Changes of myocardial functions in acute hepatic porphyrias. Role of heme arginate administration.

abstract：:Transvaginal ultrasonic monitoring of the lower uterine segment was performed in 15 pregnancies in which the mother had previously had three or more caesarean sections. The typical findings were thinning of the myometrium, asymmetric isthmal structures and ventral ballooning of the isthmus. An image of the other of th...

journal_title：Annals of medicine

authors： Kirkinen P

更新日期：1990-04-01 00:00:00

abstract：INTRODUCTION:We studied prevalence of hypovitaminosis D, its determinants, and whether achievement of recommended dietary vitamin D intake (10 μg/d) is associated with absence of hypovitaminosis D in adults. METHODS:The study is part of the Cardiovascular Risk in Young Finns Study. We collected serum samples of 25-hyd...

journal_title：Annals of medicine

authors： Voipio AJ,Pahkala KA,Viikari JS,Mikkilä V,Magnussen CG,Hutri-Kähönen N,Kähönen M,Lehtimäki T,Männistö S,Loo BM,Jula A,Marniemi J,Juonala M,Raitakari OT

更新日期：2015-05-01 00:00:00

abstract：:The purpose of this study was to test the applicability of exercise echocardiography in the diagnosis of coronary artery disease. The results were compared to findings of coronary angiography. 118 patients, 100 males and 18 females, who were all referred to coronary angiography for suspected ischaemic heart disease, u...

journal_title：Annals of medicine

authors： Luotolahti M,Saraste M,Hartiala J

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Several clinical studies have suggested possible increase in cardiovascular risk during and in the first weeks after an acute inflammatory disease. Using influenza vaccine as inflammatory stimulus, we investigated whether arterial endothelial dysfunction could persist beyond the inflammatory state, and wheth...

journal_title：Annals of medicine

authors： Liuba P,Aburawi EH,Pesonen E,Andersson S,Truedsson L,Ylä-Herttuala S,Holmberg L

更新日期：2007-01-01 00:00:00

abstract：:Steroids diffuse through polysiloxone at a constant rate, and steroids placed in the vagina rapidly pass through the vaginal epithelium into the circulation. Combining these principles led to the development of contraceptive vaginal rings (CVR) consisting of various progestins, with and without oestrogen, placed in fl...

journal_title：Annals of medicine

authors： Mishell DR Jr

更新日期：1993-04-01 00:00:00

abstract：:When the optimal chemotherapy regimen for advanced ovarian cancer is discussed the following should be considered: the type and number of drugs, the dose of individual drugs and the number of cycles. Optimal chemotherapy should include a platinum compound, because platinum-based chemotherapy yields a superior response...

journal_title：Annals of medicine

authors： Bertelsen K

更新日期：1995-02-01 00:00:00

abstract：:In order to assess the effectiveness of lifestyle interventions in reducing cardiovascular disease risk factors, morbidity and mortality among working-age adults, we undertook a systematic review of randomized controlled trials of various lifestyle interventions (diet, exercise, smoking cessation, alcohol intake reduc...

journal_title：Annals of medicine

authors： Ketola E,Sipilä R,Mäkelä M

更新日期：2000-05-01 00:00:00

abstract：:The understanding and treatment of schizophrenia have been greatly hampered by uncertainty about etiological factors and controversy about diagnostic boundaries. Adoption studies have helped clarify both of these problems. First, the adoptees study method, the index offspring of adopting-away schizophrenic biological ...

journal_title：Annals of medicine

authors： Tienari PJ,Wynne LC

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Heart rate (HR), heart rate variability (HRV), and inflammation are all associated with cardiovascular morbidity and mortality. The aim of this study was to assess potential interrelationships between these parameters in a young and healthy population. METHODS:Healthy individuals aged 25-41 years were inclu...

journal_title：Annals of medicine

authors： Aeschbacher S,Schoen T,Dörig L,Kreuzmann R,Neuhauser C,Schmidt-Trucksäss A,Probst-Hensch NM,Risch M,Risch L,Conen D

更新日期：2017-02-01 00:00:00

abstract：:During recent decades an increasing number of case reports have pointed at a relation between atrophic gastritis type A and gastric carcinoid. This relation has now been quantitatively documented in endoscopic screening studies. Among patients with pernicious anaemia the prevalence of gastric carcinoid was 2-9%. Many ...

