Low Levels of Endothelial Progenitor Cells and Their Association with Systemic Inflammation and Monocyte Activation in Older HIV-Infected Men.

abstract：:Vaginal anti-HIV antibody responses may be beneficial, and possibly required, for vaccine-induced protection against HIV infection acquired through receptive vaginal intercourse. We have previously determined that intranasal immunization with a hybrid HIV peptide and cholera toxin induced vaginal anti-HIV IgA response...

journal_title：AIDS research and human retroviruses

authors： Staats HF,Montgomery SP,Palker TJ

更新日期：1997-07-20 00:00:00

abstract：:The induction of both neutralizing antibodies and non-neutralizing antibodies with effector functions, for example, antibody-dependent cellular cytotoxicity (ADCC), is desired in the search for effective vaccines against HIV-1. In the pursuit of novel immunogens capable of inducing an efficient antibody response, rabb...

journal_title：AIDS research and human retroviruses

authors： Karlsson I,Borggren M,Jensen SS,Heyndrickx L,Stewart-Jones G,Scarlatti G,Fomsgaard A

更新日期：2018-02-01 00:00:00

abstract：:Perinatal antiretroviral (ARV) exposure has been related to hyperlactatemia and lactic acidosis in infants born to HIV-infected mothers. Our objective was to determine the incidence of these conditions during the first year of life in uninfected infants born to HIV-infected mothers and compare the data with infants bo...

journal_title：AIDS research and human retroviruses

authors： Soler-Palacín P,Martín-Nalda A,Martínez-Gómez X,Melendo S,Riudor E,Arranz JA,Espiau M,Figueras C

更新日期：2012-08-01 00:00:00

abstract：:Ascorbic acid (ascorbate or vitamin C) has been shown to suppress the induction of HIV in latently infected T lymphocytic cells following stimulation with a tumor promoter (PMA) and inflammatory cytokine (TNF-alpha). To assess whether this inhibition was mediated via modulation of the cellular transcription factor, NF...

journal_title：AIDS research and human retroviruses

authors： Harakeh S,Jariwalla RJ

更新日期：1997-02-10 00:00:00

abstract：:We have evaluated the genetic diversity of HIV-1 strains infecting injecting drug users (IDUs) in Lisbon, Portugal. Heteroduplex mobility assay and/or phylogenetic analysis revealed that env (C2V3C3 or gp41) subtype B is present in 63.7% of the 135 viral samples studied, followed by subtypes G (23.7%), A (6.7%), F (5....

journal_title：AIDS research and human retroviruses

authors： Esteves A,Parreira R,Piedade J,Venenno T,Franco M,Germano de Sousa J,Patrício L,Brum P,Costa A,Canas-Ferreira WF

更新日期：2003-06-01 00:00:00

abstract：:We recently reported a novel adhesion pathway in lymphocytes that is mediated by cyclin-dependent kinase (Cdk) 4 activity and mediates lymphocyte interactions with endothelial matrix. We now demonstrate that HIV-infected lymphocytes also use Cdk4 to mediate spontaneous adhesion to fibronectin and endothelial matrix. W...

journal_title：AIDS research and human retroviruses

authors： Chow YH,Liu L,Schwartz B,Harlan JM,Schnapp LM

更新日期：2012-12-01 00:00:00

abstract：:HIV antigens were detected by immunoelectron microscopy at the surface of human and simian T4 lymphocytes that had been infected in vitro. HIV antigens were detected at the surface of cells exhibiting viral particles but also at the surface of cells before the release of virions. The latter cells may be considered imm...

journal_title：AIDS research and human retroviruses

authors： Desportes I,Bonnet D,Nicol I,Snart R,Sarin P

更新日期：1989-02-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infection has altered both the epidemiology and outcome of enteric opportunistic parasitic infections. This study was done to determine the prevalence and species/genotypes of intestinal coccidian and microsporidial infections among HIV/AIDS patients with diarrhea and/or a history of...

