Mutations within A 35 amino acid region of P6 influence self-association, inclusion body formation, and Caulimovirus infectivity.

abstract：:We describe studies of woodchuck hepatitis virus nucleic acids in liver and other tissues of chronically infected woodchucks, using Southern and Northern blot hybridization techniques. Single-stranded and covalently closed circular replicative DNA molecules were distinguished from partly double-stranded virus genomes....

journal_title：Virology

authors： Ogston CW,Schechter EM,Humes CA,Pranikoff MB

更新日期：1989-03-01 00:00:00

abstract：:Recombinant baculoviruses containing the coding sequences of the viral structural proteins, i.e., the capsid (C) protein, the precursor to premembrane (preM) protein, and the envelope (E) protein, as well as a nonstructural protein, NS1, of Japanese encephalitis virus (JEV) were constructed. Infection of Spodoptera fr...

journal_title：Virology

authors： Matsuura Y,Miyamoto M,Sato T,Morita C,Yasui K

更新日期：1989-12-01 00:00:00

abstract：:The DNAs from the granulosis viruses of Plodia interpunctella and Pieris rapae were clearly distinguishable based on restriction endonuclease fragment patterns. By sizing single- and double-digestion products approximate molecular weights of 72 x 10(2) and 75 x 10(6), respectively, were estimated for the viral genomes...

journal_title：Virology

authors： Tweeten KA,Bulla LA Jr,Consigli RA

更新日期：1980-07-30 00:00:00

abstract：:The avian hematopoietic system has long been an invaluable model to study the mechanisms of cell growth and differentiation. We have developed six MAbs against either chicken embryonic hematopoietic precursor cells or retrovirus-transformed cells. MAbs Mo1, Mo2, and Mo3 recognized transformation-associated markers exp...

journal_title：Virology

authors： Liu JL,Klein PA,Moscovici MG,Moscovici C

更新日期：1992-08-01 00:00:00

abstract：:While several studies have shown a role for autophagy in the replication of dengue virus (DENV), these studies have been performed in directly infected cells. However, in severe cases of DENV infection the critical cell in the disease is believed to be monocytes which are poorly infected directly, but are highly susce...

journal_title：Virology

authors： Panyasrivanit M,Greenwood MP,Murphy D,Isidoro C,Auewarakul P,Smith DR

更新日期：2011-09-15 00:00:00

abstract：:Feline calicivirus depends on host-cell proteins for its replication. We previously showed that knockdown of nucleolin (NCL), a phosphoprotein involved in ribosome biogenesis, resulted in the reduction of FCV protein synthesis and virus yield. Here, we found that NCL may not be involved in FCV binding and entry into c...

journal_title：Virology

authors： Hernández BA,Sandoval-Jaime C,Sosnovtsev SV,Green KY,Gutiérrez-Escolano AL

更新日期：2016-02-01 00:00:00

abstract：:New BVDV strains associated with very high mortalities, which killed about 25% of the veal calves in Quebec in 1993, have been isolated. In this study, characterization of the last two-thirds of the 5' untranslated region (5'UTR) of their genome and virus neutralization experiments with polyvalent antisera raised in d...

journal_title：Virology

authors： Pellerin C,van den Hurk J,Lecomte J,Tijssen P

更新日期：1994-09-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) Gag proteins are assembled into virus particles and then cleaved by the virion-associated HIV protease. Concomitant with Gag processing, doughnut-like HIV particles (the immature form) are converted to particles containing condensed cores (the mature form). Here we describe the in vi...

journal_title：Virology

authors： Morikawa Y,Shibuya M,Goto T,Sano K

更新日期：2000-07-05 00:00:00

abstract：:Resistance to lethal encephalitis in mice infected with HSV-1 via the oral mucosa is mouse strain dependent. In susceptible BALB/c, HSV-1 spreads throughout the CNS but in resistant BL/6 mice, virus is restricted to the brainstem. To examine the contribution of cellular immunity in restricting viral spread, we used a ...

journal_title：Virology

authors： Kastrukoff LF,Lau AS,Takei F,Smyth MJ,Jones CM,Clarke SR,Carbone FR

更新日期：2010-05-10 00:00:00

abstract：:We have investigated the effect of a monoclonal antibody on influenza virus release and the cell surface expression of M2, comparing virus strains which were observed previously to be sensitive (A/Udorn) or resistant (A/WSN and A/Udorn variants) to growth inhibition by M2 antibody 14C2. Incubation of A/Udorn virus-inf...

