Abstract:
PURPOSES:To evaluate the feasibility of simultaneous quantification of liver iron concentration (LIC) and fat fraction (FF) using water-fat separation and quantitative susceptibility mapping (QSM). METHODS:Forty-five patients suspected of liver iron overload (LIO) were included. A volumetric interpolated breath-hold examination sequence for QSM and FF, a fat-saturated gradient echo sequence for R2*, a spin echo sequence for LIC measurements and MRS analyses for FF (FF-MRS) were performed. Magnetic susceptibility and FF were calculated using a water-fat separation method (FF-MRI). Correlation and receiver operating characteristic analyses were performed. RESULTS:Magnetic susceptibility showed strong correlation with LIC (rs=0.918). The optimal susceptibility cut-off values were 0.34, 0.63, 1.29 and 2.23 ppm corresponding to LIC thresholds of 1.8, 3.2, 7.0 and 15.0 mg/g dry weight. The area under the curve (AUC) were 0.948, 0.970, 1 and 1, respectively. No difference in AUC was found between susceptibility and R2* at all LIC thresholds. Correlation was found between FF-MRI and FF-MRS (R2=0.910). CONCLUSIONS:QSM has a high diagnostic performance for LIC quantification, similar to that of R2*. FF-MRI provides simultaneous fat quantification. Findings suggest QSM in combination with water-fat separation has potential value for evaluating LIO, especially in cases with coexisting steatosis. KEY POINTS:• Magnetic susceptibility showed strong correlation with LIC (r s =0.918). • QSM showed high diagnostic performance for LIC, similar to that of R 2* . • Simultaneously estimated FF-MRI showed strong correlation with MR-Spectroscopy-based FF (R 2 =0.910). • QSM combining water-fat separation has quantitative value for LIO with coexisted steatosis.
journal_name
Eur Radioljournal_title
European radiologyauthors
Lin H,Wei H,He N,Fu C,Cheng S,Shen J,Wang B,Yan X,Liu C,Yan Fdoi
10.1007/s00330-017-5263-4subject
Has Abstractpub_date
2018-08-01 00:00:00pages
3494-3504issue
8eissn
0938-7994issn
1432-1084pii
10.1007/s00330-017-5263-4journal_volume
28pub_type
杂志文章abstract:OBJECTIVES:We aimed to determine the frequency of isoattenuating insulinomas, to investigate their clinicopathological features and to assess their regional pancreatic perfusion characteristics. METHODS:Institutional review board approval was obtained, and patient informed consent was waived. From July 2010 to June 20...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4216-7
更新日期:2016-10-01 00:00:00
abstract::The aim of this study was to evaluate accuracy of 11 G vacuum-assisted percutaneous biopsy (VAPB) carried out on digital stereotaxic table, on breast non-palpable lesions (NPLs), non-visible by US. Prospective study on 132 consecutive NPLs (126 patients) not reliably found by US; 82% showed microcalcifications. Surgic...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-001-1168-2
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVES:To investigate image quality of triple-rule-out (TRO) computed tomography (CT) using a 320-row-detector CT system with substantially reduced contrast medium volume at 100 kV. METHODS:Forty-six consecutive patients with noncritical, acute chest pain underwent 320-row-detector CT using a two-step TRO protocol...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2088-4
更新日期:2011-07-01 00:00:00
abstract::Although spatial resolution of current MR angiography is excellent, temporal resolution has remained unsatisfactory. We evaluated clinical applicability of 2D thick-slice, contrast-enhanced subtraction MR angiography (2D-MR digital subtraction angiography) with sub-second temporal resolution in cerebrovascular occlusi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000584
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:Hepatic apparent diffusion coefficient (ADC) values and ADC-related indices were correlated with the Mayo risk score for primary biliary cirrhosis (MRSPBC) and METAVIR scores of liver specimens to determine the clinical and pathological significance of diffusion-weighted magnetic resonance imaging (DWMRI). ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3716-1
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To investigate the intra- and inter-observer reliability and agreement between gray-scale and Doppler ultrasound (US) and contrast-enhanced ultrasound (CEUS) in measuring ablated volume (Va) after radiofrequency ablation (RFA) for benign thyroid nodules. METHODS:A total of 173 patients with 190 benign thyroi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07398-0
更新日期:2020-10-31 00:00:00
abstract::The aim of this study was to assess radiomorphologic and clinical features of tracheal rupture due to blunt chest trauma. From 1992 until 1998 the radiomorphologic and clinical key findings of all consecutive tracheal ruptures were retrospectively analyzed. The study included ten patients (7 men and 3 women; mean age ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050080
