Sleep and survival among women with breast cancer: 30 years of follow-up within the Nurses' Health Study.

abstract：:Human dialysable Transfer Factor (TFd) extracted from lymphocytes of patients with transitional cell carcinoma of bladder (TCCB) was replicated in culture by lymphoblastoid cell lines. The effectiveness of two such TFdLs produced in vitro in transferring sensitivity to TCCB was assessed in the lymphocyte migration tes...

journal_title：British journal of cancer

authors： Pizza G,Viza D,Boucheix C,Corrado F

更新日期：1976-06-01 00:00:00

abstract：:Fifteen patients with acute myelogenous leukaemia were studied to determine if their remission blood leucocytes could be stimulated into taking up [3H] thymidine after in vitro culture with their own cryo-preserved irradiated AML leukaemia cells. In 6/15 patients it was possible to show autologous recognition and equa...

journal_title：British journal of cancer

authors： Cocks P,Powles RL,Chapuis B,Alexander P

更新日期：1977-03-01 00:00:00

abstract：:Insulin-like growth factors (IGFs) I and II are implicated in progression of various tumours including colorectal carcinomas. To interfere with the production of IGFs, we treated male nude mice bearing xenografts of HT-29 human colon cancer with various potent growth hormone-releasing hormone (GH-RH) antagonists. Twic...

journal_title：British journal of cancer

authors： Szepeshazi K,Schally AV,Groot K,Armatis P,Halmos G,Herbert F,Szende B,Varga JL,Zarandi M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Head and neck squamous cell carcinoma (HNSCC) patients frequently develop treatment resistance to cetuximab, a monoclonal antibody against EGFR, as well as radiotherapy. Here we addressed extracellular signal-regulated kinase 1/2 (ERK1/2) regulation by cetuximab or fractionated irradiation (IR) and conducted...

journal_title：British journal of cancer

authors： Rong C,Muller MF,Xiang F,Jensen A,Weichert W,Major G,Plinkert PK,Hess J,Affolter A

更新日期：2020-07-01 00:00:00

abstract：:The assessment of a tumour's angiogenic potential, by measuring the microvessel density in histological sections, assumes that a 4-microm section is representative of whole tumour vascularity. This study has examined this assumption by comparing the vessel density found radiologically, after injecting specimens with c...

journal_title：British journal of cancer

authors： Martin L,Holcombe C,Green B,Leinster SJ,Winstanley J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Breast cancer, a heterogeneous disease has been broadly classified into oestrogen receptor positive (ER+) or oestrogen receptor negative (ER-) tumour types. Each of these tumours is dependent on specific signalling pathways for their progression. While high levels of survivin, an anti-apoptotic protein, incr...

journal_title：British journal of cancer

authors： Pervin S,Tran L,Urman R,Braga M,Parveen M,Li SA,Chaudhuri G,Singh R

更新日期：2013-03-05 00:00:00

abstract：:A bispecific monoclonal antibody recognising both carcinoembryonic antigen (CEA) and ricin toxin A chain (RTA) was tested for its ability to target recombinant RTA (r-RTA) to CEA-expressing tumour cells, alone and in combination with ricin B chain (RTB). The antibody, 636 (Robins et al., 1990), induced significant RTA...

journal_title：British journal of cancer

authors： Embleton MJ,Charleston A,Robins RA,Pimm MV,Baldwin RW

更新日期：1991-05-01 00:00:00

abstract：:High levels of loss of distal markers on 17p13.3 in breast cancer suggested the presence within the region of at least one tumour-suppressor gene. Here we describe the derivation of two biallelic polymorphisms from the 17p telomeric yeast artificial chromosome (YAC) TYAC98. Polymerase chain reaction-restriction fragme...

journal_title：British journal of cancer

authors： White GR,Stack M,Santibáñez-Koref M,Liscia DS,Venesio T,Wang JC,Helms C,Donis-Keller H,Betticher DC,Altermatt HJ,Hoban PR,Heighway J

更新日期：1996-09-01 00:00:00

abstract：:Expression of the 37-kDa laminin binding protein (37LBP/p40), a precursor of the 67-kDa laminin receptor, is well-correlated with the biological aggressiveness of cancer cells. To elucidate the direct role played by 37LBP/p40 in cancer cells, a murine lung cancer cell line T11, the 37LBP/p40 expression of which was re...

journal_title：British journal of cancer

authors： Satoh K,Narumi K,Abe T,Sakai T,Kikuchi T,Tanaka M,Shimo-Oka T,Uchida M,Tezuka F,Isemura M,Nukiwa T

更新日期：1999-06-01 00:00:00

abstract：:In haemagglutination tests we have found that the monoclonal antibody B5 discriminates between erythrocytes from patients with malignant cancer (total 386; greater than 80% B5 positive) and individuals with no known tumour (total 247; less than 20% B5 positive). The B5 antigen detected on intact erythrocytes is a tigh...

