Abstract：
OBJECTIVE:To provide a systematic review of the existing literature on health consequences of vaporing of electronic cigarettes (ECs). METHODS:Search in: PubMed, EMBASE and CINAHL. INCLUSION CRITERIA:Original publications describing a health-related topic, published before 14 August 2014. PRISMA recommendations were followed. We identified 1101 studies; 271 relevant after screening; 94 eligible. RESULTS:We included 76 studies investigating content of fluid/vapor of ECs, reports on adverse events and human and animal experimental studies. Serious methodological problems were identified. In 34% of the articles the authors had a conflict of interest. Studies found fine/ultrafine particles, harmful metals, carcinogenic tobacco-specific nitrosamines, volatile organic compounds, carcinogenic carbonyls (some in high but most in low/trace concentrations), cytotoxicity and changed gene expression. Of special concern are compounds not found in conventional cigarettes, e.g. propylene glycol. Experimental studies found increased airway resistance after short-term exposure. Reports on short-term adverse events were often flawed by selection bias. CONCLUSIONS:Due to many methodological problems, severe conflicts of interest, the relatively few and often small studies, the inconsistencies and contradictions in results, and the lack of long-term follow-up no firm conclusions can be drawn on the safety of ECs. However, they can hardly be considered harmless.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Pisinger C,Døssing Mdoi
10.1016/j.ypmed.2014.10.009subject
Has Abstractpub_date
2014-12-01 00:00:00pages
248-60eissn
0091-7435issn
1096-0260pii
S0091-7435(14)00373-9journal_volume
69pub_type
杂志文章,评审abstract：BACKGROUND:Although the disease consequences of cigarette smoking are well documented, smoking may also be associated with increased risk of injury. Our purpose is to provide an overview of this potential association. METHODS:We conducted a literature review. RESULTS:Cigarettes are the leading cause of death from fir...
journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1006/pmed.1994.1070
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVES:This study explores the predisposing, enabling, and need-based factors associated with parents' or guardians' decision to have their child initiate, continue, and complete the human papillomavirus (HPV) vaccine. METHODS:Parents and guardians of children between the ages of 9 and 17years who completed the 20...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2016.01.010
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:Elevated total homocysteine (tHcy) levels (>/= 15 micromol/L), resulting from enzyme or vitamin deficiency, increase risk for cardiac, cerebral, and peripheral vascular disease. This study examines tHcy levels in an Israeli population and the relationship to vitamin status and disease. The need for screening...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2003.09.001
更新日期：2003-12-01 00:00:00
abstract：:The Cancer Information Service (CIS) was established in 1975 by the National Cancer Institute (NCI) to provide accurate, up-to-date information about cancer to the nation. Although the CIS has in the past served as a venue for cancer communications research, up until very recently the research capacity of the CIS was ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1998.0245
更新日期：1998-09-01 00:00:00
abstract：OBJECTIVE:Treatment delays in breast cancer are generally thought to affect prognosis but the impact on survival remains unclear. Indicators for breast cancer care include time to primary treatment. The purpose of this study was to evaluate whether time to primary treatment (TPT) in breast cancer impacts survival. MET...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2012.12.001
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:We examined the effect of sociodemographic factors on the receipt of mammography, colorectal cancer screening, and influenza vaccinations by women enrolled in two Medicare+Choice health plans. METHODS:Administrative and survey data for 2,698 female health plan members was analyzed using multivariate logisti...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.02.041
更新日期：2004-10-01 00:00:00
abstract：BACKGROUND:Findings from the Life Span Study (LSS) of the health effects of exposure to atomic bomb radiation have documented a strong dose-response relation between radiation exposure and breast cancer incidence. PURPOSE:We analyzed data from the LSS cohort to identify nonradiation risk factors for breast cancer and ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1996.9979
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Despite the cost-effectiveness of physician smoking cessation counseling, many physicians do not adhere to current clinical practice guidelines. METHODS:A cross-sectional mail survey was conducted in a random sample of general practitioners in Montreal to document cessation-counseling practices and identify...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.2001.0937
更新日期：2001-12-01 00:00:00
abstract：:Youth who experience alcohol-related problems are at increased risk for developing alcohol dependence. Identifying factors associated with adolescent alcohol-related problems is essential, but most studies have focused on risk factors or a limited number of protective factors, with little attention to sex differences....
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2019.03.042
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:To evaluate BMI and direct measures of body fat (BF) and lean body mass (LBM) in relation to fasting serum lipid profiles in a large Chinese population based twin sample using a monozygotic (MZ) co-twin analysis. METHODS:Adiposity measures collected 1998-2000 on 987 MZ female 20-60 year old twin pairs (n=197...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2007.07.014
更新日期：2007-11-01 00:00:00
abstract：:A meta-analysis on Active Video Games (AVG) as a rehabilitative tool does not appear to be available. This meta-analytic review synthesizes the effectiveness of AVGs on patients' rehabilitative outcomes. Ninety-eight published studies on AVGs and rehabilitation were obtained in late 2015 with 14 meeting the following ...
