Abstract:
OBJECTIVE:To investigate the safety and effectiveness of the application of high-volume hemofiltration (HVHF) in children with sepsis combined with acute kidney injury. PATIENTS AND METHODS:A total of 76 child patients were enrolled and randomly divided equally (n=38) into control and the observation groups respectively. The control group received conventional volume hemofiltration (the ultrafiltration rate of 35-50 ml/kg/h), and the observation group received HVHF (50-100 ml/kg/h). RESULTS:The serum Interleukin-6 (IL-6), Tumor Necrosis Factor-a (TNF-α) and creatinine levels were significantly lower in the observation group than the control group at 6 h, 12 h, 24 h and 48 h of hemofiltration (p<0.05). The efficacy rate of treatment was improved. The mortality rate and incidence rate of complications were decreased, and the treatment course was significantly shortened (p<0.05). CONCLUSIONS:The application of HVHF in children with sepsis combined with acute kidney injury has a better safety and effectiveness.
journal_name
Eur Rev Med Pharmacol Scijournal_title
European review for medical and pharmacological sciencesauthors
Meng SQ,Yang WB,Liu JG,Yuan JY,Zhang K,Ding WY,Yang SQ,Liu JHdoi
10.26355/eurrev_201802_14298subject
Has Abstractpub_date
2018-02-01 00:00:00pages
715-720issue
3eissn
1128-3602issn
2284-0729journal_volume
22pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:Chronic Heart Failure (CHF) is associated with multi-hormonal derangement depicting a prevalence of catabolic vs. anabolic axes. Moreover, thyroid adaption is characterized by the reduced conversion of thyroxine to the active hormone triiodothyronine. On the other hand, hormones modulate synthesis and utiliza...
journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章,评审
doi:10.26355/eurrev_201806_15279
更新日期:2018-06-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
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journal_title:European review for medical and pharmacological sciences
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pub_type: 杂志文章,评审
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更新日期:2015-12-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2010-09-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章
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更新日期:2013-04-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章,随机对照试验
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journal_title:European review for medical and pharmacological sciences
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