Abstract:
:With the advent of novel fabrication technologies, free-standing poly(l-lactic acid) (PLLA) nanosheets have been shown to have enhanced performance over their micro- or macroscale equivalents as tissue engineering and drug delivery constructs. In the present research, the authors investigated the surface degradation behavior of PLLA films as a function of confinement to a quasi-two-dimensional structure, and the degradation behavior of nanoscale PLLA films as a function of the initial molecular weight and depth, using time-of-flight secondary ion mass spectrometry. The authors found that nanofilms exhibit less segregation of shorter chains to the surface than microfilms, due to the constrained geometries of these morphologies. It was also concluded that the degradation rate at the surface of nanofilms related to the inverse of the initial molecular weight, as is the case in bulk-scale systems.
journal_name
Biointerphasesjournal_title
Biointerphasesauthors
Marchany MD,Gardella JA Jr,Kuchera TJdoi
10.1116/1.4908206subject
Has Abstractpub_date
2015-03-20 00:00:00pages
019010issue
1eissn
1934-8630issn
1559-4106journal_volume
10pub_type
杂志文章相关文献
Biointerphases文献大全abstract::The growing interest in artificial bioorganic interfaces as a platform for applications in emerging areas as personalized medicine, clinical diagnostics, biosensing, biofilms, prevention of biofouling, and other fields of bioengineering is the origin of a need for in detail multitechnique characterizations of such lay...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4948341
更新日期:2016-06-02 00:00:00
abstract::The use of nanoparticles is one of the fastest expanding fields in industrial as well as in medical applications, owing to their remarkable characteristics. Silver nanoparticles (AgNPs) are among the most-commercialized nanoparticles because of their antibacterial effects. Laser postionization secondary neutral mass s...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4937466
更新日期:2015-06-15 00:00:00
abstract::Commonly used implants for therapeutic approaches of non-systemically impaired bone do not sufficiently support the healing process of osteoporotic bone. Since strontium (II) has been proven as an effective anti-osteoporotic drug new types of strontium enriched calcium phosphate bone cements were developed. As osteopo...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1186/1559-4106-8-17
更新日期:2013-12-01 00:00:00
abstract::Reliable, direct "sample-to-answer" capture of nucleic acid targets from complex media would greatly improve existing capabilities of DNA microarrays and biosensors. This goal has proven elusive for many current nucleic acid detection technologies attempting to produce assay results directly from complex real-world sa...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.2219110
更新日期:2006-06-01 00:00:00
abstract::The authors present surface engineering modifications through chemistry of poly(methylmethacrylate) (PMMA) that have dramatic effects on the result of surface-bound fluorescence immunoassays, both for specific and nonspecific signals. The authors deduce the most important effect to be clustering of antibodies on the s...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4984010
更新日期:2017-06-06 00:00:00
abstract::Each year, the United States spends about $20 billion to treat people who have been infected with antibiotic resistant bacteria. Even so, the development of new antibiotics has slowed considerably since the mid-20th century. As a result, researchers are looking into developing synthetic compounds and materials with an...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4979918
更新日期:2017-04-20 00:00:00
abstract::Surface plasmon resonance immunosensor for the detection of bacterial cells was first reported in 1998 with high detection limit as much as 107 cfu/ml. Since then, many efforts have been made aiming to lower the detection limit and improve the sensitivity of detection. The aim of this study was to compare the effect o...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4971270
更新日期:2016-12-06 00:00:00
abstract::Shewanella oneidensis MR-1 is a dissimilatory metal-reducing bacterium capable of reducing various metal and sulfur compounds and precipitating them in nanoparticulate form. Here, we report the synthesis of molybdenum disulfide nanomaterials at the site of S. oneidensis biofilms grown in the presence of molybdenum tri...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/6.0000199
更新日期:2020-07-24 00:00:00
abstract::Because dental implant abutments are located at transmucosal sites, their surface should inhibit bacterial accumulation to prevent peri-implantitis. The authors examined the effects of human lactoferrin (LF), an antibacterial protein present in saliva, as an antibacterial coating on the titanium surface and evaluated ...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4867415
更新日期:2014-06-01 00:00:00
abstract::Biological membranes and their related molecular mechanisms are essential for all living organisms. Membranes host numerous proteins and are responsible for the exchange of molecules and ions, cell signaling, and cell compartmentation. Indeed, the plasma membrane delimits the intracellular compartment from the extrace...
