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Prolonged feeding difficulties after surgical correction of intestinal atresia: a 13-year experience.

Abstract：

BACKGROUND:Although surgical interventions for intestinal atresia are usually successful, oral feed intolerance could raise in certain cases. The aim of this study was to identify the factors that affect postoperative oral feed by retrospective analysis. METHODS:Neonates meeting the inclusion criteria, who were admitted at our center from 1 January 2000 to June 2013, were enrolled into this retrospective study. Time to establishment of full oral intake (TOI), length of hospital stay (LOS) were outcome measures. Univariate and multiple regression were used. RESULTS:Overall survival was 85.7%. Mean TOI was 20.4 ± 17.8 days, and mean LOS was 35.6 ± 44.8 days. Multivariate analysis confirmed a significant association with TOI for meconium peritonitis (P=0.024), luminal discrepancy between proximal and distal intestine (P=0.038), number of anastomoses (P=0.044), reportage of immature ganglion in proximal and/or distal intestine (P=0.029), and short bowel syndrome (P<0.001). Prematurity (P=0.022) increased the duration of hospitalization without affecting time to full oral intake. CONCLUSIONS:Meconium peritonitis, luminal discrepancy, number of anastomoses, reportage of immature ganglion, and short bowel syndrome were factors related to prolonged feeding difficulties. We advocate alertness for patients with these factors to reduce postoperative morbidity and treatment costs.

journal_name

J Pediatr Surg

journal_title

Journal of pediatric surgery

authors

Wang J,Du L,Cai W,Pan W,Yan W

doi

10.1016/j.jpedsurg.2014.06.010

subject

Has Abstract

pub_date

2014-11-01 00:00:00

pages

1593-7

issue

11

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(14)00401-1

journal_volume

49

pub_type

杂志文章

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