Abstract:
:Studies of 23 pediatric patients with pachygyriclike changes (PLCs) examined with computed tomography (CT) and magnetic resonance (MR) imaging were reviewed to determine topographic patterns and correlate them with various clinical syndromes and degrees of neurologic impairment. Three types of topographic distributions were identified: unilateral, diffuse, and bilateral nondiffuse (of which eight of 10 showed frontotemporal predominance). PLCs were an isolated finding in seven patients, were associated with various congenital syndromes in nine patients, and were associated with congenital infection in seven patients, six of whom showed marked white matter abnormalities. Although most patients had severe developmental delay, three with nondiffuse PLCs had less severe impairment, permitting less required care.
journal_name
Radiologyjournal_title
Radiologyauthors
Titelbaum DS,Hayward JC,Zimmerman RAdoi
10.1148/radiology.173.3.2554360subject
Has Abstractpub_date
1989-12-01 00:00:00pages
663-7issue
3eissn
0033-8419issn
1527-1315journal_volume
173pub_type
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