journal_title：Annals of medicine

authors： Borch K

更新日期：1989-08-01 00:00:00

abstract：INTRODUCTION:The objective of the present study was to examine the association between low-grade albuminuria and hearing impairment in the non-diabetic population. MATERIALS AND METHODS:Data from the Korean National Health and Nutrition Examination Survey 2011-2013 were used in the analyses. Participants were excluded...

journal_title：Annals of medicine

authors： Kang SH,Jung DJ,Choi EW,Park JW,Cho KH,Yoon KW,Do JY

更新日期：2015-01-01 00:00:00

abstract：:Several lines of evidence suggest that abnormal brain serotonin metabolism may occur in early onset, type 2 alcoholism in men. Low cerebrospinal fluid 5-hydroxy-indoleacetic acid concentration has been found to be associated with a history of paternal alcoholism, and abnormal oral glucose tolerance tests (tendency to ...

journal_title：Annals of medicine

authors： Virkkunen M,Linnoila M

更新日期：1990-01-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs (NSAIDs) and specific inhibitors of cyclooxygenase (COX)-2, are therapeutic groups widely used for the treatment of pain, inflammation and fever. There is growing experimental and clinical evidence indicating NSAIDs and COX-2 inhibitors also have anti-cancer activity. Epidemiologi...

journal_title：Annals of medicine

authors： Rüegg C,Zaric J,Stupp R

更新日期：2003-01-01 00:00:00

abstract：:Abstract The limits of traditional anticoagulants, such as heparin and warfarin, have prompted the search for new agents for prophylaxis and treatment of arterial and venous thromboembolism, including factor Xa and thrombin inhibitors. These agents can be given orally, and their most significant advantage is that no l...

journal_title：Annals of medicine

authors： Mannucci PM,Franchini M

更新日期：2011-03-01 00:00:00

abstract：:A comprehensive study of coronary heart disease (CHD) risk factors and their determinants in children and adolescents in Finland was initiated in the late 1970's. The main cross-sectional study was undertaken in 1980, with 3596 subjects aged from 3 to 18 years participating. The first follow-up study was carried out i...

journal_title：Annals of medicine

authors： Akerblom HK,Viikari J,Räsänen L,Kuusela V,Uhari M,Lautala P

更新日期：1989-06-01 00:00:00

abstract：:Atrial fibrillation is a common cardiac arrhythmia with rapid and irregular atrial activity. Instead of uniformly contracting as one chamber, the atrial compartment fibrillates. Several studies have demonstrated that this arrhythmia contributes substantially to cardiac morbidity and mortality. The purpose of this revi...

journal_title：Annals of medicine

authors： Miyazaki S,Shah AJ,Scherr D,Haïssaguerre M

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Obesity has reached epidemic proportions worldwide. Maternal obesity has consequences for the offspring's later health. Only few studies have focused upon the long-term consequences of maternal obesity on the offspring's later health. METHODS:A total of 13,345 men and women born in Helsinki during 1934-44...

journal_title：Annals of medicine

authors： Eriksson JG,Sandboge S,Salonen MK,Kajantie E,Osmond C

更新日期：2014-09-01 00:00:00

abstract：:Vaccines are considered to be one of the greatest public health achievements of the last century. Depending on the biology of the infection, the disease to be prevented, and the targeted population, a vaccine may require the induction of different adaptive immune mechanisms to be effective. Understanding the basic con...

journal_title：Annals of medicine

authors： Vetter V,Denizer G,Friedland LR,Krishnan J,Shapiro M

更新日期：2018-03-01 00:00:00

abstract：:Immunocytochemical studies using antibodies to cytoskeletal proteins have provided conflicting data on the components of paired helical filaments (PHF), due solely to immunological cross-reactivities. To avoid such ambiguity, we developed a protein chemical approach to the identification of the PHF components. After t...

journal_title：Annals of medicine

authors： Ihara Y,Kondo J

更新日期：1989-01-01 00:00:00

abstract：:Despite striking extensions of lifespan, leading causes of death in most countries now constitute chronic, degenerative diseases which outpace the capacity of health systems. Cardiovascular disease is the most common cause of death in both developed and undeveloped countries. In America, nearly half of the adult popul...

