Abstract:
:Experimental design is a form of process analysis in which certain factors are selected to obtain the desired responses of interest. It may also be used for the determination of the effects of various independent factors on a dependent factor. The bioengineering discipline includes many different areas of scientific interest, and each study area is affected and governed by many different factors. Briefly analyzing the important factors and selecting an experimental design for optimization are very effective tools for the design of any bioprocess under question. This review summarizes experimental design methods that can be used to investigate various factors relating to bioengineering processes. The experimental methods generally used in bioengineering are as follows: full factorial design, fractional factorial design, Plackett-Burman design, Taguchi design, Box-Behnken design and central composite design. These design methods are briefly introduced, and then the application of these design methods to study different bioengineering processes is analyzed.
journal_name
Crit Rev Biotechnoljournal_title
Critical reviews in biotechnologyauthors
Keskin Gündoğdu T,Deniz İ,Çalışkan G,Şahin ES,Azbar Ndoi
10.3109/07388551.2014.973014subject
Has Abstractpub_date
2016-01-01 00:00:00pages
368-88issue
2eissn
0738-8551issn
1549-7801journal_volume
36pub_type
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