journal_title：AIDS research and human retroviruses

authors： Agholi M,Hatam GR,Motazedian MH

更新日期：2013-01-01 00:00:00

abstract：:Many aspects of HIV-1 pathogenesis are affected by Nef protein activity, and efforts have been made to study variation in the nef gene and how that variation relates to disease outcome. We studied the genetic diversity of the nef gene in distinct clones obtained from the same patient (intrahost) and in sequences obtai...

journal_title：AIDS research and human retroviruses

authors： Cavalieri E,Florido C,Leal E,Machado DM,Camargo M,Diaz RS,Janini LM

更新日期：2009-11-01 00:00:00

abstract：:Serological inspection of Simian T-lymphotropic Virus Type 1 was conducted for a wild colony of Macaca fuscata, which was captured in the middle Honshu, Japan. The increase of positive rate after the juvenile stage with the positive rate reaching 100% (or 35/35) in youngster and adult stages, was observed. This findin...

journal_title：AIDS research and human retroviruses

authors： Eguchi K,Ohsawa K,Fuse Kiyono M,Suzuki J,Kurokawa K,Yamamoto T

更新日期：2011-02-01 00:00:00

abstract：:New HIV infections among younger men who have sex with men (MSM) in the United States are escalating. Data on HIV infections in college students are limited. In 2010, three MSM college students presented to our clinic with primary HIV infection (PHI) in a single month. To determine the number of college students among...

journal_title：AIDS research and human retroviruses

authors： Chan PA,Kazi S,Rana A,Blazar I,Dejong CC,Mayer KH,Huard TK,Carleton K,Gillani F,Alexander N,Parillo Z,Flanigan TP,Kantor R

更新日期：2013-01-01 00:00:00

abstract：:Tumor necrosis factor alpha (TNF-alpha) may be involved in the pathogenesis of metabolic and endocrine changes in HIV infection. Pentoxifylline (PTX) is able to suppress the production of TNF-alpha in vitro. The effect of two dosages of intravenously administered PTX on clinical symptoms and ex vivo LPS-stimulated TNF...

journal_title：AIDS research and human retroviruses

authors： Heijligenberg R,Romijn JA,Ackermans M,Endert E,Timmer JG,Sauerwein HP

更新日期：1998-03-01 00:00:00

abstract：:The aim of this study was to evaluate the impact of HIV-1 very low-level viremia (<50 copies/ml) on the 2-year risk of virological failure. A retrospective analysis including HIV-positive patients presenting two consecutive HIV RNA below 50 copies/ml (outpatient clinic in Italy, first semester of 2010) was performed. ...

journal_title：AIDS research and human retroviruses

authors： Calcagno A,Motta I,Ghisetti V,Lo Re S,Allice T,Marinaro L,Milia MG,Tettoni MC,Trentini L,Orofino G,Salassa B,Di Perri G,Bonora S

更新日期：2015-10-01 00:00:00

abstract：:Interleukin-15 (IL-15) enhances the effector mechanisms of anti-HIV immune responses and thus is considered a potential adjuvant of HIV-1 vaccine. However, there are a lack of data concerning the relationships between IL-15 expression and regulation in HIV-1-infected patients and the course of disease progression. We ...

journal_title：AIDS research and human retroviruses

authors： Tarkowski M,Ferraris L,Martone S,Strambio de Castillia F,Misciagna D,Mazzucchelli RI,Lattuada E,Paraninfo G,Galli M,Riva A,Elvis Study Group.

更新日期：2012-07-01 00:00:00

abstract：:We aim to determine the prevalence of HIV nonsuppression and factors associated with it. This is a cross-sectional multicenter study carried out in January 2016 with data of the VACH Cohort, a registry participated by 23 hospitals from most regions of Spain. The prevalence of HIV nonsuppression, defined as HIV RNA ≥20...

journal_title：AIDS research and human retroviruses

authors： Roca B,Spanish VACH Cohort Group.

