当前位置： SCI文献检索 > Pediatrics and Neonatology期刊下所有文献 > Nonocclusive Mesenteric Ischemia after Chemotherapy in an Adolescent Patient with a History of Three Allogeneic Hematopoietic Stem Cell Transplantations for Acute Lymphoblastic Leukemia.

Nonocclusive Mesenteric Ischemia after Chemotherapy in an Adolescent Patient with a History of Three Allogeneic Hematopoietic Stem Cell Transplantations for Acute Lymphoblastic Leukemia.

Abstract：

:Nonocclusive mesenteric ischemia (NOMI) is induced by intestinal vasospasm without thromboembolic occlusion and is associated with high morbidity and mortality. The estimated overall incidence of autopsy-verified fatal NOMI is 2.0 cases/100,000 person-years; however, no pediatric or adolescent cases have yet been reported. An 18-year-old female was diagnosed with B-cell precursor acute lymphoblastic leukemia at the age of 10 years. Our patient received three allogeneic hematopoietic stem cell transplantations but experienced hematological relapse after each. She received combination therapy of prednisolone, L-asparaginase, vincristine, and bortezomib after the third relapse. On Day 16 after the initiation of chemotherapy, she developed NOMI; therefore, we performed a right-sided hemicolectomy on Day 27. Nonocclusive mesenteric ischemia should be considered during the differential diagnosis of intestinal complications after chemotherapy, even in pediatric and adolescent patients.

journal_name

Pediatr Neonatol

journal_title

Pediatrics and neonatology

authors

Hirabayashi K,Takatsuki M,Motobayashi M,Kurata T,Saito S,Shigemura T,Nakazawa Y,Sakashita K,Ishizone S,Ota H,Koike K

doi

10.1016/j.pedneo.2014.07.008

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

81-84

issue

1

eissn

1875-9572

issn

2212-1692

pii

S1875-9572(14)00165-X

journal_volume

58

pub_type

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