Abstract:
:The purpose of this review is to give useful information to guide clinicians when treating pregnant women affected by bipolar disorder. This review focuses on mood stabilizers including lithium, sodium valproate, carbamazepine, oxcarbazepine, gabapentin, lamotrigine and topiramate. Data have been extracted from a MEDLINE search. Data from prospective, retrospective and case-control studies as well as systematic reviews, meta-analysis and data from Pregnancy Registry were included. Major congenital malformations as well as specific malformations were reported for each drug. Preliminary findings seem to identify lamotrigine as one ofthe safest antiepileptic drugs to be used in pregnancy. Teratogenity risk oftopiramate is still largely unknown and there are not enough studies to draw even preliminary conclusions. Preliminary studies failed to report an increased risk for major congenital malformations among gabapentin or.oxcarbazepine exposed pregnancies. Even if raising less concern when compared to valproate, carbamazepine should be avoided for its documented teratogenity risk. Valproate seems to be the worst considering major congenital malformations, specific malformations as,well as its detrimental effects on neurodevelopment. On the other hand, lithium might be considered a good option when treating pregnant women affected by bipolar disorder. Given the limited research on mood stabilizers in pregnancy, clinicians need to be very careful when treating child bearing age women. Clinicians have to balance the potential teratogenityrisk against that of untreated mental illness considering individual circumstances such as severity of illness and risk of relapse.
journal_name
Psychiatr Poljournal_title
Psychiatria polskaauthors
Costoloni G,Pierantozzi E,Goracci A,Bolognesi S,Fagiolini Adoi
10.12740/pp/25834subject
Has Abstractpub_date
2014-09-01 00:00:00pages
865-87issue
5eissn
0033-2674issn
2391-5854journal_volume
48pub_type
杂志文章,评审abstract::This review provides an overview of the concepts, methods and current status of the development of the Eleventh Revision of the Mental and Behavioural Disorders chapter of the International Classification of Diseases and Related Health Problems (ICD-11) by the World Health Organization (WHO). Given the global use of t...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:10.12740/PP/69660
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abstract::In recent years increased interest in the connection of intestinal microflora and the state of human health resulted in a great deal of research on the influence of intestinal microflora in particular on mental health, including works on affective functions of the central nervous system (CNS). Previous studies on anim...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:10.12740/PP/92392
更新日期:2019-04-30 00:00:00
abstract:AIM:Qualitative analysis of acute psychiatric patients' subjective opinions on the conditions and effects of their hospital treatment. Presentation of patients' expectations in this respect and the follow up of the opinion changes taking place during hospital stay. METHOD:Patients' opinions were obtained in open quest...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2006-07-01 00:00:00
abstract::In the article the author would like to draw the readers' attention to one of the central issues of psychoanalysis, i.e. Oedipus complex. In the development of the psychoanalysis the classical conception of Oedipus complex presented by Freud gave rise to a severe criticism both on the part of some psychoanalysts, espe...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:2002-11-01 00:00:00
abstract::Up to 30% of medical students suffer from depression. They have better access to healthcare, but still receive appropriate treatment less frequently than people with depression in the general population. Most of them do not seek medical help as depression is perceived as a stigmatizing disorder, which leads to self-st...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:10.12740/PP/OnlineFirst/67373
更新日期:2017-06-18 00:00:00
abstract:OBJECTIVES:The aim of this study was to identify groups of alcohol-dependent individuals differing in the severity of childhood physical, emotional and sexual abuse and to find the personality variables that discriminate between those groups. METHODS:The study included 90 individuals dependent on alcohol. The followin...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:10.12740/PP/60346
更新日期:2016-10-31 00:00:00
abstract::The aim of the study was the evaluation of concordance between rating and self-rating of attitudes toward psychotic disorders in one hundred patients (72 of them with diagnosis of schizophrenia). At discharge from the hospital patients were examined by two scales: Experience of Illness Scale (for rating) and My Experi...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract:AIM:This study investigated the relation between problem-solving strategies in the marital conflict and marital satisfaction. METHOD:Four problem-solving strategies (Dialogue, Loyalty, Escalation of conflict and Withdrawal) were measured by the Problem-Solving Strategies Inventory, in two versions: self-report and rep...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2006-03-01 00:00:00
abstract::Excessive daytime sleepiness is a serious medical problem. It appears against patient will, when he performs normal day activities. It significantly disturbes daily functioning and may be a cause of a serious accidents. Approximately 5% of the general population suffers from excessive daytime sleepiness. The most comm...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract::Plasma cortisol level was measured 7 times between 3 and 5 pm in 34 inpatients with major depression and 25 controls. 1 mg of dexamethasone per os was administrated the day before a 11 pm. The maximum, minimum, mean and range of cortisol concentration were calculated. All these parameters were statistically significan...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract::The author discusses the metabolism of disulfiram and the enzymes which metabolize ethanol. The restraining of the activity of ALDH in the liver by disulfiram causes an accumulation of acetaldehyde which in their turn cause a series of psychophysical symptoms which are unpleasant and in some instances dangerous for th...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract::On the basis of analyzed clinical material several observations were attempted which were related to the patients' awareness of one's own affective psychosis. It was discovered that patients with endogenous depression considered themselves to be ill, but only in relation to depression. They usually do not perceive in ...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:1992-05-01 00:00:00
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journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:2007-01-01 00:00:00
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journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
abstract::The antidepressive effect of Hydiphen was evaluated and compared with imipramine in patients with endogenous depression. The Hydiphen group consisted of 23, and imipramine group of 22 subjects. The evaluation was made using psychometric scales, orthostatic test, ecg, and laboratory tests before treatment as well as du...
