles tendon. However, protein expression during the healing process remains a controversial issue. New Zealand rabbits, aged 14 weeks, underwent tenotomy followed immediately by Achilles tendon microsurgery to repair the Achille...

journal_title：Neural regeneration research

authors： Jielile J,Aibai M,Sabirhazi G,Shawutali N,Tangkejie W,Badelhan A,Nuerduola Y,Satewalede T,Buranbai D,Hunapia B,Jialihasi A,Bai J,Kizaibek M

更新日期：2012-12-15 00:00:00

abstract：:Excessive radiation exposure may lead to edema of the spinal cord and deterioration of the nervous system. Magnetic resonance imaging can be used to judge and assess the extent of edema and to evaluate pathological changes and thus may be used for the evaluation of spinal cord injuries caused by radiation therapy. Rad...

journal_title：Neural regeneration research

authors： Cao X,Fang L,Cui CY,Gao S,Wang TW

更新日期：2018-03-01 00:00:00

abstract：:Stem cell transplantation has brought new hope for the treatment of neurological diseases. The key to stem cell therapy lies in inducing the specific differentiation of stem cells into nerve cells. Because the differentiation of stem cells in vitro and in vivo is affected by multiple factors, the final differentiation...

journal_title：Neural regeneration research

authors： Ren C,Ji YQ,Liu H,Wang Z,Wang JH,Zhang CY,Guan LN,Yin PY

更新日期：2019-07-01 00:00:00

abstract：:Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis are a heterogeneous group of debilitating disorders with multifactorial etiologies and pathogeneses that manifest distinct molecular mechanisms and clinical manifestations with abnormal ...

journal_title：Neural regeneration research

authors： Onyango IG,Bennett JP,Stokin GB

更新日期：2021-08-01 00:00:00

abstract：:Yizhijiannao granules have been shown to improve cognitive function in Alzheimer's disease patients. The present study sought to explore the mechanisms involved in the cognitive enhancing effects of Yizhijiannao granule. Senescence-accelerated mouse prone 8 mice with learning and memory disorders were intragastrically...

journal_title：Neural regeneration research

authors： Zhu H,Luo L,Hu S,Dong K,Li G,Zhang T

更新日期：2014-07-01 00:00:00

abstract：:Parkinson's disease is characterized by the loss of dopaminergic neurons in the substantia nigra. As a result, intensive efforts have focused upon mechanisms that facilitate the death of mature dopaminergic neurons. Unfortunately, these efforts have been unsuccessful in providing an effective treatment to address neur...

journal_title：Neural regeneration research

authors： Morrison BE

更新日期：2016-06-01 00:00:00

abstract：:Ca2+ channel blockers have been shown to protect neurons from ischemia, and aerobic exercise has significant protective effects on a variety of chronic diseases. The present study injected huwentoxin-I (HWTX-I), a spider peptide toxin that blocks Ca2+ channels, into the caudal vein of a chronic cerebral ischemia mouse...

journal_title：Neural regeneration research

authors： Mao HF,Xie J,Chen JQ,Tang CF,Chen W,Zhou BC,Chen R,Qu HL,Wu CZ

更新日期：2017-04-01 00:00:00

abstract：:Paired associative stimulation has been used in stroke patients as an innovative recovery treatment. However, the mechanisms underlying the therapeutic effectiveness of paired associative stimulation on neurological function remain unclear. In this study, rats were randomly divided into middle cerebral occlusion model...

journal_title：Neural regeneration research

authors： Gao BY,Sun CC,Xia GH,Zhou ST,Zhang Y,Mao YR,Liu PL,Zheng Y,Zhao D,Li XT,Xu J,Xu DS,Bai YL

更新日期：2020-11-01 00:00:00

abstract：:Recent studies have shown that tea polyphenols can cross the blood-brain barrier, inhibit apoptosis and play a neuroprotective role against cerebral ischemia. Furthermore, tea polyphenols can decrease DNA damage caused by free radicals. We hypothesized that tea polyphenols repair DNA damage and inhibit neuronal apopto...

journal_title：Neural regeneration research

authors： Wang Z,Xue R,Lei X,Lv J,Wu G,Li W,Xue L,Lei X,Zhao H,Gao H,Wei X

更新日期：2012-10-25 00:00:00

abstract：:Electroacupuncture improves depressive behavior faster and with fewer adverse effects than antidepressant medication. However, the antidepressant mechanism of electroacupuncture remains poorly understood. Here, we established a rat model of chronic unpredicted mild stress, and then treated these rats with electroacupu...