journal_title：British journal of cancer

authors： Metcalfe S,Milner J,Svvennsen RJ

更新日期：1984-03-01 00:00:00

abstract：:The goal of the study was to identify any normal genes that may become inactivated in malignant cells, with associated modifications or loss of gene products. Consequently, attempts were made to identify such products by generating monoclonal antibodies using an immune tolerisation-immunisation procedure. Using such a...

journal_title：British journal of cancer

authors： Imam SA,Stampfer MR,Yilmaz A,Taylor CR

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:The arachidonic acid metabolite 12(S)-HETE is suspected to enhance metastatic spread by inducing cancer cell- and lymph endothelial cell (LEC) motility. However, the molecular mechanisms leading to 12(S)-HETE-triggered cell migration are still elusive. METHODS:To delineate the signalling pathways involved i...

journal_title：British journal of cancer

authors： Nguyen CH,Stadler S,Brenner S,Huttary N,Krieger S,Jäger W,Dolznig H,Krupitza G

更新日期：2016-07-26 00:00:00

abstract：BACKGROUND:To quantify the benefits (cancer prevention and down-staging) and harms (recall and excess treatment) of cervical screening starting from age 20 years rather than from age 25 years. METHODS:We use routine screening and cancer incidence statistics from Wales (for screening from age 20 years) and England (scr...

journal_title：British journal of cancer

authors： Landy R,Birke H,Castanon A,Sasieni P

更新日期：2014-04-02 00:00:00

abstract：:Endosialin is a transmembrane glycoprotein selectively expressed in blood vessels and stromal fibroblasts of various human tumours. It has been functionally implicated in angiogenesis, but the factors that control its expression have remained unclear. As insufficient delivery of oxygen is a driving force of angiogenes...

journal_title：British journal of cancer

authors： Ohradanova A,Gradin K,Barathova M,Zatovicova M,Holotnakova T,Kopacek J,Parkkila S,Poellinger L,Pastorekova S,Pastorek J

更新日期：2008-10-21 00:00:00

abstract：:Nabilone, a synthetic cannabinoid, and Prochlorperazine were compared in a double-blind crossover study of 34 patients with lung cancer undergoing a 3-day schedule of chemotherapy with Cyclophosphamide, Adriamycin and Etoposide. Symptom scores were significantly better for patients on nabilone for nausea, retching and...

journal_title：British journal of cancer

authors： Ahmedzai S,Carlyle DL,Calder IT,Moran F

更新日期：1983-11-01 00:00:00

abstract：:In a cohort of 29,584 residents of Linxian, China, followed from 1985 to 2001, we conducted a case-cohort study of the magnitude of the association of Helicobacter pylori seropositivity with cancer risk in a random sample of 300 oesophageal squamous cell carcinomas, 600 gastric cardia adenocarcinomas, all 363 diagnose...

journal_title：British journal of cancer

authors： Kamangar F,Qiao YL,Blaser MJ,Sun XD,Katki H,Fan JH,Perez-Perez GI,Abnet CC,Zhao P,Mark SD,Taylor PR,Dawsey SM

更新日期：2007-01-15 00:00:00

abstract：:Pulmonary metastasectomy is widely and increasingly practiced in the belief that this intervention can cure patients with colorectal cancer, and that without it few survive 5 years. No good evidence exists supporting such convictions, indeed recent trial results challenge them. What evidence underpins this acceptance ...

journal_title：British journal of cancer

authors： Macbeth F,Fallowfield L

更新日期：2020-08-01 00:00:00

abstract：:Neuroendocrine tumours (NETs) comprise a heterogenous group of malignancies with an often unpredictable course, and with limited treatment options. Thus, new diagnostic, prognostic, and therapeutic markers are needed. To shed new lights into the biology of NETs, we have by cDNA transcript profiling, sought to identify...

journal_title：British journal of cancer

authors： Hofsli E,Wheeler TE,Langaas M,Laegreid A,Thommesen L

更新日期：2008-10-21 00:00:00

abstract：:Decreased accumulation of the fluorescent dye BCECF [2', 7'-bis-(2-carboxyethyl)-5-(6)- carboxyfluorescein] characterized murine and human multidrug-resistant cell lines overexpressing the multidrug resistance protein (MRP). Indomethacin (10 microM), a known cyclo-oxygenase and glutathione-S-transferase inhibitor as w...

journal_title：British journal of cancer

authors： Draper MP,Martell RL,Levy SB

更新日期：1997-01-01 00:00:00

abstract：:Currently, there are no effective biomarkers for ovarian cancer prognosis or prediction of therapeutic response. The objective of this study was to examine a panel of 10 serum biochemical parameters for their ability to predict response to chemotherapy, progression and survival of ovarian cancer patients. Sera from ov...

journal_title：British journal of cancer

authors： Oikonomopoulou K,Li L,Zheng Y,Simon I,Wolfert RL,Valik D,Nekulova M,Simickova M,Frgala T,Diamandis EP

