Ultraviolet-radiation and health: optimal time for sun exposure.

Abstract:

:Positive as well as negative health effects of exposure of human skin to UV radiation depend on spectra and fluence rates, both of which being dependent on latitude, time of the day and several other factors. The major positive effects are related to vitamin D photosynthesis and the major negative effect is skin cancer development. The action spectra for these effects are different. This lead us to conclude that for optimal vitamin D synthesis at minimal risk of cutaneous malignant melanoma (CMM), the best time for sun exposure is between 10 a.m. and 1 p.m. Thus, the common health recommendation (that sun exposure should be avoided between the hours of 10 a.m. and 4 p.m. and postponed to the afternoon) may be wrong.

journal_name

Adv Exp Med Biol

authors

Moan J,Grigalavicius M,Dahlback A,Baturaite Z,Juzeniene A

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

423-8

eissn

0065-2598

issn

2214-8019

journal_volume

810

pub_type

杂志文章
  • Physical interaction between lung epithelial cells and T lymphocytes.

    abstract::The present results support a role for epithelial cells in the activation of T cells in an apparent antigen-independent manner. The transient expression of CD25 indicates a short acting T cells activation. Possibly, this event primes T cells to respond swiftly upon antigen-specific stimulation or to synthesize mediato...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-1941-6_54

    authors: Lutter R,Bruinier B,Hol BE,Krouwels FH,Out TA,Jansen HM

    更新日期:1995-01-01 00:00:00

  • Drug Screening Platforms and RPPA.

    abstract::Since its inception as a scalable and cost-effective method for precise quantification of the abundance of multiple protein analytes and post-translational epitopes across large sample sets, reverse phase protein array (RPPA) has been utilized as a drug discovery tool. Key RPPA drug discovery applications include prim...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-981-32-9755-5_11

    authors: Dawson JC,Warchal SJ,Carragher NO

    更新日期:2019-01-01 00:00:00

  • Semantic Processing.

    abstract::In the previous chapter we were able to automatically process text by recognizing a limited set of entities. This chapter will introduce the world of semantics, and present step-by-step examples to retrieve and enhance text and data processing by using semantics. The goal is to equip the reader with the basic set of s...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-030-13845-5_5

    authors: Couto FM

    更新日期:2019-01-01 00:00:00

  • Emerging roles for A20 in islet biology and pathology.

    abstract::A20 is most characteristically described in terms relating to inflammation and inflammatory pathologies. The emerging understanding of inflammation in the etiology of diabetes mellitus lays the framework for considering a central role for A20 in this disease process. Diabetes mellitus is considered a major health issu...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4939-0398-6_9

    authors: Zammit NW,Grey ST

    更新日期:2014-01-01 00:00:00

  • Carbon-13 magnetic resonance probe of coenzyme and inhibitor binding in liver alcohol dehydrogenase.

    abstract::Horse liver alcohol dehydrogenase was carboxymethylated at the active site Cys-46 using 90% [1-13C]bromoacetate. The enriched carboxylate resonance was studied in the absence and presence of coenzymes and inhibitors. Previous ambiguities regarding the resonance in the NAD+ complex have now been resolved. However, it i...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4757-1419-7_9

    authors: Jones DT,Khalifah RG

    更新日期:1980-01-01 00:00:00

  • Innate immunity as orchestrator of bone marrow homing for hematopoietic stem/progenitor cells.

    abstract::The first step that precedes hematopoietic transplantation is elimination of pathological hematopoiesis by administration of myeloablative doses of radiochemotherapy. This eliminates hematolymphopoietic cells and at the same time damages hematopoietic microenvironment in bone marrow (BM). The damage of BM tissue leads...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4614-4118-2_15

    authors: Ratajczak MZ,Kim C,Ratajczak J,Janowska-Wieczorek A

    更新日期:2013-01-01 00:00:00

  • Mechanisms of active intestinal inflammation and potential down-regulation via lipoxins.