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:Juvenile localized scleroderma (JLS) is a rare chronic autoimmune disease which can also affect bones and muscles. Nevertheless, muscle loss was not previously investigated in patients with JLS. Thus, the aim of this study was to retrospectively evaluate deep involvement and assess and quantify sarcopenia in...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-06764-2
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVES:This systematic review examines the agreement between assessed skeletal age by the Greulich and Pyle atlas (GP skeletal age) and chronological age. METHODS:We searched electronic databases until January 2017 for studies reporting GP skeletal age and confirmed chronological age in healthy individuals aged 10...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5718-2
更新日期:2019-06-01 00:00:00
abstract:KEY POINTS:• Identify, assure, and measure major sources of variability affecting the MRI-directed biopsy pathway for prostate cancer diagnosis.• Develop strategies to control and minimize variations that impair pathway effectiveness including the performance of main players and team working.• Assure end-to-end quality...
journal_title:European radiology
pub_type: 社论
doi:10.1007/s00330-020-07527-9
更新日期:2020-11-25 00:00:00
abstract:OBJECTIVES:To assess the value of a T1-3D black-blood turbo spin echo (TSE) sequence for the diagnosis of abdominal large vessel vasculitis (LVV). MATERIALS AND METHODS:The study included 20 patients with abdominal LVV and 17 controls, who underwent a 3T-MRI scan using a modified T1-3D volumetric isotropic TSE acquisi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06432-0
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:To investigate the diagnostic performance of reduced-dose CT with a hybrid iterative reconstruction (IR) algorithm for the detection of hypervascular liver lesions. METHODS:Thirty liver phantoms with or without simulated hypervascular lesions were scanned with a 320-slice CT scanner with control-dose (40 mA...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4687-6
更新日期:2017-07-01 00:00:00
abstract::The lower the heart rate the better image quality in multislice computed tomography (MSCT) coronary angiography. We prospectively assessed the influence of heart rate on per-patient diagnostic accuracy and image quality of MSCT coronary angiography and compared adaptive multisegment and standard halfscan reconstructio...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0685-z
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVES:To investigate safety and diagnostic value of 1.5-T MRI in carriers of conventional pacemaker (cPM) or conventional implantable defibrillator (cICD). METHODS:We prospectively compared cPM/cICD-carriers undergoing MRI (study group, SG), excluding those device-dependent or implanted <6 weeks before enrolment ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5098-z
更新日期:2018-06-01 00:00:00
abstract::The aim of our study was to evaluate the use of a 1-molar gadolinium chelate (gadobutrol) as an alternative contrast medium for computed tomography angiography (CTA) exams of the aorta. CTA exams of the thoracic and/or abdominal aorta were performed on 15 patients with contraindications for the use of iodine who were ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0590-5
更新日期:2007-09-01 00:00:00
abstract::We here introduce a digital scanning method for determining leg length and angles. The leg length and angle measurements, image quality and radiation dose were evaluated. A composite overview image was reconstructed from a series of individual images. In 45 overview images, the total leg length and the femoro-tibial a...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2352-y
更新日期:2005-01-01 00:00:00
abstract::Cardiovascular intervention, using MRI guidance, is challenging for clinical applications. Real-time imaging sequences with high spatial resolution are needed for monitoring intramyocardial delivery of drug, gene, or stem cell therapies. New generation MR scanners make local intramyocardial and vascular wall therapies...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-004-2622-8
更新日期:2005-05-01 00:00:00
abstract::We report the case of a man in which a Hodgkin's lymphoma involved the ureter as the very first clinical situs of the disease. Ureteral involvement in lymphomas is very rare (0.86%-7% and 1%-16%, found in two studies, respectively, of cases of patients with lymphoma examined post mortem) and when it does occur it is s...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050677
更新日期:1999-01-01 00:00:00
