Prevalence of Chronic Kidney Disease, Thrombotic Cardiovascular Events, and Use of Oral P2Y12 Inhibitors among Veterans.

abstract：BACKGROUND:We determined the familial aggregation of end-stage renal disease (ESRD) in a large, population-based sample of incident ESRD cases to assess the feasibility of developing a targeted screening and prevention program directed at members of families at high risk for kidney disease. METHODS:Between January 1, ...

journal_title：American journal of nephrology

authors： Freedman BI,Volkova NV,Satko SG,Krisher J,Jurkovitz C,Soucie JM,McClellan WM

更新日期：2005-11-01 00:00:00

abstract：:Several medical inventors in Europe and North America brought the artificial kidney (hemodialysis) to practical usefulness in the late 1940s, but there were very few early successes. It was used at first for only desperate cases of acute renal failure. Renal authorities in the 'metabolic' tradition favored newly quant...

journal_title：American journal of nephrology

authors： Peitzman SJ

更新日期：1997-01-01 00:00:00

abstract：:Chronic kidney disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importan...

journal_title：American journal of nephrology

authors： Piccoli GB,Alrukhaimi M,Liu ZH,Zakharova E,Levin A,World Kidney Day Steering Committee.

更新日期：2018-01-01 00:00:00

abstract：:Accelerated atherosclerosis is both a cause and a consequence of chronic renal failure. Vascular smooth muscle cells (VSMCs) are an important component of atherosclerotic plaques, responsible for promoting plaque stability in advanced lesions. In contrast, VSMC apoptosis has been implicated in a number of deleterious ...

journal_title：American journal of nephrology

authors： Clarke M,Bennett M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIMS:There is a critical need for more noninvasive biomarkers to identify nephritis in patients with systemic lupus erythematosus (SLE). Recent studies in a model mouse and an adult SLE patient cohort suggest that anti-basement membrane antibody levels correlate well with lupus activity and kidney injury. Th...

journal_title：American journal of nephrology

authors： Orjuela A,Suwanichkul A,Canter D,Minard CG,Devaraj S,Hicks MJ,Muscal E,Wenderfer SE

更新日期：2015-01-01 00:00:00

abstract：:Fifty-four patients with noninsulin-dependent diabetes mellitus, who had established nephropathy, were examined to evaluate the risk factors for the progression of diabetic nephropathy. Time-averaged values of blood pressure, serum total cholesterol and fasting plasma glucose concentrations, and the degree of proteinu...

journal_title：American journal of nephrology

authors： Yokota C,Kimura G,Inenaga T,Kawano Y,Matsuoka H,Omae T

更新日期：1995-01-01 00:00:00

abstract：:Renal function and life expectancy can be improved by aggressive antihypertensive therapy in severe hypertension. However, most reports of severe hypertension and renal failure concern primary hypertensive states. 3 cases of primary renal disease, 1 glomerular, 1 obstructive and 1 of chronic pyelonephritis, are descri...

journal_title：American journal of nephrology

authors： Friedlaender MM,Rubinger D,Popovtzer MM

更新日期：1982-01-01 00:00:00

abstract：:Obese Zucker rats spontaneously develop lipoprotein abnormalities, proteinuria, mesangial expansion and glomerulosclerosis. Previous studies have implicated these lipoprotein abnormalities in the pathogenesis of the progressive renal injury which these rats develop. The present study was designed to examine the chrono...

journal_title：American journal of nephrology

authors： Kamanna VS,Kirschenbaum MA

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Hemodialysis (HD) patients are more inactive, leading to poor functional capacity and quality of life; this may be reversed with intradialytic exercise training. To systematically evaluate the efficacy and safety of intradialytic exercise for HD patients, we conducted a meta-analysis of the pub...

journal_title：American journal of nephrology

authors： Sheng K,Zhang P,Chen L,Cheng J,Wu C,Chen J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although the effect of exercise on health is well established, nephrologists seldom consider physical activity in the treatment of chronic kidney disease (CKD) or CKD in the presence of diabetes mellitus (DM/CKD). The aim of the present study was to analyze the benefits of leisure-time physical activity...