    abstract::Chronic inflammatory diseases of the intestine (i.e. Crohn's and chronic ulcerative colitis- collectively known as inflammatory bowel disease [IBD]) are a very significant public health problem in the United States and other industrialized nations. Thus, effort has been made toward understanding the biological mechani...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-0193-0_35

    authors: Gewirtz AT,Neish AS,Madara JL

    更新日期:2002-01-01 00:00:00

  • Analysis of SDHD and MMP12 in an affected solar keratosis and control cohort.

    abstract::The incidence of Squamous Cell Carcinoma (SCG) is growing in certain populations to the extent that it is now the most common skin lesion in young men and women in high ultraviolet exposure regions such as Queensland. In terms of incidence up to 40% of the Australian population over 40 years of age is thought to posse...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-0-387-71764-7_11

    authors: Lintell NA,Maguire DJ,Griffiths LR,McCabe M

    更新日期:2007-01-01 00:00:00

  • Clinical relevance of terminal transferase and adenosine deaminase in leukemia.

    abstract::Terminal Transferase (TdT), Adenosine Deaminase (ADA), immunological membrane markers, cytochemical reactivity and cytogenetics were analyzed in 226 patients with ALL, AUL and AML, in 70 patients with CML and in 3 cases of Ph' positive acute leukemia presenting as ALL. TdT was tested in peripheral blood and bone marro...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-8929-3_24

    authors: Brusamolino E,Bertazzoni U,Isernia P,Ginelli E,Scovassi AI,Zurlo MG,Plevani P,Sacchi N,Bernasconi C

    更新日期:1982-01-01 00:00:00

  • Circannual rhythms in progesterone receptor levels and functions.

    abstract::Studies in this laboratory on the nuclear binding sites (acceptors) for progesterone receptor in the developed chick oviduct have resulted in the detection of seasonal variations in the levels and functions of the receptor. Cytosol preparations obtained from the chick oviducts during the winter/spring period between J...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4757-6589-2_13

    authors: Spelsberg TC,Boyd PA,Halberg F

    更新日期:1979-01-01 00:00:00

  • Flow cytometry in the diagnosis of influenza.

    abstract::Flow cytometry is used in the analysis of the multi-parameter optical properties of individual particles such as eukaryotic cells, prokaryotic cells, and viruses in the flow system. Virions, or complexes consisting of virus particles attached to the specific antibody in suspension are individually arranged in a linear...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-94-007-6627-3_10

    authors: Wozniak-Kosek A,Brydak LB

    更新日期:2013-01-01 00:00:00

  • Interventions to Prevent Sperm DNA Damage Effects on Reproduction.

    abstract::Excessive oxidation and antioxidant imbalance resulting from several conditions may cause sperm DNA damage, which, in turn, affect male fertility, both natural and assisted. Sperm DNA damage transferred to the embryo might also affect the health of offspring. Several conditions associated with excessive oxidative stre...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-030-21664-1_8

    authors: Esteves SC

    更新日期:2019-01-01 00:00:00

  • Skeletal muscle alpha-actin diseases.

    abstract::Skeletal muscle alpha-actin is the principal protein component of the adult skeletal muscle thin filament. The interaction between skeletal muscle alpha-actin and the various myosin heavy chain proteins in the different muscle fibre types generates the force of muscle contraction. Skeletal muscle alpha-alpha actin is ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-0-387-84847-1_2

    authors: North KN,Laing NG

    更新日期:2008-01-01 00:00:00

  • Rescue of IBV D-RNA by heterologous helper virus strains.

    abstract::Coronavirus defective RNA (D-RNA) vectors could be developed to deliver selected genes for the production of recombinant coronavirus vaccines. An IBV D-RNA, CD-61, derived from a naturally occurring IBV Beaudette D-RNA, CD-91, is being developed as a D-RNA vector for IBV. In order to use CD-61 as a vector it will requ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-5331-1_33

    authors: Stirrups K,Shaw K,Evans S,Dalton K,Cavanagh D,Britton P

    更新日期:1998-01-01 00:00:00

  • Communicating the Issue of Underwater Noise Pollution: The Deaf as a Fish Project.

