Spinal cord contusion.

abstract：:Neurotropic herpesviruses have been associated with the onset and progression of Alzheimer's disease, a common form of dementia that afflicts a large percentage of elderly individuals. Interestingly, among the neurotropic herpesviruses, herpes simplex virus-1, human herpesvirus-6A, and human herpesvirus-6B have been r...

journal_title：Neural regeneration research

authors： Romeo MA,Faggioni A,Cirone M

更新日期：2019-09-01 00:00:00

abstract：:The optic nerve is a viscoelastic solid-like biomaterial. Its normal stress relaxation and creep properties enable the nerve to resist constant strain and protect it from injury. We hypothesized that stress relaxation and creep properties of the optic nerve change after injury. More-over, human brain-derived neurotrop...

journal_title：Neural regeneration research

authors： Lv XM,Liu Y,Wu F,Yuan Y,Luo M

更新日期：2016-04-01 00:00:00

abstract：:Emodin, an extract of dried rhizomes and the root of the Rhizoma Polygoni Cuspidati, can protect neurons from hypoxic-ischemic brain damage. This study aimed to verify the underlying mechanism. After PC12 cells had differentiated into neuron-like cells under the induction of mouse nerve growth factor, cells were subje...

journal_title：Neural regeneration research

authors： Guo H,Shen X,Xu Y,Yuan J,Zhao D,Hu W

更新日期：2013-05-25 00:00:00

abstract：:To date, it remains poorly understood whether astrocytes can be easily reprogrammed into neurons. Mash1 and Brn2 have been previously shown to cooperate to reprogram fibroblasts into neurons. In this study, we examined astrocytes from 2-month-old Sprague-Dawley rats, and found that Brn2 was expressed, but Mash1 was no...

journal_title：Neural regeneration research

authors： Ding D,Xu L,Xu H,Li X,Liang Q,Zhao Y,Wang Y

更新日期：2014-01-01 00:00:00

abstract：:In this study, we hypothesized that an increase in integrin αvβ3 and its co-activator vascular endothelial growth factor play important neuroprotective roles in ischemic injury. We performed ischemic preconditioning with bilateral common carotid artery occlusion for 5 minutes in C57BL/6J mice. This was followed by isc...

journal_title：Neural regeneration research

authors： Ma XM,Liu M,Liu YY,Ma LL,Jiang Y,Chen XH

更新日期：2016-05-01 00:00:00

abstract：:Proximal or middle lesions of the ulnar or median nerves are responsible for extensive loss of hand motor function. This occurs even when the most meticulous microsurgical techniques or nerve grafts are used. Previous studies had proposed that nerve transfer was more effective than nerve grafting for nerve repair. Our...

journal_title：Neural regeneration research

authors： Wang PJ,Zhang Y,Zhao JJ,Zhou JP,Zuo ZC,Wu BB

更新日期：2017-01-01 00:00:00

abstract：:The sciatic functional index (SFI) is a popular parameter for peripheral nerve evaluation that relies on footprints obtained with ink and paper. Drawbacks include smearing artefacts and a lack of dynamic information during measurement. Modern applications use digitized systems that can deliver results with less analyt...

journal_title：Neural regeneration research

authors： Fricker L,Penna V,Lampert F,Stark GB,Witzel C,Koulaxouzidis G

更新日期：2016-05-01 00:00:00

abstract：:After binding to the estrogen receptor, estrogen can alleviate the toxic effects of beta-amyloid protein, and thereby exert a therapeutic effect on Alzheimer's disease patients. Estrogen can increase the incidence of breast carcinoma and endometrial cancer in post-menopausal women, so it is not suitable for clinical t...

journal_title：Neural regeneration research

authors： Wang H,Si L,Li X,Deng W,Yang H,Yang Y,Fu Y

更新日期：2012-05-15 00:00:00

abstract：:Suture and autologous nerve transplantation are the primary therapeutic measures for completely severed nerves. However, imbalances in the microenvironment and adhesion of surrounding tissues can affect the quality of nerve regeneration and repair. Previous studies have shown that human amniotic membrane can promote t...

journal_title：Neural regeneration research

authors： Zhang ZY,Yang J,Fan ZH,Wang DL,Wang YY,Zhang T,Yu LM,Yu CY

更新日期：2019-12-01 00:00:00

abstract：:Molecular mechanisms of the Krüppel-like family of transcription factors (KLFs) have been studied more in proliferating cells than in post-mitotic cells such as neurons. We recently found that KLFs regulate intrinsic axon growth ability in central nervous system (CNS) neurons including retinal ganglion cells, and hipp...

