Abstract：
:A 47-year-old woman presented with a medial orbital tumor initially diagnosed as either a myxoid neurofibroma or myoepithelioma. Over 30 years the tumor recurred seven times and was serially debulked. Careful histopathologic analysis coupled with immunohistochemical studies performed on the last two biopsies established the rare diagnosis of a locally aggressive angiomyxoma (because of its local infiltrative growth) with myofibroblastic features (smooth muscle actin and calponin positivity and desmin negativity). The last recurrence manifested at a shorter interval than the earlier ones, suggesting an accelerating clinical course. By this late stage there was complete blindness, a frozen globe, and extreme, unmeasurable proptosis accompanied by massive chemosis and eyelid fullness. An exenteration was performed, and the orbital contents contained a persistent angiomyxoma, but additionally, another cellular population had emerged-mitotically active cells with a malignant rhabdoid phenotype (round shape, cytoplasmic hyaline/globoid inclusions composed of whorls of compact vimentin filaments as well as epithelial membrane antigen and focal cytokeratin positivity). This is the first orbital case of a rhabdoid transformation of a benign orbital mesenchymal tumor. Shortly after the exenteration, multifocal metastases, notably to the lungs, were found, leading to the introduction of chemotherapy, which was discontinued because of non-responsiveness of the tumor and patient intolerance. After 1 year of follow up, the patient is still alive, but has persistent active disease with widespread metastases and a guarded prognosis.
journal_name
Surv Ophthalmoljournal_title
Survey of ophthalmologyauthors
Jakobiec FA,Callahan AB,Stagner AM,Lee NG,Rashid A,Mendoza P,Grove A,Freitag SKdoi
10.1016/j.survophthal.2014.12.002subject
Has Abstractpub_date
2015-03-01 00:00:00pages
166-76issue
2eissn
0039-6257issn
1879-3304pii
S0039-6257(14)00256-2journal_volume
60pub_type
杂志文章,评审abstract：:We investigate the efficacy and safety of intravitreal injection (IVI) of antivascular endothelial growth factor agents and laser photocoagulation (LPC) for retinopathy of prematurity. We performed a systematic search of Ovid MEDLINE, EMBASE, and Cochrane CENTRAL (2005-2019). Comparative studies reporting on ocular ef...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2020.12.002
更新日期：2020-12-16 00:00:00
abstract：:Optical coherence tomography angiography (OCTA) is a new, noninvasive imaging technique that generates real-time volumetric data on chorioretinal vasculature and its flow pattern. With the advent of high-speed optical coherence tomography, established enface chorioretinal segmentation, and efficient algorithms, OCTA g...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2017.05.006
更新日期：2017-01-01 00:00:00
abstract：:There are numerous unresolved issues and controversies regarding the management of open-globe injuries involving the posterior segment. These areas include, but are not limited to, the following issues. Although vitrectomy has been shown to improve visual outcomes and allow retention of the eye in many cases, the exte...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0039-6257(99)00104-6
更新日期：1999-11-01 00:00:00
abstract：:Optic nerve hemangioblastoma is a rare tumor that is usually unilateral and most commonly occurs in the context of von Hippel-Lindau disease. Differential diagnosis is based on clinical history and imaging. Magnetic resonance imaging with gadolinium enhancement is the most useful imaging modality as it can reveal flow...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2018.10.002
更新日期：2019-01-01 00:00:00
abstract：:Wavefront sensors and scanning laser technology are enabling the correction of the aberrations of the eye. The effects of aberrations on visual performance are reviewed, and the theoretical limit of visual performance is predicted to understand the ultimate endpoint of these new technologies. A schematic eye model tha...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0039-6257(00)00145-4
更新日期：2000-09-01 00:00:00
abstract：:Angiogenesis is a complex biologic process that occurs normally in development and in turnover and remodeling of mature vascular networks. Pathological angiogenesis and neovascularization occur in association with retinal and ocular ischemic diseases, in retinopathy of prematurity and other developmental disorders, an...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0039-6257(96)82014-5
更新日期：1996-05-01 00:00:00
abstract：:The use of intravitreal (IVT) corticosteroids for treatment of posterior segment diseases has increased significantly over the last decade. A commonly recognized complication of IVT steroids is secondary ocular hypertension (OHT) that can occur immediately secondary to direct intraocular volume increase or weeks to mo...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.survophthal.2012.08.003
更新日期：2013-07-01 00:00:00