journal_title：American journal of nephrology

authors： Wang IK,Tsai MK,Liang CC,Yen TH,Huang CC,Wen SF,Wen CP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is a rare renal tubular disorder complicated by progressive renal failure during childhood or adolescence. Recently, causative mutations in the CLDN19 gene have been identified in FHHNC patients presenting with severe ocular involv...

journal_title：American journal of nephrology

authors： Naeem M,Hussain S,Akhtar N

更新日期：2011-01-01 00:00:00

abstract：:In general, nonrheumatic atrial fibrillation is associated with a high risk of stroke. However, its impact on stroke in the setting of chronic hemodialysis treatment is insufficiently addressed in the literature. We assessed the incidence of stroke among 430 chronic hemodialysis patients and the impact of atrial fibri...

journal_title：American journal of nephrology

authors： Wiesholzer M,Harm F,Tomasec G,Barbieri G,Putz D,Balcke P

更新日期：2001-01-01 00:00:00

abstract：:A 50-year-old woman presented with thrombocytopenia, microangiopathic hemolytic anemia, and nephrotic syndrome. Although a high level of circulating immune complexes, mild hypocomplementemia, and the antinuclear antibody also were present, the criteria for collagen disease were not fulfilled. Renal biopsy demonstrated...

journal_title：American journal of nephrology

authors： Kimura M,Fujigaki Y,Ohtake T,Furuya R,Hishida A,Kaneko E

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Serum phosphorus concentrations reflect a dynamic balance between generation, exchanges, and removal. Time-averaged phosphorus concentrations (TAC(phos)) reflect the overall exposure better than single time-point concentrations, especially in dialysis patients treated with an intermittent modality. The prese...

journal_title：American journal of nephrology

authors： Viaene L,Meijers B,Vanrenterghem Y,Evenepoel P

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Intradialytic hypotension is the most common complication of modern day haemodialysis (HD). Convective modalities, including haemodiafiltration (HDF) are reported to result in greater cardiovascular stability compared to standard HD, which has been suggested to be due to improved solute transport betwee...

journal_title：American journal of nephrology

authors： Kumar S,Khosravi M,Massart A,Potluri M,Davenport A

更新日期：2013-01-01 00:00:00

abstract：:Extraskeletal tumoral calcinosis occur in uremic patients with high calcium phosphorus (Ca x P) product and progressive secondary hyperparathyroidism. However, cases are also described in which this association cannot be confirmed. The influence of aluminum, vitamins D and K, alkalosis, magnesium and local lesions is ...

journal_title：American journal of nephrology

authors： Pecovnik-Balon B,Kramberger S

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Data concerning long-term mortality predictors among large, purely diabetic hemodialysis collectives are scarce. METHODS:We used data from a multicenter, prospective, randomized trial among 1,255 hemodialysis patients with type 2 diabetes mellitus (T2DM) and its observational follow-up study. The associatio...

journal_title：American journal of nephrology

authors： Triebswetter S,Gutjahr-Lengsfeld LJ,Schmidt KR,Drechsler C,Wanner C,Krane V

更新日期：2018-01-01 00:00:00

abstract：:This study describes 10 cases of IgM nephropathy in whom the main morphological findings consisted of diffuse mesangial deposition of IgM and varying degrees of mesangial cell proliferation. In addition, focal segmental sclerosis was present in 1 patient and global sclerosis in another. An ill-defined electron-dense d...

journal_title：American journal of nephrology

authors： Kopolovic J,Shvil Y,Pomeranz A,Ron N,Rubinger D,Oren R

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:We hypothesized that the difference between the prescribed end-dialysis body weight, defined end-dialysis over-weight (edOW; kg), and the body weight which is actually attained could impact survival in hemodialysis (HD) patients. The aim of this prospective observational study was to evaluate if edOW could i...

journal_title：American journal of nephrology

authors： Movilli E,Camerini C,Gaggia P,Zubani R,Feller P,Poiatti P,Pola A,Carli O,Cancarini G

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Increased mortality and morbidity are reported in association with high ultrafiltration rate (UFR) and with long dialysis recovery time (DRT). We studied the association between UFR and DRT. METHODS:This is a cross-sectional, observational study was conducted. Patients on thrice-weekly hemodialysis (HD) wit...