journal_title：Neural regeneration research

authors： Apara A,Goldberg JL

更新日期：2014-08-01 00:00:00

abstract：:Yizhijiannao granules have been shown to improve cognitive function in Alzheimer's disease patients. The present study sought to explore the mechanisms involved in the cognitive enhancing effects of Yizhijiannao granule. Senescence-accelerated mouse prone 8 mice with learning and memory disorders were intragastrically...

journal_title：Neural regeneration research

authors： Zhu H,Luo L,Hu S,Dong K,Li G,Zhang T

更新日期：2014-07-01 00:00:00

abstract：:Parkinson's disease is characterized by the loss of dopaminergic neurons in the substantia nigra. As a result, intensive efforts have focused upon mechanisms that facilitate the death of mature dopaminergic neurons. Unfortunately, these efforts have been unsuccessful in providing an effective treatment to address neur...

journal_title：Neural regeneration research

authors： Morrison BE

更新日期：2016-06-01 00:00:00

abstract：:Sterile inflammatory processes are essential for the maintenance of central nervous system homeostasis, but they also contribute to various neurological disorders, including neurotrauma, stroke, and demyelinating or neurodegenerative diseases. Immune mechanisms in the central nervous system and periphery are regulated...

journal_title：Neural regeneration research

authors： Klegeris A

更新日期：2021-03-01 00:00:00

abstract：:Neuropathic pain after spinal cord injury (SCI) is a complex condition that responds poorly to usual treatments. Cell transplantation represents a promising therapy; nevertheless, the ideal cell type in terms of neurogenic potential and effectiveness against pain remains largely controversial. Here, we evaluated the a...

journal_title：Neural regeneration research

authors： Batista CM,Mariano ED,Dale CS,Cristante AF,Britto LR,Otoch JP,Teixeira MJ,Morgalla M,Lepski G

更新日期：2019-11-01 00:00:00

abstract：:The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury. However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell death. By comparing the survival rate and morphology of primary neurons and SH-SY5Y cells exposed to erastin, it was found that these c...

journal_title：Neural regeneration research

authors： Zhang Y,Fan BY,Pang YL,Shen WY,Wang X,Zhao CX,Li WX,Liu C,Kong XH,Ning GZ,Feng SQ,Yao X

更新日期：2020-08-01 00:00:00

abstract：:Chalcone is a plant metabolite widely found in fruits, vegetables, spices and tea, and has anti-tumor, anti-inflammation, immunomodulation, antibacterial and anti-oxidation activities, as well as many other pharmacological and biological effects. Our team has shown that its analogs have antioxidant activity, and oxida...

journal_title：Neural regeneration research

authors： Wang L,Chen HC,Yang X,Tao JJ,Liang G,Wu JZ,Wu WC,Wang Y,Song ZM,Zhang X

更新日期：2018-09-01 00:00:00

abstract：:Schwann cells and neurotrophin-3 play an important role in neural regeneration, but the secretion of neurotrophin-3 from Schwann cells is limited, and exogenous neurotrophin-3 is inactived easily in vivo. In this study, we have transfected neurotrophin-3 into Schwann cells cultured in vitro using nanoparticle liposome...

journal_title：Neural regeneration research

authors： Zong H,Zhao H,Zhao Y,Jia J,Yang L,Ma C,Zhang Y,Dong Y

更新日期：2013-05-15 00:00:00

abstract：:Both matrix biochemistry and neurotrophic factors are known to modulate neurite outgrowth and pathfinding; however, the interplay between these two factors is less studied. While previous work has shown that the biochemical identity of the matrix can alter the outgrowth of neurites in response to neurotrophins, the im...

journal_title：Neural regeneration research

authors： Madl CM,Heilshorn SC

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To identify global research trends in three therapies for children with cerebral palsy. DATA RETRIEVAL:We performed a bibliometric analysis of studies on therapies for children with cerebral palsy from 2002 to 2011 retrieved from Web of Science. SELECTION CRITERIA: INCLUSION CRITERIA:(a) peer-reviewed publ...

journal_title：Neural regeneration research

authors： Mu Y,Li N,Guan L,Wang C,Shang S,Wang Y

更新日期：2012-11-25 00:00:00

abstract：:This study investigated the effect of transcranial direct current stimulation (tDCS) polarity depending on lateralized function of task property in normal individuals performing visuomotor and simple repetitive tasks. Thirty healthy participants with no neurological disorders were recruited to participate in this stud...

