Abstract:
:To date, relatively little is known about the economic and medical impact of Lyme borreliosis (LB) on European health care systems, especially for the inpatient sector. This retrospective analysis is based on data provided for the years 2007-2011 by a German statutory health insurance company (DAK-Gesundheit) covering approximately 6 million insured. Total cost was calculated for a 1-year period both from the third-party payers and from the societal perspective, respectively. In our cohort the incident diagnosis of LB was coded for 2163 inpatient cases during the years 2008-2011. The median inpatient time was 9 days resulting in a median direct medical cost per hospital stay of 3917€ for adolescents and 2843€ for adults. Based on extrapolation of our findings to the German population, we would expect an average hospital admission of 5200 adults and 2300 adolescents (<18 years) for LB treatment incurring direct medical costs of more than 23 million Euro annually. The annual indirect costs due to loss of productivity would add up to more than 7 million Euro as assessed by the human capital method. Cases tended to accumulate between June and September with remarkable changes in disease manifestations in the course of the year documented in the coded secondary diagnoses. Also specific differences in the disease pattern of adolescents and adults became obvious. Age-specific incidence showed male predominance and a bimodal distribution. Incidence was highest in children aged between 3 and 17 (highest mean incidence of 29 cases/100,000 inhabitants in 6-9 year olds) with a second peak in 60-79 year old individuals. During the study period the nationwide inpatient incidence was 9/100,000 with marked regional variability. In summary, our study is one of the first European investigations on hospital care for LB inpatients and identifies LB as a possibly underestimated socioeconomic factor for health care in Germany.
journal_name
Ticks Tick Borne Disjournal_title
Ticks and tick-borne diseasesauthors
Lohr B,Müller I,Mai M,Norris DE,Schöffski O,Hunfeld KPdoi
10.1016/j.ttbdis.2014.09.004subject
Has Abstractpub_date
2015-02-01 00:00:00pages
56-62issue
1eissn
1877-959Xissn
1877-9603pii
S1877-959X(14)00188-5journal_volume
6pub_type
杂志文章abstract::Acaricide resistance is one of the greatest threats to sustainable and effective control of vector ticks worldwide. The amitraz resistance status in cattle tick, Rhipicephalus microplus populations collected from 18 districts of Punjab in north-western India were characterized using bioassay and molecular assays. The ...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101578
更新日期:2021-01-01 00:00:00
abstract::The aim of this study was to describe the dynamics of the long-legged bat tick Ixodes vespertilionis infestation on the lesser horseshoe bat Rhinolophus hipposideros in 2 nursery colonies roosting in attics. Out of a total of 810 lesser horseshoe bats examined, 217 (26.8%) were found to be infested with a total of 464...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2013.08.006
更新日期:2014-02-01 00:00:00
abstract::The hard tick Ixodes ricinus is the principal vector of Lyme borreliosis (LB) group spirochaetes in Europe, but it also transmits a large number of other microbial pathogens that are of importance to animal and human health. Here, we characterise geographically distinct populations of this important ectoparasite based...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2013.10.001
更新日期:2014-03-01 00:00:00
abstract::Brazilian spotted fever (BSF) is the deadliest rickettsiosis in the world. Although the epidemiology of the disease has been established in Brazil, there are still limited data available on distribution of tick vectors and tick species parasitizing humans in the country, particularly in Paraná State. The State of Para...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101510
更新日期:2020-11-01 00:00:00
abstract::Theileriosis is a disease of domesticated animals in tropical and subtropical countries and causes significant reductions in livestock productivity. The arid region of Punjab in Pakistan is notorious for the presence of the vector tick (Acari: Ixodidae) and tick-borne diseases, such as theileriosis and babesiosis. The...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2018.03.028
更新日期:2018-05-01 00:00:00
abstract::The protozoan Hepatozoon canis, which is transmitted via ingestion of infected ticks by canine hosts, is not endemic to mid-latitude regions in Europe. Its distribution is supposed to be linked to the occurrence of its primary tick vector Rhipicephalus sanguineus. A young male golden jackal (Canis aureus) found as roa...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2012.10.040
更新日期:2013-02-01 00:00:00