abstract：:A two-year-old full-term boy with a history of an intermittent exotropia presented to the pediatric ophthalmology clinic for routine follow-up. He was found to have a stable sensorimotor examination however dilated funduscopic examination of the right eye was significant for a dim foveal reflex with a new discrete, wh...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2020.12.003
更新日期：2020-12-10 00:00:00
abstract：:Thymoxamine is an alpha-adrenergic blocking agent which works by competitive antagonism of norepinephrine. It is the only alpha-adrenergic blocker available which has tolerable side effects when used as an ophthalmic solution. When used as a 0.5% solution it consistently produces miosis without affecting the intraocul...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0039-6257(80)90150-2
更新日期：1980-09-01 00:00:00
abstract：:Drugs across many pharmacologic classes induce corneal epithelial changes. Many of these drugs have cationic amphiphilic structures, with a hydrophobic ring and hydrophilic cationic amine side chain that allow them to cross cell membranes. These drugs lead to intracellular phospholipid accumulation, often manifested i...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2016.11.008
更新日期：2017-01-01 00:00:00
abstract：:To diagnose the cause of chronic unilateral external ocular inflammation, the physician must take into account many factors usually not considered in bilateral cases. We report on the diagnosis and treatment of ten unilateral cases encompassing a variety of ocular and systemic problems. The purpose of this report is t...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/0039-6257(79)90019-5
更新日期：1979-11-01 00:00:00
abstract：:Viral conjunctivitis caused by adenovirus is the most common infectious conjunctivitis. Adenoviruses are highly contagious pathogens. The modes of transmission are mainly through hand to eye contact, ocular secretions, respiratory droplets, and contact with ophthalmic care providers and their medical instruments. The ...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2015.04.001
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:Laser photocoagulation treatment of the posterior pole of the retina is often complicated by immediate visual impairment, which is caused by the unavoidable laser-induced destruction of the normal tissue adjacent to the lesion. A neuroprotective therapy aimed at salvaging this normal tissue might enhance the ...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0039-6257(99)00093-4
更新日期：1999-10-01 00:00:00
abstract：:Detachment of the retinal pigment epithelium is a prominent feature of many chorio-retinal disease processes, the most prevalent of which is age-related macular degeneration (AMD). Detachment of the retinal pigment epithelium may or may not be associated with choroidal neovascularization and may be caused by different...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2007.02.008
更新日期：2007-05-01 00:00:00
abstract：:Adjunctive therapy for the management of glaucoma is commonly used. Unfixed combinations of the prostaglandin analog latanoprost and other glaucoma medications have been demonstrated to effectively lower intraocular pressure (IOP). The range of reported additional reductions in IOP compared to a monotherapy baseline a...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0039-6257(02)00295-3
更新日期：2002-08-01 00:00:00
abstract：:The optical considerations of intraocular lenses can be understood, using only the formulae and principles taught in a typical basic science course in ophthalmology. Some of the more common optical problems associated with intraocular lenses are presented and the methods for their solutions are illustrated and explain...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/0039-6257(79)90146-2
更新日期：1979-07-01 00:00:00
abstract：PURPOSE:The angiostatic cortisene anecortave acetate was evaluated in three safety and efficacy studies of patients with subfoveal choroidal neovascularization secondary to exudative age-related macular degeneration. METHODS:The Anecortave Acetate Monotherapy Trial enrolled 128 patients randomized to anecortave acetat...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2006.11.005
更新日期：2007-01-01 00:00:00
abstract：:Optic disk imaging is integral to the diagnosis and treatment of patients with glaucoma. We discuss the various forms of imaging the optic nerve, including ophthalmoscopy, photography, and newer imaging modalities, including optical coherence tomography (OCT), confocal scanning laser ophthalmoscopy (HRT), and scanning...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.survophthal.2013.10.004
更新日期：2014-07-01 00:00:00
abstract：:William Ellergy Briggs was California's preeminent ophthalmologist for more than fifty years. A student of Ernst Fuchs, he was a clinician, scholar, and innovator who transplanted the best of European ophthalmology to the Western United States. ...