journal_title：Neural regeneration research

authors： Kwon YH,Kang KW,Lee NK,Son SM

更新日期：2016-01-01 00:00:00

abstract：:In this study, we tried to verify the neuroprotective effect of Chrysanthemum indicum Linne (CIL) extract, which has been used as a botanical drug in East Asia, against ischemic damage and to explore the underlying mechanism involving the anti-inflammatory approach. A gerbil was given CIL extract for 7 consecutive day...

journal_title：Neural regeneration research

authors： Yoo KY,Kim IH,Cho JH,Ahn JH,Park JH,Lee JC,Tae HJ,Kim DW,Kim JD,Hong S,Won MH,Kang IJ

更新日期：2016-02-01 00:00:00

abstract：:Apolipoprotein E plays a crucial role in inhibiting chronic neurodegenerative processes. However, its impact on neurological function following diffuse brain injury is still unclear. This study was designed to evaluate the therapeutic effects and mechanisms of action of apolipoprotein E mimetic peptide on diffuse brai...

journal_title：Neural regeneration research

authors： Zhao Y,Li J,Tang Q,Gao J,Chen C,Jing L,Zhang P,Li S

更新日期：2014-03-01 00:00:00

abstract：:At 8 weeks after intragastric administration of icariin to senescence-accelerated mice (P8 strain), Morris water maze results showed that escape latency was shortened, and the number of platform crossings was increased. Immunohistochemical staining and western blot assay detected significantly increased levels of cycl...

journal_title：Neural regeneration research

authors： Zhang Z,Zhang T,Dong K

更新日期：2012-04-25 00:00:00

abstract：:Although Parkinson's disease is the most common neurodegenerative movement disorder, the mechanisms of pathogenesis remain poorly understood. Recent findings have shown that deregulation of the autophagy-lysosome pathway is involved in the pathogenesis of Parkinson's disease. This review summarizes the most recent fin...

journal_title：Neural regeneration research

authors： Zhang L,Dong Y,Xu X,Xu Z

更新日期：2012-01-15 00:00:00

abstract：:Visual cortical prostheses have the potential to restore partial vision. Still limited by the low-resolution visual percepts provided by visual cortical prostheses, implant wearers can currently only "see" pixelized images, and how to obtain the specific brain responses to different pixelized images in the primary vis...

journal_title：Neural regeneration research

authors： Guo BB,Zheng XL,Lu ZG,Wang X,Yin ZQ,Hou WS,Meng M

更新日期：2015-10-01 00:00:00

abstract：:Alzheimer's disease is the leading cause of dementia. Its increased prevalence in developed countries, due to the sharp rise in ageing populations, presents one of the costliest challenges to modern medicine. In order to find disease-modifying therapies to confront this challenge, a more complete understanding of the ...

journal_title：Neural regeneration research

authors： Gray SC,Kinghorn KJ,Woodling NS

更新日期：2020-07-01 00:00:00

abstract：Objective:To critically assess the neurological recovery and antioxidant effects of resveratrol in rat models of spinal cord injury. Data sources:Using "spinal cord injury", "resveratrol" and "animal experiment" as the main search terms, all studies on the treatment of spinal cord injury in rats by resveratrol were se...

journal_title：Neural regeneration research

authors： Xu BP,Yao M,Li ZJ,Tian ZR,Ye J,Wang YJ,Cui XJ

更新日期：2020-03-01 00:00:00

abstract：:Paired associative stimulation has been used in stroke patients as an innovative recovery treatment. However, the mechanisms underlying the therapeutic effectiveness of paired associative stimulation on neurological function remain unclear. In this study, rats were randomly divided into middle cerebral occlusion model...

journal_title：Neural regeneration research

authors： Gao BY,Sun CC,Xia GH,Zhou ST,Zhang Y,Mao YR,Liu PL,Zheng Y,Zhao D,Li XT,Xu J,Xu DS,Bai YL

更新日期：2020-11-01 00:00:00

abstract：:Alzheimer's disease is a progressive neurodegenerative disorder, characterized by deposition of amyloid beta, neurofibrillary tangles, astrogliosis and microgliosis, leading to neuronal dysfunction and loss in the brain. Current treatments for Alzheimer's disease primarily focus on enhancement of cholinergic transmiss...

journal_title：Neural regeneration research

authors： Venigalla M,Gyengesi E,Münch G

更新日期：2015-08-01 00:00:00

abstract：:The study aims to confirm the neuroregenerative effects of bacterial melanin (BM) on central nervous system injury using a special staining method based on the detection of Ca(2+)-dependent acid phosphatase activity. Twenty-four rats were randomly assigned to undergo either unilateral destruction of sensorimotor corte...

journal_title：Neural regeneration research

authors： Petrosyan TR,Ter-Markosyan AS,Hovsepyan AS

更新日期：2016-07-01 00:00:00