journal_title：Virology

authors： Hughey PG,Roberts PC,Holsinger LJ,Zebedee SL,Lamb RA,Compans RW

更新日期：1995-10-01 00:00:00

abstract：:Astrocytes protect neurons but also evoke a proinflammatory response to injury and viral infections including HIV. We investigated the mechanism of HIV-1 infection in primary astrocytes, which showed minimal but productive viral infection independent of CXCR4. As with ectopic-CD4-expressing astrocytes, lysosomotropic ...

journal_title：Virology

authors： Chauhan A,Mehla R,Vijayakumar TS,Handy I

更新日期：2014-05-01 00:00:00

abstract：:The behavior of two genetically different molecular clones of visna virus KV1772-kv72/67 and LV1-1KS1 was compared in vivo and in vitro. On intracerebral inoculation, clone KV1772-kv72/67 induced a similar response in five sheep as has already been reported with neurovirulent derivates of visna virus. Virus was freque...

journal_title：Virology

authors： Torsteinsdóttir S,Agnarsdóttir G,Matthíasdóttir S,Rafnar B,Andrésdóttir V,Andrésson OS,Staskus K,Pétursson G,Pálsson PA,Georgsson G

更新日期：1997-03-17 00:00:00

abstract：:The MC80R gene of molluscum contagiosum virus (MCV) type 1 encodes a major histocompatibility complex (MHC) class I homolog that lacks several amino-acid residues critical for peptide binding by MHC molecules, contains an unusually long N-terminal hydrophobic domain possibly derived by triplication of a signal peptide...

journal_title：Virology

authors： Senkevich TG,Moss B

更新日期：1998-10-25 00:00:00

abstract：:Equid herpesvirus-1 (EHV-1) outbreaks continue despite widely used vaccination. We demonstrated previously that an ORF1/ORF71 gene deletion mutant of the EHV-1 strain Ab4 (Ab4ΔORF1/71) is less virulent than its parent Ab4 virus. Here, we describe the Ab4 challenge infection evaluating protection induced by the Ab4ΔORF...

journal_title：Virology

authors： Perkins G,Babasyan S,Stout AE,Freer H,Rollins A,Wimer CL,Wagner B

更新日期：2019-05-01 00:00:00

abstract：:Two major infectious forms of vaccinia virus (VACV) have been described: the intracellular mature virion (IMV), and the extracellular enveloped virion (EEV). Due to their stability in the environment, IMVs play a predominant role in host-to-host transmission, whereas EEVs play an important role in dissemination within...

journal_title：Virology

authors： Hooper JW,Custer DM,Thompson E

更新日期：2003-02-01 00:00:00

abstract：:H5 and H7 avian influenza viruses can become highly pathogenic in chickens after interspecies transmission. These viruses have transmitted directly to humans from birds in Eurasia and Africa (H5N1), the Netherlands (H7N7), and Canada (H7N3). Here we report antigenic, sequence, and phylogenetic analyses of H7N3 viruses...

journal_title：Virology

authors： Aamir UB,Naeem K,Ahmed Z,Obert CA,Franks J,Krauss S,Seiler P,Webster RG

更新日期：2009-08-01 00:00:00

abstract：:Viral infections of the central nervous system and immune responses to these infections cause a variety of neurological diseases. Infection of weanling mice with Sindbis virus causes acute nonfatal encephalomyelitis followed by clearance of infectious virus, but persistence of viral RNA. Infection with a neuroadapted ...

journal_title：Virology

authors： Kimura T,Griffin DE

更新日期：2003-06-20 00:00:00

abstract：:Virus infection may contribute to asthma pathogenesis. In turn, a Th2-polarized pulmonary environment may increase host susceptibility to infection. We used a cockroach antigen (CRA) model of allergic airway disease to test the hypothesis that Th2 cytokine overproduction increases susceptibility to mouse adenovirus ty...

journal_title：Virology

authors： Anderson VE,Nguyen Y,Weinberg JB

更新日期：2009-08-15 00:00:00

abstract：:In an attempt to develop an in vitro human cytomegalovirus (HCMV) latency model system, the growth characteristics of HCMV in a human thyroid papillary carcinoma cell line (TPC-1) were examined. When TPC-1 cultures preheated at 40.5 degrees for 48 hr were infected with HCMV and incubated at a supraoptimal temperature ...

journal_title：Virology

authors： Tanaka J,Ogura T,Sato H,Hatano M

更新日期：1987-11-01 00:00:00

abstract：:The atomic structure of the DNA-containing T = 1 particle of the parvovirus minute virus of mice (MVM) reveals cylindrical projections at each fivefold symmetry axis, each containing an 8 Angstrom pore through which runs 10 amino acids of a single VP2 N-terminus. The tightest constriction of this pore is formed at its...

