Abstract:
PURPOSE OF REVIEW:Women are more impacted by Alzheimer's disease than men - they are at significantly greater risk of developing Alzheimer's disease, and recent research shows that they also appear to suffer a greater cognitive deterioration than men at the same disease stage. The purpose of this article is to review recent studies on examining sex differences in cognitive function in Alzheimer's disease. RECENT FINDINGS:We searched electronically for articles, reviews and meta-analyses published between 1/2016 and 12/2017 and identified 298 articles on sex differences in cognition in Alzheimer's disease. The key themes to emerge were sex differences in cognitive function, risk factors, resilience, and cognitive reserve. SUMMARY:Evidence is steadily and increasingly accumulating to confirm the poorer cognitive outcome for women than men with Alzheimer's disease. Although small in size, the effects occur across a broad range of cognitive domains including visuospatial, verbal, episodic memory, and semantic memory - some of which typically reveal a sex-related processing advantage for healthy women. Explanations have been linked to a variety of factors including differences in cognitive reserve, resilience, as well as genetics (apolipoprotein ε4) and functional and structural brain changes. Sex-related differences in risk factors, resilience, cognitive reserve, and rates of deterioration have implications for clinical practice.
journal_name
Curr Opin Psychiatryjournal_title
Current opinion in psychiatryauthors
Laws KR,Irvine K,Gale TMdoi
10.1097/YCO.0000000000000401subject
Has Abstractpub_date
2018-03-01 00:00:00pages
133-139issue
2eissn
0951-7367issn
1473-6578journal_volume
31pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:This article reviews recent literature published over the period March 2012-August 2013 on antidepressant pharmacogenetics, with a focus on clinical translation and methodological challenges. RECENT FINDINGS:Recently, various polymorphisms associated with differential antidepressant efficacy, tolerab...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000023
更新日期:2014-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this study is to provide a review of articles published between July 2007 and August 2008 on the current use and rationale of benzodiazepines in anxiety disorders. RECENT FINDINGS:Recent review articles confirm selective serotonin reuptake inhibitors as first-choice drugs for treating anxi...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e32831a473d
更新日期:2009-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Overview on integrated care trials focusing on effectiveness and efficiency published from 2011 to 2013. RECENT FINDINGS:Eight randomized controlled trials (RCTs) and 21 non-RCT studies were published from 2011 to 2013. Studies differed in several methodological aspects such as study population, psyc...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e328361ec3b
更新日期:2013-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The International Classification of Diseases, 11th Edition (ICD-11) classifies personality disturbance according to levels of severity. This article reviews the literature on levels of personality functioning in relation to clinical management and treatment, and proposes how these findings apply to th...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000658
更新日期:2021-01-01 00:00:00
abstract:PURPOSE OF REVIEW:To summarize research into public policy affecting people with intellectual and developmental disabilities, published in 2009 and early 2010. RECENT FINDINGS:There is a growing body of international policy relating to intellectual disability, usually expressed as general moral objectives. However, th...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e32833be998
更新日期:2010-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The perinatal period introduces a myriad of changes. One important but often overlooked change is the increased risk for sleep disturbance. Although casually regarded as a consequence of pregnancy or postpartum, there is emerging evidence to suggest that women with significant sleep disturbance, chara...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000206
更新日期:2015-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To understand the current situation, needs and challenges in the area of postgraduate training in psychiatry in Asia and identify implementable solutions.Leaders in psychiatric education from nine Asia Pacific countries prepared country reports, based on a suggested list of items and met for a day to ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000444
更新日期:2018-09-01 00:00:00
abstract:PURPOSE OF REVIEW:This work reviews recent research regarding treatment of fragile X syndrome (FXS), the most common inherited cause of intellectual disability and autism spectrum disorder. The phenotype includes anxiety linked to sensory hyperarousal, hyperactivity, and attentional problems consistent with attention d...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000131
更新日期:2015-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Bariatric surgery is the most effective treatment for morbid obesity. However, 20-30% of patients undergoing bariatric surgery experience premature weight stabilization or weight regain postoperatively. We report on the recent literature of predictors of weight loss and the efficacy of cognitive behav...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000359
更新日期:2017-11-01 00:00:00
abstract:PURPOSE OF REVIEW:This review summarizes recent progress in the diagnosis and management of irritable bowel syndrome, with a focus on dietary and microbiota aspects. RECENT FINDINGS:From a pathophysiological point of view, IBS is a multifactorial condition with both peripheral (transit) as central (visceral hypersensi...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000628
更新日期:2020-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The development of acute and posttraumatic stress symptoms after a traumatic event is common and often leads to personal distress, functional impairment, and economic consequences in trauma victims and their loved ones. Hence, the prevention of acute and chronic posttraumatic stress is an important pu...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e32834cdde2
更新日期:2011-11-01 00:00:00
abstract:PURPOSE OF REVIEW:There has been increased interest in the relationship between religion and spirituality and mental health in recent years. This article reviews recent research into the capacity of religion and spirituality to benefit or harm the mental health of believers. We also examine the implications this may ha...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000080
更新日期:2014-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Females experience eating disorders at substantially higher rates than males. Although sociocultural factors have traditionally been thought to underlie this sex disparity, accumulating evidence implicates differential exposure to gonadal hormones early in life. Gonadal hormones also impact within-sex...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000543
