Cognitive Dysfunction in Patients With Late-Life Somatic Symptom Disorder: A Comparison According to Disease Severity.

Abstract:

BACKGROUND:Late-life somatic symptom disorder (SSD) is characterized by various aging-associated factors, such as a functional decline, psychosocial problems, and cognitive dysfunction. However, the details of the cognitive dysfunction that occur in late-life SSD are still unknown. OBJECTIVE:The aims of this study were to reveal the cognitive profile of patients with late-life SSD and to evaluate how cognitive dysfunction affects disease severity. METHODS:We compared the cognitive profiles of patients with late-life SSD (n = 40) with those of normal control subjects (n = 21). In addition, we divided the patients with late-life SSD into mild-to-moderate (n = 24) and severe (n = 16) groups and compared the cognitive profiles of the 3 groups. RESULTS:Patients with late-life SSD exhibited a lower Mini-Mental State Examination total score and attention decline. In the 3-group comparison, the severe group had a lower Mini-Mental State Examination score and Frontal Assessment Battery score than the normal control group, whereas no significant difference was seen between the mild-to-moderate and the normal control groups. CONCLUSIONS:Our data suggest that different cognitive patterns may exist depending on disease severity, possibly indicating differences in pathogenesis.

journal_name

Psychosomatics

journal_title

Psychosomatics

authors

Inamura K,Shinagawa S,Nagata T,Tagai K,Nukariya K,Nakayama K

doi

10.1016/j.psym.2014.10.004

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

486-94

issue

5

eissn

0033-3182

issn

1545-7206

pii

S0033-3182(14)00164-9

journal_volume

56

pub_type

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