Abstract：
BACKGROUND:Understanding actions based on either language or observation of gestures is presumed to involve the motor system, and reflect the engagement of an embodied conceptual network. The role of the left inferior frontal gyrus (IFG) in language tasks is well established, but the role of the right hemisphere is unclear with some imaging evidence suggesting right IFG activation when gestures mismatch speech. OBJECTIVE:Using transcranial direct current stimulation (tDCS), we explored the hemispheric asymmetries in the assumed cognitive embodiment required for gestural-verbal integration. METHODS:Symbolic gestures served as primes for verbal targets. Primes were clips of symbolic gestures taken from a rich set of emblems and pantomimes. Participants responded by performing a semantic relatedness-judgment under 3 stimulation conditions - anodal tDCS (atDCS) over the left IFG, atDCS over the right IFG, and sham. There was also a non-semantic control task of attentional load. RESULTS:AtDCS of the right IFG generated faster responses to symbolic gestures than atDCS over the left IFG or sham stimulation. For the attentional load task, no differences were observed across the three stimulation conditions. These results support a right-lateralization bias of the human mirror neuron system in processing gestural-verbal stimuli. CONCLUSION:Gesture comprehension may be enhanced by improved gesture and language integration.
journal_name
Brain Stimuljournal_title
Brain stimulationauthors
Cohen-Maximov T,Avirame K,Flöel A,Lavidor Mdoi
10.1016/j.brs.2014.12.001subject
Has Abstractpub_date
2015-05-01 00:00:00pages
493-8issue
3eissn
1935-861Xissn
1876-4754pii
S1935-861X(14)00401-Xjournal_volume
8pub_type
杂志文章abstract：BACKGROUND:Recent evidence suggests that transcranial direct current stimulation (tDCS) may interact with the dopaminergic system to affect cognitive flexibility. Objective/hypotheses: We examined whether putative reduction of dopamine levels through the acute phenylalanine/tyrosine depletion (APTD) procedure and excit...
journal_title：Brain stimulation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brs.2019.08.016
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:The efficacy of transcranial magnetic stimulation (TMS) in the treatment of major depression has already been shown. Novel TMS coils allowing stimulation of deeper brain regions have recently been developed and studied. OBJECTIVE:Our study is aimed at exploring the possible efficacy of deep TMS in patients ...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2009.12.001
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Theta burst stimulation (TBS) is a pattern of repetitive transcranial magnetic stimulation that has been demonstrated to facilitate or suppress human corticospinal excitability when applied intermittently (iTBS) or continuously (cTBS), respectively. While the fundamental pattern of TBS, consisting of bursts ...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2013.12.007
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Many individuals with language learning impairments exhibit temporal processing deficits and degraded neural responses to speech sounds. Auditory training can improve both the neural and behavioral deficits, though significant deficits remain. Recent evidence suggests that vagus nerve stimulation (VNS) paire...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2017.01.007
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Transcutaneous vagus nerve stimulation (tVNS) is a new, non-invasive technique being investigated as an intervention for a variety of clinical disorders, including epilepsy and depression. It is thought to exert its therapeutic effect by increasing central norepinephrine (NE) activity, but the evidence suppo...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2018.12.224
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Deep brain stimulation (DBS) has been used for neuropsychiatric disorders in clinical and research settings for almost 50 years now. Recent evidence demonstrates some efficacy in treating obsessive-compulsive disorder and major depression in patients refractory to other treatment modalities beyond single cas...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2010.03.002
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) has shown significant efficiency in the treatment of several psychiatric disorders. In depressive disorders, the dorsolateral prefrontal cortex (DLPFC) is the main target for rTMS, but the effects of this stimulation on cognitive functions and their neural ...
journal_title：Brain stimulation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brs.2012.10.009
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:Vagus nerve stimulation (VNS) paired with forelimb training drives robust, specific reorganization of movement representations in the motor cortex. The mechanisms that underlie VNS-dependent enhancement of map plasticity are largely unknown. The cholinergic nucleus basalis (NB) is a critical substrate in cor...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2015.12.007
更新日期：2016-03-01 00:00:00
abstract：:After acute stroke several changes in cortical excitability occur involving affected (AH) and unaffected hemisphere (UH) but whether they contribute to motor recovery is still controversial. We performed transcranial magnetic stimulation mapping of several upper limb muscles over the two hemispheres in thirteen patien...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2012.06.003
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:Vagus nerve stimulation (VNS) significantly reduces infarct volume in rat models of cerebral ischemia, but the mechanism of this protective effect remains open. HYPOTHESIS:This study tested the hypothesis that non-invasive VNS (nVNS), during transient middle cerebral artery occlusion (MCAO), protects the bl...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2018.01.034
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Pairing sensory or motor events with vagus nerve stimulation (VNS) can reorganize sensory or motor cortex. Repeatedly pairing a tone with a brief period of VNS increases the proportion of primary auditory cortex (A1) responding to the frequency of the paired tone. However, the relationship between VNS intens...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2015.08.018
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Non-invasive direct current stimulation (DCS) of the brain induces functional plasticity in vitro and facilitates motor learning across species. The effect of DCS on structural synaptic plasticity is currently unknown. OBJECTIVE:This study addresses the effects and the underlying mechanisms of anodal DCS on...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2019.07.026
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Previous studies have shown that primary motor cortex (M1) excitability is modulated by motor skill learning and that the M1 plays a crucial role in motor memory. However, the following questions remain: (1) At what stage do changes in M1 excitability occur? (2) Are learning-induced changes in leg M1 excitab...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2015.07.025
更新日期：2015-11-01 00:00:00
abstract：:The intensity of sound emanating from the discharge of magnetic coils used in repetitive transcranial magnetic stimulation (rTMS) can potentially cause acoustic trauma. Per Occupational Safety and Health Administration (OSHA) standards for safety of noise exposure, hearing protection is recommended beyond restricted l...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2014.01.056
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:Transcranial direct current stimulation (tDCS) is an emerging non-invasive neuromodulation therapy in epilepsy with conflicting results in terms of efficacy and safety. OBJECTIVE:Review the literature about the efficacy and safety of tDCS in epilepsy in humans and animals. METHODS:We searched studies in Pu...