journal_title：American journal of nephrology

authors： Hussein WF,Arramreddy R,Sun SJ,Reiterman M,Schiller B

更新日期：2017-01-01 00:00:00

abstract：:Peritoneal sclerosis, a disorder similar to that previously identified in nonuremic patients, is being noted in peritoneal dialysis patients with increasing frequency. The etiology in dialysis patients remains unknown. An association with previous or ongoing peritoneal inflammation or irritation suggests that the inci...

journal_title：American journal of nephrology

authors： Ing TS,Daugirdas JT,Gandhi VC

更新日期：1984-01-01 00:00:00

abstract：:To evaluate the significance of tubulointerstitial lesions in the cortical area of renal biopsy specimens, clinicopathological studies were performed on 101 cases of IgA nephropathy, 31 cases of IgA-negative (non-IgA) proliferative glomerulonephritis and 75 cases of idiopathic membranous glomerulonephritis. The degree...

journal_title：American journal of nephrology

authors： Abe S,Amagasaki Y,Iyori S,Konishi K,Kato E,Sakaguchi H

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:To evaluate the predictive value of dialysate interleukin-6 (IL-6) representing local subclinical intraperitoneal inflammation for the development of peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients. METHODS:Stable prevalent CAPD patients were enrolled in this prospective study. IL-6...

journal_title：American journal of nephrology

authors： Yang X,Tong Y,Yan H,Ni Z,Qian J,Fang W

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:A poor nutritional state is associated with an increased risk of cardiovascular events in end-stage renal disease. It is unclear whether malnutrition itself can induce cardiovascular disease (CVD). We examined the impact of nutritional status on patients' arterial stiffness in peritoneal dialysis (PD) patien...

journal_title：American journal of nephrology

authors： Tang W,Cheng LT,Lu XH,Wang T

更新日期：2009-01-01 00:00:00

abstract：:The purpose of the present investigation was to determine whether dexamethasone, an agent known to preserve the blood-brain barrier, and colchicine, an agent that impairs mobilization of macrophages, can prevent demyelinating lesions associated with rapid correction of hyponatremia in the experimental animal. Hyponatr...

journal_title：American journal of nephrology

authors： Oh MS,Choi KC,Uribarri J,Sher J,Rao C,Carroll HJ

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cisplatin (CIS) induces nephrotoxicity partly through renal vasoconstriction and decreased glomerular filtration effects thought to involve adenosine acting on adenosine A(1) receptors (A1Rs). We studied the effect of the orally active, A1R antagonist tonapofylline (BG9928) on biochemical measures of re...

journal_title：American journal of nephrology

authors： Gill A,Wortham K,Costa D,Davis W,Ticho B,Whalley E

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Renal insufficiency is a well-described risk factor for perioperative morbidity and shortened survival after major vascular procedures. Due to the potential inaccuracy of serum creatinine levels alone in measuring kidney function, our aim was to determine whether estimated creatinine clearance more consisten...

journal_title：American journal of nephrology

authors： Maithel SK,Pomposelli FB,Williams M,Sheahan MG,Scovell SD,Campbell DR,LoGerfo FW,Hamdan AD

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:2009 influenza A has spread globally. Respiratory complications and renal failure have been the leading causes for hospitalization and critical illness. We describe the risk factors and complications of acute kidney injury (AKI) in patients with influenza A. METHODS:Observational study of adult patients tes...

journal_title：American journal of nephrology

authors： Demirjian SG,Raina R,Bhimraj A,Navaneethan SD,Gordon SM,Schreiber MJ Jr,Guzman JA

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) impairs intestinal barrier function which by allowing influx of noxious products causes systemic inflammation. We have recently shown that intestinal barrier dysfunction in CKD is due to degradation of epithelial tight junction (TJ) which is, in part, mediated by influx of urea a...

journal_title：American journal of nephrology

authors： Vaziri ND,Yuan J,Khazaeli M,Masuda Y,Ichii H,Liu S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Oxidative stress and inflammation are known to play central roles in the development of diabetic nephropathy (DN). Febuxostat is a novel non-purine xanthine oxidase (XO)-specific inhibitor developed to treat hyperuricemia. In this study, we investigated whether febuxostat could ameliorate DN via renoprotecti...

journal_title：American journal of nephrology

authors： Lee HJ,Jeong KH,Kim YG,Moon JY,Lee SH,Ihm CG,Sung JY,Lee TW

更新日期：2014-01-01 00:00:00