journal_title：Neural regeneration research

authors： Duan DM,Tu Y,Liu P,Jiao S

更新日期：2016-10-01 00:00:00

abstract：:This study investigated the effects of small interfering RNA (siRNA)-mediated silencing of chemokine receptor 4 (CXCR4) on the invasion capacity of human neuroblastoma cell line SH-SY5Y in vitro. Three siRNAs targeting CXCR4 were chemically synthesized and individually transfected into SH-SY5Y cells. Expression of CXC...

journal_title：Neural regeneration research

authors： Chen X,Zhu Y,Han L,Lu H,Hao X,Dong Q

更新日期：2014-05-15 00:00:00

abstract：:The present study involved a questionnaire survey of 156 mothers that gave birth to children with neural tube defects or had a history of pregnancy resulting in children with neural tube defects (case group) and 156 control mothers with concurrent healthy children (control group) as well as detection of mitochondrial ...

journal_title：Neural regeneration research

authors： Liu Z,Xie J,Luo T,Zhang T,Zhao X,Zhao H,Li P

更新日期：2012-02-25 00:00:00

abstract：:[This corrects the article on p. 770 in vol. 12, PMID: 28616034.]. ...

journal_title：Neural regeneration research

authors： Lu J,Guo Y,Guo CQ,Shi XM,Du NY,Zhao RL,Du WP,Liang JR,Zhu SP,Chen H

更新日期：2017-06-01 00:00:00

abstract：:After binding to the estrogen receptor, estrogen can alleviate the toxic effects of beta-amyloid protein, and thereby exert a therapeutic effect on Alzheimer's disease patients. Estrogen can increase the incidence of breast carcinoma and endometrial cancer in post-menopausal women, so it is not suitable for clinical t...

journal_title：Neural regeneration research

authors： Wang H,Si L,Li X,Deng W,Yang H,Yang Y,Fu Y

更新日期：2012-05-15 00:00:00

abstract：:Cavernous nerve injury is the main cause of erectile dysfunction following radical prostatectomy. The recovery of erectile function following radical prostatectomy remains challenging. Our previous studies found that injecting adipose-derived stem cells (ADSCs) into the cavernosa could repair the damaged cavernous ner...

journal_title：Neural regeneration research

authors： Yang M,Sun JY,Ying CC,Wang Y,Guo YL

更新日期：2020-01-01 00:00:00

abstract：:Alzheimer's disease is the leading cause of dementia. Its increased prevalence in developed countries, due to the sharp rise in ageing populations, presents one of the costliest challenges to modern medicine. In order to find disease-modifying therapies to confront this challenge, a more complete understanding of the ...

journal_title：Neural regeneration research

authors： Gray SC,Kinghorn KJ,Woodling NS

更新日期：2020-07-01 00:00:00

abstract：:The structural plasticity of synaptic terminals contributes to normal nervous system function but also to neural degeneration, in the form of terminal retraction, and regeneration, due to process growth. Synaptic morphological change is mediated through the actin cytoskeleton, which is enriched in axonal and dendritic...

journal_title：Neural regeneration research

authors： Wang W,Townes-Anderson E

更新日期：2016-07-01 00:00:00

abstract：:The γ-aminobutyric acid neurotransmitter in the spinal cord dorsal horn plays an important role in pain modulation through primary afferent-mediated presynaptic inhibition. The weakening of γ-aminobutyric acid-mediated presynaptic inhibition may be an important cause of neuropathic pain. γ-aminobutyric acid-mediated p...

journal_title：Neural regeneration research

authors： Lian Y,Wang Y,Ma K,Zhao L,Zhang Z,Shang Y,Si J,Li L

更新日期：2012-11-15 00:00:00

abstract：:Decreased expression of brain-derived neurotrophic factor (BDNF) plays an important role in the pathogenesis of Alzheimer's disease, and a typical pathological change in Alzheimer's disease is neurofibrillary tangles caused by hyperphosphorylation of tau. An in vivo model of Alzheimer's disease was developed by inject...

journal_title：Neural regeneration research

authors： Xu AH,Yang Y,Sun YX,Zhang CD

更新日期：2018-12-01 00:00:00

abstract：:The study illustrates that graphene oxide nanosheets can endow materials with continuous electrical conductivity for up to 4 weeks. Conductive nerve scaffolds can bridge a sciatic nerve injury and guide the growth of neurons; however, whether the scaffolds can be used for the repair of spinal cord nerve injuries remai...

journal_title：Neural regeneration research

authors： Yang B,Wang PB,Mu N,Ma K,Wang S,Yang CY,Huang ZB,Lai Y,Feng H,Yin GF,Chen TN,Hu CS

更新日期：2021-09-01 00:00:00