当前位置： SCI文献检索 > Cell Host & Microbe期刊下所有文献 > Pathogens' exploitation of the intestinal food web.

Pathogens' exploitation of the intestinal food web.

Abstract：

:Competition for nutrients is a key factor controlling pathogen colonization within the gastrointestinal tract. In this issue, Ferreyra et al. (2014) and Curtis et al. (2014) show that diverse enteric pathogens can exploit a metabolic byproduct from the commensal microbiota, succinate, to enhance their own virulence expression and proliferation.

journal_name

Cell Host Microbe

journal_title

Cell host & microbe

authors

Pham N TA,Lawley TD

doi

10.1016/j.chom.2014.11.012

subject

Has Abstract

pub_date

2014-12-10 00:00:00

pages

703-5

issue

6

eissn

1931-3128

issn

1934-6069

pii

S1931-3128(14)00428-4

journal_volume

16

pub_type

评论,杂志文章

相关文献

Cell Host & Microbe文献大全
  • A Ribose-Scavenging System Confers Colonization Fitness on the Human Gut Symbiont Bacteroides thetaiotaomicron in a Diet-Specific Manner.

    abstract：:Efficient nutrient acquisition in the human gut is essential for microbial persistence. Although polysaccharides have been well-studied nutrients for the gut microbiome, other resources such as nucleic acids and nucleosides are less studied. We describe several ribose-utilization systems (RUSs) that are broadly repres...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2019.11.009

    authors： Glowacki RWP,Pudlo NA,Tuncil Y,Luis AS,Sajjakulnukit P,Terekhov AI,Lyssiotis CA,Hamaker BR,Martens EC

    更新日期：2020-01-08 00:00:00

  • Homeostasis in infected epithelia: stem cells take the lead.

    abstract：:To maintain tissue homeostasis and avoid disease, epithelial cells damaged by pathogens need to be readily replenished, and this is mainly achieved by the activation of stem cells. In this Short Review, we discuss recent developments in the exciting field of host epithelia-pathogen interaction in Drosophila as well as...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2009.10.001

    authors： Pitsouli C,Apidianakis Y,Perrimon N

    更新日期：2009-10-22 00:00:00

  • Fungal Mimicry of a Mammalian Aminopeptidase Disables Innate Immunity and Promotes Pathogenicity.

    abstract：:Systemic fungal infections trigger marked immune-regulatory disturbances, but the mechanisms are poorly understood. We report that the pathogenic yeast of Blastomyces dermatitidis elaborates dipeptidyl-peptidase IVA (DppIVA), a close mimic of the mammalian ectopeptidase CD26, which modulates critical aspects of hemato...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2016.02.001

    authors： Sterkel AK,Lorenzini JL,Fites JS,Subramanian Vignesh K,Sullivan TD,Wuthrich M,Brandhorst T,Hernandez-Santos N,Deepe GS Jr,Klein BS

    更新日期：2016-03-09 00:00:00

  • Nonsense-mediated decay serves as a general viral restriction mechanism in plants.

    abstract：:(+)strand RNA viruses have to overcome various points of restriction in the host to establish successful infection. In plants, this includes RNA silencing. To uncover additional bottlenecks to RNA virus infection, we genetically attenuated the impact of RNA silencing on transgenically expressed Potato virus X (PVX), a...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2014.08.001

    authors： Garcia D,Garcia S,Voinnet O

    更新日期：2014-09-10 00:00:00

  • The oral commensal microbiota bites back through Nod1.

    abstract：:The mechanisms through which commensal bacterial populations cause inflammatory disease when shifted to dysbiotic community structures are poorly understood. Jiao et al. (2013) demonstrate that, in the case of inflammatory disease in the mouth, stimulation of the intracellular pattern recognition receptor Nod1 is a cr...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2013.05.001

    authors： Curtis M

    更新日期：2013-05-15 00:00:00

  • Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection.

    abstract：:Anti-helminth immunity involves CD4+ T cells, yet the precise effector mechanisms responsible for parasite killing or expulsion remain elusive. We now report an essential role for antibodies in mediating immunity against the enteric helminth Heligmosomoides polygyrus (Hp), a natural murine parasite that establishes ch...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2008.08.014

    authors： McCoy KD,Stoel M,Stettler R,Merky P,Fink K,Senn BM,Schaer C,Massacand J,Odermatt B,Oettgen HC,Zinkernagel RM,Bos NA,Hengartner H,Macpherson AJ,Harris NL

    更新日期：2008-10-16 00:00:00

  • Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus.