journal_title：Annals of medicine

authors： Kones R,Rumana U

更新日期：2017-05-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic interstitial pneumonia. The disease, which occurs primarily in middle-aged and older adults, is thought to arise following an aberrant reparative response to alveolar epithelial cell injury characterized by secretion of excessive amou...

journal_title：Annals of medicine

authors： Spagnolo P,Sverzellati N,Rossi G,Cavazza A,Tzouvelekis A,Crestani B,Vancheri C

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Teriparatide is a potent anabolic agent for severe osteoporosis. OBJECTIVES:A primary objective of this retrospective study was to define the efficacy of teriparatide in terms of bone mineral density (BMD) changes and relief of back pain in clinical practice. METHODS:The patient population comprises 119 os...

journal_title：Annals of medicine

authors： Koski AM,Löyttyniemi E,Väänänen H,Laine H,Niskanen L,Nevalainen PI,Korpi-Hyövälti E,Välimäki MJ

更新日期：2013-05-01 00:00:00

abstract：:Susceptibility to insulin-dependent diabetes mellitus (IDDM) correlates with the absence of aspartic acid in position 57 of the DQB1 and/or the presence of arginine in position 52 of the DQA1. It has been postulated that transcomplementation between the DQ alpha and beta chains of the two haplotypes could create new m...

journal_title：Annals of medicine

authors： Tuomilehto-Wolf E,Tuomilehto J,Hitman GA

更新日期：1992-12-01 00:00:00

abstract：:Nitric oxide (NO), derived from the vascular endothelium and other cells of the cardiovascular system, has important roles in physiological regulation of blood flow and may have pathophysiological functions in cardiovascular disease. The mechanisms involved in NO-induced vasodilatation and cytotoxicity are briefly rev...

journal_title：Annals of medicine

authors： Dusting GJ,Macdonald PS

更新日期：1995-06-01 00:00:00

abstract：:Recent results from controlled trials of adjuvant tamoxifen and oophorectomy in early breast cancer are reviewed. The results of the statistical overview performed by the Early Breast Cancer Trialists Collaborative Group are summarised, and some important questions left open by this overview are discussed. These inclu...

journal_title：Annals of medicine

authors： Blomqvist CP,Elomaa I,Rissanen P

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Several studies have suggested that the occurrence of severe hypoglycemia during sleep may be more dangerous for cardiac arrhythmia than that in the day-time. METHODS:We performed a retrospective study between January 2006 and March 2012 to assess electrocardiograms during severe hypoglycemia in patients wi...

journal_title：Annals of medicine

authors： Tsujimoto T,Yamamoto-Honda R,Kajio H,Kishimoto M,Noto H,Hachiya R,Kimura A,Kakei M,Noda M

更新日期：2015-05-01 00:00:00

abstract：AIMS:This investigation was designed to explore the role of IL-1RN genotype in unexplained infant deaths (including sudden infant death syndrome (SIDS)), non-infectious infant deaths, and infectious infant deaths, and to investigate whether IL-1RN genotype is related to the finding of organisms in normally sterile site...

journal_title：Annals of medicine

authors： Highet AR,Berry AM,Goldwater PN

更新日期：2010-01-01 00:00:00

abstract：:Visceral obesity is associated with metabolic abnormalities that increase the risk of type 2 diabetes and coronary heart disease. Obese patients with a substantial accumulation of visceral adipose tissue are characterized by higher insulinaemic and glycaemic responses during an oral glucose challenge as well as by a d...

journal_title：Annals of medicine

authors： Després JP

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Female sex, old age, and time to cardioversion increase the risk of thromboembolic complications (TEC) after cardioversion of atrial fibrillation (AF) < 48 h. The interaction of these variables is not known. We investigated the interaction of sex, age, and time to electrical cardioversion (ECV) on TEC in ant...

journal_title：Annals of medicine

authors： Bah A,Nuotio I,Grönberg T,Ylitalo A,Airaksinen KE,Hartikainen JE

更新日期：2017-05-01 00:00:00

abstract：:Obesity in males is accompanied by a significant decrease in testosterone levels. This decrease is essentially a consequence of the decrease of the sex hormone binding hormone (SHBG) binding capacity, itself probably the consequence of the increased insulin levels. In moderate obesity, free testosterone levels are nor...

journal_title：Annals of medicine

authors： Vermeulen A

更新日期：1996-02-01 00:00:00