更新日期：2020-11-01 00:00:00

abstract：:HIV infection is associated with qualitative and functional immune deficiencies. It has been shown that the in vitro infection of CD4+ cells with HIV was associated with sustained elevation of cAMP and cGMP. In the present report the role of cAMP on HIV replication in MT-4 cells was investigated. The MT-4 cells were i...

journal_title：AIDS research and human retroviruses

authors： Nokta MA,Pollard RB

更新日期：1992-07-01 00:00:00

abstract：:We investigate mutations and correlates according to HIV-1 subtype after virological failure (VF) of standard first-line antiretroviral therapy (ART) (non-nucleoside/nucleotide reverse transcriptase inhibitor [NNRTI] +2 nucleoside/nucleotide reverse transcriptase inhibitor [N(t)RTI]). SECOND-LINE study participants we...

journal_title：AIDS research and human retroviruses

authors： Lam EP,Moore CL,Gotuzzo E,Nwizu C,Kamarulzaman A,Chetchotisakd P,van Wyk J,Teppler H,Kumarasamy N,Molina JM,Emery S,Cooper DA,Boyd MA

更新日期：2016-09-01 00:00:00

abstract：:Studies have demonstrated that HIV-1 isolated from subjects experiencing virologic failure on stavudine (d4T)-containing regimens often contains thymidine analog mutations (TAMs), consisting of reverse transcriptase (RT) mutations M41L, D67N, K70R, L210W, T215Y/F, and K219Q/E, previously associated only with zidovudin...

journal_title：AIDS research and human retroviruses

authors： Ross L,Scarsella A,Raffanti S,Henry K,Becker S,Fisher R,Liao Q,Hirani A,Graham N,St Clair M,Hernandez J,NZT40012 Study Team.

更新日期：2001-08-10 00:00:00

abstract：:This study seeks to analyze nearly full-length viral genomes for distinct genetic characteristics that are unique to local or regional strains and to identify regions that have high variability or are highly conserved. Nearly full length sequences of seven HIV-1 samples were obtained to ascertain the circulating subty...

journal_title：AIDS research and human retroviruses

authors： Roye ME,Amarakoon II,Hamilton CL,Eyzaguirre LM,Figueroa P,Carr JK

更新日期：2011-01-01 00:00:00

abstract：:The structure of the Vpu protein of human immunodeficiency virus type 1 (HIV-1) is composed of a short Nterminal domain (NTD), a transmembrane domain (TM), and a cytoplasmic domain (CD). Previous studies have shown that the Vpu protein from subtype B HIV-1 is transported predominantly to the rough endoplasmic reticulu...

journal_title：AIDS research and human retroviruses

authors： Pacyniak E,Gomez ML,Gomez LM,Mulcahy ER,Jackson M,Hout DR,Wisdom BJ,Stephens EB

更新日期：2005-05-01 00:00:00

abstract：:Interferon-α (IFN-α) plays a vital role in combating viral infections especially in the early control after infection. However, the HIV infection has shown substantial level of suppression of IFN-α secretion during initial phase of infection. The reasons behind this impairment are still obscure. As plasmacytoid dendri...

journal_title：AIDS research and human retroviruses

authors： Dhamanage AS,Thakar MR,Paranjape RS

更新日期：2019-01-01 00:00:00

abstract：:To help in the vaccine development, WHO-UNAIDS launched a program for the isolation and characterization of subtype C viruses, the most prevalent HIV-1 subtype in the world. Isolates were obtained from Brazil, China, India, Israel, and South Africa, countries in which these strains are circulating. In this study we ge...

journal_title：AIDS research and human retroviruses

authors： Sánchez-Merino V,Herrero CC,Amorin-Nink A,von Briesen H,López-Galíndez C,World Health Organization-UNAIDS Network for Isolation and Characterization.