    abstract::Aquatic noise pollution is largely ignored by the lay public. How experts communicate this issue is critical to move public opinion. In 2010, the Cassa di Risparmio di Gorizia (CaRiGO) bank sponsored the Deaf as a Fish project that included local underwater noise monitoring, a boat census, a pamphlet for nonexperts, a...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4939-2981-8_123

    authors: Sebastianutto L,Stocker M,Picciulin M

    更新日期:2016-01-01 00:00:00

  • Suitability of tryptophan radiation products as markers for the detection of gamma-irradiated protein rich food.

    abstract::During gamma-irradiation (5 kGy) of aqueous tryptophan (Trp) solutions small amounts of 5-, 6-, and 7-hydroxytryptophan (OH-Trp) (0.04-0.08 Mol-%) are formed. Protein rich food like shrimps contain reasonable amounts of non-protein bound Trp (100 mg/kg). In order to detect the treatment of shrimps with gamma-irradiati...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-0135-0_80

    authors: Kleeberg KK,Müller A,Simat TJ,Steinhart H

    更新日期:2003-01-01 00:00:00

  • The roles of two-component systems in virulence of pathogenic Escherichia coli and Shigella spp.

    abstract::Two-component systems (TCSs) are well conserved among E. coli strains, including pathogenic E. coli and also closely related Shigella spp. Although 25% of the genome of pathogenic E. coli is strain-specific, only small number of strain-specific TCSs is found. Regulation of virulence genes in response to environmental ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-0-387-78885-2_13

    authors: Tobe T

    更新日期:2008-01-01 00:00:00

  • Are there really "epileptogenic" mechanisms or only corruptions of "normal" plasticity?

    abstract::Plasticity in the nervous system, whether for establishing connections and networks during development, repairing networks after injury, or modifying connections based on experience, relies primarily on highly coordinated patterns of neural activity. Rhythmic, synchronized bursting of neuronal ensembles is a fundament...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-94-017-8914-1_8

    authors: Avanzini G,Forcelli PA,Gale K

    更新日期:2014-01-01 00:00:00

  • Differential Contribution of Calcium-Activated Proteases and ER-Stress in Three Mouse Models of Retinitis Pigmentosa Expressing P23H Mutant RHO.

    abstract::Autosomal dominant retinitis pigmentosa (adRP) is mainly caused by mutations responsible for rhodopsin (RHO) misfolding. Although it was previously proved that unfolded RHO is retained into the endoplasmatic reticulum (ER) eliciting ER-stress, consequent mechanisms underlying photoreceptor degeneration need to be furt...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-030-27378-1_51

    authors: Comitato A,Schiroli D,La Marca C,Marigo V

    更新日期:2019-01-01 00:00:00

  • Definition, Derivation, and Diagnosis of Barrett's Esophagus: Pathological Perspectives.

    abstract::More than 60 years have elapsed since Barrett described the condition that continues to bear his name. Despite much research, clinical and basic, the defining features and the diagnosis of columnar-lined esophagus (CLO) are still embroiled with controversy and uncertainty. For pathologists, these controversies are not...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-319-41388-4_7

    authors: Lowes H,Somarathna T,Shepherd NA

    更新日期:2016-01-01 00:00:00

  • Stretch of contracting muscle fibres: evidence for regularly spaced active sites along the filaments and enhanced mechanical performance.

    abstract::Single frog skeletal muscle fibres were stretched during fused tetanic contractions. The force increase during stretch exhibited a breakpoint at a mean critical length change of 16.6 nm per half sarcomere that was independent of stretch velocity and sarcomere length. The early decaying extra force after stretch (compo...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-4703-3_71

    authors: Edman KA,Elzinga G,Noble MI

    更新日期:1984-01-01 00:00:00

  • Oxygen sensor design: analysis and correction of problems associated with zero current, stability and structure.

    abstract::Membrane-covered polarographic sensors were designed by Leland Clark several decades ago. The membrane covering was a brilliant innovation because it provided an isolation of electrochemical elements from the external environment. These sensors have found a wide range of applications in many aspects of medicine, resea...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-0205-0_25

    authors: Koch CJ

    更新日期:2003-01-01 00:00:00

  • Roles of Slit Ligands and Their Roundabout (Robo) Family of Receptors in Bone Remodeling.