    abstract：:Virulence of emerging community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and other highly pathogenic S. aureus strains depends on their production of phenol-soluble modulin (PSM) peptide toxins, which combine the capacities to attract and lyse neutrophils. The molecular basis of PSM-stimulated ...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2010.05.012

    authors： Kretschmer D,Gleske AK,Rautenberg M,Wang R,Köberle M,Bohn E,Schöneberg T,Rabiet MJ,Boulay F,Klebanoff SJ,van Kessel KA,van Strijp JA,Otto M,Peschel A

    更新日期：2010-06-25 00:00:00

  • A Highly Pathogenic Avian H7N9 Influenza Virus Isolated from A Human Is Lethal in Some Ferrets Infected via Respiratory Droplets.

    abstract：:Low pathogenic H7N9 influenza viruses have recently evolved to become highly pathogenic, raising concerns of a pandemic, particularly if these viruses acquire efficient human-to-human transmissibility. We compared a low pathogenic H7N9 virus with a highly pathogenic isolate, and two of its variants that represent neur...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2017.09.008

    authors： Imai M,Watanabe T,Kiso M,Nakajima N,Yamayoshi S,Iwatsuki-Horimoto K,Hatta M,Yamada S,Ito M,Sakai-Tagawa Y,Shirakura M,Takashita E,Fujisaki S,McBride R,Thompson AJ,Takahashi K,Maemura T,Mitake H,Chiba S,Zhong G,Fan

    更新日期：2017-11-08 00:00:00

  • Microbiota-Dependent Priming of Antiviral Intestinal Immunity in Drosophila.

    abstract：:Enteric pathogens must overcome intestinal defenses to establish infection. In Drosophila, the ERK signaling pathway inhibits enteric virus infection. The intestinal microflora also impacts immunity but its role in enteric viral infection is unknown. Here we show that two signals are required to activate antiviral ERK...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2015.10.010

    authors： Sansone CL,Cohen J,Yasunaga A,Xu J,Osborn G,Subramanian H,Gold B,Buchon N,Cherry S

    更新日期：2015-11-11 00:00:00

  • NAGging Hexokinase PEPs up NLRP3.

    abstract：:Recognition of peptidoglycan is integral to detection of gram-positive bacterial pathogens. In a recent issue of Cell, Wolf et al. (2016) report that detection of the N-acetylglucosamine component of peptidoglycan by the glycolytic enzyme hexokinase activates the NLRP3 inflammasome, revealing an intriguing interplay b...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2016.07.017

    authors： Hampton H,Hutcheon C,Subramanian N

    更新日期：2016-08-10 00:00:00

  • Increased expression of LDL receptor-related protein 1 during human cytomegalovirus infection reduces virion cholesterol and infectivity.

    abstract：:In response to virus infection, cells can alter protein expression to modify cellular functions and limit viral replication. To examine host protein expression during infection with human cytomegalovirus (HCMV), an enveloped DNA virus, we performed a semiquantitative, temporal analysis of the cell surface proteome in ...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2012.05.012

    authors： Gudleski-O'Regan N,Greco TM,Cristea IM,Shenk T

    更新日期：2012-07-19 00:00:00

  • Bacterial Autophagy: How to Take a Complement.

    abstract：:Complement, a complex system of serum proteins, contributes to host defense through multiple mechanisms. In this issue of Cell Host & Microbe, Sorbara et al. (2018) discovered that cytosolic pathogens opsonized by complement are restricted by autophagy. This unexpected role for complement is important for cell-autonom...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2018.04.010

    authors： Sancho-Shimizu V,Mostowy S

    更新日期：2018-05-09 00:00:00

  • H. pylori's BabA Embraces Change.

    abstract：:Long before the cause was discovered, peptic ulcers were known to occur preferentially in individuals of certain blood groups. In this issue of Cell Host & Microbe, Moonens et al. (2016) perform structural analyses of the Helicobacter pylori adhesin BabA to determine how the bacteria discriminately bind different bloo...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2015.12.013

    authors： Sweeney EG,Guillemin K

    更新日期：2016-01-13 00:00:00

  • A critical role for SOCS3 in innate resistance to Toxoplasma gondii.

    abstract：:The innate and adaptive immune responses that confer resistance to the intracellular pathogen Toxoplasma gondii critically depend on IL-12 production, which drives interferon-γ (IFN-γ) expression. Certain cytokines can activate STAT3 and limit IL-12 production to prevent infection-associated immune pathology, but T. g...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2011.07.009

    authors： Whitmarsh RJ,Gray CM,Gregg B,Christian DA,May MJ,Murray PJ,Hunter CA

    更新日期：2011-09-15 00:00:00

  • Listeria Phages Induce Cas9 Degradation to Protect Lysogenic Genomes.