abstract::Haemaphysalis longicornis Neumann is an invasive tick species that has recently been detected in the eastern United States. We designed field studies to monitor the population dynamics of H. longicornis over a year (2019) in New Jersey, and to assess the efficacy of a pyrethroid acaricide (lambda-cyhalothrin) in contr...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101581
更新日期:2021-01-01 00:00:00
abstract::The entomopathogenic fungus Metarhizium anisopliae is used as a biological pest control agent against various arthropod species, including ticks. However, the efficacy depends on tick species, tick stage and fungus strain. We studied the effect of M. anisopliae on engorged larvae and nymphs of Ixodes ricinus, the most...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2016.03.010
更新日期:2016-07-01 00:00:00
abstract::Rickettsia amblyommatis is widely distributed in the Americas, and has been reported to infect different species of ticks within its distribution. In Panama, R. amblyommatis is the most common Rickettsia and its presence was molecularly detected in nine species of ticks and one flea species. This work described the is...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101597
更新日期:2021-01-01 00:00:00
abstract::There are 4 major human-biting tick species in the northeastern United States, which include: Amblyomma americanum, Amblyomma maculatum, Dermacentor variabilis, and Ixodes scapularis. The black bear is a large mammal that has been shown to be parasitized by all the aforementioned ticks. We investigated the bacterial i...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2012.12.002
更新日期:2013-04-01 00:00:00
abstract::Ixodes affinis Neumann (1899) and Ixodes scapularis Say (1821) are tick vectors of the etiologic agent of Lyme disease, Borrelia burgdorferi sensu stricto. Ixodes affinis and I. scapularis are morphologically very similar, and as they are sympatric in the mid- and south-Atlantic U.S. coastal states, their accurate ide...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2013.08.003
更新日期:2014-02-01 00:00:00
abstract::Ehrlichiosis is a tick-borne bacterial disease caused by pathogens of the Ehrlichia genus. Although human ehrlichiosis has not been reported in Japan, Ehrlichia spp., which are closely related to Ehrlichia chaffeensis, were detected in several species of ixodid ticks. In this study, the presence of Ehrlichia spp. in t...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2018.11.010
更新日期:2019-02-01 00:00:00
abstract::This study was aimed to know epidemiological aspects of Borrelia spp. in a protected urban area of Buenos Aires city, Argentina, where thousands of people visit this area for recreational purposes. Ticks were collected from vegetation, birds and dogs. Three hundred and forty birds belonging to 43 species, 41 genera, 1...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2019.101282
更新日期:2019-10-01 00:00:00
abstract::Ticks are important vectors of pathogens affecting humans and animals worldwide. They do not only carry pathogens but diverse commensal and symbiotic microorganisms are also present in ticks. A molecular screening for tick-borne pathogens and endosymbionts was carried out in Ixodes ricinus, Dermacentor reticulatus and...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2018.05.002
更新日期:2018-07-01 00:00:00
abstract::Rhipicephalus microplus and Rhipicephalus decoloratus species occur in regions with savannah and temperate climates, typically in grassland and wooded areas used as cattle pasture. Both species are associated with the transmission of Anaplasma and Babesia spp., impacting livestock health and quality of livestock-assoc...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2016.01.007
更新日期:2016-06-01 00:00:00
abstract::Ticks collected from mustelids from four counties in Maine and one in New Hampshire were identified after harvest. Of the 18 fishers Martes pennanti Erxleben, two mink Neovison vison Schreber, and one long-tailed weasel Mustela frenata Lichtenstein, 589 ticks were collected and identified. They were identified as, in ...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2014.02.001
更新日期:2014-06-01 00:00:00
abstract::Canine vector borne diseases include a variety of illnesses affecting domestic dogs worldwide. Clinical abnormalities are often nonspecific during rickettsial infections, and coinfections caused by other tick-transmitted agents may be common. The aim of this study was to validate a differential serological assay for t...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2012.10.024
更新日期:2012-12-01 00:00:00
abstract::Equine piroplasmosis is one of the most significant tick-borne disease of equids. The prevalence of this disease in donkeys of semi-arid Kenya remains largely unexplored. The primary objective of this study was to demonstrate the extent to which donkeys in Nuu division, Kenya have been exposed to the haemoprotozoans B...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.05.015
更新日期:2015-07-01 00:00:00