journal_title：Brain stimulation
pub_type： 杂志文章,评审
doi：10.1016/j.brs.2015.01.001
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:There is much interest in whether daily left prefrontal repetitive transcranial magnetic stimulation (rTMS) over several weeks may become a clinically useful antidepressant treatment. Although rTMS appears largely safe, many patients report that this procedure is somewhat painful, which may restrict its ulti...
journal_title：Brain stimulation
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.brs.2008.09.001
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:Neuroimaging studies suggest that facial expression recognition is processed in the bilateral posterior superior temporal sulcus (pSTS). Our recent repetitive transcranial magnetic stimulation (rTMS) study demonstrates that the bilateral pSTS is causally involved in expression recognition, although involveme...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2020.04.011
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Although cervical vagus nerve stimulation is effective for reducing infarct volume in rats, it is not feasible for acute human stroke as it requires surgical incision of the neck. We hypothesized that stimulation of the dermatome in the external ear innervated by the vagus nerve (auricular vagus nerve stimul...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2014.09.009
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Movies and television (TV) programs are an important source of public information about ECT. OBJECTIVE:To narratively review the portrayal of ECT in international movies and TV programs from 1948 until present. METHODS:Several Internet movie databases and a database of phrases appearing in movies and TV pr...
journal_title：Brain stimulation
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.brs.2016.07.005
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Directional Deep Brain Stimulation (D-DBS) allows axially asymmetric electrical field shaping, away from structures causing side-effects. However, concerns regarding the impact on device lifespan and complexity of the monopolar survey have contributed to sparing use of these features. OBJECTIVE:To investiga...
journal_title：Brain stimulation
pub_type： 临床试验,杂志文章
doi：10.1016/j.brs.2017.12.015
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Dopamine agonist therapy and deep brain stimulation (DBS) of the subthalamic nucleus (STN) are antiparkinsonian treatments that act on a different part of the basal ganglia-thalamocortical motor circuitry, yet produce similar symptomatic improvements. OBJECTIVE/HYPOTHESIS:The purpose of this study was to id...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2011.09.002
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:Deep brain stimulation (DBS) in the subcallosal cingulate gyrus (SCG) is becoming an effective therapeutic option for treatment resistant depression (TRD). OBJECTIVE/HYPOTHESIS:Identifying the neurophysiological mechanisms altered by DBS may lead to more tailored treatment parameters and enhanced efficacy. ...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2015.06.010
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:To assay peripheral inter-ictal cytokine serum levels and possible relations with non-invasive vagus nerve stimulation (nVNS) responsiveness in migraineurs. METHODS:This double-blinded, sham-controlled study enrolled 48 subjects and measured headache severity, frequency [headache days/month, number of total ...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2019.01.008
更新日期：2019-01-01 00:00:00
abstract：CONTEXT:The aim of this study was to assess whether the combination of low frequency repetitive transcranial magnetic stimulation (rTMS) and venlafaxine (150-225 mg/day) is effective and safe for treatment-resistant unipolar depression (TRD). METHOD:In a multicenter (18 centers) randomized double blind controlled tria...
journal_title：Brain stimulation
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.brs.2014.07.040
更新日期：2014-11-01 00:00:00
abstract：BACKGROUND:Although some studies have reported significant reductions in food cravings following the single-session of repetitive transcranial magnetic stimulation (rTMS), there is little research on the effects of multi-session of rTMS on food consumption and body weight in obese subjects. OBJECTIVE:We conducted 4-we...
journal_title：Brain stimulation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brs.2019.07.020
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:The use of repetitive transcranial magnetic stimulation (rTMS) as both therapeutic and experimental tools has grown enormously over the past decade. However, variability in response to rTMS is one challenge that remains to be solved. Estrogen can impact neural plasticity and may also affect plastic changes f...
journal_title：Brain stimulation
pub_type： 临床试验,杂志文章
doi：10.1016/j.brs.2019.05.007
更新日期：2019-01-01 00:00:00
abstract：:Inhibitory control mechanisms are important in a range of behaviours to prevent execution of motor acts which, having been planned, are no longer necessary or appropriate. Examples of this can be seen in a range of sports, such as cricket and baseball, where the choice between execution and inhibition of a bat swing m...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2012.03.012
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND:External trigeminal nerve stimulation (ETNS) is an emergent, non-invasive neurostimulation therapy delivered bilaterally with adhesive skin electrodes. In previous studies, ETNS was associated to a decrease in seizure frequency in patients with focal drug-resistant epilepsy (DRE). OBJECTIVE:To determine the...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2020.06.005
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (TMS) is a non-invasive, safe, and efficacious treatment for depression. TMS has been shown to normalize abnormal functional connectivity of cortico-cortical circuits in depression and baseline functional connectivity of these circuits predicts treatment response....
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2017.07.002
更新日期：2017-01-01 00:00:00
abstract：:Although rTMS is moving steadily into the mainstream as a treatment for medically refractory depression, its efficacy continues to lag behind that of more invasive neuromodulation treatments such as ECT or DBS. Here we review evidence to suggest that a fruitful, but neglected, strategy for improving rTMS efficacy may ...
journal_title：Brain stimulation
pub_type： 杂志文章,评审
doi：10.1016/j.brs.2012.08.006
更新日期：2013-05-01 00:00:00
