当前位置： SCI文献检索 > PLASTIC AND RECONSTRUCTIVE SURGERY期刊下所有文献 > Cost analysis of conventional face reconstruction versus face transplantation for large tissue defects.

Cost analysis of conventional face reconstruction versus face transplantation for large tissue defects.

Abstract：

BACKGROUND:Large facial tissue defects are traditionally treated with staged conventional reconstruction. Facial allograft transplantation has emerged as a treatment modality. Facial allografts are procured from a dead donor and transplanted to the recipient. Recipients are then subjected to lifelong global immunosuppression to prevent immunologic rejection. This study analyzes the cost of facial allograft transplantation in comparison with conventional reconstruction. METHODS:Hospital billing records from facial allograft transplantation (2009 to 2011) and conventional reconstruction (2000 to 2010) patients were compiled. Comparative 1-year costs were calculated, segregated by physician, hospital, and hospital's department costs. Because most conventional reconstruction patients had smaller facial deficits than their facial allograft transplantation counterparts, regression models were used to estimate costs of conventional reconstruction for full facial defects, mirroring the facial transplantation cohort. All costs were adjusted using the medical consumer price index. RESULTS:One-year costs for facial allograft transplantation were significantly higher than those for conventional reconstruction (mean/median, $337,360/$313,068 versus $70,230/$64,451, respectively). One-year costs for a hypothetical full-face conventional reconstruction were $184,061 (95 percent CI, $89,358 to $278,763). The per-patient cost in a hypothetical cohort of conventional reconstruction patients with deficits identical to four facial allograft transplantation recipients was $155,475 (95 percent CI, $69,021 to $241,929). CONCLUSIONS:Initial cost comparison portrays facial allograft transplantation as significantly more costly than conventional reconstruction. However, after adjustments for case severity, the cost profiles are similar. Gains in efficiency and experience are expected to lower costs. Additional unmeasured benefits may also positively influence the cost-to-benefit ratio of facial allograft transplantation.

journal_name

Plast Reconstr Surg

journal_title

Plastic and reconstructive surgery

authors

Nguyen LL,Naunheim MR,Hevelone ND,Diaz-Siso JR,Hogan JP,Bueno EM,Caterson EJ,Pomahac B

doi

10.1097/PRS.0000000000000799

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

260-267

issue

eissn

0032-1052

issn

1529-4242

pii

00006534-201501000-00047

journal_volume

135

pub_type

杂志文章

在线工具

Cost analysis of conventional face reconstruction versus face transplantation for large tissue defects.