abstract::This study is the first report about the prevalence of tick-borne pathogens, as well as their (co-)infection rates, in the museum-archived I. ricinus female ticks collected in Moldova in 1960. A total of 16.7% (21/126) ticks was mono-infected. Borrelia burgdorferi sensu stricto was revealed as the most abundant specie...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2012.12.004
更新日期:2013-06-01 00:00:00
abstract::As ticks spend most of their time off-host, the environment is a major selective force of these parasites. In fact, human impact on landscapes has favored a minority of tick species which became well-known pests. However, this is an ongoing process and novel pests may arise. We herein report a surrogate life cycle of ...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2012.06.002
更新日期:2012-09-01 00:00:00
abstract::Tick-borne diseases (TBD) occur in many temperate countries and are economically important in most tropical and subtropical areas, affecting dairy and beef cattle, as well as small ruminants. Four major tick-borne diseases have been detected in eastern and southern Africa: East Coast fever (ECF) caused by Theileria pa...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2019.101283
更新日期:2020-01-01 00:00:00
abstract::Lyme disease is the most commonly reported vector-borne illness in the United States. Since the institution of Nationally Notifiable surveillance efforts for Lyme disease in the United States in 1991, there has been a consistent increase in the number of reported cases. Thus, the need for targeted prevention strategie...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.12.003
更新日期:2016-03-01 00:00:00
abstract::This work was performed to evaluate the presence of Borrelia in different populations of Ixodes pararicinus from northwestern Argentina (Jujuy, Salta and Tucumán provinces). Questing adults and nymphs of I. pararicinus were collected from vegetation, and I. pararicinus nymphs were also collected on birds. Eighty-two t...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2017.02.008
更新日期:2017-06-01 00:00:00
abstract::Borrelia spp. are agents of Lyme disease and relapsing fever, diseases which use Ixodes hard ticks and Ornithodoros soft ticks, respectively, as primary vectors. Some relapsing fever spirochetes, such as B. miyamotoi, are also found in hard ticks. To date, no Borrelia sp. is known to use the hard tick, Amblyomma macul...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2014.02.004
更新日期:2014-06-01 00:00:00
abstract::Anaplasma phagocytophilum is an obligate intracellular and tick-transmitted bacterium, which causes granulocytic anaplasmosis in animals and humans. Although infection with A. phagocytophilum in domestic animals and vector ticks is documented, there is sparse information on the occurrence of A. phagocytophilum in wild...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2013.11.001
更新日期:2014-04-01 00:00:00
abstract::Rickettsial pathogens cause diseases that vary in severity and clinical presentation. Rickettsia species transmitted by ticks are mostly classified within the spotted fever group of rickettsiae (SFGR) and are often associated with febrile diseases. Preliminary studies have detected three human-pathogenic SFGR from tic...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101470
更新日期:2020-09-01 00:00:00
abstract::Cytauxzoonosis is an emerging, tick-transmitted, protozoan disease affecting domestic and wild felids and caused by Cytauxzoon felis, Cytauxzoon manul and Cytauxzoon spp. This study aimed to determine the presence of infection with Cytauxzoon spp. in Felis silvestris silvestris in Italy, in order to enhance the compre...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2016.04.003
更新日期:2016-07-01 00:00:00
abstract::Anaplasma phagocytophilum is an intracellular rickettsial pathogen transmitted by Ixodes spp. ticks, which causes granulocytic anaplasmosis in humans, horses and dogs and tick-borne fever (TBF) in ruminants. In the United States, human granulocytic anaplasmosis (HGA) is highly prevalent while TBF has not been reported...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.07.001
更新日期:2015-09-01 00:00:00
abstract::A total of 705 rodents from Myodes, Microtus, and Apodemus genera, 396 adult questing Ixodes persulcatus, and 115 Ixodes larvae and nymphs taken from rodents (and then molted under laboratory conditions to nymphs and adults) were collected in 2013-2018 in Omsk province, Russian Siberia, and examined for the presence o...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101499
更新日期:2020-09-01 00:00:00
abstract::The current need of identification of a new acaricidal agent which is acceptable to public as environmentally safe is a daring task. Use of herbal acaricides is such an alternative. Most of the herbal extracts or fractions are dissolved in polar or non-polar solvents or detergents before tested for acaricidal activity...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2011.04.001
更新日期:2011-09-01 00:00:00