Abstract:
:Amblyopia is a visual disorder caused by poorly coordinated binocular input during development. Little is known about the impact of amblyopia on the white matter within the visual system. We studied the properties of six major visual white-matter pathways in a group of adults with amblyopia (n=10) and matched controls (n=10) using diffusion weighted imaging (DWI) and fiber tractography. While we did not find significant differences in diffusion properties in cortico-cortical pathways, patients with amblyopia exhibited increased mean diffusivity in thalamo-cortical visual pathways. These findings suggest that amblyopia may systematically alter the white matter properties of early visual pathways.
journal_name
Vision Resjournal_title
Vision researchauthors
Allen B,Spiegel DP,Thompson B,Pestilli F,Rokers Bdoi
10.1016/j.visres.2014.12.021subject
Has Abstractpub_date
2015-09-01 00:00:00pages
48-55eissn
0042-6989issn
1878-5646pii
S0042-6989(15)00005-Xjournal_volume
114pub_type
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