journal_title：Virology

authors： Farr GA,Tattersall P

更新日期：2004-06-01 00:00:00

abstract：:The alphaherpesviruses establish latent infections in sensory neuronal cells, during which a number of latency-associated RNA transcripts (LATs) are produced. The reasons for the production of the LATs, however, and the mechanism by which the LAT region of the genome remains active during latency are unknown. Here we ...

journal_title：Virology

authors： Coffin RS,Howard MK,Latchman DS

更新日期：1995-06-01 00:00:00

abstract：:Two temperature-sensitive mutants of cowpea mosaic virus have been isolated following nitrous acid mutagenesis. One mutant, 8-14, was shown to have a temperature-sensitive defect in the B component RNA. The location of the temperature-sensitive defect of the other mutant, 8-10, was not unambiguously determined. No vir...

journal_title：Virology

authors： Evans D

更新日期：1985-03-01 00:00:00

abstract：:Rotavirus infection was studied in adult nude mice (BALB/c background), alpha beta or gamma delta and alpha beta/gamma delta T cell receptor (TCR) knockout (-/-) mice (C57BL/6 and C57BL/6 x 129 backgrounds), and SCID mice (C57BL/6 background). The gamma delta TCR -/- mice cleared infection just like control mice. All ...

journal_title：Virology

authors： Franco MA,Greenberg HB

更新日期：1997-11-24 00:00:00

abstract：:To determine if West Nile virus (WNV) infection of insect cells induces a protective RNAi response, Drosophila melanogaster S2 and Aedes albopictus C6/36 cells were infected with WNV, and the production of WNV-homologous small RNAs was assayed as an indicator of RNAi induction. A distinct population of approximately 2...

journal_title：Virology

authors： Chotkowski HL,Ciota AT,Jia Y,Puig-Basagoiti F,Kramer LD,Shi PY,Glaser RL

更新日期：2008-07-20 00:00:00

abstract：:The Fgf-3 protooncogene (previously called int-2) is a target of proviral insertion mutations in mammary tumors induced by the mouse mammary tumor virus (MMTV). These insertion mutations result in the transcriptional activation of Fgf-3, which is not normally expressed in the adult mammary gland. Previous mapping stud...

journal_title：Virology

authors： Morris DW,Dutra JC

更新日期：1997-11-10 00:00:00

abstract：:The bipartite genomic RNAs of red clover necrotic mosaic virus (RCNMV) lack a 5' cap and a 3' poly(A) tail. RNA1 encodes viral replication proteins, and RNA2 encodes a movement protein (MP). These proteins are translated in a cap-independent manner. We previously identified two cis-acting RNA elements that cooperative...

journal_title：Virology

authors： Tajima Y,Iwakawa HO,Hyodo K,Kaido M,Mise K,Okuno T

更新日期：2017-09-01 00:00:00

abstract：:Section of the sciatic nerve during the period of herpes simplex virus (HSV) latent infection was performed to evaluate residual latency in mouse dorsal root ganglion. In control mice without sciatic neurectomy, latency was present in 90-100%, while in those which underwent a neurectomy procedure, latent infection was...

journal_title：Virology

authors： Tenser RB,Edris WA,Hay KA

更新日期：1988-11-01 00:00:00

abstract：:Retroviruses can be grouped by viral interference measurements into classes which use common cell surface receptors. We previously tested a large number of isolates of mink cell focus-inducing (MCF) murine leukemia viruses (MuLVs), and reported that all of them share a distinct receptor on NIH/3T3 cells (A. Rein, Viro...

journal_title：Virology

authors： Rein A,Schultz A

更新日期：1984-07-15 00:00:00

abstract：:The coding region of segment 4 of Thogoto (THO) virus, a tick-borne member of the Orthomyxoviridae, was expressed in a baculovirus system under the control of the polyhedrin promoter. This construct expressed authentic envelope glycoprotein as determined by size and antigenic reactivity with a panel of monoclonal anti...

journal_title：Virology

authors： Jones LD,Morse MA,Marriott AC,Nuttall PA

更新日期：1995-10-20 00:00:00

abstract：:A novel virus isolated from the feather follicles of cockatoos diagnosed as having psittacine beak and feather disease was characterized by electron microscopy, nucleic acid content, and polypeptide composition. Purified virions displayed an icosahedral symmetry, were nonenveloped, and had a mean diameter of 14 to 16 ...

journal_title：Virology

authors： Ritchie BW,Niagro FD,Lukert PD,Steffens WL 3rd,Latimer KS

更新日期：1989-07-01 00:00:00