Abstract:
AIM:To describe thrombosis of the sinus durae matris (TSDM) in lymphomas. SUBJECTS AND METHODS:402 patients with Hodgkin lymphoma were treated using the BEACOPP-14 protocol in 2006 to 2013. Thrombotic events occurred in 6% of the patients, including 3 (0.8%) who developed brain magnetic resonance imaging-verified TSDM. RESULTS:TSDM developed in 3 women aged 17, 18, and 25 years during 3-6 chemotherapy cycles involving glucocorticosteroids in a dose of 80 mg/m2 on days 1-7 and an oral contraceptive used continuously for 1.5-3 months. The symptoms of thrombosis were severe headache; 2 patients had convulsive syndrome with short-term loss of consciousness. Anticoagulant therapy with intravenous heparin 20,000--24,000 U/day led to thrombus recanalization within 4-10 days. No rethromoboses were observed during a subsequent follow-up. CONCLUSION:The BEACOPP-14 treatment in young women with Hodgkin lymphoma who continuously take oral contraceptives should be combined with anticoagulant therapy, by monitoring their coagulogram.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Shitareva IV,Moiseeva TN,Al'-Radi LS,Margolin OV,Khlavno AB,Iatsyk GA,Kravchenko SKsubject
Has Abstractpub_date
2014-01-01 00:00:00pages
68-72issue
7eissn
0040-3660issn
2309-5342journal_volume
86pub_type
杂志文章abstract::Aortocoronary shunting was performed in 15 patients with unstable and early postinfarction angina pectoris. Coronarography revealed an isolated lesion of a coronary artery in all the patients. Two years after the operation the patients had no angina pectoris; no myocardial infarctions occurred. ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The paper describes Russia's first diagnosed case of Erdheim--Chester disease (systemic histiocytosis) in a 65-year-old man who has been long treated for Ormond's disease (idiopathic retroperitoneal fibrosis). It also gives the data available in the literature on the pathogenetic components of these diseases and on th...
journal_title:Terapevticheskii arkhiv
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::Despite the success in increasing the effectiveness of treatment of arterial hypertension (AH), frequency of achieving target levels of blood pressure (BP) in hypertensive patients and the scope of their regular supervision in most countries of the world, including in the Russian Federation are insufficient. Modern te...
journal_title:Terapevticheskii arkhiv
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journal_title:Terapevticheskii arkhiv
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
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更新日期:1984-01-01 00:00:00
abstract::The paper provides current views on the structure and functional activity of bacterial toxins, clinical use of bacterial lipopolysaccharides and their derivatives as immunostimulators, review investigations on the introduction of the botulinic toxin A in ophthalmological and neurological practice, on production of imm...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:1986-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
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更新日期:2016-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
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更新日期:2016-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
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journal_title:Terapevticheskii arkhiv
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,多中心研究
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更新日期:2018-02-15 00:00:00