journal_title：Preventive medicine
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.ypmed.2016.12.003
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the effects of a lifestyle intervention and a structured exercise intervention on physical activity in older adults. METHOD:Participants were randomly assigned to a lifestyle intervention (n=60), including an individualized home-based program supported by phone calls, or to a structured intervent...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ypmed.2008.02.017
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Whereas self-efficacy expectations have been identified as important determinants of exercise participation patterns, little empirical work that examines efficacy expectations as outcomes of exercise participation or their theoretical relationship to other psychological outcomes associated with exercise has ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1995.1053
更新日期：1995-07-01 00:00:00
abstract：:This study identified barriers and facilitators of repeat participation in mammography and breast physical examination among women ages 50 years and over. Telephone interviews were conducted with 910 women in this age group. Forty percent of respondents had never had a mammogram. Only 38% had had one in the past 12 mo...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(90)90028-i
更新日期：1990-05-01 00:00:00
abstract：:Smoking-cessation programs at the worksite hold the potential to reduce the national prevalence of smoking. This article presents the 2-year results of a broad-spectrum smoking-cessation initiative that was part of the comprehensive Johnson & Johnson LIVE FOR LIFE wellness program. In a quasi-experimental design, four...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(88)90069-2
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:To explore longitudinal (demographic, socioeconomic, health and psychological) determinants of walking, moderate and vigorous physical activity. METHODS:The sample included 11,133 adult participants (5913 women; 5220 men) taken from the Household, Income and Labour Dynamics in Australia (HILDA) project. Demo...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2015.07.014
更新日期：2015-09-01 00:00:00
abstract：:Ethnic groups in the United States exhibit different patterns of cardiovascular disease and cancer morbidity and mortality. This has, in part, been attributed to differences in dietary intake. However, there is limited comparative information available regarding the dietary patterns of whites, blacks, and Hispanics re...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(88)90055-2
更新日期：1988-09-01 00:00:00
abstract：:The relationship between coffee consumption and serum cholesterol was examined in the comparison group of a case-control study of myocardial infarction involving 642 patients from various Italian regions who were hospitalized for diseases having no relationship to cardiovascular disease risk factors. Overall mean tota...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1993.1018
更新日期：1993-03-01 00:00:00
abstract：OBJECTIVE:We examined whether childhood candy cigarette use was associated with adult tobacco smoking. METHODS:25,887 U.S. adults from the Harris Poll Online (HPOL) were surveyed about current smoking status from November 2005 to May 2006. Respondents were randomly assigned to a yes/no item or a dose-response scale to...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2007.04.006
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVE:To determine the association between self-reported diabetes and posttraumatic stress disorder (PTSD) among adults in the community and to investigate the specificity of this link. METHOD:Data were drawn from the National Comorbidity Survey (NCS), a household probability sample of adults ages 15-54 in the Uni...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.07.013
更新日期：2005-05-01 00:00:00
abstract：BACKGROUND:This study brings together the fragmentary knowledge on social influence factors related to smoking cessation. An inventory of social influence variables shows six social influence factors. With the exception of descriptive norm, most of these are rarely studied in the context of smoking cessation. METHODS:...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.09.040
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:The epidemiologic observation that physical activity reduces the risk for hypertension has only been made for white men who self-reported hypertension. This study examined physical activity and clinically determined incident hypertension in black and white men and women of the Atherosclerosis Risk in Communi...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1998.0431
更新日期：1999-03-01 00:00:00
abstract：:A prospective analysis was used to test whether respiratory impairment or the presence of respiratory symptoms predicts 5-year cigarette smoking cessation in a sample of 1,118 U.S. white, male, underground coal miners. Miners were examined in 1977 and re-examined in 1982 by NIOSH, and all miners with test abnormalitie...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(85)90033-7
更新日期：1985-03-01 00:00:00
abstract：BACKGROUND:This paper describes decisions about the experimental design for the Youth, Osteoporosis, and Understanding Total Health Project (YOUTH), a trial designed to test the efficacy of a health plan-based lifestyle intervention for increasing bone mineral density among adolescent women 14 to 16 years of age. METH...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ypmed.2004.04.010
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:The North American Guidelines for Children's Agricultural Tasks were developed to assist farm parents in assigning developmentally appropriate and safe work to children aged 7 to 16 years. The purpose of this study was to compare the efficacy of the standard dissemination strategy with an enhanced, multiphas...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1006/pmed.2002.1051
更新日期：2002-08-01 00:00:00
abstract：:As a major public health issue, human trafficking (HT) affects individuals, families, communities, and societies around the world. A public health approach to combating HT has been advocated. Such an approach seeks to prevent HT by engaging diverse stakeholder groups in addressing risk factors at multiple levels. As a...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2018.07.006
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:The obesity paradox in patients with cardiovascular disease (CVD) remains unexplained. We examined the role of self-rated health, behavioral and objectively assessed risk factors, in order to further explore mechanisms that might influence the association between body mass index (BMI) and mortality in CVD pat...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2013.02.012
更新日期：2013-07-01 00:00:00
abstract：OBJECTIVE:Our primary objective was to determine whether a novel 'active school' model--Action Schools! BC--improved the cardiovascular disease (CVD) risk profile in elementary-school children. Our secondary objective was to determine the percentage of children with elevated CVD risk factors. METHODS:We undertook a cl...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ypmed.2008.02.020
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Studies on children and adolescents suggest a large increase in the role of snacking; however, little is know about changes in the snacking behavior of young adults. METHODS:USDA's nationally representative surveys from 1977-1978 to 1994-1996 are used to study snacking trends among 8,493 persons 19-29 years...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.2000.0817
更新日期：2001-04-01 00:00:00
abstract：:Of all the neurotoxins, lead is the longest known and best understood. Because we know so much about what it does, where it is, and what is required to remove it from the presence of children, lead poisoning should also be one of the easiest diseases to eradicate. Despite this, progress in the primary prevention of ch...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1994.1105
更新日期：1994-09-01 00:00:00