    abstract：:Bacterial CRISPR-Cas systems employ RNA-guided nucleases to destroy phage (viral) DNA. Phages, in turn, have evolved diverse "anti-CRISPR" proteins (Acrs) to counteract acquired immunity. In Listeria monocytogenes, prophages encode two to three distinct anti-Cas9 proteins, with acrIIA1 always present. However, the sig...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2020.04.001

    authors： Osuna BA,Karambelkar S,Mahendra C,Christie KA,Garcia B,Davidson AR,Kleinstiver BP,Kilcher S,Bondy-Denomy J

    更新日期：2020-07-08 00:00:00

  • Durable protection from Herpes Simplex Virus-2 transmission following intravaginal application of siRNAs targeting both a viral and host gene.

    abstract：:A vaginal microbicide should prevent pathogen transmission without disrupting tissue barriers to infection. Ideally, it would not need to be applied immediately before sexual intercourse, when compliance is a problem. Intravaginal administration of small interfering RNA (siRNA) lipoplexes targeting Herpes Simplex Viru...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2008.12.003

    authors： Wu Y,Navarro F,Lal A,Basar E,Pandey RK,Manoharan M,Feng Y,Lee SJ,Lieberman J,Palliser D

    更新日期：2009-01-22 00:00:00

  • Networking at the level of host immunity: immune cell interactions during persistent viral infections.

    abstract：:Persistent viral infections are the result of a series of connected events that culminate in diminished immunity and the inability to eliminate infection. By building our understanding of how distinct components of the immune system function both individually and collectively in productive versus abortive responses, n...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2013.05.014

    authors： Ng CT,Snell LM,Brooks DG,Oldstone MB

    更新日期：2013-06-12 00:00:00

  • The Innate Sense of Bacteriophages.

    abstract：:Perturbation of the gut microbiota is associated with inflammatory bowel disease, obesity, and even cancer. In this issue of Cell Host & Microbe, Gogokhia et al. 2019 sought to kill cancer-causing bacteria with bacteriophages. However, the bacteriophages themselves directly stimulated an immune response, which worsene...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2019.01.020

    authors： Bollyky PL,Secor PR

    更新日期：2019-02-13 00:00:00

  • Mycobacterium tuberculosis Meets the Cytosol: The Role of cGAS in Anti-mycobacterial Immunity.

    abstract：:The intracellular fate of Mycobacterium tuberculosis is a subject of long debate. In this issue of Cell Host & Microbe, three independent studies reveal the detection of cytosolic mycobacterial DNA by the nucleotidyltransferase cGAS, emphasizing the concept of cytosolic access by M. tuberculosis and its role in balanc...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2015.05.017

    authors： Majlessi L,Brosch R

    更新日期：2015-06-10 00:00:00

  • ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.

    abstract：:The Cullin-RING E3 ligase (CRL) family is commonly hijacked by pathogens to redirect the host ubiquitin proteasome machinery to specific targets. During HIV infection, CRL5 is hijacked by HIV Vif to target viral restriction factors of the APOBEC3 family for ubiquitination and degradation. Here, using a quantitative pr...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2019.05.008

    authors： Hüttenhain R,Xu J,Burton LA,Gordon DE,Hultquist JF,Johnson JR,Satkamp L,Hiatt J,Rhee DY,Baek K,Crosby DC,Frankel AD,Marson A,Harper JW,Alpi AF,Schulman BA,Gross JD,Krogan NJ

    更新日期：2019-07-10 00:00:00

  • A Blueprint for HIV Vaccine Discovery.

    abstract：:Despite numerous attempts over many years to develop an HIV vaccine based on classical strategies, none has convincingly succeeded to date. A number of approaches are being pursued in the field, including building upon possible efficacy indicated by the recent RV144 clinical trial, which combined two HIV vaccines. Her...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2012.09.008

    authors： Burton DR,Ahmed R,Barouch DH,Butera ST,Crotty S,Godzik A,Kaufmann DE,McElrath MJ,Nussenzweig MC,Pulendran B,Scanlan CN,Schief WR,Silvestri G,Streeck H,Walker BD,Walker LM,Ward AB,Wilson IA,Wyatt R

    更新日期：2012-10-18 00:00:00

  • Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut.

    abstract：:Probiotics are living microorganisms that are increasingly used as gastrointestinal therapeutics by virtue of their innate or engineered genetic function. Unlike abiotic therapeutics, probiotics can replicate in their intended site, subjecting their genomes and therapeutic properties to natural selection. We exposed t...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2019.02.005

    authors： Crook N,Ferreiro A,Gasparrini AJ,Pesesky MW,Gibson MK,Wang B,Sun X,Condiotte Z,Dobrowolski S,Peterson D,Dantas G