abstract::Advanced bronchial carcinomas by means of perfusion and peak enhancement using dynamic contrast-enhanced multislice CT are characterized. Twenty-four patients with advanced bronchial carcinoma were examined. During breathhold, after injection of a contrast-medium (CM), 25 scans were performed (1 scan/s) at a fixed tab...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2288-2
更新日期:2004-07-01 00:00:00
abstract::Magnetic resonance (MR) arthrography has gained increasing popularity as a diagnostic tool in the assessment of intra-articular derangements. Its role has been studied extensively in the shoulder, but it also has been explored in the hip, elbow, knee, wrist and ankle. This article reviews the current role of direct MR...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-004-2449-3
更新日期:2004-11-01 00:00:00
abstract::The appearances of knee injuries on MR imaging are less well documented in children than adults. Some patterns of injury are shared by both groups of patients, e. g. meniscal damage. The frequency of specific injuries may differ, e. g. anterior cruciate ligament (ACL) tear. Congenital abnormality, coexistent pathology...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050284
更新日期:1997-01-01 00:00:00
abstract::The aim of this study was to evaluate ultrasound (US)-guided core-needle testicular biopsy. Twelve biopsies were performed in eleven patients, under US guidance using disposable 16- or 18-gauge needles, between April 2003 and October 2006. Details were entered on a database and records reviewed 9 months to 3 years aft...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-1072-0
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:Pre-therapeutic prediction of outcome is important for clinicians and patients in determining whether selective internal radiation therapy (SIRT) is indicated for hepatic metastases of colorectal cancer (CRC). METHODS:Pre-therapeutic characteristics of 100 patients with colorectal liver metastases (CRLM) tr...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3658-7
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVES:To explore and evaluate the feasibility of radiomics in stratifying nasopharyngeal carcinoma (NPC) into distinct survival subgroups through multi-modalities MRI. METHODS:A total of 658 patients (training cohort: 424; validation cohort: 234) with non-metastatic NPC were enrolled in the retrospective analysis...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06075-1
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVES:To compare videofluoroscopy that included a tablet test with impedance planimetry (EndoFLIP®) for the evaluation of oesophageal stenosis in patients with dysphagia. METHODS:In 56 patients, videofluoroscopic examinations following the transit of a 14-mm tablet were retrospectively reviewed and correlated wit...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4516-y
更新日期:2017-04-01 00:00:00
abstract::Digital imaging (digital image intensifier radiography, storage phosphor/selenium radiography) is increasingly becoming commonplace in radiology departments for diagnostic purposes. Despite 10 years of experience, the advantages and disadvantages of those methods are still heavily discussed among users, financiers and...
journal_title:European radiology
pub_type: 杂志文章
doi:
更新日期:1997-02-21 00:00:00
abstract::The purpose of this study was to evaluate the scope of sub-millimeter collimation reconstruction parameters using 16-row computer tomography and ECG triggering on image quality in virtual bronchoscopy. Thirty-two patients (5 women, 27 men, mean age 66.6+/-1.4) who had been admitted for coronary artery bypass graft sur...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00330-004-2325-1
更新日期:2004-08-01 00:00:00
abstract::Multidetector computed tomography (CT) plays an important role in the detection, risk stratification and prognosis evaluation of acute pulmonary embolism. This review will discuss the technical improvements for imaging peripheral pulmonary arteries, the methods of assessing pulmonary embolism severity based on CT find...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-015-3679-2
更新日期:2015-09-01 00:00:00
abstract::The purpose was to evaluate whether B-flow can improve the ultrasonographic diagnosis of preocclusive stenosis and occlusion of the internal carotid artery (ICA) compared with colour-coded Doppler and power Doppler. Ninety patients with occlusions or preocclusive stenoses of the ICA suspected by Doppler sonography wer...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0285-3
更新日期:2007-02-01 00:00:00
abstract::The aim of this study was to describe a new sonographic sign of bone fracture and to determine if it can be helpful in decreasing the number of missed fractures of the proximal humerus. Ultrasound (US) of the shoulder was performed in 57 consecutive patients with shoulder pain and/or disability following trauma. All c...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0331-1
更新日期:2007-03-01 00:00:00