更新日期:2019-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Policies that limit young people's access to cannabis may reduce early onset of use and minimize health-related harm. This review article provides an update of recent research examining the influence of the cannabis policy frameworks on the use of cannabis by young people. RECENT FINDINGS:There are s...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000253
更新日期:2016-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Recent policy and legislative developments confirm the right to advocacy for people experiencing mental health problems. Provision of mental health advocacy for black and minority ethnic communities is particularly identified as a key objective for Primary Care Trusts. This review considers the implic...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e3282f0abf0
更新日期:2007-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The present review focuses on atypical antipsychotics and tardive dyskinesia. RECENT FINDINGS:We have known for many years that clozapine has a diminished risk of tardive dyskinesia compared with typical antipsychotics. The last decade has seen the introduction of a number of other atypical antipsych...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e328017f6b1
更新日期:2007-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Public health concern regarding the nonmedical use of prescription stimulants among youth has generated the need for increased understanding of diversion, which is the illegal sharing and selling of prescription drugs. Although our understanding of nonmedical use of stimulants has increased, the same ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000172
更新日期:2015-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Clinical practice guidelines (CPGs) do not usually offer a sex-specific approach for the management of schizophrenia. With this narrative review, we aim to give an integrated and synthesized overview of the current state of knowledge regarding sex-specific aspects in schizophrenia and how this topic m...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000597
更新日期:2020-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Social cognition refers broadly to the way in which we process social information, and is a critical predictor of social competency. This article provides an overview of some of the assessment approaches that have been developed to assess this construct. RECENT FINDINGS:A variety of well validated as...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000139
更新日期:2015-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Behavioral medicine is an interdisciplinary field, integrating research from a variety of disciplines. This review focuses on recent advances and developments in behavioral medicine. RECENT FINDINGS:Stress, as well as having a role in the etiology and maintenance of somatic disease and somatoform dis...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/01.yco.0000214345.37002.77
更新日期:2006-03-01 00:00:00
abstract:PURPOSE OF REVIEW:To understand pathways into healthcare people of minority ethnic groups use and if these differ from those of the majority. RECENT FINDINGS:The current literature shows that some forms of treatment are seen as less stigmatizing and more acceptable. The treatment expectations also dictate choice of he...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e3283477ae8
更新日期:2011-07-01 00:00:00
abstract:PURPOSE OF REVIEW:To review recent neuro-imaging findings with respect to conduct disorder and callous-unemotional traits in childhood and comparable psychopathy in adult-hood that deepen the literature in important ways. RECENT FINDINGS:Recent structural findings particularly bring clarity to the literature. First, t...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000559
更新日期:2020-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Progress in neurosciences, increasing computational power, and ongoing miniaturization of micro-technological components enable both a better understanding of human brain functions and development of new diagnostic and therapeutic tools. Research and development as well as clinical application of devi...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e32834bb8ca
更新日期:2011-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Screening measures for bipolar disorder are positioned as playing an important role in improving diagnostic accuracy. This review considers the principal screening measures developed over the past decade. RECENT FINDINGS:Although the development and evaluation of bipolar screening measures were disti...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000125
更新日期:2015-01-01 00:00:00
abstract:PURPOSE OF REVIEW:This review aims to summarize data published in the scientific literature and available on official websites on fetal alcohol spectrum disorder (FASD) in Africa. RECENT FINDINGS:There is a paucity of published literature and evidence-based information on prenatal exposure to alcohol in the African co...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章
doi:10.1097/YCO.0000000000000315
更新日期:2017-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The present article reviews the increasing literature on comorbidity, treatment and use of health service resources for children and adolescents with autism spectrum disorders and intellectual disability from January 2006 to January 2007. RECENT FINDINGS:Children and adolescents with autism spectrum ...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0b013e32821f6095
更新日期:2007-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Compelling evidence suggests that a small group of men who develop schizophrenia display a stable pattern of antisocial behaviour from childhood onwards, causing considerable suffering to victims and to themselves and imposing a significant financial burden on society. We reviewed the literature on th...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/01.yco.0000238484.12023.aa
更新日期:2006-09-01 00:00:00
abstract:PURPOSE OF REVIEW:We reviewed the recent literature on prevalence rates, and application of evidence-based treatments for eating disorders among Hispanics/Latinos residing in the United States. RECENT FINDINGS:Lifetime prevalence rates of anorexia nervosa are lower among Hispanic/Latinos than non-Hispanic Whites. Ther...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000277
更新日期:2016-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Multiple lines of evidence support the conceptualization of bipolar disorder as a disorder of circadian rhythms. Considering bipolar disorder in the framework of circadian disturbances also helps understand the clinical phenomenology pointing toward a multisystemic involvement. RECENT FINDINGS:Patien...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000108
更新日期:2014-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Mental disorders are mainly characterized via symptom assessment. Symptoms are state-like macroscopic anomalies of behaviour, experience, and expression that are deemed relevant for diagnostic purposes. An alternative approach is based on the concept of endophenotypes, which are physiological or behav...
journal_title:Current opinion in psychiatry
pub_type: 杂志文章,评审
doi:10.1097/YCO.0000000000000059
更新日期:2014-05-01 00:00:00