更新日期：2008-10-07 00:00:00

abstract：:We examined a panel of 25 small cell lung cancer (SCLC) cell lines and nude mouse xenografts for expression of the proto-oncogenes c-met and c-kit, and for expression of the corresponding ligands, hepatocyte growth factor (HGF) (also known as scatter factor (SF)), and stem cell factor (SCF), respectively. Expression o...

journal_title：British journal of cancer

authors： Rygaard K,Nakamura T,Spang-Thomsen M

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Several tyrosine kinase inhibitors (TKIs) can decrease docetaxel clearance in patients by an unknown mechanism. We hypothesised that these interactions are mediated by the hepatic uptake transporter OATP1B1. METHODS:The influence of 16 approved TKIs on transport was studied in vitro using HEK293 cells expre...

journal_title：British journal of cancer

authors： Hu S,Mathijssen RH,de Bruijn P,Baker SD,Sparreboom A

更新日期：2014-02-18 00:00:00

abstract：:In the endeavour to develop a model for studying gene therapy of cancers associated with human papillomaviruses (HPVs), mouse cells were transformed with the HPV type 16 (HPV16) and activated H-ras oncogenes. This was done by cotransfection of plasmid p16HHMo, carrying the HPV16 E6/E7 oncogenes, and plasmid pEJ6.6, ca...

journal_title：British journal of cancer

authors： Smahel M,Sobotková E,Bubeník J,Símová J,Zák R,Ludviková V,Hájková R,Kovarík J,Jelínek F,Povýsil C,Marinov J,Vonka V

更新日期：2001-02-02 00:00:00

abstract：:Mediastinal masses include a wide variety of tumours and remain an interesting diagnostic challenge for radiologist. We performed positron emission tomography (PET) studies of primary mediastinal tumours in order to predict the malignancy of these tumours preoperatively. Twenty-two patients with primary mediastinal tu...

journal_title：British journal of cancer

authors： Kubota K,Yamada S,Kondo T,Yamada K,Fukuda H,Fujiwara T,Ito M,Ido T

更新日期：1996-04-01 00:00:00

abstract：:As regulators of malignant cell behaviour and communication with stroma, cytokines have proved useful in understanding cancer biology and developing novel therapies. In renal cell carcinoma, patients with inflammatory reactions are known to have poor prognosis. In order to elucidate the relation between renal cell car...

journal_title：British journal of cancer

authors： Yoshida N,Ikemoto S,Narita K,Sugimura K,Wada S,Yasumoto R,Kishimoto T,Nakatani T

更新日期：2002-05-06 00:00:00

abstract：:The effect of an antiserum containing antibodies against cell surface components of PyBHK cells on the action of certain anticancer agents has been studied using a colony formation inhibition assay. The effects of x-rays, chlorambucil, CCNU and possibly ICRF 159 are augmented by the antiserum whereas methotrexate and ...

journal_title：British journal of cancer

authors： Rubens RD,Vaughan-Smith S,Dulbecco R

更新日期：1975-09-01 00:00:00

abstract：:The development of an altered stromal microenvironment is a common feature of many tumours including squamous cell carcinoma (SCC), and there is increasing evidence that these changes in the stroma, which include increased expression of proteases and cytokines, may actually promote tumour progression. A common finding...

journal_title：British journal of cancer

authors： Lewis MP,Lygoe KA,Nystrom ML,Anderson WP,Speight PM,Marshall JF,Thomas GJ

更新日期：2004-02-23 00:00:00

abstract：BACKGROUND:Bortezomib is a proteasome inhibitor with minimal clinical activity as a monotherapy in solid tumours, but its combination with other targeted therapies is being actively investigated as a way to increase its anticarcinogenic properties. Here, we evaluate the therapeutic potential of co-treatment with bortez...

journal_title：British journal of cancer

authors： Taylor-Harding B,Agadjanian H,Nassanian H,Kwon S,Guo X,Miller C,Karlan BY,Orsulic S,Walsh CS

更新日期：2012-01-17 00:00:00

abstract：:A CD34-negative haematopoietic progenitor cell line, D064, derived from canine bone marrow stromal cells is able to differentiate into haematopoietic progenitors under the influence of growth factor-mediated signalling. While differentiating, these cells eventually start to express MHC class II molecules (DR homologue...

journal_title：British journal of cancer

authors： Huss R,Theis S,Deeg HJ

更新日期：1999-11-01 00:00:00

abstract：:Caffeine has for many years been known to be involved in the sensitization of DNA to damage. One potential mechanism recently put forward is an override of the G2/M block induced by irradiation, which would leave the cells less time for DNA repair prior to mitosis. However, different cell types display a variety of re...

journal_title：British journal of cancer

authors： Deplanque G,Vincent F,Mah-Becherel MC,Cazenave JP,Bergerat JP,Klein-Soyer C

更新日期：2000-08-01 00:00:00