Abstract:
INTRODUCTION:The Kham Tibetans are one of several Tibetan ethnic subgroups living in the Kham area of China. Because studies on the high-altitude adaptation of the Kham people are scant, the main aim of this study is to investigate whether the response to hypoxia, especially polycythemia status, in the Kham Tibetans is different from other Tibetan ethnic subgroups. METHODS:The primary investigation was conducted on 346 native Kham Tibetan adults (268 men and 78 women) from 3 herdsmen villages located in Hongyuan County situated at an altitude of greater than 3600 m. The participants were aged 46.2±14.1 (21-82; mean±SD with range) years. Anthropometric measurements such as weight, height, waist circumference, body mass index, and blood pressure, as well as laboratory blood tests such as glycosylated hemoglobin, hemoglobin, total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and uric acid were analyzed. RESULTS:The concentrations of hemoglobin were 171.3±12.9 (66-229) mg·L-1 and 151.4±16.4 (86-190) mg·L-1 in men and women, respectively. The frequency of polycythemia was found to be 25.5 and 21.8% in men and women, respectively. Polycythemia was found to be significantly associated with glycosylated hemoglobin concentrations, hypertension, and hyperuricemia (P=0.002, 0.023, and 0.009, respectively). CONCLUSIONS:There is a higher frequency of polycythemia in the Kham Tibetans when compared with reported studies from other Tibetan ethnic subgroups living on the Qinghai-Tibet plateau.
journal_name
Wilderness Environ Medjournal_title
Wilderness & environmental medicineauthors
Zhang JB,Wang L,Chen J,Wang ZY,Cao M,Yie SM,Yang H,Yao XQ,Zeng Y,Yang YC,Xie CB,Zhao TQdoi
10.1016/j.wem.2017.09.010subject
Has Abstractpub_date
2018-03-01 00:00:00pages
18-28issue
1eissn
1080-6032issn
1545-1534pii
S1080-6032(17)30270-3journal_volume
29pub_type
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journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
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更新日期:2014-09-01 00:00:00
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