journal_title:Biointerphases
pub_type: 杂志文章,评审
doi:10.1116/1.4994299
更新日期:2017-09-28 00:00:00
abstract::Not only bacteria but also fungal pathogens, particularly Candida species, can lead to biofilm infections on biomedical devices. By covalent grafting of the antifungal drug caspofungin, which targets the fungal cell wall, onto solid biomaterials, a surface layer can be created that might be able to provide long-term p...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4933108
更新日期:2015-12-14 00:00:00
abstract::In the present study, we investigated the hydrothermal treatment of titanium with divalent cation solutions and its effect in promoting the adhesion of gingival epithelial cells and fibroblasts in vitro. Gingival keratinocyte-like Sa3 cells or fibroblastic NIH3T3 cells were cultured for 1 h on experimental titanium pl...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1007/s13758-012-0027-9
更新日期:2012-12-01 00:00:00
abstract::Although it is well known that the textural properties of scaffolds play an important role in the process of tissue regeneration, the investigation of such effects remain difficult especially at the micro/nano level. Texture confers the material the additional ability to entrap/concentrate molecules circulating in the...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1007/s13758-012-0037-7
更新日期:2012-12-01 00:00:00
abstract::It has been demonstrated that electric fields can minimize surface adhesion of bacteria, but how they affect the near-surface bacterial dynamics has remained largely overlooked. In the present study, the three-dimensional motions of Escherichia coli (E. coli) HCB1 and HCB1414 near a conductive surface under alternatin...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5078543
更新日期:2019-02-20 00:00:00
abstract::Force spectroscopy has been used to measure the adhesion of Saos-2 cells to a glass surface at different phases of the cell cycle. The cells were synchronized in three phases of the cell cycle: G(1), S, and G(2)M. Cells in these phases were compared with unsynchronized and native mitotic cells. Individual cells were a...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.3139962
更新日期:2009-06-01 00:00:00
abstract::In this work, four triple negative (TN) cell lines, three ER+ and PR+ receptor positive (RP) cell lines, and one ER+, PR+, and HER2+ cell line were chemically distinguished from one another using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and principal component analysis (PCA). PCA scores separation was...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4929633
更新日期:2015-06-28 00:00:00
abstract::This study presents the morphological and chemical modification of the cell structure of aerosolized Escherichia coli treated with a dielectric barrier discharge (DBD). Exposure to DBD results in severe oxidation of the bacteria, leading to the formation of hydroxyl groups and carbonyl groups and a significant reducti...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4941367
更新日期:2016-03-12 00:00:00
abstract::The surface concentration gradient of two extracellular matrix (ECM) macromolecules was developed to study the migratory and morphological responses of astrocytes to molecular cues typically found in the central nervous system injury environment. The gradient, prepared using microcontact printing, was composed of rand...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5001675
更新日期:2017-09-11 00:00:00
abstract::The peculiar Cuvierian tubules of sea cucumbers function as a defense mechanism. They thwart attacks by creating a sticky network composed of elongated tubules within which the potential predator is entangled in a matter of seconds and thus immobilized. Cuvierian tubules are typical instantaneous adhesive organs in wh...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4875731
更新日期:2014-06-01 00:00:00
abstract::Dentin adhesive systems for composite tooth restorations are composed of hydrophilic/hydrophobic monomers, solvents, and photoinitiators. The adhesives undergo phase separation and concomitant compositional change during their application in the wet oral environment; phase separation compromises the quality of the hyb...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5058072
更新日期:2018-12-17 00:00:00
abstract::Herein, the authors report and review polyelectrolyte complex (PEC) nanoparticles (NPs) loaded with zoledronate (ZOL) and simvastatin and their effects on bone cells. PEC NPs are intended for modification of bone substitute materials. For characterization, they can be solution casted on germanium (Ge) substrates servi...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4913195
更新日期:2015-03-23 00:00:00
abstract::There has been much recent interest in the protein "corona," the nonspecific adsorption of proteins on the surface of nanoparticles used in biological applications. This research investigates an analogous DNA corona. We find that particles (200 nm and 1 μm) incubated with DNA form a DNA corona, with a higher concentra...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/6.0000439
更新日期:2020-10-01 00:00:00
abstract::Although protein-stabilized gold nanoclusters (AuNCs) have gathered recent attention as biocompatible peroxidase mimics, their practical utility has been critically limited by the low catalytic activity. Here, the authors have developed a nanohybrid material to significantly enhance the catalytic activity of AuNCs by ...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4974198
更新日期:2017-01-17 00:00:00
abstract::The authors report on the characterization of the charge formation at supported bilayer lipid membranes (sBLMs) prepared from the zwitterionic lipid 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine on planar silicon dioxide substrates. The charging of the sBLMs was studied in KCl solutions of different ionic strengths be...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.3082042
更新日期:2009-01-01 00:00:00
abstract::The kinetics of adsorption and desorption of two highly asymmetrical model peptides were studied at methyl- and carboxylic acid-terminated alkylthiolate self-assembled monolayer (SAM) surfaces on gold. The model peptides were leucine-lysine (LK), α-helical (LKα14), and β-strand (LKβ15) peptides that have a well-define...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.3494080
更新日期:2010-12-01 00:00:00
abstract::Peptide nucleic acids (PNAs) are mimics of oligonucleotides containing a neutral peptidelike backbone and are able to bind complementary DNA targets with high affinity and selectivity. In order to investigate the effect of the ionic strength of the buffer solution, hybridization experiments with PNAs as (catcher) prob...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.2746871
更新日期:2007-06-01 00:00:00
abstract::Magnesium alloys are potential biodegradable implants for biomedical applications, and calcium (Ca) is one kind of ideal element being examined for magnesium alloys and biodegradable ceramic coatings owing to its biocompatibility and mechanical suitability. In this study, microarc oxidation (MAO) coatings were prepare...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5003320
更新日期:2018-01-16 00:00:00
abstract::The application of magnesium alloys as biomaterials is limited by their poor corrosion behavior. Microarc oxidation (MAO) treatment was used to prepare ceramic coatings on ZK60 magnesium alloys in order to overcome the poor corrosion resistance. The process was conducted at different current densities (3.5 and 9.0 A/d...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4889734
更新日期:2014-09-01 00:00:00
abstract::Understanding how platelet activation is regulated is important in the context of cardiovascular disorders and their management with antiplatelet therapy. Recent evidence points to different platelet subpopulations performing different functions. In particular, procoagulant and aggregating subpopulations have been rep...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4953866
更新日期:2016-06-22 00:00:00
abstract::The limit of detection of advanced immunoassays, biochips and micro/nano biodetection devices is impacted by the non-specific adsorption of target molecules at the sample surface. In this paper, we present a simple and versatile low cost method for generating active surfaces composed of antibodies arrays surrounded by...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1186/1559-4106-8-37
更新日期:2013-12-01 00:00:00