journal_title:Psychiatria polska
pub_type: 临床试验,杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Authors have analysed 120 inpatients who committed suicidal attempt. Diagnoses in 83 women and 37 men aged between 14 and 73 years according to DSM-V classification were analysed. Patients aged between 14 and 27 constituted 60%, while those more than 28 years old 40% of suicidal attempts. In the outcome of diagnoses t...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::Anxiety and anxiety disorders among people with visual impairment are more frequent than in the general population. It is estimated that . of people with visual impairment face depression and/or anxiety, whereas 4-6% of people are diagnosed with anxiety disorders. The purpose of this paper is analyzing the occurrence ...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:10.12740/PP/OnlineFirst/85408
更新日期:2020-04-30 00:00:00
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journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2014-07-01 00:00:00
abstract:AIM:The aim of the study was to determine the image of female-to-male transsexuals (FtM) in the opinion of women and men. Methods. The questionnaire studies were carried out in a group of 300 students. Respondents answered questions concerning their age, sex, birthplace and the questions related to different aspects of...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2012-09-01 00:00:00
abstract::The article summarizes briefly the most important directions of research in the quality of life (QOL) of schizophrenic patients. Results gained by cited authors seem to confirm that the QOL of these patients is lower in comparison with normal population. Researchers look for factors that would be able to rise the subj...
journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:1996-05-01 00:00:00
abstract:UNLABELLED:AIM : Current studies show that diabetic patients are at greater risk of developing psychiatric disorders than general population. The aim of this study was to evaluate the frequency of depressive symptoms in school-aged children with type 1 diabetes (T1D). METHODS:The study involved 477 children with T1D, ...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:10.12740/PP/35649
更新日期:2015-01-01 00:00:00
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journal_title:Psychiatria polska
pub_type: 杂志文章
doi:10.12740/PP/37438
更新日期:2014-11-01 00:00:00
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journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2002-05-01 00:00:00
abstract::Serum dopamine-beta-hydroxylase (DBH) activity was determined in the following diagnostic groups of patients (DSM-III-R criteria): panic disorder (n = 16), generalized anxiety disorder (n = 10), hypochondrical disorder (n = 16). Twenty healthy persons constituted the control group. Enzyme activity in the group of pani...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract::Computerized tomography of the head and psychological evaluation by use the WAIS, Benton Gestalt Test, and L. Bender battery was performed in 32 bipolar patients. CT revealed structural changes in 90% of subjects while only 47% of patients showed organic features in psychological evaluation. No significant correlation...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract:OBJECTIVES:Psychometric evaluation of reliability and usefulness of the Polish version of the CESD-R - a revised version of the CES-D - screening test for depression. METHODS:In an online survey the CESD-R and the Beck Depression Inventory were applied to 260 participants (men and women). Reliability was assessed with...
journal_title:Psychiatria polska
pub_type: 杂志文章
doi:10.12740/PP/61614
更新日期:2016-12-23 00:00:00
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journal_title:Psychiatria polska
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
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journal_title:Psychiatria polska
pub_type: 杂志文章,评审
doi:
更新日期:2012-05-01 00:00:00
abstract:AIM:Currently, the use of first generation antipsychotics (FGA) is strongly limited. On the other hand, treatment with second generation antipsychotics (SGA) can not be applied in every patient. Therefore, there is an urgent necessity to obtain information about the knowledge and experience of clinicians with regard to...
journal_title:Psychiatria polska
pub_type: 共识发展会议,杂志文章
doi:
更新日期:2012-11-01 00:00:00
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journal_title:Psychiatria polska
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-05-01 00:00:00