    更新日期：2019-04-10 00:00:00

  • miR-122 stimulates hepatitis C virus RNA synthesis by altering the balance of viral RNAs engaged in replication versus translation.

    abstract：:The liver-specific microRNA, miR-122, stabilizes hepatitis C virus (HCV) RNA genomes by recruiting host argonaute 2 (AGO2) to the 5' end and preventing decay mediated by exonuclease Xrn1. However, HCV replication requires miR-122 in Xrn1-depleted cells, indicating additional functions. We show that miR-122 enhances HC...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2014.12.014

    authors： Masaki T,Arend KC,Li Y,Yamane D,McGivern DR,Kato T,Wakita T,Moorman NJ,Lemon SM

    更新日期：2015-02-11 00:00:00

  • A new antituberculosis drug that selectively kills nonmultiplying Mycobacterium tuberculosis.

    abstract：:An important report by Bryk et al. in this issue of Cell Host & Microbe describes the properties of a rhodanine prodrug active against nonmultiplying Mycobacterium tuberculosis (Mtb). Considering the tolerance of nonreplicating Mtb to most currently available agents, such a drug could be a major addition to our antitu...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2008.02.013

    authors： Mitchison DA

    更新日期：2008-03-13 00:00:00

  • Not Your Typical Anti-CRISPR.

    abstract：:In this issue of Cell Host & Microbe, two papers by Osuna et al. describe the characterization of AcrIIA1, an anti-CRISPR protein distributed widely among Listeria phages. AcrIIA1 functions as an anti-CRISPR and as a dynamic repressor of acr loci, suggesting it may play an important role in lysogeny. ...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2020.06.016

    authors： Johnson WE

    更新日期：2020-07-08 00:00:00

  • Microbial-derived butyrate: an oncometabolite or tumor-suppressive metabolite?

    abstract：:Dietary factors, microbial composition, and metabolism are intimately intertwined into a complex network whose activities influence important intestinal functions. In a recent issue of Cell, Belcheva et al. (2014) show that microbial-derived butyrate promotes proliferation of cancer-initiated intestinal epithelial cel...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2014.07.011

    authors： Bultman SJ,Jobin C

    更新日期：2014-08-13 00:00:00

  • Duffy antigen receptor for chemokines mediates trans-infection of HIV-1 from red blood cells to target cells and affects HIV-AIDS susceptibility.

    abstract：:Duffy antigen receptor for chemokines (DARC) expressed on red blood cells (RBCs) influences plasma levels of HIV-1-suppressive and proinflammatory chemokines such as CCL5/RANTES. DARC is also the RBC receptor for Plasmodium vivax. Africans with DARC -46C/C genotype, which confers a DARC-negative phenotype, are resista...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2008.06.002

    authors： He W,Neil S,Kulkarni H,Wright E,Agan BK,Marconi VC,Dolan MJ,Weiss RA,Ahuja SK

    更新日期：2008-07-17 00:00:00

  • Surviving as a Community: Antibiotic Tolerance and Persistence in Bacterial Biofilms.

    abstract：:Biofilms are surface-associated bacterial communities that play both beneficial and harmful roles in nature, medicine, and industry. Tolerant and persister cells are thought to underlie biofilm-related bacterial recurrence in medical and industrial contexts. Here, we review recent progress aimed at understanding the m...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2019.06.002

    authors： Yan J,Bassler BL

    更新日期：2019-07-10 00:00:00

  • A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle.

    abstract：:A family of apicomplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s) was identified in malaria parasites. This family includes sequence-specific transcription factors that are key regulators of development. However, functions for the majority of ApiAP2 genes remain unknown. Here, a systematic knockou...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2016.12.003

    authors： Modrzynska K,Pfander C,Chappell L,Yu L,Suarez C,Dundas K,Gomes AR,Goulding D,Rayner JC,Choudhary J,Billker O

    更新日期：2017-01-11 00:00:00

  • Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence.

    abstract：:Typhoidal and non-typhoidal Salmonelleae (NTS) cause typhoid fever and gastroenteritis, respectively, in humans. Salmonella typhoid toxin contributes to typhoid disease progression and chronic infection, but little is known about the role of its NTS ortholog. We found that typhoid toxin and its NTS ortholog induce dif...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2020.04.005

    authors： Lee S,Yang YA,Milano SK,Nguyen T,Ahn C,Sim JH,Thompson AJ,Hillpot EC,Yoo G,Paulson JC,Song J

    更新日期：2020-06-10 00:00:00