更新日期：2003-01-01 00:00:00

abstract：:The World Health Organizations HIV Drug Resistance (WHO HIVDR) Threshold survey method was used to assess transmitted HIVDR in newly diagnosed HIV-1-infected primigravida women attending the Prevention of Parent to Child Transmission (PPTCT) centers in Kakinada, in whom it is likely that the infection had recently occ...

journal_title：AIDS research and human retroviruses

authors： Thorat SR,Chaturbhuj DN,Hingankar NK,Chandrasekhar V,Koppada R,Datkar SR,Srikantiah P,Garg R,Kabra S,Haldar P,Reddy DC,Bachani D,Tripathy SP,Paranjape RS

更新日期：2011-12-01 00:00:00

abstract：:We analyzed the HIV-1 pol gene from patients in Cape Town to determine the genetic diversity of HIV-1 in the region and to assess the baseline HIV-1 resistance level of treatment-naive patients. Plasma was collected prior to the national antiretroviral therapy (ART) program. RNA was extracted, followed by RT-PCR and a...

journal_title：AIDS research and human retroviruses

authors： Jacobs GB,Laten A,van Rensburg EJ,Bodem J,Weissbrich B,Rethwilm A,Preiser W,Engelbrecht S

更新日期：2008-07-01 00:00:00

abstract：:The genetic diversity of HIV-1 is well documented. Except for the HIV-1 isolate LAV-1BRU, no nucleic acid sequence of a European isolate of HIV-1 has been published to date. To further investigate the extent of the genetic variability and the evolution of HIV-1, we have isolated, cloned, and subsequently sequenced HIV...

journal_title：AIDS research and human retroviruses

authors： Sauermann U,Schneider J,Mous J,Brunckhorst U,Schedel I,Jentsch KD,Hunsmann G

更新日期：1990-06-01 00:00:00

abstract：:Here we report the construction, sequencing, and biological characterization of a molecular clone of HIV-1(92UG001), a virus representative of subtype D strains circulating in Uganda. The virus produced by the clone has an aggressive syncytium-inducing phenotype, which matches that of the parental virus. This phenotyp...

journal_title：AIDS research and human retroviruses

authors： Novelli P,Vella C,Oxford J,Daniels RS

更新日期：2002-01-01 00:00:00

abstract：:Women are now becoming the pivot of the epidemiological spread of HIV infection worldwide, especially in developing countries. Therefore, research to develop an efficient microbicide is now a priority for the prevention of HIV-1 acquisition in exposed women. However, recent disappointing failures in microbicide clinic...

journal_title：AIDS research and human retroviruses

authors： Saidi H,Jenabian MA,Belec L

更新日期：2012-11-01 00:00:00

abstract：:In order to obtain more information about the presence of HIV-1 in mononuclear cells of colostrum, research was carried out on both the HIV-1 genome in the cellular fraction of colostrum and the viral antibody in cell-free colostrum of eight anti-HIV-1 seropositive asymptomatic mothers. In five cases cell fractions of...

journal_title：AIDS research and human retroviruses

authors： Vonesch N,Sturchio E,Humani AC,Cordiali Fei P,Cosenza D,Caprilli F,Pezzella M

更新日期：1992-07-01 00:00:00

abstract：:An aqueous extract of Phyllanthus niruri (Euphorbiaceae) inhibited human immunodeficiency virus type-1 reverse transcriptase (HIV-1-RT). The inhibitor against HIV-1-RT in this plant was purified by combination of three column chromatographies, Sephadex LH-20, cellulose, and reverse-phase high-performance liquid chroma...

journal_title：AIDS research and human retroviruses

authors： Ogata T,Higuchi H,Mochida S,Matsumoto H,Kato A,Endo T,Kaji A,Kaji H

更新日期：1992-11-01 00:00:00

abstract：:We performed an HTLV epidemiological study of 986 individuals from 17 villages from the same state of Salvador, the city with the highest HTLV-1 prevalence in Brazil. The HTLV-1 prevalence was 3.85%, 1.56%, and 1.23% in three villages. Phylogenetic analysis of the LTR region demonstrated that all positive samples anal...

journal_title：AIDS research and human retroviruses

authors： Rego FF,Alcantara LC,Moura Neto JP,Miranda AC,Pereira Ode S,Gonçalves Mde S,Galvão-Castro B

更新日期：2008-05-01 00:00:00