journal_title：Survey of ophthalmology
pub_type： 传,历史文章,杂志文章
doi：10.1016/0039-6257(90)90029-u
更新日期：1990-01-01 00:00:00
abstract：:Giant cell arteritis (GCA) is a medium-to-large vessel vasculitis with potentially sight- and life- threatening complications. Our understanding of the pathogenesis, diagnosis, and treatment of GCA has advanced rapidly in recent times. The validity of using the American College of Rheumatology guidelines for diagnosis...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2016.01.001
更新日期：2016-07-01 00:00:00
abstract：:Since its inception in the late 1990s, corneal cross-linking has grown from an interesting concept to a primary treatment for corneal ectatic disease worldwide. Using a combination of ultraviolet-A light and a chromophore (vitamin B2, riboflavin), the cornea can be stiffened, usually with a single application, and pro...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2015.04.002
更新日期：2015-11-01 00:00:00
abstract：:Typical optic neuritis is an idiopathic demyelinating condition that is often associated with multiple sclerosis. This has been well characterized and has an excellent prognosis. Atypical optic neuritis can result from an inflammatory, infectious, or autoimmune disorder. Differentiating the two types of optic neuritis...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2019.06.001
更新日期：2019-01-01 00:00:00
abstract：:The growth of the eye results in a myopic shift in aphakic and pseudophakic eyes during childhood. Cataract surgery after the age of 6 months, with or without lens implantation, appears to have little effect on the rate of refractive growth. Most children with pseudophakia have a large amount of myopic shift. This myo...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.survophthal.2009.07.001
更新日期：2010-03-01 00:00:00
abstract：:Despite the improving results that have been noted with penetrating keratoplasty, graft failure remains a significant problem. The causes of graft failure are quite varied. Primary donor failure, surgical complications, intraocular lens complications, persistent epithelial defects, allograft rejection, infection, glau...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0039-6257(90)90110-h
更新日期：1990-03-01 00:00:00
abstract：:Oxidative stress is one of the main mechanisms of lens opacification, and certain nutritional antioxidants are suspected to have a protective effect. To examine the role of these nutritional antioxidants on cataract prevention, we searched major databases and reviewed current evidence regarding the protective effect o...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,meta分析
doi：10.1016/j.survophthal.2019.03.003
更新日期：2019-01-01 00:00:00
abstract：:A ten-day ophthalmology clerkship for third-year medical students is described. The curriculum, detailed in a day-by-day syllabus, sets specific student goals, evaluates attainment of the goals by a pre-post test, utilizes a student-oriented study guide keyed to major textbrooks as core material with slide-tape and vi...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/0039-6257(77)90090-x
更新日期：1977-09-01 00:00:00
abstract：:The court decisions included in this article reflect judicial attitudes towards medicolegal cases in most states. The courts have defined and amplified issues of informed consent, the physician's duty to warn patients and protect third parties, the limitations of the "Good Samaritan" statute, the responsibility of the...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/0039-6257(87)90071-3
更新日期：1987-07-01 00:00:00
abstract：:Technologic improvements in cataract surgery have not only improved visual outcomes, but also have minimized intraoperative and postoperative pain. We review the mechanisms, risk factors, and management of intraoperative and postoperative pain. Summaries of less common sources of physiologic pain have been included to...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2017.07.002
更新日期：2018-01-01 00:00:00
abstract：:Through the efforts of Dr. Townley Paton, eye banks were founded in New York in the early 1940s. Since that time there has been steady growth in both the supply of and demand for donor material. A number of factors have contributed to the success of eye banks in the U.S.A., including improvements in eye banking techni...
journal_title：Survey of ophthalmology
pub_type： 历史文章,杂志文章
doi：10.1016/0039-6257(82)90151-5
更新日期：1989-01-01 00:00:00
abstract：:Age-related macular degeneration (AMD) is one of the leading causes of blindness worldwide with increasing prevalence owing to increased life expectancy. Intravitreal injections of antivascular endothelial growth factor agents are commonly used in exudative AMD and oral antioxidant medication for nonexudative AMD; how...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2020.08.005
更新日期：2020-09-21 00:00:00