    abstract::Slit guidance ligands (Slits) and their roundabout (Robo) family of receptors are well-known axon guidance molecules that were originally identified in Drosophila mutants with commissural axon pathfinding defects. However, Slit-Robo signaling has been shown to be involved in not only neurogenesis, but also the develop...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/5584_2020_586

    authors: Niimi T

    更新日期:2020-09-29 00:00:00

  • Influence of glycopeptide antibiotics on purine metabolism of endothelial cells.

    abstract::We provide evidence that the commercially available preparations of glycopeptides for intravenous application are well tolerated by endothelial cells when applied in concentrations less than 5 mg/ml. Since the antibiotics tested are administered at maximal concentrations of 10 mg/ml, the dose range used in our in vitr...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-5381-6_160

    authors: Robibaro B,Vorbach H,Weigel G,Weihs A,Hlousek M,Presterl E,Georgopoulos A,Griesmacher A,Graninger W

    更新日期:1998-01-01 00:00:00

  • Effects of cytokines on glucocorticoid receptor expression and function. Glucocorticoid resistance and relevance to depression.

    abstract::Our data indicate that the proinflammatory cytokine, IL-1alpha inhibits GR translocation and hormone-induced GR-mediated gene transcription, and, in conjunction with previous in vivo and in vitro studies, can be interpreted to suggest that cytokines have the capacity to contribute to glucocorticoid resistance and thus...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-0-585-37970-8_7

    authors: Miller AH,Pariante CM,Pearce BD

    更新日期:1999-01-01 00:00:00

  • Microglia in the aging retina.

    abstract::In the healthy retina, microglial cells represent a self-renewing population of innate immune cells, which constantly survey their microenvironment. Equipped with receptors, a microglial cell detects subtle cellular damage and rapidly responds with activation, migration, and increased phagocytic activity. While the in...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4614-3209-8_27

    authors: Karlstetter M,Langmann T

    更新日期:2014-01-01 00:00:00

  • In vivo metabolic evaluation of breast tumor mouse xenografts for predicting aggressiveness using the hyperpolarized (13)C-NMR technique.

    abstract::In vivo imaging/spectroscopic biomarkers for solid tumor aggressiveness are needed in the clinic to facilitate cancer diagnosis and treatment strategies. In mouse models of human melanoma and breast cancer, we were able to detect the metabolic differences among tumors of different metastatic potential and between norm...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4614-7411-1_32

    authors: Xu HN,Kadlececk S,Pullinger B,Profka H,Cai K,Hariharan H,Rizi R,Li LZ

    更新日期:2013-01-01 00:00:00

  • Evaluation of Functional Hyperemia Using NIRTRS Without the Influence of Fat Layer Thickness.

    abstract::Fat layer thickness (FLT) affects near infrared spectroscopy (NIRS) measurement. The aim of this study was to determine an indicator of muscle function with less influence of FLT, even without normalization, by comparing muscle O2 dynamics during exercise in subjects with similar physical characteristics except for FL...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-319-91287-5_16

    authors: Endo T,Kime R,Fuse S,Watanabe T,Murase N,Kurosawa Y,Hamaoka T

    更新日期:2018-01-01 00:00:00

  • NOD-like receptors--pivotal guardians of the immunological integrity of barrier organs.

    abstract::NOD-like receptors (NLRs) exert pivotal roles in innate immunity as sensors of exogenous or endogenous cellular danger signals. The NLR protein family has a characteristic domain architecture comprising a central nucleotide binding and oligomerization domain (NOD), an N-terminal effector binding domain and C-terminal ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4419-0901-5_3

    authors: Rosenstiel P,Schreiber S

    更新日期:2009-01-01 00:00:00

  • Neuropilins as Semaphorin receptors: in vivo functions in neuronal cell migration and axon guidance.

    abstract::After the initial discovery of neuropilin-1 as an epitope on axons recognized by a monoclonal antibody, neuropilins were rediscovered in the search for receptors mediating the repulsive actions of class 3 Semaphorins, notably Sema3A. Neuropilins are the ligand binding moieties in the class 3 Semaphorin receptor comple...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:

    authors: Bagri A,Tessier-Lavigne M

    更新日期:2002-01-01 00:00:00